Vaynevs Pantheon
Vayne vs Pantheon is a decisive matchup in LoL patch 26.14. Pantheon wins with a 56.3% win rate (+12.5%) over Vayne based on 16 games. Pantheon wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Pantheon matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Pantheon Matchup?
Vayne vs Pantheon Matchup Summary
The Vayne vs Pantheon matchup is a decisive matchup in League of Legends ranked play. Based on 16 recent matches analyzed, Pantheon wins with a 56.3% win rate compared to Vayne's 43.8%, giving Pantheon a 12.5 percentage point advantage. Game phase dynamics play a critical role here: Pantheon controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Pantheon needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Pantheon leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Pantheon has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Pantheon overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Pantheon Laning Phase Breakdown
Pantheon is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Pantheon holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.
Best Vayne Build Against Pantheon
Berserker's Greaves is the optimal boots choice against Pantheon, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Pantheon are Blade of The Ruined King, Guinsoo's Rageblade and Experimental Hexplate. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Pantheon. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Pantheon matchup.
Early Game vs Late Game
Vayne28.6%
Pantheon71.4%Vayne55.6%Pantheon44.4%Pantheon dominates the early game (first 15 minutes) with a commanding 71.4% win rate — a 42.9 percentage point lead over Vayne. This lopsided early game means Pantheon can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Vayne is far superior in the late game (25+ minutes), boasting a 55.6% win rate — 11.1 points above Pantheon. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Pantheon must aggressively press their early advantage and close out the game before Vayne reaches their scaling breakpoints. If Vayne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Vayne Runes Against Pantheon
Precision
Resolve
The Precision and Resolve rune setup gives Vayne the best tools to compete against Pantheon in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Vayne matchup data for League of Legends patch 26.14. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 48.56% | 348 | 5.8 | 847 | 12,979 | 44.1% | 50.9% | |
| 53.42% | 307 | 5.9 | 839 | 12,940 | 48.8% | 56.6% | |
| 48.20% | 278 | 6.1 | 836 | 13,470 | 41.3% | 51.6% | |
| 47.74% | 243 | 6.2 | 860 | 12,610 | 47.6% | 47.9% | |
| 53.08% | 211 | 6.3 | 878 | 12,621 | 43.0% | 61.0% | |
| 41.53% | 183 | 6.1 | 773 | 12,603 | 38.8% | 43.1% | |
| 52.78% | 144 | 6.1 | 791 | 12,829 | 55.8% | 51.1% | |
| 51.91% | 131 | 6.4 | 881 | 14,083 | 40.9% | 57.5% | |
| 41.41% | 128 | 6.1 | 892 | 12,802 | 38.3% | 43.2% | |
| 49.00% | 100 | 6.3 | 952 | 13,528 | 45.7% | 50.8% | |
| 42.86% | 98 | 6.0 | 825 | 13,131 | 40.0% | 44.1% | |
| 52.75% | 91 | 6.2 | 890 | 12,275 | 55.1% | 50.0% | |
| 50.00% | 88 | 5.7 | 727 | 12,174 | 43.8% | 53.6% | |
| 51.81% | 83 | 6.1 | 910 | 11,362 | 54.5% | 50.0% | |
| 47.50% | 80 | 6.1 | 820 | 12,475 | 45.7% | 48.9% | |
| 60.00% | 65 | 6.0 | 974 | 12,774 | 68.2% | 55.8% | |
