Vaynevs Zeri
Vayne vs Zeri is a decisive matchup in LoL patch 26.4. Zeri wins with a 54.5% win rate (+9.1%) over Vayne based on 66 games. Zeri holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Zeri matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Zeri(45.5%)Who Wins the Vayne vs Zeri Matchup?
Vayne vs Zeri Matchup Summary
The Vayne vs Zeri matchup is a decisive matchup in League of Legends ranked play. Based on 66 recent matches analyzed, Zeri wins with a 54.5% win rate compared to Vayne's 45.5%, giving Zeri a 9.1 percentage point advantage. Zeri dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Vayne leads by 0.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Zeri has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Zeri overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Zeri Laning Phase Breakdown
Zeri is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Zeri holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Early Game vs Late Game
Vayne46.9%Zeri53.1%Vayne44.1%Zeri55.9%Zeri dominates the early game (first 15 minutes) with a commanding 53.1% win rate — a 6.3 percentage point lead over Vayne. This lopsided early game means Zeri can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Zeri is far superior in the late game (25+ minutes), boasting a 55.9% win rate — 11.8 points above Vayne. Extended games heavily favor Zeri, whose kit and scaling make them a dominant force in team fights and objective control.
Zeri holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Vayne Runes Against Zeri
Precision
Resolve
The Precision and Resolve rune setup gives Vayne the best tools to compete against Zeri in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Vayne matchup data for League of Legends patch 26.4. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 50.82% | 732 | 6.1 | 803 | 13,258 | 51.6% | 50.3% | |
| 50.47% | 643 | 5.9 | 819 | 13,610 | 51.8% | 49.5% | |
| 50.16% | 626 | 6.3 | 860 | 13,314 | 48.9% | 51.4% | |
| 53.35% | 529 | 6.1 | 868 | 13,348 | 52.2% | 54.2% | |
| 49.25% | 475 | 6.5 | 904 | 13,936 | 44.6% | 53.5% | |
| 56.36% | 402 | 6.4 | 918 | 13,991 | 52.9% | 59.4% | |
| 46.70% | 395 | 6.0 | 802 | 13,251 | 41.1% | 51.1% | |
| 52.87% | 354 | 6.4 | 922 | 14,147 | 51.2% | 53.9% | |
| 48.04% | 282 | 6.0 | 843 | 13,505 | 56.5% | 42.2% | |
| 51.29% | 271 | 6.5 | 870 | 13,472 | 53.7% | 49.3% | |
| 52.54% | 239 | 6.2 | 888 | 13,139 | 52.5% | 52.6% | |
| 54.25% | 212 | 6.5 | 917 | 14,465 | 58.5% | 51.5% | |
| 51.26% | 200 | 6.2 | 837 | 13,336 | 57.7% | 44.2% | |
| 55.00% | 200 | 6.1 | 821 | 13,161 | 49.5% | 60.0% | |
