Melancholy•Skill

Is Melancholy good in Slay the Spire 2?

Melancholy is an uncommon Necrobinder skill in Slay the Spire 2. In combat it resolves as: Gain 13 Block. Reduce this card's cost by Energy whenever ANYONE dies. It currently underperforms most alternatives, sitting at D tier in our Slay the Spire 2 card rankings.

Across 10 recorded runs, decks running it win 11.1% of the time, trailing the 12.6% average by 1.5%. It’s a more selective pick, turning up in just 1.9% of decks that could run it. Necrobinder players keep it in 5.8% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.0 times in the decks that take it.

It performs best next to Right Hand Hand — together they post a +38.9% swing in win rate. It also has strong chemistry with the relic Bag of Preparation, which moves its win rate by +38.9%. At 3 energy, it’s upgraded in 10.0% of runs and usually joins the deck around floor 6.

Upgraded, it gains +4 Block, which is why so many decks invest a rest-site upgrade in it. That’s 1 wins, 8 deaths, and 1 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Queen Boss, which closes out 20.0% of its appearances. Read on for Melancholy’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Necrobinder run.

Best Cards to Pair with Melancholy

Ranked by win-rate lift, Melancholy performs best alongside Right Hand Hand (+38.9%), Cleanse (+38.9%), and Devour Life (+22.2%).

Right Hand Hand+38.9%3 runsCleanse+38.9%3 runsDevour Life+22.2%3 runsClumsy+22.2%3 runsCalcify+22.2%3 runsFetch+22.2%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Melancholy Win Rate by Class

Melancholy is drafted only by the Necrobinder, where it holds a 11.1% win rate across 10 runs.

The Necrobinderappears in 5.8% of its runs (10 tracked)

Best Relics for Melancholy

Melancholy pairs best with the relics Bag of Preparation (+38.9%), Orichalcum (+22.2%), and Bound Phylactery (0.0%), ranked by win-rate lift.

Bag of Preparation+38.9%3 runsOrichalcum+22.2%3 runsBound Phylactery0.0%10 runsLead Paperweight-11.1%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Melancholy Card Details

Melancholy is an uncommon skill costing 3 energy; it’s upgraded in 10.0% of runs and usually picked up by floor 6.

Gain 13 Block. Reduce this card's cost by Energy whenever ANYONE dies.

Upgrade: +4 Block

What Ends Runs with Melancholy

Melancholy’s most common run-enders are Queen Boss (20.0%).

• Queen Boss20.0% of runs

See Also

Compare Melancholy with the rest of the best Slay the Spire 2 cards, relics, and classes below.