Settvs Vayne
Sett vs Vayne is a decisive matchup in LoL patch 26.14. Vayne wins with a 64.9% win rate (+29.8%) over Sett based on 57 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Sett build, runes, laning stats, and strategies for the Sett vs Vayne matchup.
Sett Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Sett performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Sett vs Vayne Matchup?
Sett vs Vayne Matchup Summary
The Sett vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 57 recent matches analyzed, Vayne wins with a 64.9% win rate compared to Sett's 35.1%, giving Vayne a 29.8 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Sett players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Sett leads by 739 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Sett players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Sett vs Vayne Laning Phase Breakdown
Vayne is favored during the laning phase against Sett, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Sett Build Against Vayne
Plated Steelcaps is the optimal boots choice against Vayne, providing the mobility and stats Sett needs most in this matchup. The top-performing core items for Sett against Vayne are Stridebreaker, Spear of Shojin and Sterak's Gage. This combination gives Sett an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 4 games, proving it to be a reliable item path when facing Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Sett vs Vayne matchup.
Early Game vs Late Game
Sett40.0%
Vayne60.0%Sett31.3%Vayne68.8%Vayne dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Sett. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Vayne is far superior in the late game (25+ minutes), boasting a 68.8% win rate — 37.5 points above Sett. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Sett players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Sett Runes Against Vayne
Precision
Resolve
The Precision and Resolve rune setup gives Sett the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Sett matchup data for League of Legends patch 26.14. The table below shows Sett's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Sett build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 45.45% | 308 | 5.6 | 884 | 11,398 | 46.1% | 45.1% | |
| 50.23% | 219 | 6.2 | 1,011 | 11,859 | 52.8% | 48.4% | |
| 54.29% | 210 | 5.9 | 933 | 11,688 | 58.8% | 50.4% | |
| 54.67% | 150 | 5.8 | 756 | 10,385 | 56.9% | 52.9% | |
| 50.00% | 128 | 5.5 | 780 | 12,363 | 52.6% | 48.9% | |
| 53.28% | 122 | 5.8 | 916 | 11,699 | 50.0% | 55.1% | |
| 50.00% | 118 | 6.3 | 936 | 12,441 | 40.5% | 55.3% | |
| 48.31% | 118 | 6.0 | 894 | 11,341 | 39.1% | 54.2% | |
| 47.79% | 113 | 5.8 | 879 | 11,095 | 50.0% | 45.9% | |
| 57.14% | 112 | 6.4 | 1,373 | 12,165 | 51.2% | 60.6% | |
| 47.57% | 103 | 5.3 | 882 | 10,248 | 39.5% | 53.3% | |
| 51.06% | 94 | 6.0 | 834 | 12,617 | 60.0% | 46.9% | |
| 56.38% | 94 | 5.7 | 1,083 | 11,201 | 60.5% | 52.9% | |
| 56.52% | 92 | 6.1 | 965 | 12,005 | 66.7% | 49.1% | |
| 56.52% | 92 | 6.0 | 974 | 10,923 | 54.8% | 58.0% | |
| 45.65% | 92 | 5.8 | 1,005 | 11,101 | 50.0% | 42.0% | |