| 47.40% | 192 | 6.3 | 891 | 13,424 | 49.0% | 45.8% | |
| 55.56% | 181 | 6.0 | 858 | 13,653 | 58.1% | 53.8% | |
| 49.11% | 170 | 6.2 | 873 | 13,702 | 46.5% | 51.0% | |
| 49.63% | 135 | 5.9 | 854 | 14,043 | 46.3% | 51.9% | |
| 55.65% | 115 | 6.1 | 902 | 13,632 | 58.8% | 53.1% | |
| 53.15% | 111 | 6.0 | 842 | 11,670 | 52.9% | 53.3% | |
| 57.41% | 109 | 6.5 | 908 | 12,767 | 54.2% | 60.0% | |
| 50.00% | 106 | 6.2 | 838 | 13,925 | 48.7% | 50.8% | |
| 60.20% | 99 | 6.1 | 994 | 12,481 | 61.9% | 58.9% | |
| 54.74% | 96 | 5.8 | 1,031 | 14,056 | 43.6% | 62.5% | |
| 51.09% | 92 | 6.1 | 914 | 13,612 | 56.1% | 47.1% | |
| 45.65% | 92 | 6.3 | 845 | 13,980 | 43.6% | 47.2% | |
| 51.65% | 91 | 6.4 | 893 | 14,004 | 47.4% | 54.7% | |
| 50.59% | 87 | 6.3 | 949 | 12,103 | 52.9% | 49.0% | |
| 45.88% | 86 | 6.1 | 859 | 13,540 | 56.8% | 37.5% | |
| 45.12% | 83 | 5.7 | 603 | 11,339 | 33.3% | 54.4% | |
| 46.15% | 78 | 6.0 | 897 | 11,415 | 28.9% | 62.5% | |
| 44.16% | 77 | 6.3 | 1,391 | 12,481 | 36.7% | 48.9% | |
| 39.47% | 77 | 6.2 | 885 | 14,180 | 28.0% | 45.1% | |
| 53.73% | 68 | 5.5 | 640 | 11,628 | 26.1% | 68.2% | |
| 45.45% | 66 | 6.6 | 969 | 14,142 | 46.9% | 44.1% | |
| 49.23% | 66 | 6.3 | 1,021 | 12,932 | 52.0% | 47.5% | |
| 53.13% | 64 | 6.0 | 1,005 | 11,451 | 51.5% | 54.8% | |
| 45.31% | 64 | 6.2 | 858 | 13,545 | 44.4% | 46.0% | |
| 50.00% | 64 | 6.3 | 987 | 12,060 | 41.4% | 57.1% | |
| 59.32% | 59 | 6.1 | 997 | 11,684 | 57.1% | 61.3% | |
| 50.00% | 56 | 6.5 | 919 | 13,452 | 55.6% | 44.8% | |
| 50.00% | 54 | 6.4 | 949 | 12,100 | 40.0% | 55.9% | |
| 57.14% | 49 | 6.3 | 843 | 12,077 | 54.2% | 60.0% | |
| 53.06% | 49 | 6.4 | 945 | 12,154 | 60.9% | 46.1% | |
| 47.92% | 48 | 6.3 | 804 | 12,125 | 34.8% | 60.0% | |
| 46.81% | 48 | 6.5 | 970 | 12,453 | 47.6% | 46.1% | |
| 51.06% | 47 | 6.5 | 926 | 11,295 | 46.1% | 57.1% | |
| 51.11% | 45 | 7.2 | 998 | 13,306 | 47.6% | 54.2% | |
| 32.56% | 43 | 5.8 | 700 | 9,815 | 20.7% | 57.1% | |
| 69.77% | 43 | 6.8 | 903 | 15,255 | 71.4% | 69.0% | |
| 51.16% | 43 | 6.1 | 986 | 11,825 | 45.8% | 57.9% | |
| 52.38% | 42 | 6.6 | 877 | 12,788 | 47.6% | 57.1% | |
| 55.00% | 40 | 6.0 | 970 | 11,813 | 55.6% | 54.5% | |
| 55.00% | 40 | 5.8 | 914 | 14,584 | 47.4% | 61.9% | |
| 58.97% | 39 | 6.0 | 810 | 12,831 | 46.7% | 66.7% | |
| 48.65% | 38 | 6.0 | 840 | 11,264 | 47.6% | 50.0% | |
| 43.24% | 37 | 5.7 | 825 | 11,627 | 40.0% | 47.1% | |
| 45.71% | 35 | 6.0 | 946 | 12,638 | 27.3% | 54.2% | |
| 33.33% | 33 | 6.5 | 888 | 13,389 | 20.0% | 39.1% | |
| 48.48% | 33 | 6.0 | 728 | 13,059 | 40.0% | 55.6% | |
| 48.39% | 32 | 6.2 | 927 | 13,031 | 46.1% | 50.0% | |
