Assassinate Attack

Is Assassinate good in Slay the Spire 2?

In Slay the Spire 2, Assassinate is a rare attack from the Silent card pool. Its effect: Deal 10 damage. Apply 1 Vulnerable. Performance-wise it’s a solid if unspectacular include, rated C tier overall.

Over 462 tracked runs its win rate sits at 34.0%, 20.1% ahead of the 13.8% all-deck baseline. It sees niche play, included in only 2.2% of eligible runs. When it is actually offered players take it 36.1% of the time, and that looks correct: those runs win 39.1% against 33.2% for runs that passed, a +5.7% pick lift over 340 decided runs. Within Silent runs it’s drafted 9.0% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.3 copies on average.

Its standout pairing so far is Mad Science, which lifts its win rate by +26.9% when the two share a deck. On the relic side, Bellows is its standout companion, worth a +28.9% win-rate swing alongside it. It costs 0 energy, gets upgraded 41.0% of the time, and tends to be picked up near floor 17.

Upgrading the card adds +3 Damage, +1 Vulnerable to its stat line. Of the runs that drafted it, 155 ended in victory against 301 deaths and 6 abandons. Its most common run-ender is Test Subject Boss, finishing 6.1% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Assassinate fits a Silent deck.

Pick or Skip: Assassinate

Players take Assassinate in 36.1% of the 1037 offers it appears in; those runs win 39.1% against 33.2% for runs that passed, a pick lift of +5.7% over 340 decided runs.

Taken 374 times out of 1037 offers.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

When to Pick Up Assassinate

Of the 4 pickup windows recorded for Assassinate, Act 3 is the best: 59.3% across 27 runs.

Win rate of runs by the act Assassinate entered the deck. Acts that have not reached the sample floor show their run count only.

Best Cards to Pair with Assassinate

Assassinate’s strongest card pairings so far are Mad Science (+26.9%), Shadowmeld (+24.1%), and Knife Trap (+24.0%), each shown with the win-rate lift it adds.

Mad Science+26.9%35 runsShadowmeld+24.1%33 runsKnife Trap+24.0%71 runsSneaky+21.4%16 runsStorm of Steel+20.5%56 runsTracking+20.3%47 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Assassinate Win Rate by Class

Of the 2 classes that draft Assassinate, it performs best with Silent (33.9%) and Ironclad (29.4%).

The Silent33.9%422 runsThe Ironclad29.4%19 runs

Best Relics for Assassinate

The relics that swing Assassinate’s win rate the most are Bellows (+28.9%), Mummified Hand (+27.8%), and Captain's Wheel (+25.2%), with each lift shown.

Bellows+28.9%25 runsMummified Hand+27.8%24 runsCaptain's Wheel+25.2%17 runsStone Calendar+24.0%21 runsTingsha+23.9%28 runsPantograph+22.9%55 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Assassinate Card Details

A 0-energy rare attack, Assassinate is upgraded 41.0% of the time and tends to enter the deck around floor 17.

Deal 10 damage. Apply 1 Vulnerable.

Upgrade: +3 Damage, +1 Vulnerable

What Ends Runs with Assassinate

Runs holding Assassinate end most often against Test Subject Boss (6.1%), Queen Boss (6.1%), and Kaiser Crab Boss (5.8%) — the share of its runs each accounts for is shown.

• Test Subject Boss6.1% of runs
• Queen Boss6.1% of runs
• Kaiser Crab Boss5.8% of runs
• Knowledge Demon Boss5.4% of runs
• Aeonglass Boss5.0% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.