| 50.00% | 90 | 5.7 | 1,092 | 10,893 | 50.0% | 50.0% | |
| 43.68% | 87 | 6.2 | 986 | 11,553 | 45.2% | 42.2% | |
| 51.85% | 81 | 6.0 | 976 | 12,056 | 61.8% | 44.7% | |
| 56.00% | 75 | 5.8 | 930 | 11,585 | 50.0% | 59.2% | |
| 48.61% | 72 | 5.7 | 867 | 12,190 | 59.1% | 44.0% | |
| 59.15% | 71 | 5.8 | 847 | 11,891 | 73.9% | 52.1% | |
| 50.70% | 71 | 5.1 | 871 | 10,912 | 50.0% | 51.2% | |
| 52.31% | 65 | 5.8 | 916 | 12,193 | 37.5% | 61.0% | |
| 63.08% | 65 | 6.8 | 971 | 11,992 | 63.0% | 63.2% | |
| 58.73% | 63 | 6.2 | 1,169 | 12,615 | 47.1% | 63.0% | |
| 57.14% | 63 | 6.0 | 1,038 | 12,616 | 52.2% | 60.0% | |
| 42.37% | 59 | 5.6 | 865 | 12,535 | 38.9% | 43.9% | |
| 35.09% | 57 | 5.4 | 720 | 11,082 | 40.0% | 31.3% | |
| 53.70% | 54 | 5.9 | 988 | 12,445 | 68.0% | 41.4% | |
| 38.00% | 50 | 5.9 | 969 | 11,340 | 38.9% | 37.5% | |
| 32.65% | 49 | 6.6 | 854 | 12,277 | 56.3% | 21.2% | |
| 43.75% | 48 | 6.4 | 935 | 12,452 | 35.3% | 48.4% | |
| 47.92% | 48 | 6.1 | 886 | 11,893 | 59.1% | 38.5% | |
| 47.92% | 48 | 6.1 | 823 | 11,446 | 50.0% | 46.1% | |
| 44.68% | 47 | 6.1 | 1,006 | 11,091 | 76.5% | 26.7% | |
| 52.17% | 46 | 5.2 | 857 | 10,198 | 65.0% | 42.3% | |
| 69.57% | 46 | 6.0 | 926 | 12,259 | 71.4% | 68.0% | |
| 53.66% | 41 | 6.0 | 939 | 13,251 | 58.3% | 51.7% | |
| 33.33% | 39 | 6.2 | 941 | 11,564 | 30.0% | 36.8% | |
| 57.89% | 38 | 5.9 | 915 | 10,134 | 66.7% | 50.0% | |
| 54.05% | 37 | 5.6 | 915 | 12,059 | 53.3% | 54.5% | |
| 65.71% | 35 | 5.8 | 886 | 12,703 | 76.9% | 59.1% | |
| 45.71% | 35 | 6.2 | 816 | 12,305 | 30.0% | 52.0% | |
| 59.38% | 32 | 6.2 | 911 | 11,830 | 77.8% | 52.2% | |
| 40.00% | 25 | 5.2 | 959 | 11,842 | 77.8% | 18.8% | |
| 62.50% | 24 | 5.5 | 785 | 12,914 | 50.0% | 65.0% | |
| 37.50% | 24 | 5.6 | 910 | 11,654 | 33.3% | 38.9% | |
| 73.91% | 23 | 5.1 | 905 | 12,590 | 78.6% | 66.7% | |
| 50.00% | 20 | 5.4 | 792 | 11,316 | 55.6% | 45.5% | |
| 33.33% | 18 | 5.0 | 876 | 11,817 | 20.0% | 38.5% | |
| 17.65% | 17 | 3.8 | 680 | 9,903 | 11.1% | 25.0% | |
| 68.75% | 16 | 5.4 | 951 | 10,780 | 50.0% | 80.0% | |
| 37.50% | 16 | 2.3 | 810 | 11,722 | 25.0% | 41.7% | |
| 46.67% | 15 | 5.2 | 987 | 13,321 | 25.0% | 54.5% | |
| 46.67% | 15 | 6.1 | 797 | 12,842 | 33.3% | 50.0% | |
| 60.00% | 15 | 4.5 | 703 | 11,084 | 71.4% | 50.0% | |
| 35.71% | 14 | 6.1 | 868 | 13,293 | 33.3% | 36.4% | |
| 46.15% | 13 | 1.8 | 652 | 10,717 | 0.0% | 60.0% | |
| 38.46% | 13 | 3.6 | 767 | 12,280 | 40.0% | 37.5% | |
| 41.67% | 12 | 3.9 | 705 | 11,938 | 71.4% | 0.0% | |
| 41.67% | 12 | 6.0 | 918 | 12,100 | 60.0% | 28.6% | |
| 33.33% | 12 | 2.8 | 663 | 11,429 | 0.0% | 44.4% | |
| 54.55% | 11 | 6.3 | 964 | 11,540 | 60.0% | 50.0% | |
| 70.00% | 10 | 5.5 | 995 | 11,815 | 60.0% | 80.0% | |
| 55.56% | 9 | 5.5 | 816 | 13,088 | 100.0% | 33.3% | |
| 0.00% | 9 | 5.2 | 744 | 9,760 | 0.0% | 0.0% | |
| 62.50% | 8 | 3.0 | 832 | 10,546 | 66.7% | 50.0% | |
| 75.00% | 8 | 5.1 | 938 | 12,386 | 100.0% | 60.0% | |
| 37.50% | 8 | 4.8 | 827 | 12,506 | 66.7% | 20.0% | |
| 50.00% | 8 | 2.2 | 720 | 9,932 | 33.3% | 100.0% | |
| 25.00% | 8 | 3.3 | 696 | 10,004 | 0.0% | 33.3% | |
