
Seraphinevs Annie
Seraphine vs Annie is a decisive matchup in LoL patch 26.11. Seraphine wins with a 63.6% win rate (+27.3%) over Annie based on 22 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Annie matchup.
Seraphine Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Seraphine vs Annie Matchup?

Seraphine vs Annie Matchup Summary
The Seraphine vs Annie matchup is a decisive matchup in League of Legends ranked play. Based on 22 recent matches analyzed, Seraphine wins with a 63.6% win rate compared to Annie's 36.4%, giving Seraphine a 27.3 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Annie players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Annie leads by 262 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine players can confidently pick into Annie and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Annie away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Seraphine vs Annie Laning Phase Breakdown
Annie is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Annie holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Seraphine Build Against Annie
Ionian Boots of Lucidity is the optimal boots choice against Annie, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Annie are Cryptbloom, Malignance and Seraph's Embrace. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Annie. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Annie matchup.
Early Game vs Late Game
Seraphine dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Annie. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Seraphine is far superior in the late game (25+ minutes), boasting a 64.7% win rate — 29.4 points above Annie. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.
Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Annie players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Seraphine Runes Against Annie
Running Sorcery primary with Resolve secondary allows Seraphine to press their advantage against Annie, amplifying the strengths that make this a favorable matchup.
Seraphine matchup data for League of Legends patch 26.11. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 47.75% | 779 | 1.7 | 466 | 9,359 | 44.9% | 49.5% | |
| 50.91% | 550 | 1.4 | 493 | 9,173 | 58.0% | 45.0% | |
| 49.45% | 548 | 1.4 | 487 | 9,007 | 51.2% | 48.0% | |
| 50.83% | 543 | 1.4 | 487 | 9,197 | 46.8% | 53.9% | |
| 52.69% | 501 | 1.5 | 497 | 9,352 | 48.8% | 55.5% | |
| 50.21% | 478 | 1.8 | 526 | 9,255 | 51.6% | 49.0% | |
| 48.69% | 421 | 1.5 | 470 | 9,012 | 49.2% | 48.3% | |
| 50.00% | 334 | 1.4 | 453 | 9,010 | 50.4% | 49.7% | |
| 50.91% | 330 | 1.9 | 524 | 9,715 | 53.4% | 49.2% | |
| 51.72% | 319 | 1.4 | 469 | 9,560 | 46.7% | 55.4% | |
| 52.44% | 307 | 1.4 | 493 | 8,930 | 52.7% | 52.2% | |
| 53.17% | 284 | 1.7 | 483 | 9,531 | 47.7% | 56.6% | |
| 52.84% | 282 | 1.4 | 487 | 8,901 | 49.2% | 55.8% | |
| 50.78% | 258 | 1.5 | 444 | 9,247 | 50.5% | 51.0% | |
| 47.97% | 246 | 1.5 | 466 | 9,327 | 44.7% | 50.4% | |
| 54.85% | 237 | 1.8 | 584 | 9,764 | 54.8% | 54.9% | |
| 54.85% | 237 | 1.4 | 452 | 8,965 | 51.9% | 57.4% | |
| 53.07% | 228 | 1.5 | 391 | 8,663 | 58.8% | 46.8% | |
| 54.63% | 227 | 1.8 | 498 | 9,664 | 55.6% | 54.0% | |
| 43.13% | 211 | 1.3 | 502 | 8,901 | 35.6% | 48.8% | |
