Fragrant Mushroom•Relic

Is Fragrant Mushroom good in Slay the Spire 2?

Fragrant Mushroom is an event relic in Slay the Spire 2. While carried, it does the following: Upon pickup, lose HP and Upgrade random cards. It ranks among the better relics in the game right now, earning a spot at S tier in our Slay the Spire 2 relic tier list.

Across 114 recorded runs, decks carrying it win 62.2% of the time, comfortably clear of the 18.9% average, by 43.2%. It’s a more situational relic, showing up in just 3.0% of runs. The class that gets the most out of it is the Necrobinder, at a 69.2% win rate. Necrobinder players hold onto it in 3.1% of their runs.

It combos especially well with Afterlife, worth a +37.8% win-rate swing together. Another strong card to run with it is Bury, worth +37.8% to its win rate. On average it’s acquired around floor 39 of a run. Its event rarity shapes how frequently you’ll run into it.

It has 69 run wins against 42 losses in our tracked data. When runs carrying it end, the most frequent culprit is Test Subject Boss, which closes out 13.2% of them. Read on for Fragrant Mushroom’s complete card, class, and threat breakdown before you decide to pick it up.

Best Cards with Fragrant Mushroom

Ranked by win-rate lift, the best cards to run with Fragrant Mushroom are Afterlife (+37.8%), Bury (+37.8%), and Dirge (+37.8%).

Afterlife+37.8%6 runsBury+37.8%4 runsDirge+37.8%7 runsDrain Power+37.8%6 runsPull Aggro+37.8%3 runsSeven Stars+37.8%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Fragrant Mushroom Win Rate by Class

Fragrant Mushroom shows up across 5 classes, led by Necrobinder (69.2%), Silent (69.0%), and Ironclad (57.1%) by win rate.

The Necrobinder69.2%26 runsThe Silent69.0%29 runsThe Ironclad57.1%22 runsThe Regent56.3%16 runsThe Defect52.6%21 runs

Fragrant Mushroom Details

Fragrant Mushroom is an event relic carried in 3.0% of runs and usually picked up around floor 39.

Upon pickup, lose HP and Upgrade random cards.

What Ends Runs with Fragrant Mushroom

Fragrant Mushroom’s most common run-enders are Test Subject Boss (13.2%), Queen Boss (7.9%), and Doormaker Boss (4.4%).

• Test Subject Boss13.2% of runs
• Queen Boss7.9% of runs
• Doormaker Boss4.4% of runs
• Aeonglass Boss4.4% of runs
• Fabricator Normal1.8% of runs

See Also

Compare Fragrant Mushroom with the rest of the best Slay the Spire 2 relics, cards, and classes below.