| 50.00% | 8 | 5.0 | 732 | 12,959 | 100.0% | 33.3% | |
| 50.00% | 8 | 6.1 | 749 | 13,786 | 0.0% | 50.0% | |
| 57.14% | 7 | 6.3 | 632 | 11,913 | 100.0% | 25.0% | |
| 42.86% | 7 | 5.8 | 921 | 12,948 | 0.0% | 50.0% | |
| 71.43% | 7 | 3.9 | 596 | 11,374 | 100.0% | 50.0% | |
| 57.14% | 7 | 5.7 | 636 | 7,739 | 40.0% | 100.0% | |
| 57.14% | 7 | 5.8 | 839 | 14,056 | 50.0% | 60.0% | |
| 71.43% | 7 | 5.8 | 849 | 9,083 | 60.0% | 100.0% | |
| 42.86% | 7 | 5.1 | 752 | 11,076 | 50.0% | 33.3% | |
| 57.14% | 7 | 5.4 | 930 | 10,538 | 0.0% | 80.0% | |
| 71.43% | 7 | 2.6 | 600 | 9,303 | 66.7% | 75.0% | |
| 71.43% | 7 | 5.3 | 915 | 11,508 | 100.0% | 50.0% | |
| 16.67% | 6 | 2.4 | 781 | 13,088 | 0.0% | 25.0% | |
| 16.67% | 6 | 4.3 | 826 | 10,711 | 0.0% | 25.0% | |
| 16.67% | 6 | 3.4 | 675 | 11,975 | 0.0% | 16.7% | |
| 33.33% | 6 | 5.4 | 941 | 11,454 | 0.0% | 50.0% | |
| 83.33% | 6 | 2.9 | 868 | 13,492 | 0.0% | 83.3% | |
| 50.00% | 6 | 5.4 | 843 | 10,713 | 0.0% | 75.0% | |
| 83.33% | 6 | 4.1 | 614 | 12,978 | 0.0% | 83.3% | |
| 66.67% | 6 | 4.5 | 960 | 12,740 | 0.0% | 66.7% | |
| 40.00% | 5 | 6.0 | 968 | 11,656 | 0.0% | 50.0% | |
| 40.00% | 5 | 3.0 | 562 | 6,320 | 50.0% | 0.0% | |
| 60.00% | 5 | 4.9 | 666 | 10,684 | 100.0% | 33.3% | |
| 40.00% | 5 | 4.7 | 773 | 10,654 | 50.0% | 33.3% | |
| 100.00% | 5 | 3.0 | 730 | 11,023 | 100.0% | 100.0% | |
| 60.00% | 5 | 1.8 | 744 | 9,927 | 66.7% | 50.0% | |
| 60.00% | 5 | 6.9 | 822 | 10,781 | 50.0% | 100.0% | |
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Sett vs Vayne - Frequently Asked Questions
How does Sett do against Vayne in League of Legends?
Vayne wins the Sett vs Vayne matchup with a 64.9% win rate compared to Sett's 35.1%, a 29.8 percentage point difference. This data is based on 57 recent ranked games in patch 26.14.
How does Sett do against Vayne in the early game?
In the early game, Vayne has the advantage against Sett with a 60.0% win rate versus 40.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Sett do against Vayne in the late game?
In the late game, Vayne takes over the Sett vs Vayne matchup with a 68.8% win rate compared to 31.3%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Sett vs Vayne matchup?
Vayne wins the matchup against Sett with a 64.9% win rate in League of Legends patch 26.14. The 29.8 percentage point advantage means Vayne is significantly favored in this lane matchup based on 57 games analyzed.
What is the best Sett build against Vayne?
The best Sett build against Vayne includes Stridebreaker, Spear of Shojin, Sterak's Gage with Plated Steelcaps. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Sett runes against Vayne?
The best Sett runes against Vayne use the Precision primary tree with Resolve secondary. This rune setup achieves a 45.8% win rate in the Sett vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Sett counter Vayne?
No, Sett struggles against Vayne with only a 35.1% win rate. Vayne has the advantage in this matchup. Sett players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.
How do I play Sett against Vayne?
When playing Sett against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.