- Win Rate
- 51.3%
- Pick Rate
- 1.2%
- Ban Rate
- 0.6%
Zeri vs Vayne
- Patch
- 26.20
- Games
- 2,432
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Oct 17, 2026 UTC
- Methodology
- Data Methodology
- Author
- Dakota Chinnick
Zeri vs Vayne is a moderate matchup in LoL patch 26.20. Vayne wins with a 51.4% win rate (+2.8%) over Zeri based on 72 games. Vayne wins the early laning phase while Zeri scales better into the late game. Below you'll find the best Zeri build, runes, laning stats, and strategies for the Zeri vs Vayne matchup.
Zeri Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Zeri performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who wins Zeri vs Vayne?
Zeri wins 49.3% of these games. With this many games the true rate is most likely between 38.0% and 60.7% (95% range).
- Expected
- 52.3% From both champions' overall Bot win rates
- Matchup effect
- −3.0 pts Observed minus expected
- Sample
- 71 games Lane: Bot
- vs patch 26.19
- −1.5 pts Within normal patch-to-patch noise
Lane: Bot · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.20 · Oct 9 – Oct 17
Key takeaways
- Zeri vs Vayne is an even matchup: Zeri wins 49.3% of 71 games, and the 95% range (38.0–60.7%) comfortably includes 50%.
- Both champions' overall Bot win rates predict 52.3% for Zeri; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Neither side reliably wins the lane: the average gold difference at 15 minutes is 237, within the margin of error (69 games).
- Zeri players pick Cut Down far more often against Vayne: 55.8% of their other Bot games, 71.8% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Zeri and Vayne played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Zeri's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Zeri vs Vayne Laning Stats
At 15 minutes
Whole-game averages
Zeri vs Vayne Win Rate by Game Length
Zeri's win rate against Vayne by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Zeri's results against Vayne in short and long games are within the margin of error of each other.
Zeri vs Vayne Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)EvenZeri gold at 15: +237
- First itemZeriZeri: 12.0 min · Vayne: 12.5 min
- Games under 20 minInsufficient data
- 20–30 min gamesInsufficient data
- 30+ min gamesInsufficient data
What Zeri Changes Against Vayne
Choices Zeri players make noticeably more or less often in this matchup than in their other Bot games.
Cut DownRuneUsually55.8%vs Vayne71.8%+16.1 pts52.9% WR here
Cash BackRuneUsually50.1%vs Vayne64.8%+14.7 pts52.2% WR here
Last StandRuneUsually39.3%vs Vayne25.4%−14.0 pts
InspirationSecondary treeUsually52.7%vs Vayne64.8%+12.1 pts52.2% WR here
Hexoptics C44ItemUsually4.1%vs Vayne14.1%+10.0 pts
Best Zeri Build vs Vayne
Usual Zeri build (Bot)
70.3% win rate · 74 games
Against Vayne
Not enough matchup-specific build data: only 10 of 49 Zeri games against Vayne carried a complete build, which is too few to recommend an item path from. Use Zeri's standard build instead.
- Zeri usually completes Yun Tal Wildarrows first, at 12.0 min (median of 42 games).
- Vayne usually completes Blade of The Ruined King first, at 12.5 min (median of 28 games).
- Skill priority: E > Q > W — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Zeri Runes vs Vayne
Usual Zeri runes (Bot)
Lethal Tempo
54.6% win rate · 588 games
Against Vayne
Lethal Tempo
61.9% win rate · 21 games
Plan your Zeri draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions
Zeri matchup data for League of Legends patch 26.20. The table below shows Zeri's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zeri build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Zeri Matchups
Hardest for Zeri
Easiest for Zeri
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Zeri vs Vayne FAQ - Patch 26.20
Who wins Zeri vs Vayne?
Zeri vs Vayne is an even matchup: Zeri wins 49.3% of 71 games, and the 95% range (38.0–60.7%) comfortably includes 50%.
What is Zeri's win rate against Vayne?
Zeri wins 49.3% of 71 Bot games against Vayne on patch 26.20 (95% range 38.0–60.7%). Based on both champions' overall Bot win rates, 52.3% would be expected.
Does Zeri counter Vayne?
Not clearly. Zeri wins 49.3% of 71 games against Vayne, and the 95% range (38.0–60.7%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Zeri or Vayne?
Neither side reliably wins the lane: the average gold difference at 15 minutes is 237, within the margin of error (69 games).
Does Zeri outscale Vayne?
There are too few games of each length to tell yet.
When is Vayne strongest against Zeri?
On current data there is no stage of the game where Vayne is ahead of Zeri beyond the margin of error.
What should Zeri build against Vayne?
There are not enough games for a matchup-specific core, so use Zeri's usual Bot core: Runaan's Hurricane, Bloodthirster, Lord Dominik's Regards. The biggest change against Vayne: Hexoptics C44 (4.1% usually, 14.1% here).
What runes should Zeri use against Vayne?
Lethal Tempo with Precision and Inspiration — 61.9% over 21 games against Vayne. The biggest change against Vayne: Cut Down (55.8% usually, 71.8% here).