Potion Belt Relic

Is Potion Belt good in Slay the Spire 2?

In Slay the Spire 2, Potion Belt is a common relic you can pick up on your climb. Its effect: Upon pickup, gain potion slots. The data marks it as a weaker relic, settling at D tier — rarely a run-defining grab.

Over 2121 tracked runs the win rate of decks holding it sits at 34.4%, 20.5% ahead of the 13.8% all-run baseline. It sees lighter play, carried in only 10.1% of runs. It does its best work in the hands of the Necrobinder, who post a 38.6% win rate with it. Within Necrobinder runs specifically, it’s carried 11.4% of the time.

Its standout card pairing is Shame, which lifts the relic’s win rate by +45.6% when both are in play. It also works nicely with Beat Down, good for a +40.6% win-rate change. It typically enters the deck near floor 21. As a common relic, how often it’s offered depends on its rarity tier.

Of the runs that carried it, 723 ended in victory while 1382 fell to a defeat. Its most common run-ender is Queen Boss, finishing 5.8% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Potion Belt is worth grabbing.

Pick or Skip: Potion Belt

Players take Potion Belt in 63.4% of the 3355 offers it appears in; those runs win 34.4% against 27.3% for runs that passed, a pick lift of +7.0% over 2104 decided runs.

Taken 2127 times out of 3355 offers.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

Best Cards with Potion Belt

The cards that gain the most from carrying Potion Belt are Shame (+45.6%), Beat Down (+40.6%), and Flanking (+36.6%), each shown with its win-rate swing.

Shame+45.6%15 runsBeat Down+40.6%21 runsFlanking+36.6%31 runsSecret Weapon+36.2%18 runsAutomation+35.1%37 runsBundle of Joy+34.6%29 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Potion Belt Win Rate by Class

Of the 5 classes that carry Potion Belt, it performs best with Necrobinder (38.6%), Silent (38.4%), and Regent (36.0%).

The Necrobinder38.6%415 runsThe Silent38.4%455 runsThe Regent36.0%335 runsThe Ironclad32.6%497 runsThe Defect25.5%402 runs

Potion Belt Details

Carried in 10.1% of runs, Potion Belt is a common relic typically acquired near floor 21.

Upon pickup, gain potion slots.

What Ends Runs with Potion Belt

Runs carrying Potion Belt end most often against Queen Boss (5.8%), Test Subject Boss (5.7%), and Aeonglass Boss (5.0%) — the share of its runs each accounts for is shown.

• Queen Boss5.8% of runs
• Test Subject Boss5.7% of runs
• Aeonglass Boss5.0% of runs
• Knowledge Demon Boss4.5% of runs
• Kaiser Crab Boss4.0% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.