
Vaynevs Sett
Vayne vs Sett is a decisive matchup in LoL patch 26.11. Vayne wins with a 55.8% win rate (+11.6%) over Sett based on 86 games. Sett wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Sett matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Sett Matchup?

Vayne vs Sett Matchup Summary
The Vayne vs Sett matchup is a decisive matchup in League of Legends ranked play. Based on 86 recent matches analyzed, Vayne wins with a 55.8% win rate compared to Sett's 44.2%, giving Vayne a 11.6 percentage point advantage. Game phase dynamics play a critical role here: Sett controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Sett needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Sett leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Sett and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Sett away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Sett Laning Phase Breakdown
Vayne is favored during the laning phase against Sett, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Vayne Build Against Sett
Berserker's Greaves is the optimal boots choice against Sett, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Sett are Terminus, Blade of The Ruined King and Guinsoo's Rageblade. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 7 games — well above average and making it the top item path against Sett. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Sett matchup.
Early Game vs Late Game
Sett dominates the early game (first 15 minutes) with a commanding 56.8% win rate — a 13.5 percentage point lead over Vayne. This lopsided early game means Sett can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Vayne is far superior in the late game (25+ minutes), boasting a 65.3% win rate — 30.6 points above Sett. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Sett must aggressively press their early advantage and close out the game before Vayne reaches their scaling breakpoints. If Vayne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Vayne Runes Against Sett
Running Precision primary with Resolve secondary allows Vayne to press their advantage against Sett, amplifying the strengths that make this a favorable matchup.
Vayne matchup data for League of Legends patch 26.11. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 46.01% | 476 | 6.0 | 789 | 12,875 | 44.3% | 47.4% | |
| 47.20% | 447 | 6.0 | 791 | 12,725 | 45.4% | 48.6% | |
| 46.26% | 428 | 5.7 | 796 | 12,715 | 44.9% | 47.3% | |
| 53.92% | 395 | 6.0 | 857 | 12,968 | 53.2% | 54.6% | |
| 47.85% | 372 | 6.2 | 894 | 13,189 | 46.8% | 48.6% | |
| 52.99% | 351 | 6.2 | 843 | 13,142 | 52.5% | 53.4% | |
| 52.98% | 285 | 6.3 | 904 | 13,456 | 46.2% | 58.8% | |
| 53.90% | 269 | 6.3 | 877 | 13,737 | 48.2% | 58.0% | |
