Vaynevs Sett
Vayne vs Sett is a decisive matchup in LoL patch 26.7. Sett wins with a 56.6% win rate (+13.2%) over Vayne based on 53 games. Sett holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Sett matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Sett(43.4%)Who Wins the Vayne vs Sett Matchup?
Vayne vs Sett Matchup Summary
The Vayne vs Sett matchup is a decisive matchup in League of Legends ranked play. Based on 53 recent matches analyzed, Sett wins with a 56.6% win rate compared to Vayne's 43.4%, giving Sett a 13.2 percentage point advantage. Sett dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Sett leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Sett has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Sett overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Sett Laning Phase Breakdown
Vayne is favored during the laning phase against Sett, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Vayne Build Against Sett
Berserker's Greaves is the optimal boots choice against Sett, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Sett are Blade of The Ruined King, Guinsoo's Rageblade and Experimental Hexplate. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build has a 40.0% win rate across 5 games. While the overall matchup may be difficult, this item path gives Vayne the best chance to compete against Sett. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Sett matchup.
Early Game vs Late Game
Vayne44.4%Sett55.6%Vayne42.3%Sett57.7%Sett dominates the early game (first 15 minutes) with a commanding 55.6% win rate — a 11.1 percentage point lead over Vayne. This lopsided early game means Sett can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Sett is far superior in the late game (25+ minutes), boasting a 57.7% win rate — 15.4 points above Vayne. Extended games heavily favor Sett, whose kit and scaling make them a dominant force in team fights and objective control.
Sett holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Vayne Runes Against Sett
Precision
Resolve
The Precision and Resolve rune setup gives Vayne the best tools to compete against Sett in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Vayne matchup data for League of Legends patch 26.7. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 49.02% | 357 | 6.0 | 817 | 13,231 | 45.3% | 52.0% | |
| 52.47% | 324 | 6.2 | 898 | 13,596 | 49.3% | 55.2% | |
| 48.09% | 314 | 6.2 | 832 | 12,819 | 44.0% | 52.7% | |
| 49.01% | 302 | 5.9 | 825 | 12,937 | 47.5% | 50.3% | |
| 52.94% | 272 | 6.0 | 839 | 13,071 | 52.8% | 53.1% | |
| 45.37% | 227 | 6.4 | 960 | 14,254 | 46.9% | 44.2% | |
| 50.00% | 222 | 6.4 | 937 | 13,717 | 50.0% | 50.0% | |
| 52.71% | 203 | 6.5 | 856 | 13,741 | 48.9% | 56.0% | |
| 52.32% | 151 | 6.5 | 828 | 13,287 | 55.4% | 49.4% | |
| 58.39% | 149 | 6.6 | 953 | 12,700 | 51.6% | 63.5% | |
| 51.30% | 115 | 5.8 | 813 | 13,717 | 61.5% | 42.9% | |
| 47.71% | 109 | 6.0 | 882 | 13,239 | 38.2% | 57.4% | |
| 55.67% | 97 | 6.4 | 880 | 12,625 | 59.6% | 51.1% | |
| 51.55% | 97 | 6.3 | 806 | 12,735 | 52.5% | 50.0% | |
| 50.00% | 94 | 5.9 | 832 | 13,595 | 46.7% | 53.1% | |
| 36.36% | 88 | 6.2 | 790 | 12,983 | 30.0% | 41.7% | |
| 47.44% | 78 | 6.6 | 928 | 13,284 | 46.3% | 48.6% | |
| 61.33% | 75 | 6.6 | 924 | 12,102 | 66.7% | 55.6% | |
| 55.56% | 72 | 6.1 | 858 | 13,247 | 45.2% | 63.4% | |
| 57.35% | 68 | 6.0 | 853 | 13,574 | 56.0% | 58.1% | |
