
PutrefySkill
Apply Weak. Apply Vulnerable.
Is Putrefy good in Slay the Spire 2?
In Slay the Spire 2, Putrefy is an uncommon skill from the Necrobinder card pool. Its effect: Apply Weak. Apply Vulnerable. Performance-wise it’s a solid if unspectacular include, rated C tier overall.
Over 218 tracked runs its win rate sits at 27.9%, 13.8% ahead of the 14.1% all-deck baseline. It sees niche play, included in only 2.1% of eligible runs. When it is actually offered players take it 28.3% of the time, and that looks correct: those runs win 28.9% against 25.7% for runs that passed, a +3.0% pick lift over 180 decided runs. Within Necrobinder runs it’s drafted 11.3% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.1 copies on average.
Its standout pairing so far is Neurosurge, which lifts its win rate by +24.1% when the two share a deck. On the relic side, Tiny Mailbox is its standout companion, worth a +29.0% win-rate swing alongside it. It costs 1 energy, gets upgraded 29.4% of the time, and tends to be picked up near floor 15.
Of the runs that drafted it, 60 ended in victory against 155 deaths and 3 abandons. Its most common run-ender is Decimillipede Elite, finishing 5.5% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Putrefy fits a Necrobinder deck.
Putrefy Win Rate & Pick Rate
At a 27.9% win rate, Putrefy runs 13.8% ahead of the 14.1% all-deck baseline — the bars below put the two side by side.
Run Outcomes with Putrefy
Across the 218 tracked runs that drafted Putrefy, 60 ended in a win and 158 in a loss — a 27.5% win share, counting abandons as losses.
- Wins 27.5%
- Losses 72.5%
Pick or Skip: Putrefy
Players take Putrefy in 28.3% of the 688 offers it appears in; those runs win 28.9% against 25.7% for runs that passed, a pick lift of +3.0% over 180 decided runs.
Taken 195 times out of 688 offers.
Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.
Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.
When to Pick Up Putrefy
Of the 4 pickup windows recorded for Putrefy, Act 3 is the best: 56.5% across 23 runs.
Win rate of runs by the act Putrefy entered the deck. Acts that have not reached the sample floor show their run count only.
Best Cards to Pair with Putrefy
Putrefy’s strongest card pairings so far are Neurosurge (+24.1%), Hang (+23.2%), and Misery (+19.5%), each shown with the win-rate lift it adds.
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Putrefy Win Rate by Class
Exclusive to the Necrobinder, Putrefy posts a 28.4% win rate over 214 tracked runs.
Best Relics for Putrefy
The relics that swing Putrefy’s win rate the most are Tiny Mailbox (+29.0%), Bag of Preparation (+22.9%), and Bronze Scales (+21.5%), with each lift shown.
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Putrefy Card Details
A 1-energy uncommon skill, Putrefy is upgraded 29.4% of the time and tends to enter the deck around floor 15.
Apply Weak. Apply Vulnerable.
What Ends Runs with Putrefy
Runs holding Putrefy end most often against Decimillipede Elite (5.5%), Test Subject Boss (5.0%), and Aeonglass Boss (4.6%) — the share of its runs each accounts for is shown.
- Decimillipede Elite5.5% of runs
- Test Subject Boss5.0% of runs
- Aeonglass Boss4.6% of runs
- Infested Prisms Elite4.1% of runs
- Kaiser Crab Boss4.1% of runs
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Putrefy – Frequently Asked Questions
Is Putrefy good in Slay the Spire 2?
Across 218 tracked runs, Putrefy has a 27.9% win rate — +13.8% above the average deck. Win rate reflects how often runs that include the card end in victory.
What does Putrefy do in Slay the Spire 2?
Putrefy costs 1 energy. Apply Weak. Apply Vulnerable.
What class is Putrefy in Slay the Spire 2?
Putrefy is an Uncommon Necrobinder Skill.
Is Putrefy worth upgrading in Slay the Spire 2?
Putrefy can be upgraded at a rest site to improve its effect.
What is the best relic for Putrefy?
In tracked runs, Putrefy has performed best alongside Tiny Mailbox, which lifts its win rate by +29.0% over 16 runs together.
Should I take Putrefy when it is offered?
Players take Putrefy in 28.3% of its 688 recorded offers. Runs that picked it win 28.9% (180 decided runs) against 25.7% for runs that skipped it (354 decided runs) — a +3.2% difference, and a +3.0% pick lift once sample size is accounted for.
See Also
Keep exploring Slay the Spire 2 tier lists and stats below.