| 54.84% | 31 | 6.1 | 823 | 11,632 | 50.0% | 58.8% | |
| 46.67% | 30 | 6.0 | 768 | 12,083 | 46.1% | 47.1% | |
| 63.33% | 30 | 6.4 | 886 | 12,702 | 72.7% | 57.9% | |
| 44.44% | 27 | 5.4 | 952 | 12,114 | 58.3% | 33.3% | |
| 50.00% | 26 | 6.5 | 889 | 11,516 | 46.1% | 53.9% | |
| 61.54% | 26 | 6.8 | 1,087 | 14,277 | 62.5% | 61.1% | |
| 46.15% | 26 | 5.2 | 849 | 13,311 | 70.0% | 31.3% | |
| 50.00% | 26 | 6.5 | 792 | 12,810 | 66.7% | 35.7% | |
| 46.15% | 26 | 6.6 | 1,144 | 12,906 | 46.7% | 45.5% | |
| 50.00% | 26 | 6.8 | 1,090 | 14,263 | 66.7% | 41.2% | |
| 50.00% | 24 | 6.1 | 885 | 12,729 | 54.5% | 46.1% | |
| 40.91% | 23 | 6.5 | 876 | 14,599 | 40.0% | 41.7% | |
| 60.87% | 23 | 6.3 | 909 | 14,131 | 63.6% | 58.3% | |
| 52.38% | 22 | 5.5 | 860 | 13,670 | 55.6% | 50.0% | |
| 42.86% | 21 | 6.5 | 845 | 11,534 | 33.3% | 55.6% | |
| 50.00% | 20 | 6.0 | 738 | 10,241 | 54.5% | 44.4% | |
| 63.16% | 19 | 6.3 | 1,061 | 15,663 | 100.0% | 53.3% | |
| 52.63% | 19 | 5.9 | 839 | 12,951 | 42.9% | 58.3% | |
| 52.94% | 17 | 6.0 | 1,020 | 12,523 | 40.0% | 71.4% | |
| 43.75% | 16 | 5.7 | 624 | 10,933 | 25.0% | 62.5% | |
| 62.50% | 16 | 6.8 | 817 | 11,303 | 63.6% | 60.0% | |
| 26.67% | 15 | 6.5 | 666 | 9,617 | 22.2% | 33.3% | |
| 40.00% | 15 | 4.0 | 897 | 12,231 | 57.1% | 25.0% | |
| 35.71% | 14 | 6.4 | 637 | 11,280 | 33.3% | 40.0% | |
| 42.86% | 14 | 6.9 | 846 | 11,763 | 28.6% | 57.1% | |
| 42.86% | 14 | 6.3 | 925 | 11,744 | 42.9% | 42.9% | |
| 38.46% | 13 | 4.7 | 827 | 13,522 | 16.7% | 57.1% | |
| 46.15% | 13 | 5.8 | 961 | 12,416 | 20.0% | 62.5% | |
| 46.15% | 13 | 5.9 | 982 | 14,623 | 42.9% | 50.0% | |
| 50.00% | 12 | 5.7 | 897 | 15,265 | 33.3% | 55.6% | |
| 41.67% | 12 | 6.7 | 976 | 15,743 | 40.0% | 42.9% | |
| 58.33% | 12 | 4.5 | 832 | 12,199 | 50.0% | 62.5% | |
| 58.33% | 12 | 5.9 | 781 | 11,830 | 20.0% | 85.7% | |
| 41.67% | 12 | 4.4 | 763 | 11,164 | 50.0% | 25.0% | |
| 54.55% | 11 | 2.9 | 1,055 | 15,239 | 50.0% | 57.1% | |
| 36.36% | 11 | 6.6 | 750 | 13,007 | 0.0% | 44.4% | |
| 45.45% | 11 | 4.2 | 807 | 12,513 | 50.0% | 40.0% | |
| 36.36% | 11 | 6.3 | 904 | 12,259 | 50.0% | 28.6% | |
| 22.22% | 10 | 4.2 | 658 | 9,348 | 14.3% | 50.0% | |
| 50.00% | 10 | 5.9 | 1,132 | 12,118 | 60.0% | 40.0% | |
| 40.00% | 10 | 4.8 | 773 | 12,409 | 33.3% | 50.0% | |
| 33.33% | 9 | 3.4 | 732 | 12,844 | 0.0% | 42.9% | |
| 44.44% | 9 | 4.4 | 695 | 12,824 | 50.0% | 40.0% | |
| 62.50% | 8 | 6.0 | 660 | 12,870 | 100.0% | 50.0% | |
| 25.00% | 8 | 4.2 | 758 | 11,745 | 0.0% | 66.7% | |
| 62.50% | 8 | 5.8 | 899 | 13,469 | 0.0% | 100.0% | |
| 14.29% | 7 | 6.0 | 1,054 | 15,482 | 0.0% | 16.7% | |