| 36.76% | 68 | 6.2 | 881 | 12,394 | 36.7% | 36.8% | |
| 52.54% | 59 | 6.3 | 837 | 12,518 | 48.5% | 57.7% | |
| 42.37% | 59 | 6.2 | 870 | 12,828 | 34.4% | 51.9% | |
| 38.60% | 57 | 5.7 | 605 | 11,225 | 40.0% | 37.0% | |
| 37.50% | 56 | 5.5 | 601 | 10,770 | 30.4% | 42.4% | |
| 43.40% | 53 | 6.2 | 1,045 | 12,467 | 44.4% | 42.3% | |
| 44.00% | 50 | 6.1 | 886 | 13,061 | 47.8% | 40.7% | |
| 53.06% | 49 | 6.1 | 1,214 | 13,804 | 50.0% | 55.2% | |
| 65.91% | 44 | 6.1 | 869 | 13,292 | 66.7% | 65.4% | |
| 56.82% | 44 | 5.6 | 921 | 14,047 | 61.1% | 53.9% | |
| 43.18% | 44 | 5.7 | 996 | 11,548 | 31.3% | 50.0% | |
| 50.00% | 40 | 6.3 | 848 | 13,584 | 35.3% | 60.9% | |
| 55.00% | 40 | 5.9 | 893 | 14,588 | 23.1% | 70.4% | |
| 57.50% | 40 | 6.3 | 951 | 14,248 | 60.0% | 56.7% | |
| 48.72% | 39 | 6.5 | 952 | 13,491 | 57.9% | 40.0% | |
| 57.89% | 38 | 6.0 | 1,029 | 12,413 | 55.0% | 61.1% | |
| 42.11% | 38 | 6.1 | 923 | 13,741 | 44.4% | 40.0% | |
| 54.05% | 37 | 7.0 | 928 | 11,692 | 52.4% | 56.3% | |
| 40.54% | 37 | 5.8 | 804 | 12,225 | 41.2% | 40.0% | |
| 40.00% | 35 | 5.7 | 1,141 | 11,808 | 38.9% | 41.2% | |
| 55.88% | 34 | 6.5 | 856 | 11,125 | 57.9% | 53.3% | |
| 50.00% | 32 | 6.0 | 986 | 13,599 | 66.7% | 43.5% | |
| 66.67% | 30 | 6.2 | 896 | 12,540 | 50.0% | 81.3% | |
| 56.67% | 30 | 6.2 | 981 | 13,896 | 53.9% | 58.8% | |
| 48.28% | 29 | 6.7 | 858 | 12,180 | 28.6% | 66.7% | |
| 55.17% | 29 | 6.3 | 1,024 | 13,694 | 62.5% | 46.1% | |
| 51.85% | 27 | 5.7 | 984 | 12,391 | 45.5% | 56.3% | |
| 61.54% | 26 | 6.1 | 851 | 11,719 | 61.5% | 61.5% | |
| 64.00% | 25 | 6.0 | 808 | 11,770 | 55.6% | 68.8% | |
| 44.00% | 25 | 6.8 | 927 | 12,263 | 42.9% | 45.5% | |
| 33.33% | 24 | 6.4 | 835 | 11,605 | 41.7% | 25.0% | |
| 56.52% | 23 | 5.5 | 921 | 12,424 | 62.5% | 53.3% | |
| 43.48% | 23 | 6.3 | 837 | 12,921 | 60.0% | 30.8% | |
| 40.91% | 22 | 6.6 | 788 | 11,101 | 41.7% | 40.0% | |
| 52.38% | 21 | 5.9 | 923 | 13,477 | 40.0% | 63.6% | |
| 60.00% | 20 | 5.2 | 909 | 14,352 | 20.0% | 73.3% | |
| 47.37% | 19 | 6.9 | 1,008 | 11,892 | 63.6% | 25.0% | |
| 50.00% | 18 | 6.2 | 732 | 13,045 | 60.0% | 37.5% | |
| 50.00% | 18 | 6.2 | 1,053 | 12,784 | 55.6% | 44.4% | |
| 44.44% | 18 | 6.4 | 837 | 11,795 | 42.9% | 45.5% | |
| 50.00% | 18 | 5.8 | 754 | 12,373 | 28.6% | 63.6% | |
| 76.47% | 17 | 6.9 | 1,021 | 14,296 | 80.0% | 75.0% | |
| 29.41% | 17 | 6.9 | 829 | 11,897 | 37.5% | 22.2% | |
| 41.18% | 17 | 6.0 | 862 | 15,191 | 60.0% | 33.3% | |
| 43.75% | 16 | 6.0 | 838 | 11,773 | 62.5% | 25.0% | |
| 56.25% | 16 | 6.6 | 907 | 11,527 | 57.1% | 55.6% | |
| 37.50% | 16 | 5.4 | 659 | 13,208 | 16.7% | 50.0% | |
| 68.75% | 16 | 6.7 | 937 | 13,925 | 83.3% | 60.0% | |
| 53.33% | 15 | 5.9 | 686 | 11,419 | 37.5% | 71.4% | |
| 73.33% | 15 | 6.4 | 851 | 12,621 | 77.8% | 66.7% | |
| 50.00% | 14 | 5.7 | 851 | 11,114 | 16.7% | 75.0% | |
| 42.86% | 14 | 4.3 | 645 | 12,051 | 14.3% | 71.4% | |
| 53.85% | 13 | 3.3 | 885 | 14,162 | 75.0% | 44.4% | |
| 53.85% | 13 | 5.7 | 1,055 | 13,762 | 50.0% | 55.6% | |
| 58.33% | 12 | 5.6 | 562 | 10,027 | 57.1% | 60.0% | |
| 25.00% | 12 | 4.5 | 862 | 13,083 | 25.0% | 25.0% | |
| 50.00% | 12 | 6.3 | 784 | 13,328 | 33.3% | 66.7% | |
| 27.27% | 11 | 6.2 | 771 | 13,462 | 33.3% | 25.0% | |
| 63.64% | 11 | 6.3 | 874 | 15,826 | 66.7% | 62.5% | |
| 36.36% | 11 | 6.6 | 651 | 10,706 | 50.0% | 20.0% | |
| 45.45% | 11 | 5.5 | 919 | 12,629 | 50.0% | 40.0% | |
| 72.73% | 11 | 6.4 | 745 | 10,850 | 71.4% | 75.0% | |
