Zilean - League of Legends Champion
Win Rate
50.6%
Pick Rate
1.3%

Zileanvs Lissandra

BSupportMage
Patch26.10
Matches1,120,787
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 19, 2026
MethodologyData Methodology

Zilean vs Lissandra is a decisive matchup in LoL patch 26.10. Lissandra wins with a 60.0% win rate (+20.0%) over Zilean based on 5 games. Lissandra wins the early laning phase while Zilean scales better into the late game. Below you'll find the best Zilean build, runes, laning stats, and strategies for the Zilean vs Lissandra matchup.

Zilean Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Zilean performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 40.0% win rateLissandra(40.0%)
Zilean - 40.0% win rate in this matchup
Zilean
40.0% WR
VS
Lissandra vs Zilean matchup - 60.0% win rate
Lissandra
60.0% WR

Who Wins the Zilean vs Lissandra Matchup?

Lissandra wins the Zilean vs Lissandra matchup
Winner
Lissandra
Matches: 5
40.0%
Win Rate
60.0%
3.0
CS / min
3.5
636
DMG / min
755
10,086
Gold / game
11,004
417
Heal / min
206
503
DMG Mitigated / min
452
1.2
CC / min
1.9
33.3%
Early Game WR
66.7%
50.0%
Late Game WR
50.0%

Zilean vs Lissandra Matchup Summary

The Zilean vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Lissandra wins with a 60.0% win rate compared to Zilean's 40.0%, giving Lissandra a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Zilean outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Zilean reaches their power spikes, while Zilean should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra has a strong advantage in this matchup. Zilean players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Lissandra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Zilean vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Zilean in League of Legends

Lissandra is favored during the laning phase against Zilean, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
3.0Zilean
3.5Lissandra
Lissandra edges out Zilean by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
636Zilean
755Lissandra
Lissandra heavily out-damages Zilean by 119 DMG/min, dominating both short trades and all-in fights. Zilean should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Lissandra's sustained damage advantage take over.
Economy
10,086Zilean
11,004Lissandra
Lissandra generates a commanding 918 more gold per game than Zilean. This substantial economic advantage means Lissandra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Zilean should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Zilean
1.9Lissandra
Lissandra provides 0.7 seconds more crowd control per minute than Zilean, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
920Zilean
658Lissandra
Zilean vastly out-sustains Lissandra, healing and mitigating 263 more damage per minute. This massive durability gap means Zilean can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Zilean Build Against Lissandra

Swiftmarch is the optimal boots choice against Lissandra, providing the mobility and stats Zilean needs most in this matchup. The top-performing core items for Zilean against Lissandra are Rod of Ages, Cosmic Drive and Actualizer. This combination gives Zilean an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zilean vs Lissandra matchup.

Early Game vs Late Game

Early Game
Lissandra
66.7%
+33.3% advantage
Zilean early game win rateZilean33.3%
Lissandra early game win rateLissandra66.7%
Late Game
Zilean
50.0%
+0.0% advantage
Zilean late game win rateZilean50.0%
Lissandra late game win rateLissandra50.0%

Lissandra dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Zilean. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Zilean at 50.0% win rate — only 0.0 points ahead of Lissandra. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Lissandra has the edge early, but Zilean gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Zilean Runes Against Lissandra

Sorcery rune tree - Zilean primary runes vs LissandraSorcery
Summon Aery - best Zilean rune vs LissandraManaflow Band - best Zilean rune vs LissandraTranscendence - best Zilean rune vs LissandraWaterwalking - best Zilean rune vs Lissandra
Domination rune tree - Zilean secondary runes vs LissandraDomination
Cheap Shot - best Zilean rune vs LissandraRelentless Hunter - best Zilean rune vs Lissandra
100.0% WR

The Sorcery and Domination rune setup gives Zilean the best tools to compete against Lissandra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Zilean matchup data for League of Legends patch 26.10. The table below shows Zilean's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zilean build, runes, laning stats, and early vs late game analysis for that specific matchup.