| 52.38% | 189 | 5.9 | 886 | 12,468 | 46.1% | 58.2% | |
| 51.92% | 156 | 6.5 | 913 | 11,989 | 50.0% | 53.4% | |
| 54.30% | 151 | 6.1 | 859 | 13,227 | 58.5% | 51.2% | |
| 50.33% | 151 | 6.1 | 804 | 13,007 | 43.8% | 55.2% | |
| 45.95% | 148 | 5.9 | 780 | 13,603 | 45.3% | 46.3% | |
| 45.38% | 130 | 6.1 | 776 | 13,081 | 38.2% | 50.7% | |
| 47.83% | 115 | 6.4 | 812 | 13,765 | 38.5% | 52.6% | |
| 42.61% | 115 | 6.1 | 781 | 12,082 | 34.0% | 49.2% | |
| 50.88% | 114 | 5.8 | 866 | 12,989 | 41.2% | 58.7% | |
| 45.19% | 104 | 6.4 | 899 | 13,175 | 48.7% | 43.1% | |
| 59.80% | 102 | 6.5 | 854 | 13,189 | 63.5% | 56.0% | |
| 31.00% | 100 | 5.5 | 635 | 10,360 | 11.1% | 47.3% | |
| 45.83% | 96 | 5.8 | 857 | 13,164 | 44.4% | 46.7% | |
| 50.53% | 95 | 6.3 | 1,120 | 12,737 | 51.6% | 50.0% | |
| 58.06% | 93 | 6.3 | 796 | 13,008 | 54.8% | 60.8% | |
| 44.09% | 93 | 5.8 | 625 | 11,330 | 42.4% | 45.0% | |
| 45.56% | 90 | 5.8 | 830 | 11,355 | 43.6% | 47.1% | |
| 45.98% | 87 | 6.3 | 851 | 13,572 | 37.9% | 50.0% | |
| 55.81% | 86 | 6.1 | 899 | 10,748 | 43.2% | 65.3% | |
| 55.95% | 84 | 6.2 | 1,292 | 11,546 | 51.4% | 59.2% | |
| 56.41% | 78 | 6.3 | 883 | 13,435 | 57.1% | 55.8% | |
| 54.84% | 62 | 5.9 | 814 | 12,061 | 58.3% | 52.6% | |
| 45.76% | 59 | 6.2 | 877 | 12,775 | 48.0% | 44.1% | |
| 51.92% | 52 | 6.0 | 913 | 11,592 | 48.1% | 56.0% | |
| 45.10% | 51 | 6.5 | 921 | 12,144 | 40.9% | 48.3% | |
| 52.00% | 50 | 6.0 | 875 | 13,621 | 47.8% | 55.6% | |
| 35.42% | 48 | 6.2 | 721 | 10,982 | 28.0% | 43.5% | |
| 58.33% | 48 | 6.1 | 989 | 11,810 | 64.0% | 52.2% | |
| 45.83% | 48 | 6.2 | 1,005 | 10,838 | 51.9% | 38.1% | |
| 50.00% | 46 | 6.2 | 970 | 13,364 | 47.4% | 51.9% | |
| 58.70% | 46 | 6.2 | 914 | 13,671 | 62.5% | 54.5% | |
| 54.55% | 44 | 6.2 | 874 | 14,063 | 57.1% | 53.3% | |
| 44.19% | 43 | 6.6 | 839 | 13,744 | 55.0% | 34.8% | |
| 26.19% | 42 | 5.9 | 874 | 11,678 | 23.5% | 28.0% | |
| 48.78% | 41 | 5.9 | 836 | 11,644 | 43.5% | 55.6% | |
| 52.50% | 40 | 5.6 | 838 | 13,607 | 37.5% | 56.3% | |
| 38.46% | 39 | 6.7 | 854 | 10,961 | 50.0% | 28.6% | |
| 41.03% | 39 | 6.0 | 743 | 9,571 | 28.6% | 55.6% | |
| 67.57% | 37 | 6.5 | 898 | 11,526 | 62.5% | 76.9% | |
| 45.95% | 37 | 5.6 | 832 | 11,998 | 40.0% | 50.0% | |
| 52.94% | 34 | 6.4 | 759 | 12,245 | 50.0% | 54.5% | |
| 52.94% | 34 | 6.4 | 1,051 | 11,474 | 52.6% | 53.3% | |
| 66.67% | 33 | 6.3 | 938 | 13,524 | 61.5% | 70.0% | |
| 48.48% | 33 | 6.4 | 784 | 11,269 | 50.0% | 46.1% | |
| 48.48% | 33 | 6.5 | 979 | 13,305 | 62.5% | 44.0% | |
| 40.63% | 32 | 5.3 | 820 | 11,344 | 42.1% | 38.5% | |
| 62.50% | 32 | 5.7 | 796 | 13,163 | 41.7% | 75.0% | |
| 40.63% | 32 | 6.2 | 676 | 10,369 | 31.6% | 53.9% | |
| 58.06% | 31 | 6.4 | 849 | 12,138 | 64.3% | 52.9% | |
