Melancholy•Skill

Is Melancholy good in Slay the Spire 2?

Melancholy is an uncommon Necrobinder skill in Slay the Spire 2. In combat it resolves as: Gain 13 Block. Reduce this card's cost by Energy whenever ANYONE dies. It currently underperforms most alternatives, sitting at D tier in our Slay the Spire 2 card rankings.

Across 48 recorded runs, decks running it win 25.5% of the time, comfortably clear of the 19.0% average, by 6.6%. It’s a more selective pick, turning up in just 1.3% of decks that could run it. Necrobinder players keep it in 5.7% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.1 times in the decks that take it.

It performs best next to Delay — together they post a +21.7% swing in win rate. It also has strong chemistry with the relic Anchor, which moves its win rate by +22.0%. At 3 energy, it’s upgraded in 15.7% of runs and usually joins the deck around floor 15.

Upgraded, it gains +4 Block, which is why so many decks invest a rest-site upgrade in it. That’s 12 wins, 35 deaths, and 1 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Phrog Parasite Elite, which closes out 10.4% of its appearances. Read on for Melancholy’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Necrobinder run.

Best Cards to Pair with Melancholy

Ranked by win-rate lift, Melancholy performs best alongside Delay (+21.7%), Friendship (+20.0%), and Grave Warden (+18.4%).

Delay+21.7%6 runsFriendship+20.0%11 runsGrave Warden+18.4%14 runsLethality+18.2%5 runsDirge+18.2%5 runsShroud+16.0%13 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Melancholy Win Rate by Class

Melancholy is played across 2 classes, led by Necrobinder (26.1%) and Silent (0.0%) by win rate.

The Necrobinder26.1%47 runsThe Silent0.0%1 runs

Best Relics for Melancholy

Melancholy pairs best with the relics Anchor (+22.0%), Oddly Smooth Stone (+18.2%), and Stone Cracker (+17.2%), ranked by win-rate lift.

Anchor+22.0%8 runsOddly Smooth Stone+18.2%5 runsStone Cracker+17.2%3 runsTiny Mailbox+17.2%3 runsPotion Belt+17.2%4 runsWhetstone+17.2%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Melancholy Card Details

Melancholy is an uncommon skill costing 3 energy; it’s upgraded in 15.7% of runs and usually picked up by floor 15.

Gain 13 Block. Reduce this card's cost by Energy whenever ANYONE dies.

Upgrade: +4 Block

What Ends Runs with Melancholy

Melancholy’s most common run-enders are Phrog Parasite Elite (10.4%), Knowledge Demon Boss (6.3%), and Test Subject Boss (6.3%).

• Phrog Parasite Elite10.4% of runs
• Knowledge Demon Boss6.3% of runs
• Test Subject Boss6.3% of runs
• Lagavulin Matriarch Boss4.2% of runs
• Infested Prisms Elite4.2% of runs

See Also

Compare Melancholy with the rest of the best Slay the Spire 2 cards, relics, and classes below.