- Win Rate
- 48.9%
- Pick Rate
- 3.9%
- Ban Rate
- 5.4%
Vayne vs Zeri
- Patch
- 26.20
- Games
- 7,774
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Oct 17, 2026 UTC
- Methodology
- Data Methodology
- Author
- Dakota Chinnick
Vayne vs Zeri is a moderate matchup in LoL patch 26.20. Vayne wins with a 51.4% win rate (+2.8%) over Zeri based on 72 games. Vayne wins the early laning phase while Zeri scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Zeri matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who wins Vayne vs Zeri?
Vayne wins 50.7% of these games. With this many games the true rate is most likely between 39.3% and 62.0% (95% range).
- Expected
- 47.7% From both champions' overall Bot win rates
- Matchup effect
- +3.0 pts Observed minus expected
- Sample
- 71 games Lane: Bot
- vs patch 26.19
- +1.5 pts Within normal patch-to-patch noise
Lane: Bot · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.20 · Oct 9 – Oct 17
Key takeaways
- Vayne vs Zeri is an even matchup: Vayne wins 50.7% of 71 games, and the 95% range (39.3–62.0%) comfortably includes 50%.
- Both champions' overall Bot win rates predict 47.7% for Vayne; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Neither side reliably wins the lane: the average gold difference at 15 minutes is 237, within the margin of error (69 games).
- Vayne players pick Last Stand far more often against Zeri: 1.7% of their other Bot games, 5.6% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Vayne and Zeri played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Vayne's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Vayne vs Zeri Laning Stats
At 15 minutes
Whole-game averages
Vayne vs Zeri Win Rate by Game Length
Vayne's win rate against Zeri by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Vayne's results against Zeri in short and long games are within the margin of error of each other.
Vayne vs Zeri Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)EvenVayne gold at 15: −237
- First itemZeriVayne: 12.5 min · Zeri: 12.0 min
- Games under 20 minInsufficient data
- 20–30 min gamesInsufficient data
- 30+ min gamesInsufficient data
What Vayne Changes Against Zeri
Choices Vayne players make noticeably more or less often in this matchup than in their other Bot games.
Last StandRuneUsually1.7%vs Zeri5.6%+3.9 pts
Best Vayne Build vs Zeri
Usual Vayne build (Bot)
63.3% win rate · 180 games
Against Zeri
Not enough matchup-specific build data: only 6 of 44 Vayne games against Zeri carried a complete build, which is too few to recommend an item path from. Use Vayne's standard build instead.
- Vayne usually completes Blade of The Ruined King first, at 12.5 min (median of 28 games).
- Zeri usually completes Yun Tal Wildarrows first, at 12.0 min (median of 42 games).
- Skill priority: Q > W > E — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Vayne Runes vs Zeri
Usual Vayne runes (Bot)
Lethal Tempo
49.8% win rate · 3,102 games
Against Zeri
Lethal Tempo51.5% win rate · 33 games
Plan your Vayne draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions
Vayne matchup data for League of Legends patch 26.20. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Vayne Matchups
Hardest for Vayne
Easiest for Vayne
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Vayne vs Zeri FAQ - Patch 26.20
Who wins Vayne vs Zeri?
Vayne vs Zeri is an even matchup: Vayne wins 50.7% of 71 games, and the 95% range (39.3–62.0%) comfortably includes 50%.
What is Vayne's win rate against Zeri?
Vayne wins 50.7% of 71 Bot games against Zeri on patch 26.20 (95% range 39.3–62.0%). Based on both champions' overall Bot win rates, 47.7% would be expected.
Does Vayne counter Zeri?
Not clearly. Vayne wins 50.7% of 71 games against Zeri, and the 95% range (39.3–62.0%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Vayne or Zeri?
Neither side reliably wins the lane: the average gold difference at 15 minutes is 237, within the margin of error (69 games).
Does Vayne outscale Zeri?
There are too few games of each length to tell yet.
When is Zeri strongest against Vayne?
Zeri is measurably ahead in: First item.
What should Vayne build against Zeri?
There are not enough games for a matchup-specific core, so use Vayne's usual Bot core: Kraken Slayer, Terminus, Guinsoo's Rageblade.
What runes should Vayne use against Zeri?
Lethal Tempo with Precision and Resolve — 51.5% over 33 games against Zeri. The biggest change against Zeri: Last Stand (1.7% usually, 5.6% here).