| 53.33% | 30 | 5.6 | 855 | 12,152 | 55.6% | 52.4% | |
| 60.00% | 30 | 6.0 | 953 | 12,308 | 76.9% | 47.1% | |
| 43.33% | 30 | 6.6 | 646 | 11,441 | 37.5% | 50.0% | |
| 55.56% | 27 | 5.3 | 792 | 11,006 | 50.0% | 60.0% | |
| 48.15% | 27 | 6.2 | 834 | 11,465 | 43.8% | 54.5% | |
| 50.00% | 26 | 5.9 | 693 | 11,801 | 41.7% | 57.1% | |
| 50.00% | 26 | 6.1 | 710 | 11,421 | 46.1% | 53.9% | |
| 30.77% | 26 | 5.3 | 700 | 11,001 | 27.3% | 33.3% | |
| 50.00% | 26 | 5.8 | 834 | 12,301 | 54.5% | 46.7% | |
| 48.00% | 25 | 6.0 | 816 | 12,910 | 20.0% | 66.7% | |
| 44.00% | 25 | 6.4 | 758 | 11,844 | 50.0% | 38.5% | |
| 54.17% | 24 | 6.3 | 991 | 12,325 | 64.3% | 40.0% | |
| 45.83% | 24 | 6.0 | 850 | 11,125 | 57.1% | 30.0% | |
| 56.52% | 23 | 5.7 | 610 | 10,299 | 45.5% | 66.7% | |
| 45.45% | 22 | 6.5 | 734 | 12,184 | 38.5% | 55.6% | |
| 40.91% | 22 | 6.0 | 806 | 12,815 | 44.4% | 38.5% | |
| 42.11% | 19 | 6.2 | 920 | 10,372 | 45.5% | 37.5% | |
| 63.16% | 19 | 6.3 | 870 | 12,589 | 50.0% | 72.7% | |
| 42.11% | 19 | 5.8 | 817 | 12,142 | 57.1% | 33.3% | |
| 61.11% | 18 | 5.6 | 1,008 | 13,433 | 66.7% | 58.3% | |
| 62.50% | 16 | 6.1 | 885 | 11,547 | 62.5% | 62.5% | |
| 80.00% | 15 | 2.2 | 885 | 17,368 | 50.0% | 84.6% | |
| 53.33% | 15 | 6.4 | 985 | 13,301 | 50.0% | 54.5% | |
| 60.00% | 15 | 6.5 | 833 | 11,244 | 37.5% | 85.7% | |
| 46.67% | 15 | 6.6 | 876 | 11,530 | 50.0% | 42.9% | |
| 46.67% | 15 | 5.4 | 916 | 13,992 | 25.0% | 54.5% | |
| 42.86% | 14 | 6.4 | 824 | 13,966 | 75.0% | 30.0% | |
| 42.86% | 14 | 6.0 | 841 | 13,447 | 0.0% | 66.7% | |
| 53.85% | 13 | 6.5 | 849 | 13,506 | 100.0% | 33.3% | |
| 46.15% | 13 | 5.2 | 750 | 11,579 | 50.0% | 42.9% | |
| 66.67% | 12 | 5.6 | 1,025 | 12,928 | 80.0% | 57.1% | |
| 33.33% | 12 | 6.0 | 927 | 11,900 | 33.3% | 33.3% | |
| 54.55% | 11 | 5.6 | 1,002 | 13,298 | 50.0% | 57.1% | |
| 63.64% | 11 | 6.1 | 642 | 10,204 | 50.0% | 80.0% | |
| 54.55% | 11 | 2.9 | 820 | 14,068 | 66.7% | 40.0% | |
| 81.82% | 11 | 6.2 | 775 | 12,783 | 100.0% | 71.4% | |
| 54.55% | 11 | 3.4 | 846 | 13,743 | 33.3% | 62.5% | |
| 54.55% | 11 | 5.5 | 761 | 11,649 | 71.4% | 25.0% | |
| 45.45% | 11 | 5.6 | 915 | 9,808 | 75.0% | 28.6% | |
| 40.00% | 10 | 4.6 | 708 | 11,732 | 50.0% | 25.0% | |
| 60.00% | 10 | 5.7 | 820 | 12,597 | 50.0% | 62.5% | |
| 50.00% | 10 | 3.8 | 771 | 13,237 | 33.3% | 57.1% | |
| 40.00% | 10 | 5.5 | 926 | 11,893 | 40.0% | 40.0% | |
| 66.67% | 9 | 3.8 | 1,039 | 13,798 | 66.7% | 66.7% | |
| 33.33% | 9 | 6.1 | 1,076 | 13,273 | 0.0% | 50.0% | |
| 55.56% | 9 | 6.7 | 930 | 13,145 | 100.0% | 20.0% | |
| 33.33% | 9 | 6.0 | 855 | 13,018 | 33.3% | 33.3% | |
| 55.56% | 9 | 3.9 | 860 | 12,860 | 33.3% | 66.7% | |
| 50.00% | 8 | 5.8 | 870 | 14,565 | 50.0% | 50.0% | |
