Sett - League of Legends Champion
Win Rate
51.5%
Pick Rate
3.5%

Settvs Vayne

SFighterTank
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Sett vs Vayne is a decisive matchup in LoL patch 26.7. Sett wins with a 56.6% win rate (+13.2%) over Vayne based on 53 games. Sett holds the advantage in both the early and late game. Below you'll find the best Sett build, runes, laning stats, and strategies for the Sett vs Vayne matchup.

Sett Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Sett performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 56.6% win rateVayne(56.6%)
Sett - 56.6% win rate in this matchup
Sett
56.6% WR
VS
Vayne vs Sett matchup - 43.4% win rate
Vayne
43.4% WR

Who Wins the Sett vs Vayne Matchup?

Sett wins the Sett vs Vayne matchup
Winner
Sett
Matches: 53
56.6%
Win Rate
43.4%
5.3
CS / min
6.2
680
DMG / min
1,045
11,044
Gold / game
12,467
164
Heal / min
269
1,308
DMG Mitigated / min
563
0.8
CC / min
0.4
55.6%
Early Game WR
44.4%
57.7%
Late Game WR
42.3%

Sett vs Vayne Matchup Summary

The Sett vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 53 recent matches analyzed, Sett wins with a 56.6% win rate compared to Vayne's 43.4%, giving Sett a 13.2 percentage point advantage. Sett dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Sett leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Sett players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Sett vs Vayne Laning Phase Breakdown

Vayne wins the laning phase against Sett in League of Legends

Vayne is favored during the laning phase against Sett, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
5.3Sett
6.2Vayne
Vayne significantly out-farms Sett by 0.8 CS per minute, accumulating an estimated 13 CS lead by mid game. This substantial farming gap gives Vayne a major gold advantage and earlier item completions. Sett players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
680Sett
1,045Vayne
Vayne heavily out-damages Sett by 364 DMG/min, dominating both short trades and all-in fights. Sett should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
11,044Sett
12,467Vayne
Vayne generates a commanding 1,423 more gold per game than Sett. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Sett should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.8Sett
0.4Vayne
Sett provides 0.4 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Sett coordinate with their jungler and control the pace of skirmishes.
Sustain
1,472Sett
832Vayne
Sett vastly out-sustains Vayne, healing and mitigating 640 more damage per minute. This massive durability gap means Sett can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Sett Build Against Vayne

Plated Steelcaps is the optimal boots choice against Vayne, providing the mobility and stats Sett needs most in this matchup. The top-performing core items for Sett against Vayne are Stridebreaker, Blade of The Ruined King and Thornmail. This combination gives Sett an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Sett vs Vayne matchup.

Early Game vs Late Game

Early Game
Sett
55.6%
+11.1% advantage
Sett early game win rateSett55.6%
Vayne early game win rateVayne44.4%
Late Game
Sett
57.7%
+15.4% advantage
Sett late game win rateSett57.7%
Vayne late game win rateVayne42.3%

Sett dominates the early game (first 15 minutes) with a commanding 55.6% win rate — a 11.1 percentage point lead over Vayne. This lopsided early game means Sett can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Sett is far superior in the late game (25+ minutes), boasting a 57.7% win rate — 15.4 points above Vayne. Extended games heavily favor Sett, whose kit and scaling make them a dominant force in team fights and objective control.

Sett holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Sett Runes Against Vayne

Precision rune tree - Sett primary runes vs VaynePrecision
Conqueror - best Sett rune vs VayneTriumph - best Sett rune vs VayneLegend: Alacrity - best Sett rune vs VayneLast Stand - best Sett rune vs Vayne
Resolve rune tree - Sett secondary runes vs VayneResolve
Revitalize - best Sett rune vs VayneSecond Wind - best Sett rune vs Vayne
100.0% WR

Running Precision primary with Resolve secondary allows Sett to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.


Sett matchup data for League of Legends patch 26.7. The table below shows Sett's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Sett build, runes, laning stats, and early vs late game analysis for that specific matchup.