| 71.43% | 7 | 6.6 | 849 | 15,132 | 50.0% | 80.0% | |
| 71.43% | 7 | 4.4 | 834 | 12,500 | 100.0% | 50.0% | |
| 66.67% | 6 | 6.7 | 787 | 13,857 | 50.0% | 75.0% | |
| 33.33% | 6 | 6.9 | 753 | 11,851 | 100.0% | 0.0% | |
| 50.00% | 6 | 5.1 | 957 | 12,106 | 0.0% | 60.0% | |
| 50.00% | 6 | 6.5 | 898 | 10,842 | 75.0% | 0.0% | |
| 33.33% | 6 | 1.2 | 808 | 11,065 | 0.0% | 100.0% | |
| 50.00% | 6 | 4.0 | 775 | 15,502 | 100.0% | 40.0% | |
| 60.00% | 5 | 6.3 | 1,180 | 19,865 | 0.0% | 60.0% | |
| 25.00% | 5 | 2.4 | 567 | 11,133 | 50.0% | 0.0% | |
| 40.00% | 5 | 6.3 | 855 | 11,531 | 0.0% | 66.7% | |
| 60.00% | 5 | 6.4 | 1,099 | 15,068 | 100.0% | 33.3% | |
| 40.00% | 5 | 5.1 | 877 | 11,537 | 0.0% | 100.0% | |
| 40.00% | 5 | 3.1 | 1,070 | 12,851 | 50.0% | 0.0% | |
| 40.00% | 5 | 2.7 | 706 | 14,287 | 0.0% | 50.0% | |
| 0.00% | 5 | 6.0 | 781 | 12,150 | 0.0% | 0.0% | |
| 60.00% | 5 | 6.9 | 1,192 | 13,262 | 0.0% | 100.0% | |
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Vayne vs Zeri - Frequently Asked Questions
How does Vayne do against Zeri in League of Legends?
Zeri wins the Vayne vs Zeri matchup with a 54.5% win rate compared to Vayne's 45.5%, a 9.1 percentage point difference. This data is based on 66 recent ranked games in patch 26.4.
How does Vayne do against Zeri in the early game?
In the early game, Zeri has the advantage against Vayne with a 53.1% win rate versus 46.9%. Zeri players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Zeri in the late game?
In the late game, Zeri takes over the Vayne vs Zeri matchup with a 55.9% win rate compared to 44.1%. Zeri scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Zeri matchup?
Zeri wins the matchup against Vayne with a 54.5% win rate in League of Legends patch 26.4. The 9.1 percentage point advantage means Zeri is significantly favored in this lane matchup based on 66 games analyzed.
What is the best Vayne build against Zeri?
The best Vayne build against Zeri includes optimized core items. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Zeri?
The best Vayne runes against Zeri use the Precision primary tree with Resolve secondary. This rune setup achieves a 60.0% win rate in the Vayne vs Zeri matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Zeri?
No, Vayne struggles against Zeri with only a 45.5% win rate. Zeri has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Zeri's lead.
How do I play Vayne against Zeri?
When playing Vayne against Zeri, play cautiously and avoid Zeri's power spikes. Look for jungle assistance and team-dependent plays since Zeri has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.