Zilean matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.43%1741.73688,94051.8%47.3%
43.88%1391.53698,62848.4%40.3%
55.30%1321.64008,66354.2%56.2%
46.15%1041.63869,07740.9%50.0%
50.00%1041.93679,32448.6%50.8%
52.38%841.63968,50851.1%54.0%
55.70%791.53168,27254.0%57.1%
60.26%781.73809,43961.3%59.6%
50.00%761.53598,98537.0%57.1%
53.95%761.83979,17755.9%52.4%
47.95%731.73679,07243.8%51.2%
44.29%701.53788,99542.3%45.5%
50.88%571.53237,88750.0%52.2%
49.12%571.33428,93942.9%55.2%
62.50%561.53518,36752.2%69.7%
60.00%551.83528,72856.0%63.3%
45.28%531.93868,38647.6%43.8%
34.00%502.13968,25333.3%35.0%
60.42%481.63359,09560.0%60.9%
61.70%471.63739,40257.1%65.4%
34.78%461.43907,94140.7%26.3%
52.17%461.83968,50154.2%50.0%
45.45%441.73699,23760.0%37.9%
46.51%431.74849,01161.1%36.0%
60.00%401.74049,30271.4%53.9%
50.00%361.63518,60023.5%73.7%
54.55%332.53818,75064.7%43.8%
39.29%281.53448,16235.3%45.5%
57.14%281.53969,24972.7%47.1%
45.83%241.93898,97841.7%50.0%
59.09%222.93407,94250.0%70.0%
47.62%211.53759,18825.0%61.5%
55.00%201.33388,58641.7%75.0%
38.89%184.046510,57533.3%41.7%
35.71%141.53978,55233.3%37.5%
57.14%142.041310,47860.0%55.6%
71.43%145.845211,11683.3%62.5%
30.77%132.74328,2100.0%50.0%
53.85%135.965610,23660.0%50.0%
53.85%132.64229,65160.0%50.0%
61.54%131.43549,81475.0%55.6%
23.08%132.43839,1970.0%37.5%
66.67%123.54208,67171.4%60.0%
50.00%122.843311,34525.0%62.5%
58.33%123.24149,31960.0%57.1%
18.18%111.62878,27033.3%0.0%
80.00%105.65209,50450.0%100.0%
44.44%92.639110,60350.0%42.9%
44.44%93.050411,24950.0%42.9%
44.44%91.43958,66875.0%20.0%
87.50%81.75379,76666.7%100.0%
50.00%82.442610,81450.0%50.0%
25.00%86.25169,66220.0%33.3%
87.50%82.96049,34875.0%100.0%
62.50%85.66398,43250.0%75.0%
71.43%74.26459,24466.7%75.0%
57.14%73.841510,48666.7%50.0%
42.86%71.43288,92066.7%25.0%
85.71%73.747911,1100.0%85.7%
42.86%73.53878,55075.0%0.0%
100.00%63.35428,922100.0%100.0%
33.33%63.04099,93566.7%0.0%
50.00%66.34549,65250.0%50.0%
83.33%61.23069,31666.7%100.0%
33.33%63.43979,7530.0%50.0%
50.00%65.64487,68566.7%33.3%
83.33%65.350211,292100.0%75.0%
40.00%56.370412,872100.0%0.0%
40.00%53.063610,08633.3%50.0%
60.00%54.830910,14350.0%66.7%
80.00%51.13889,31950.0%100.0%
60.00%56.14738,37975.0%0.0%
80.00%55.372813,536100.0%66.7%
60.00%53.63837,70750.0%100.0%
60.00%55.352510,21050.0%66.7%
60.00%54.86429,34166.7%50.0%
60.00%54.34769,72750.0%66.7%

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Zilean vs Lissandra - Frequently Asked Questions

How does Zilean do against Lissandra in League of Legends?

Lissandra wins the Zilean vs Lissandra matchup with a 60.0% win rate compared to Zilean's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Zilean do against Lissandra in the early game?

In the early game, Lissandra has the advantage against Zilean with a 66.7% win rate versus 33.3%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Zilean do against Lissandra in the late game?

In the late game, Zilean takes over the Zilean vs Lissandra matchup with a 50.0% win rate compared to 50.0%. Zilean scales better into team fights and objective contests after 25 minutes.

Who wins the Zilean vs Lissandra matchup?

Lissandra wins the matchup against Zilean with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Zilean build against Lissandra?

The best Zilean build against Lissandra includes Rod of Ages, Cosmic Drive, Actualizer with Swiftmarch. Check the matchup breakdown above for the full item path and build order.

What are the best Zilean runes against Lissandra?

The best Zilean runes against Lissandra use the Sorcery primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Zilean vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Zilean counter Lissandra?

No, Zilean struggles against Lissandra with only a 40.0% win rate. Lissandra has the advantage in this matchup. Zilean players should focus on safe farming and avoiding extended trades to minimize Lissandra's lead.

How do I play Zilean against Lissandra?

When playing Zilean against Lissandra, play cautiously and avoid Lissandra's power spikes. Focus on safe farming — you outscale Lissandra in the late game. Use the matchup-specific build and runes above to optimize your chances.