| 62.50% | 8 | 7.3 | 684 | 11,847 | 66.7% | 50.0% | |
| 50.00% | 8 | 3.2 | 883 | 13,479 | 75.0% | 25.0% | |
| 25.00% | 8 | 5.2 | 690 | 9,102 | 16.7% | 50.0% | |
| 37.50% | 8 | 5.8 | 526 | 9,894 | 50.0% | 25.0% | |
| 57.14% | 7 | 4.0 | 760 | 10,750 | 33.3% | 75.0% | |
| 71.43% | 7 | 3.6 | 743 | 11,425 | 80.0% | 50.0% | |
| 42.86% | 7 | 4.5 | 723 | 11,697 | 33.3% | 50.0% | |
| 28.57% | 7 | 4.5 | 676 | 12,046 | 0.0% | 40.0% | |
| 50.00% | 6 | 3.5 | 781 | 15,022 | 0.0% | 60.0% | |
| 33.33% | 6 | 6.8 | 823 | 13,779 | 0.0% | 50.0% | |
| 33.33% | 6 | 2.9 | 989 | 12,898 | 33.3% | 33.3% | |
| 66.67% | 6 | 5.9 | 1,006 | 14,143 | 50.0% | 75.0% | |
| 20.00% | 5 | 4.7 | 577 | 8,999 | 33.3% | 0.0% | |
| 40.00% | 5 | 2.1 | 611 | 12,290 | 50.0% | 0.0% | |
| 40.00% | 5 | 6.4 | 1,176 | 14,594 | 0.0% | 50.0% | |
| 80.00% | 5 | 6.2 | 1,024 | 13,762 | 100.0% | 66.7% | |
| 40.00% | 5 | 5.9 | 962 | 13,248 | 0.0% | 50.0% | |
| 40.00% | 5 | 6.0 | 673 | 9,218 | 50.0% | 0.0% | |
| 40.00% | 5 | 6.4 | 726 | 9,892 | 40.0% | 0.0% | |
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Vayne vs Sett - Frequently Asked Questions
How does Vayne do against Sett in League of Legends?
Vayne wins the Vayne vs Sett matchup with a 55.8% win rate compared to Sett's 44.2%, a 11.6 percentage point difference. This data is based on 86 recent ranked games in patch 26.11.
How does Vayne do against Sett in the early game?
In the early game, Sett has the advantage against Vayne with a 56.8% win rate versus 43.2%. Sett players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Sett in the late game?
In the late game, Vayne takes over the Vayne vs Sett matchup with a 65.3% win rate compared to 34.7%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Sett matchup?
Vayne wins the matchup against Sett with a 55.8% win rate in League of Legends patch 26.11. The 11.6 percentage point advantage means Vayne is significantly favored in this lane matchup based on 86 games analyzed.
What is the best Vayne build against Sett?
The best Vayne build against Sett includes Terminus, Blade of The Ruined King, Guinsoo's Rageblade with Berserker's Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Sett?
The best Vayne runes against Sett use the Precision primary tree with Resolve secondary. This rune setup achieves a 63.6% win rate in the Vayne vs Sett matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Sett?
Yes, Vayne has a favorable matchup against Sett with a 55.8% win rate. Vayne strongly counters Sett in lane based on current patch 26.11 data.
How do I play Vayne against Sett?
When playing Vayne against Sett, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Sett. Build the recommended items and runes for this specific matchup for the best results.