| 52.22% | 203 | 1.4 | 522 | 9,037 | 58.4% | 47.4% | |
| 43.22% | 199 | 1.5 | 498 | 8,961 | 47.1% | 40.4% | |
| 48.44% | 192 | 1.4 | 497 | 9,418 | 51.2% | 46.3% | |
| 53.45% | 174 | 1.8 | 462 | 9,232 | 49.4% | 56.7% | |
| 49.70% | 169 | 1.6 | 614 | 9,703 | 44.4% | 52.2% | |
| 52.26% | 155 | 1.4 | 479 | 9,118 | 56.9% | 48.2% | |
| 57.53% | 146 | 1.4 | 569 | 9,690 | 67.9% | 51.1% | |
| 54.48% | 145 | 4.5 | 662 | 11,521 | 62.3% | 50.0% | |
| 52.52% | 139 | 1.4 | 489 | 9,051 | 64.1% | 42.7% | |
| 61.29% | 124 | 1.6 | 481 | 9,075 | 67.7% | 54.8% | |
| 50.00% | 122 | 1.4 | 462 | 8,512 | 50.8% | 49.1% | |
| 50.00% | 120 | 1.4 | 508 | 9,232 | 52.8% | 47.8% | |
| 51.30% | 115 | 1.4 | 463 | 8,905 | 42.2% | 57.1% | |
| 59.13% | 115 | 6.2 | 814 | 12,230 | 54.7% | 62.9% | |
| 53.49% | 86 | 1.5 | 480 | 9,035 | 67.5% | 41.3% | |
| 54.88% | 82 | 5.8 | 677 | 11,898 | 60.0% | 51.9% | |
| 61.25% | 80 | 4.8 | 789 | 12,002 | 75.9% | 52.9% | |
| 56.76% | 74 | 6.8 | 807 | 12,478 | 63.9% | 50.0% | |
| 53.42% | 73 | 2.0 | 510 | 9,991 | 52.0% | 54.2% | |
| 56.16% | 73 | 1.5 | 514 | 9,449 | 56.8% | 55.6% | |
| 46.88% | 64 | 1.5 | 467 | 9,510 | 52.0% | 43.6% | |
| 43.33% | 60 | 1.6 | 557 | 9,121 | 60.7% | 28.1% | |
| 48.33% | 60 | 2.1 | 440 | 8,595 | 48.3% | 48.4% | |
| 54.24% | 59 | 6.2 | 831 | 12,840 | 42.1% | 60.0% | |
| 54.24% | 59 | 3.3 | 592 | 10,058 | 60.9% | 50.0% | |
| 60.34% | 58 | 5.3 | 751 | 11,906 | 51.9% | 67.7% | |
| 63.16% | 57 | 2.0 | 567 | 10,732 | 79.0% | 55.3% | |
| 44.23% | 52 | 1.7 | 575 | 9,420 | 52.0% | 37.0% | |
| 51.06% | 47 | 2.0 | 462 | 9,108 | 47.6% | 53.9% | |
| 50.00% | 40 | 2.2 | 608 | 10,026 | 52.6% | 47.6% | |
| 56.76% | 37 | 6.3 | 891 | 12,395 | 62.5% | 52.4% | |
| 44.44% | 36 | 2.5 | 515 | 9,087 | 30.8% | 52.2% | |
| 60.61% | 33 | 4.2 | 598 | 11,534 | 55.6% | 62.5% | |
| 51.52% | 33 | 5.3 | 666 | 11,600 | 61.5% | 45.0% | |
| 42.42% | 33 | 6.2 | 813 | 10,735 | 42.1% | 42.9% | |
| 51.52% | 33 | 6.8 | 787 | 11,426 | 58.8% | 43.8% | |
| 65.63% | 32 | 1.6 | 474 | 9,163 | 73.3% | 58.8% | |
| 65.63% | 32 | 4.1 | 681 | 10,156 | 66.7% | 64.7% | |
| 58.06% | 31 | 1.6 | 485 | 9,799 | 66.7% | 52.6% | |
| 56.67% | 30 | 6.6 | 733 | 10,933 | 62.5% | 50.0% | |
| 41.38% | 29 | 1.4 | 501 | 9,366 | 30.8% | 50.0% | |
| 44.44% | 27 | 5.1 | 677 | 10,722 | 63.6% | 31.3% | |
| 62.96% | 27 | 1.6 | 498 | 10,328 | 62.5% | 63.2% | |
| 54.17% | 24 | 4.2 | 624 | 9,656 | 45.5% | 61.5% | |
| 50.00% | 22 | 2.4 | 567 | 9,749 | 40.0% | 58.3% | |
| 45.45% | 22 | 3.0 | 490 | 9,418 | 25.0% | 57.1% | |
| 63.64% | 22 | 2.2 | 508 | 11,567 | 60.0% | 64.7% | |
| 40.00% | 20 | 6.5 | 801 | 13,556 | 33.3% | 41.2% | |
| 55.00% | 20 | 6.7 | 792 | 12,479 | 66.7% | 45.5% | |
| 55.00% | 20 | 2.0 | 462 | 9,458 | 57.1% | 53.9% | |
| 45.00% | 20 | 5.8 | 714 | 11,072 | 40.0% | 50.0% | |
| 70.00% | 20 | 1.4 | 645 | 10,698 | 87.5% | 58.3% | |
| 63.16% | 19 | 1.4 | 434 | 10,160 | 60.0% | 64.3% | |
| 61.11% | 18 | 5.6 | 703 | 8,059 | 64.3% | 50.0% | |
| 58.82% | 17 | 6.2 | 865 | 12,026 | 50.0% | 63.6% | |
| 35.29% | 17 | 1.2 | 446 | 10,237 | 75.0% | 23.1% | |
| 75.00% | 16 | 6.7 | 918 | 13,627 | 71.4% | 77.8% | |
| 37.50% | 16 | 1.5 | 479 | 8,928 | 40.0% | 36.4% | |
| 60.00% | 15 | 6.7 | 761 | 12,988 | 66.7% | 55.6% | |
| 40.00% | 15 | 5.3 | 597 | 10,546 | 33.3% | 44.4% | |
