Pantheon - League of Legends Champion
Win Rate
49.5%
Pick Rate
3.8%

Pantheonvs Seraphine

DFighterAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 21, 2026
MethodologyData Methodology

Pantheon vs Seraphine is a decisive matchup in LoL patch 26.7. Seraphine wins with a 56.1% win rate (+12.1%) over Pantheon based on 66 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Pantheon build, runes, laning stats, and strategies for the Pantheon vs Seraphine matchup.

Pantheon Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Pantheon performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 43.9% win rateSeraphine(43.9%)
Pantheon - 43.9% win rate in this matchup
Pantheon
43.9% WR
VS
Seraphine vs Pantheon matchup - 56.1% win rate
Seraphine
56.1% WR

Who Wins the Pantheon vs Seraphine Matchup?

Seraphine wins the Pantheon vs Seraphine matchup
Winner
Seraphine
Matches: 66
43.9%
Win Rate
56.1%
1.5
CS / min
1.4
671
DMG / min
462
11,038
Gold / game
10,057
153
Heal / min
314
621
DMG Mitigated / min
340
0.8
CC / min
1.2
44.0%
Early Game WR
56.0%
43.9%
Late Game WR
56.1%

Pantheon vs Seraphine Matchup Summary

The Pantheon vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 66 recent matches analyzed, Seraphine wins with a 56.1% win rate compared to Pantheon's 43.9%, giving Seraphine a 12.1 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Pantheon players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Seraphine leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Pantheon players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Pantheon vs Seraphine Laning Phase Breakdown

Pantheon wins the laning phase against Seraphine in League of Legends

Pantheon is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Pantheon holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
1.5Pantheon
1.4Seraphine
Pantheon and Seraphine farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
671Pantheon
462Seraphine
Pantheon heavily out-damages Seraphine by 208 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Pantheon's sustained damage advantage take over.
Economy
11,038Pantheon
10,057Seraphine
Pantheon generates a commanding 980 more gold per game than Seraphine. This substantial economic advantage means Pantheon consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.8Pantheon
1.2Seraphine
Seraphine provides 0.4 seconds more crowd control per minute than Pantheon, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Seraphine coordinate with their jungler and control the pace of skirmishes.
Sustain
774Pantheon
654Seraphine
Pantheon heals and mitigates 120 more damage per minute than Seraphine, providing moderate extra durability. This sustain edge allows Pantheon to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Seraphine.

Best Pantheon Build Against Seraphine

Plated Steelcaps is the optimal boots choice against Seraphine, providing the mobility and stats Pantheon needs most in this matchup. The top-performing core items for Pantheon against Seraphine are Sundered Sky, Umbral Glaive and Black Cleaver. This combination gives Pantheon an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Pantheon vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
56.0%
+12.0% advantage
Pantheon early game win ratePantheon44.0%
Seraphine early game win rateSeraphine56.0%
Late Game
Seraphine
56.1%
+12.2% advantage
Pantheon late game win ratePantheon43.9%
Seraphine late game win rateSeraphine56.1%

Seraphine dominates the early game (first 15 minutes) with a commanding 56.0% win rate — a 12.0 percentage point lead over Pantheon. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 56.1% win rate — 12.2 points above Pantheon. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Pantheon players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Pantheon Runes Against Seraphine

Precision rune tree - Pantheon primary runes vs SeraphinePrecision
Conqueror - best Pantheon rune vs SeraphineTriumph - best Pantheon rune vs SeraphineLegend: Haste - best Pantheon rune vs SeraphineCoup de Grace - best Pantheon rune vs Seraphine
Domination rune tree - Pantheon secondary runes vs SeraphineDomination
Cheap Shot - best Pantheon rune vs SeraphineRelentless Hunter - best Pantheon rune vs Seraphine
50.0% WR

The Precision and Domination rune setup gives Pantheon the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Pantheon matchup data for League of Legends patch 26.7. The table below shows Pantheon's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Pantheon build, runes, laning stats, and early vs late game analysis for that specific matchup.

