- Win Rate
- 50.3%
- Pick Rate
- 4.1%
- Ban Rate
- 3.9%
Sett vs Vayne
- Patch
- 26.22
- Games
- 7,950
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Nov 14, 2026 UTC
- Author
- Dakota Chinnick
- Methodology
- Data Methodology
Sett vs Vayne (Top): Sett wins 38.8% of 129 ranked games over the last 2 patches (gold diff at 15: -151). Patch 26.22 build & runes.
Sett38.8%
Vayne is favored in this matchup: Sett wins 38.8% of 129 games, and the whole 95% range (30.8–47.4%) is on the same side of 50%.
Sett Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Sett performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who wins Sett vs Vayne?
Sett wins 38.8% of these games. With this many games the true rate is most likely between 30.8% and 47.4% (95% range).
- Expected
- 49.8% From both champions' overall Top win rates
- Matchup effect
- −11.0 pts Observed minus expected
- Sample
- 129 games Lane: Top · Patch 26.21–26.22
- vs patch 26.21
- −22.6 pts A real change since last patch
Lane: Top · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.21–26.22 · Oct 27 – Nov 13
The headline win rate covers patches 26.21–26.22 (129 games). The lane, game-length, build and rune sections below use patch 26.22 only (60 games).
Key takeaways
- Vayne is favored in this matchup: Sett wins 38.8% of 129 games, and the whole 95% range (30.8–47.4%) is on the same side of 50%.
- That is 11.0 points worse for Sett than both champions' overall Top win rates predict (49.8%), so the matchup itself works against this pick.
- Neither side reliably wins the lane: the average gold difference at 15 minutes is 151, within the margin of error (59 games).
- Sett players pick Doran's Shield + Health Potion far more often against Vayne: 13.5% of their other Top games, 38.3% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Sett and Vayne played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Sett's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Sett vs Vayne Laning Stats
At 15 minutes
Whole-game averages
Sett vs Vayne Win Rate by Game Length
Sett's win rate against Vayne by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Sett's results against Vayne in short and long games are within the margin of error of each other.
Sett vs Vayne Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)EvenSett gold at 15: −151
- First itemEvenSett: 14.6 min · Vayne: 14.5 min
- Games under 20 minInsufficient data
- 20–30 min gamesInsufficient data
- 30+ min gamesInsufficient data
What Sett Changes Against Vayne
Choices Sett players make noticeably more or less often in this matchup than in their other Top games.
Doran's Shield + Health PotionStarting itemsUsually13.5%vs Vayne38.3%+24.8 pts26.1% WR here
Plated SteelcapsBootsUsually49.5%vs Vayne73.3%+23.8 pts25.0% WR here
Doran's Blade + Health PotionStarting itemsUsually41.2%vs Vayne18.3%−22.8 pts
Flash + IgniteSummoner spellsUsually86.1%vs Vayne65.0%−21.1 pts33.3% WR here
ConquerorKeystoneUsually72.1%vs Vayne51.7%−20.5 pts19.4% WR here
Doran's Shield + Health Potion + Stealth WardStarting itemsUsually7.1%vs Vayne26.7%+19.5 pts
Mercury's TreadsBootsUsually25.2%vs Vayne6.7%−18.6 pts- Q > W > Ethe Q > W > E skill orderSkill priorityUsually87.4%vs Vayne71.7%−15.7 pts27.9% WR here
Best Sett Build vs Vayne
Usual Sett build (Top)
72.1% win rate · 43 games
Against Vayne
Not enough matchup-specific build data: only 6 of 23 Sett games against Vayne carried a complete build, which is too few to recommend an item path from. Use Sett's standard build instead.
- Sett usually completes Stridebreaker first, at 14.6 min (median of 53 games).
- Vayne usually completes Blade of The Ruined King first, at 14.5 min (median of 36 games).
- Skill priority: Q > W > E — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Sett Runes vs Vayne
Usual Sett runes (Top)
Conqueror
54.4% win rate · 252 games
Against Vayne
Too few games for a matchup-specific rune page yet — use the usual page.
Plan your Sett draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions
Sett matchup data for League of Legends patch 26.22. The table below shows Sett's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Sett build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Sett Matchups
Hardest for Sett
Easiest for Sett
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Sett vs Vayne FAQ - Patch 26.21–26.22
Who wins Sett vs Vayne?
Vayne is favored in this matchup: Sett wins 38.8% of 129 games, and the whole 95% range (30.8–47.4%) is on the same side of 50%.
What is Sett's win rate against Vayne?
Sett wins 38.8% of 129 Top games against Vayne on patch 26.21–26.22 (95% range 30.8–47.4%). Based on both champions' overall Top win rates, 49.8% would be expected.
Does Sett counter Vayne?
No — it is the other way around: Sett wins only 38.8% of 129 games against Vayne, and the whole 95% range is below 50%.
Who wins lane, Sett or Vayne?
Neither side reliably wins the lane: the average gold difference at 15 minutes is 151, within the margin of error (59 games).
Does Sett outscale Vayne?
There are too few games of each length to tell yet.
When is Vayne strongest against Sett?
On current data there is no stage of the game where Vayne is ahead of Sett beyond the margin of error.
What should Sett build against Vayne?
There are not enough games for a matchup-specific core, so use Sett's usual Top core: Stridebreaker, Heartsteel, Overlord's Bloodmail. The biggest change against Vayne: Doran's Shield + Health Potion (13.5% usually, 38.3% here).
What runes should Sett use against Vayne?
Use Sett's usual Conqueror page (Precision + Resolve); there are too few games for a matchup-specific page. The biggest change against Vayne: Flash + Ignite (86.1% usually, 65.0% here).