| 45.45% | 11 | 6.0 | 1,064 | 14,508 | 40.0% | 50.0% | |
| 70.00% | 10 | 6.6 | 996 | 13,490 | 75.0% | 66.7% | |
| 40.00% | 10 | 6.8 | 876 | 13,216 | 33.3% | 50.0% | |
| 55.56% | 9 | 6.3 | 937 | 12,286 | 33.3% | 100.0% | |
| 44.44% | 9 | 6.2 | 1,077 | 15,702 | 100.0% | 28.6% | |
| 33.33% | 9 | 6.8 | 774 | 11,069 | 20.0% | 50.0% | |
| 25.00% | 8 | 5.5 | 693 | 10,378 | 25.0% | 25.0% | |
| 50.00% | 8 | 5.9 | 973 | 8,785 | 33.3% | 100.0% | |
| 37.50% | 8 | 1.9 | 834 | 14,727 | 33.3% | 40.0% | |
| 42.86% | 7 | 5.6 | 901 | 12,809 | 100.0% | 20.0% | |
| 0.00% | 7 | 6.6 | 558 | 10,700 | 0.0% | 0.0% | |
| 42.86% | 7 | 4.6 | 651 | 14,538 | 50.0% | 40.0% | |
| 71.43% | 7 | 6.1 | 682 | 13,126 | 75.0% | 66.7% | |
| 57.14% | 7 | 5.5 | 888 | 12,316 | 25.0% | 100.0% | |
| 57.14% | 7 | 5.4 | 895 | 12,100 | 50.0% | 66.7% | |
| 42.86% | 7 | 4.0 | 773 | 11,643 | 33.3% | 50.0% | |
| 57.14% | 7 | 2.5 | 1,313 | 15,576 | 25.0% | 100.0% | |
| 33.33% | 6 | 4.6 | 570 | 9,105 | 25.0% | 50.0% | |
| 66.67% | 6 | 5.9 | 1,089 | 15,493 | 50.0% | 75.0% | |
| 50.00% | 6 | 5.7 | 762 | 13,182 | 50.0% | 50.0% | |
| 50.00% | 6 | 1.9 | 891 | 14,832 | 100.0% | 40.0% | |
| 16.67% | 6 | 5.3 | 844 | 10,442 | 0.0% | 33.3% | |
| 0.00% | 6 | 5.9 | 795 | 10,724 | 0.0% | 0.0% | |
| 83.33% | 6 | 6.1 | 963 | 11,361 | 100.0% | 50.0% | |
| 50.00% | 6 | 6.3 | 804 | 13,574 | 100.0% | 40.0% | |
| 40.00% | 5 | 4.7 | 939 | 14,778 | 100.0% | 0.0% | |
| 60.00% | 5 | 1.7 | 1,195 | 17,648 | 0.0% | 75.0% | |
| 20.00% | 5 | 1.5 | 691 | 9,378 | 33.3% | 0.0% | |
| 60.00% | 5 | 5.3 | 1,100 | 15,380 | 100.0% | 50.0% | |
| 20.00% | 5 | 6.8 | 915 | 12,553 | 0.0% | 33.3% | |
| 40.00% | 5 | 6.5 | 1,021 | 17,603 | 0.0% | 40.0% | |
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Vayne vs Sett - Frequently Asked Questions
How does Vayne do against Sett in League of Legends?
Sett wins the Vayne vs Sett matchup with a 56.6% win rate compared to Vayne's 43.4%, a 13.2 percentage point difference. This data is based on 53 recent ranked games in patch 26.7.
How does Vayne do against Sett in the early game?
In the early game, Sett has the advantage against Vayne with a 55.6% win rate versus 44.4%. Sett players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Sett in the late game?
In the late game, Sett takes over the Vayne vs Sett matchup with a 57.7% win rate compared to 42.3%. Sett scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Sett matchup?
Sett wins the matchup against Vayne with a 56.6% win rate in League of Legends patch 26.7. The 13.2 percentage point advantage means Sett is significantly favored in this lane matchup based on 53 games analyzed.
What is the best Vayne build against Sett?
The best Vayne build against Sett includes Blade of The Ruined King, Guinsoo's Rageblade, Experimental Hexplate with Berserker's Greaves. This build achieves a 40.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Sett?
The best Vayne runes against Sett use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Sett matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Sett?
No, Vayne struggles against Sett with only a 43.4% win rate. Sett has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Sett's lead.
How do I play Vayne against Sett?
When playing Vayne against Sett, play cautiously and avoid Sett's power spikes. Look for jungle assistance and team-dependent plays since Sett has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.