Pantheon matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
58.41%1135.792412,05259.6%57.4%
55.45%1012.266610,63658.7%52.7%
53.26%921.56479,84044.9%62.8%
46.67%751.565210,93146.4%46.8%
41.67%721.66499,78033.3%47.6%
50.00%701.771010,58150.0%50.0%
42.42%665.690212,13554.8%31.4%
43.94%661.567111,03844.0%43.9%
49.21%635.485711,60648.0%50.0%
49.12%571.670410,80747.8%50.0%
47.37%571.570310,35343.5%50.0%
50.00%562.077811,16956.5%45.5%
44.44%541.67049,86544.4%44.4%
34.62%532.683710,60131.8%36.7%
46.15%525.11,01011,32153.9%38.5%
55.77%521.969811,14947.8%62.1%
54.90%514.575310,22557.1%52.2%
52.00%501.475410,29950.0%53.9%
44.90%493.599312,72550.0%41.4%
54.17%481.669810,33044.8%68.4%
51.06%471.463810,34740.0%59.3%
44.68%471.566710,84041.2%46.7%
44.68%473.183412,34025.0%54.8%
62.22%455.790812,11276.2%50.0%
53.33%455.283210,86654.5%52.2%
43.18%443.982311,88459.1%27.3%
60.00%404.888112,23961.1%59.1%
38.46%394.882010,68341.7%33.3%
46.15%391.464310,29858.8%36.4%
48.65%376.088310,81755.0%41.2%
48.65%371.46269,62257.9%38.9%
64.86%371.467610,13060.0%70.6%
61.11%361.571911,89541.7%70.8%
55.56%361.665210,26263.2%47.1%
44.44%361.670711,96345.5%44.0%
44.12%341.779512,15344.4%43.8%
55.88%345.890211,58850.0%62.5%
58.82%344.372411,54260.0%57.9%
48.48%334.397012,37546.1%50.0%
36.36%331.370612,11737.5%35.3%
48.48%331.273010,88063.6%40.9%
50.00%322.661910,71150.0%50.0%
50.00%321.470512,15242.9%55.6%
41.94%314.183111,03947.1%35.7%
41.94%311.163011,81343.8%40.0%
43.33%300.871911,88550.0%37.5%
60.00%304.282610,99247.6%88.9%
58.62%296.081711,36656.3%61.5%
37.93%293.690412,39630.8%43.8%
64.29%281.465611,34258.8%72.7%
28.57%281.364510,29723.1%33.3%
53.57%283.595912,66746.7%61.5%
35.71%282.879511,27236.4%35.3%
67.86%283.385212,31191.7%50.0%
71.43%285.493410,33258.8%90.9%
40.74%272.467410,07450.0%30.8%
44.44%271.378813,06550.0%42.1%
59.26%275.897813,28463.6%56.3%
34.62%265.280211,23127.3%40.0%
61.54%264.794212,05250.0%68.8%
36.00%255.580611,62935.7%36.4%
40.00%254.786012,90222.2%50.0%
44.00%255.494712,17033.3%50.0%
48.00%251.575410,78446.7%50.0%
50.00%243.688412,43360.0%42.9%
62.50%245.21,05411,77369.2%54.5%
78.26%235.387412,15066.7%85.7%
65.22%231.672910,82442.9%75.0%
52.17%233.276411,68758.3%45.5%
47.83%235.61,00812,81571.4%37.5%
43.48%234.681710,08653.9%30.0%
50.00%222.876612,87833.3%56.3%
68.18%221.373712,61257.1%73.3%
31.82%220.957610,80528.6%37.5%
68.18%225.893011,31375.0%64.3%
36.36%225.592310,31038.5%33.3%
52.38%215.386311,60366.7%46.7%
61.90%210.976913,778100.0%50.0%
50.00%204.679210,43560.0%40.0%
45.00%200.965111,60940.0%50.0%
65.00%201.669011,34970.0%60.0%
60.00%204.486912,85550.0%64.3%
45.00%204.589211,05011.1%72.7%
31.58%191.77069,04733.3%28.6%
15.79%191.567212,0110.0%21.4%
61.11%180.884112,79655.6%66.7%
44.44%183.285211,57566.7%33.3%
52.94%171.474610,74950.0%55.6%
47.06%172.174312,92850.0%45.5%
52.94%175.889610,11455.6%50.0%
41.18%170.878412,29442.9%40.0%
56.25%165.487612,95180.0%45.5%
37.50%165.675111,85937.5%37.5%
37.50%162.692111,55325.0%50.0%
43.75%165.893011,76237.5%50.0%
56.25%160.875213,67150.0%58.3%
31.25%165.496113,86360.0%18.2%
53.33%154.37499,87355.6%50.0%
53.33%153.585512,53525.0%63.6%
60.00%155.485013,56975.0%54.5%
78.57%145.699812,48260.0%88.9%
50.00%145.577810,38883.3%25.0%
64.29%141.46179,82762.5%66.7%
35.71%143.371210,50250.0%16.7%
57.14%145.21,09512,66960.0%55.6%
35.71%141.469612,14866.7%12.5%
21.43%144.459010,07320.0%22.2%
28.57%144.689713,67016.7%37.5%
38.46%131.069112,32833.3%42.9%
53.85%130.979313,16350.0%57.1%
38.46%132.26069,51333.3%50.0%
30.77%134.985912,26940.0%25.0%
53.85%134.374810,89462.5%40.0%
16.67%124.880411,72825.0%12.5%
72.73%114.379311,72562.5%100.0%
27.27%113.179212,11150.0%14.3%
54.55%110.859911,12475.0%42.9%
50.00%103.782513,04366.7%42.9%
20.00%101.86309,68616.7%25.0%
50.00%104.795512,05920.0%80.0%
60.00%105.079911,78833.3%71.4%
50.00%105.91,11013,42325.0%66.7%
40.00%106.094512,69450.0%33.3%
60.00%105.08028,26260.0%60.0%
55.56%95.079612,02866.7%50.0%
55.56%95.190910,91157.1%50.0%
44.44%95.490811,48133.3%50.0%
44.44%95.573611,74333.3%66.7%
62.50%85.291713,9590.0%71.4%
62.50%80.968612,33360.0%66.7%
50.00%85.71,06510,83950.0%50.0%
50.00%81.274513,6060.0%66.7%
62.50%82.882811,415100.0%50.0%
57.14%74.47229,13340.0%100.0%
57.14%71.388411,11425.0%100.0%
57.14%73.272611,82250.0%66.7%
85.71%72.275812,01775.0%100.0%
42.86%72.895114,45850.0%40.0%
42.86%74.391714,1130.0%50.0%
57.14%70.774613,01950.0%60.0%
42.86%71.777912,46450.0%40.0%
33.33%63.789912,43350.0%0.0%
50.00%64.477412,32650.0%50.0%
50.00%64.868312,816100.0%25.0%
50.00%60.879312,58966.7%33.3%
33.33%65.066711,57250.0%25.0%
33.33%60.975011,6580.0%50.0%
83.33%60.679613,3340.0%100.0%
100.00%52.490212,862100.0%100.0%
40.00%51.964013,3560.0%50.0%
40.00%54.171012,55766.7%0.0%
80.00%54.47578,94366.7%100.0%