| 50.00% | 64 | 6.0 | 847 | 11,777 | 46.1% | 52.6% | |
| 62.50% | 64 | 6.1 | 899 | 12,623 | 66.7% | 58.8% | |
| 33.33% | 60 | 5.7 | 698 | 10,500 | 28.6% | 37.5% | |
| 64.91% | 57 | 6.1 | 1,042 | 12,267 | 60.0% | 68.8% | |
| 50.88% | 57 | 6.1 | 787 | 12,253 | 54.8% | 46.1% | |
| 53.57% | 56 | 5.8 | 725 | 12,485 | 43.5% | 60.6% | |
| 47.17% | 53 | 6.4 | 721 | 12,526 | 33.3% | 58.6% | |
| 45.28% | 53 | 5.7 | 745 | 11,425 | 48.1% | 42.3% | |
| 40.38% | 52 | 6.0 | 807 | 12,805 | 42.9% | 38.7% | |
| 52.00% | 50 | 5.6 | 757 | 10,827 | 71.4% | 37.9% | |
| 24.00% | 50 | 5.5 | 593 | 10,367 | 10.5% | 32.3% | |
| 50.00% | 48 | 6.3 | 804 | 12,299 | 37.5% | 62.5% | |
| 43.48% | 46 | 5.9 | 831 | 13,246 | 40.0% | 46.1% | |
| 64.44% | 45 | 6.6 | 1,356 | 13,355 | 52.9% | 71.4% | |
| 44.19% | 43 | 6.5 | 783 | 12,296 | 42.9% | 45.5% | |
| 48.78% | 41 | 6.2 | 879 | 13,464 | 28.6% | 59.3% | |
| 52.94% | 34 | 6.7 | 896 | 13,048 | 50.0% | 55.6% | |
| 63.64% | 33 | 6.5 | 1,116 | 12,112 | 53.3% | 72.2% | |
| 62.50% | 32 | 6.3 | 819 | 12,631 | 45.5% | 71.4% | |
| 59.38% | 32 | 6.1 | 854 | 12,126 | 88.9% | 47.8% | |
| 38.71% | 31 | 5.7 | 1,025 | 11,464 | 27.3% | 45.0% | |
| 54.84% | 31 | 5.8 | 820 | 11,578 | 20.0% | 71.4% | |
| 67.74% | 31 | 6.0 | 1,055 | 12,463 | 54.5% | 75.0% | |
| 43.33% | 30 | 6.2 | 879 | 12,495 | 36.4% | 47.4% | |
| 53.33% | 30 | 6.5 | 1,296 | 14,350 | 44.4% | 57.1% | |
| 42.86% | 28 | 5.9 | 832 | 12,552 | 36.4% | 47.1% | |
| 66.67% | 27 | 6.3 | 893 | 10,712 | 69.2% | 64.3% | |
| 62.96% | 27 | 6.3 | 1,010 | 10,804 | 57.1% | 69.2% | |
| 51.85% | 27 | 6.6 | 827 | 11,719 | 60.0% | 47.1% | |
| 40.00% | 25 | 5.9 | 1,076 | 12,666 | 55.6% | 31.3% | |
| 66.67% | 24 | 6.3 | 851 | 11,368 | 75.0% | 58.3% | |
| 41.67% | 24 | 6.5 | 982 | 11,958 | 53.9% | 27.3% | |
| 39.13% | 23 | 5.3 | 808 | 11,110 | 11.1% | 57.1% | |
| 43.48% | 23 | 5.9 | 903 | 12,039 | 40.0% | 44.4% | |
| 52.17% | 23 | 6.3 | 716 | 12,158 | 50.0% | 53.3% | |
| 50.00% | 22 | 6.3 | 786 | 12,373 | 50.0% | 50.0% | |
| 50.00% | 22 | 6.3 | 877 | 11,269 | 33.3% | 61.5% | |
| 54.55% | 22 | 6.1 | 944 | 13,476 | 50.0% | 56.3% | |
| 50.00% | 22 | 5.7 | 857 | 10,867 | 66.7% | 38.5% | |
| 61.90% | 21 | 5.7 | 807 | 11,322 | 55.6% | 66.7% | |
| 38.10% | 21 | 6.1 | 885 | 12,478 | 66.7% | 26.7% | |
| 47.62% | 21 | 6.3 | 794 | 14,046 | 33.3% | 50.0% | |
| 40.00% | 20 | 6.1 | 896 | 12,759 | 40.0% | 40.0% | |
| 68.42% | 19 | 6.1 | 951 | 10,335 | 75.0% | 63.6% | |
| 57.89% | 19 | 6.3 | 813 | 12,245 | 50.0% | 63.6% | |
| 50.00% | 18 | 5.8 | 938 | 11,873 | 55.6% | 44.4% | |
| 70.59% | 17 | 6.4 | 1,041 | 13,115 | 80.0% | 66.7% | |
| 56.25% | 16 | 6.5 | 811 | 14,119 | 50.0% | 58.3% | |
| 43.75% | 16 | 5.6 | 733 | 11,696 | 28.6% | 55.6% | |
| 31.25% | 16 | 6.0 | 738 | 11,878 | 40.0% | 27.3% | |
| 62.50% | 16 | 6.2 | 946 | 12,972 | 50.0% | 70.0% | |
| 46.67% | 15 | 6.0 | 661 | 9,616 | 55.6% | 33.3% | |
| 66.67% | 15 | 6.2 | 938 | 14,618 | 25.0% | 81.8% | |
| 78.57% | 14 | 6.8 | 918 | 15,770 | 100.0% | 70.0% | |
| 35.71% | 14 | 6.2 | 906 | 9,942 | 33.3% | 37.5% | |
| 71.43% | 14 | 6.4 | 846 | 13,112 | 42.9% | 100.0% | |
| 64.29% | 14 | 6.1 | 1,149 | 12,061 | 57.1% | 71.4% | |
| 53.85% | 13 | 5.9 | 810 | 13,109 | 33.3% | 60.0% | |
| 53.85% | 13 | 5.4 | 1,017 | 13,231 | 50.0% | 57.1% | |
| 53.85% | 13 | 5.8 | 757 | 10,865 | 75.0% | 20.0% | |
| 50.00% | 12 | 6.3 | 894 | 13,153 | 25.0% | 62.5% | |