Sett matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.54%3276.696512,11348.5%50.6%
57.84%2055.893912,34761.0%55.7%
58.23%1586.098912,69255.0%60.2%
51.33%1136.293412,39551.2%51.4%
46.15%1046.388911,97934.7%56.4%
53.26%926.51,18112,44443.5%63.0%
52.87%875.474911,53862.1%48.3%
48.28%876.086412,21951.4%46.1%
44.05%846.295712,38133.3%51.0%
43.37%836.084211,54835.9%50.0%
56.79%816.082511,91053.1%59.2%
50.00%806.395811,86646.0%53.5%
57.14%775.987512,37362.1%54.2%
66.22%746.492813,01866.7%65.9%
54.79%736.01,19311,11360.0%48.5%
64.29%706.290112,20067.6%60.6%
50.00%706.21,03613,10257.7%45.5%
53.03%666.489912,12441.4%62.2%
53.97%636.098312,17043.8%64.5%
49.21%635.81,12411,87550.0%48.4%
50.00%626.090911,30053.1%46.7%
63.93%616.41,11612,37353.3%74.2%
53.70%546.994512,78651.7%56.0%
56.60%535.368011,04455.6%57.7%
53.85%525.685611,50546.1%61.5%
54.90%515.683311,43551.9%58.3%
47.06%516.781111,55442.4%55.6%
54.00%506.279112,08534.8%70.4%
48.00%506.31,02111,69345.5%52.9%
55.32%476.386412,07755.0%55.6%
45.45%446.485011,52454.2%35.0%
52.38%426.891712,73578.6%39.3%
45.00%405.789111,69044.4%45.5%
71.79%396.099613,13170.6%72.7%
48.72%396.590111,91441.2%54.5%
55.26%386.096811,60357.9%52.6%
39.47%385.570411,57235.7%41.7%
41.67%365.878411,53841.2%42.1%
51.43%356.51,02311,86555.0%46.7%
60.61%336.21,00913,38750.0%66.7%
50.00%306.61,08014,05254.5%47.4%
44.83%296.088612,03350.0%40.0%
46.43%286.284911,85450.0%43.8%
37.04%275.686312,50625.0%42.1%
40.00%256.175611,32638.5%41.7%
56.52%235.984111,45155.6%57.1%
47.62%215.897513,48562.5%38.5%
60.00%204.688212,32737.5%75.0%
40.00%205.775411,63250.0%33.3%
40.00%205.492612,74337.5%41.7%
52.94%176.282113,74366.7%50.0%
50.00%166.384010,07750.0%50.0%
50.00%165.182811,99320.0%63.6%
60.00%156.21,02013,99760.0%60.0%
46.15%135.981511,78716.7%71.4%
50.00%126.21,10512,33066.7%33.3%
58.33%122.467410,55833.3%83.3%
27.27%116.384714,05925.0%28.6%
45.45%116.177512,24033.3%50.0%
45.45%113.574111,81550.0%42.9%
50.00%105.894711,653100.0%28.6%
10.00%105.41,04212,54420.0%0.0%
30.00%105.474211,04040.0%20.0%
50.00%105.678412,43766.7%25.0%
44.44%92.35977,98742.9%50.0%
66.67%95.474012,14860.0%75.0%
55.56%95.583413,5140.0%62.5%
66.67%95.196812,68360.0%75.0%
22.22%96.276912,15750.0%14.3%
55.56%93.361311,30333.3%66.7%
50.00%84.482612,96250.0%50.0%
12.50%85.593612,2540.0%25.0%
50.00%85.770813,033100.0%20.0%
85.71%77.21,08912,62166.7%100.0%
28.57%74.18579,98940.0%0.0%
42.86%74.61,33014,341100.0%20.0%
71.43%75.181111,72150.0%100.0%
71.43%76.787910,80450.0%100.0%
50.00%65.81,18811,31033.3%66.7%
33.33%65.994114,3900.0%33.3%
16.67%65.886413,4330.0%20.0%
60.00%54.894816,425100.0%50.0%
20.00%56.769812,5700.0%33.3%
60.00%55.156911,765100.0%33.3%
80.00%53.595213,07566.7%100.0%
80.00%52.95409,18966.7%100.0%
60.00%55.39848,71760.0%0.0%
0.00%53.13896,8600.0%0.0%
60.00%55.384113,2030.0%60.0%
60.00%54.91,26315,4680.0%75.0%

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Sett vs Vayne - Frequently Asked Questions

How does Sett do against Vayne in League of Legends?

Sett wins the Sett vs Vayne matchup with a 56.6% win rate compared to Vayne's 43.4%, a 13.2 percentage point difference. This data is based on 53 recent ranked games in patch 26.7.

How does Sett do against Vayne in the early game?

In the early game, Sett has the advantage against Vayne with a 55.6% win rate versus 44.4%. Sett players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Sett do against Vayne in the late game?

In the late game, Sett takes over the Sett vs Vayne matchup with a 57.7% win rate compared to 42.3%. Sett scales better into team fights and objective contests after 25 minutes.

Who wins the Sett vs Vayne matchup?

Sett wins the matchup against Vayne with a 56.6% win rate in League of Legends patch 26.7. The 13.2 percentage point advantage means Sett is significantly favored in this lane matchup based on 53 games analyzed.

What is the best Sett build against Vayne?

The best Sett build against Vayne includes Stridebreaker, Blade of The Ruined King, Thornmail with Plated Steelcaps. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Sett runes against Vayne?

The best Sett runes against Vayne use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Sett vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Sett counter Vayne?

Yes, Sett has a favorable matchup against Vayne with a 56.6% win rate. Sett strongly counters Vayne in lane based on current patch 26.7 data.

How do I play Sett against Vayne?

When playing Sett against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.