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Pantheon vs Seraphine - Frequently Asked Questions

How does Pantheon do against Seraphine in League of Legends?

Seraphine wins the Pantheon vs Seraphine matchup with a 56.1% win rate compared to Pantheon's 43.9%, a 12.1 percentage point difference. This data is based on 66 recent ranked games in patch 26.7.

How does Pantheon do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Pantheon with a 56.0% win rate versus 44.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Pantheon do against Seraphine in the late game?

In the late game, Seraphine takes over the Pantheon vs Seraphine matchup with a 56.1% win rate compared to 43.9%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Pantheon vs Seraphine matchup?

Seraphine wins the matchup against Pantheon with a 56.1% win rate in League of Legends patch 26.7. The 12.1 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 66 games analyzed.

What is the best Pantheon build against Seraphine?

The best Pantheon build against Seraphine includes Sundered Sky, Umbral Glaive, Black Cleaver with Plated Steelcaps. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Pantheon runes against Seraphine?

The best Pantheon runes against Seraphine use the Precision primary tree with Domination secondary. This rune setup achieves a 50.0% win rate in the Pantheon vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Pantheon counter Seraphine?

No, Pantheon struggles against Seraphine with only a 43.9% win rate. Seraphine has the advantage in this matchup. Pantheon players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Pantheon against Seraphine?

When playing Pantheon against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.