Vaynevs Sett
Vayne vs Sett is a moderate matchup in LoL patch 26.19. Sett wins with a 51.2% win rate (+2.3%) over Vayne based on 43 games. Sett wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Sett matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who wins Vayne vs Sett?
Vayne wins 54.5% of these games. With this many games the true rate is most likely between 43.5% and 65.2% (95% range).
- Expected
- 47.1% From both champions' overall Top win rates
- Matchup effect
- +7.5 pts Observed minus expected
- Sample
- 77 games Lane: Top
- vs patch 26.18
- +18.2 pts A real change since last patch
Lane: Top · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.19 · Sep 24 – Sep 28
They also met in another lane (Bot): 4 games, Vayne won 75.0%.
Key takeaways
- Current data slightly favors Vayne, but the sample is too limited for a strong conclusion: Vayne wins 54.5% of 77 games (95% range 43.5–65.2%).
- Both champions' overall Top win rates predict 47.1% for Vayne; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Neither side reliably wins the lane: the average gold difference at 15 minutes is 209, within the margin of error (77 games).
- Vayne players pick Tenacity and Slow Resist (defense) far more often against Sett: 3.4% of their other Top games, 10.4% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Vayne and Sett played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Vayne's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Vayne vs Sett Laning Stats
At 15 minutes
Whole-game averages
Vayne vs Sett Win Rate by Game Length
Vayne's win rate against Sett by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Vayne's results against Sett in short and long games are within the margin of error of each other.
Vayne vs Sett Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)EvenVayne gold at 15: +209
- First itemVayneVayne: 14.6 min · Sett: 15.5 min
- Games under 20 minInsufficient data
- 20–30 min gamesInsufficient data
- 30+ min gamesEvenVayne wins 59.1% of 44 games
What Vayne Changes Against Sett
Choices Vayne players make noticeably more or less often in this matchup than in their other Top games.
Tenacity and Slow Resist (defense)Stat shardUsually3.4%vs Sett10.4%+7.0 pts
Legend: AlacrityRuneUsually95.9%vs Sett90.9%−5.0 pts55.7% WR here
Best Vayne Build vs Sett
Usual Vayne build (Top)
59.4% win rate · 138 games
Against Sett
Not enough matchup-specific build data: only 9 of 47 Vayne games against Sett carried a complete build, which is too few to recommend an item path from. Use Vayne's standard build instead.
- Vayne usually completes Blade of The Ruined King first, at 14.6 min (median of 51 games).
- Sett usually completes Stridebreaker first, at 15.5 min (median of 61 games).
- Skill priority: Q > W > E — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Vayne Runes vs Sett
Usual Vayne runes (Top)
Press the Attack
49.8% win rate · 257 games
Against Sett
Lethal Tempo53.7% win rate · 41 games
Plan your Vayne draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions
Vayne matchup data for League of Legends patch 26.19. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Vayne Matchups
Hardest for Vayne
Easiest for Vayne
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Vayne vs Sett FAQ - Patch 26.19
Who wins Vayne vs Sett?
Current data slightly favors Vayne, but the sample is too limited for a strong conclusion: Vayne wins 54.5% of 77 games (95% range 43.5–65.2%).
What is Vayne's win rate against Sett?
Vayne wins 54.5% of 77 Top games against Sett on patch 26.19 (95% range 43.5–65.2%). Based on both champions' overall Top win rates, 47.1% would be expected.
Does Vayne counter Sett?
Not clearly. Vayne wins 54.5% of 77 games against Sett, and the 95% range (43.5–65.2%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Vayne or Sett?
Neither side reliably wins the lane: the average gold difference at 15 minutes is 209, within the margin of error (77 games).
Does Vayne outscale Sett?
There are too few games of each length to tell yet.
When is Sett strongest against Vayne?
On current data there is no stage of the game where Sett is ahead of Vayne beyond the margin of error.
What should Vayne build against Sett?
There are not enough games for a matchup-specific core, so use Vayne's usual Top core: Terminus, Blade of The Ruined King, Guinsoo's Rageblade.
What runes should Vayne use against Sett?
Lethal Tempo with Precision and Resolve — 53.7% over 41 games against Sett. The biggest change against Sett: Tenacity and Slow Resist (defense) (3.4% usually, 10.4% here).