| 58.33% | 12 | 6.5 | 863 | 10,158 | 33.3% | 83.3% | |
| 41.67% | 12 | 4.4 | 890 | 10,679 | 50.0% | 25.0% | |
| 54.55% | 11 | 5.7 | 764 | 12,344 | 33.3% | 62.5% | |
| 50.00% | 10 | 6.4 | 838 | 12,063 | 66.7% | 42.9% | |
| 80.00% | 10 | 6.0 | 847 | 12,029 | 100.0% | 66.7% | |
| 33.33% | 9 | 5.0 | 723 | 12,686 | 0.0% | 50.0% | |
| 22.22% | 9 | 4.0 | 782 | 13,444 | 0.0% | 33.3% | |
| 66.67% | 9 | 4.3 | 882 | 14,962 | 100.0% | 62.5% | |
| 77.78% | 9 | 5.5 | 792 | 15,017 | 100.0% | 71.4% | |
| 25.00% | 8 | 6.4 | 866 | 11,042 | 50.0% | 0.0% | |
| 37.50% | 8 | 4.5 | 780 | 11,842 | 50.0% | 33.3% | |
| 12.50% | 8 | 4.4 | 823 | 11,955 | 25.0% | 0.0% | |
| 71.43% | 7 | 6.4 | 795 | 13,702 | 50.0% | 80.0% | |
| 42.86% | 7 | 4.8 | 522 | 10,756 | 33.3% | 50.0% | |
| 33.33% | 6 | 6.0 | 825 | 14,164 | 0.0% | 40.0% | |
| 50.00% | 6 | 3.2 | 462 | 10,339 | 66.7% | 33.3% | |
| 16.67% | 6 | 5.1 | 933 | 11,156 | 33.3% | 0.0% | |
| 50.00% | 6 | 4.0 | 739 | 8,973 | 50.0% | 50.0% | |
| 50.00% | 6 | 3.1 | 630 | 7,383 | 50.0% | 50.0% | |
| 83.33% | 6 | 5.5 | 718 | 14,890 | 100.0% | 80.0% | |
| 66.67% | 6 | 5.9 | 979 | 16,504 | 0.0% | 66.7% | |
| 16.67% | 6 | 4.7 | 846 | 11,283 | 0.0% | 25.0% | |
| 40.00% | 5 | 0.7 | 512 | 11,183 | 33.3% | 50.0% | |
| 0.00% | 5 | 5.7 | 822 | 10,600 | 0.0% | 0.0% | |
| 60.00% | 5 | 6.9 | 792 | 12,100 | 50.0% | 66.7% | |
| 60.00% | 5 | 4.2 | 988 | 15,386 | 0.0% | 60.0% | |
| 40.00% | 5 | 4.5 | 714 | 9,282 | 66.7% | 0.0% | |
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Vayne vs Pantheon - Frequently Asked Questions
How does Vayne do against Pantheon in League of Legends?
Pantheon wins the Vayne vs Pantheon matchup with a 56.3% win rate compared to Vayne's 43.8%, a 12.5 percentage point difference. This data is based on 16 recent ranked games in patch 26.14.
How does Vayne do against Pantheon in the early game?
In the early game, Pantheon has the advantage against Vayne with a 71.4% win rate versus 28.6%. Pantheon players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Pantheon in the late game?
In the late game, Vayne takes over the Vayne vs Pantheon matchup with a 55.6% win rate compared to 44.4%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Pantheon matchup?
Pantheon wins the matchup against Vayne with a 56.3% win rate in League of Legends patch 26.14. The 12.5 percentage point advantage means Pantheon is significantly favored in this lane matchup based on 16 games analyzed.
What is the best Vayne build against Pantheon?
The best Vayne build against Pantheon includes Blade of The Ruined King, Guinsoo's Rageblade, Experimental Hexplate with Berserker's Greaves. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Pantheon?
The best Vayne runes against Pantheon use the Precision primary tree with Resolve secondary. This rune setup achieves a 33.3% win rate in the Vayne vs Pantheon matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Pantheon?
No, Vayne struggles against Pantheon with only a 43.8% win rate. Pantheon has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Pantheon's lead.
How do I play Vayne against Pantheon?
When playing Vayne against Pantheon, play cautiously and avoid Pantheon's power spikes. Focus on safe farming — you outscale Pantheon in the late game. Use the matchup-specific build and runes above to optimize your chances.