| 60.00% | 15 | 1.6 | 463 | 10,507 | 75.0% | 54.5% | |
| 50.00% | 14 | 3.2 | 647 | 10,328 | 50.0% | 50.0% | |
| 50.00% | 14 | 2.6 | 551 | 9,742 | 50.0% | 50.0% | |
| 42.86% | 14 | 4.8 | 584 | 9,774 | 50.0% | 37.5% | |
| 53.85% | 13 | 6.3 | 921 | 12,200 | 66.7% | 42.9% | |
| 30.77% | 13 | 4.1 | 603 | 9,877 | 33.3% | 28.6% | |
| 61.54% | 13 | 3.1 | 594 | 9,468 | 42.9% | 83.3% | |
| 58.33% | 12 | 6.7 | 825 | 9,196 | 70.0% | 0.0% | |
| 50.00% | 12 | 4.3 | 666 | 9,424 | 33.3% | 66.7% | |
| 58.33% | 12 | 6.0 | 764 | 11,191 | 60.0% | 57.1% | |
| 72.73% | 11 | 6.1 | 758 | 11,907 | 100.0% | 66.7% | |
| 27.27% | 11 | 4.5 | 549 | 9,363 | 0.0% | 50.0% | |
| 54.55% | 11 | 6.2 | 660 | 11,060 | 50.0% | 60.0% | |
| 60.00% | 10 | 5.6 | 803 | 11,242 | 50.0% | 75.0% | |
| 80.00% | 10 | 1.4 | 477 | 7,161 | 87.5% | 50.0% | |
| 66.67% | 9 | 4.5 | 521 | 10,244 | 100.0% | 62.5% | |
| 44.44% | 9 | 1.8 | 423 | 8,693 | 66.7% | 33.3% | |
| 37.50% | 8 | 6.2 | 930 | 11,957 | 40.0% | 33.3% | |
| 62.50% | 8 | 1.6 | 623 | 9,742 | 33.3% | 80.0% | |
| 37.50% | 8 | 1.5 | 395 | 8,010 | 25.0% | 50.0% | |
| 37.50% | 8 | 1.3 | 467 | 9,596 | 25.0% | 50.0% | |
| 25.00% | 8 | 5.3 | 670 | 10,068 | 50.0% | 16.7% | |
| 25.00% | 8 | 3.4 | 577 | 9,673 | 25.0% | 25.0% | |
| 62.50% | 8 | 1.4 | 570 | 11,774 | 0.0% | 71.4% | |
| 75.00% | 8 | 5.4 | 707 | 11,288 | 50.0% | 83.3% | |
| 50.00% | 8 | 1.1 | 463 | 8,690 | 50.0% | 50.0% | |
| 50.00% | 8 | 6.2 | 987 | 13,253 | 66.7% | 40.0% | |
| 75.00% | 8 | 1.6 | 487 | 10,735 | 50.0% | 83.3% | |
| 85.71% | 7 | 1.4 | 537 | 8,417 | 100.0% | 0.0% | |
| 42.86% | 7 | 1.9 | 492 | 10,031 | 33.3% | 50.0% | |
| 71.43% | 7 | 3.1 | 635 | 10,657 | 100.0% | 60.0% | |
| 57.14% | 7 | 3.4 | 739 | 12,184 | 100.0% | 50.0% | |
| 100.00% | 7 | 3.1 | 595 | 7,466 | 100.0% | 100.0% | |
| 71.43% | 7 | 3.0 | 520 | 8,011 | 75.0% | 66.7% | |
| 33.33% | 6 | 7.3 | 822 | 10,976 | 25.0% | 50.0% | |
| 100.00% | 6 | 2.3 | 548 | 9,903 | 100.0% | 100.0% | |
| 83.33% | 6 | 2.2 | 474 | 10,918 | 100.0% | 80.0% | |
| 50.00% | 6 | 1.6 | 382 | 9,863 | 50.0% | 50.0% | |
| 100.00% | 5 | 5.9 | 570 | 11,549 | 0.0% | 100.0% | |
| 40.00% | 5 | 1.6 | 496 | 10,447 | 50.0% | 33.3% | |
| 60.00% | 5 | 1.2 | 565 | 10,300 | 0.0% | 75.0% | |
| 40.00% | 5 | 6.0 | 646 | 9,774 | 25.0% | 100.0% | |
| 40.00% | 5 | 3.8 | 646 | 10,549 | 66.7% | 0.0% | |
| 80.00% | 5 | 1.5 | 499 | 10,155 | 50.0% | 100.0% | |
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Seraphine vs Annie - Frequently Asked Questions
How does Seraphine do against Annie in League of Legends?
Seraphine wins the Seraphine vs Annie matchup with a 63.6% win rate compared to Annie's 36.4%, a 27.3 percentage point difference. This data is based on 22 recent ranked games in patch 26.11.
How does Seraphine do against Annie in the early game?
In the early game, Seraphine has the advantage against Annie with a 60.0% win rate versus 40.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Seraphine do against Annie in the late game?
In the late game, Seraphine takes over the Seraphine vs Annie matchup with a 64.7% win rate compared to 35.3%. Seraphine scales better into team fights and objective contests after 25 minutes.
Who wins the Seraphine vs Annie matchup?
Seraphine wins the matchup against Annie with a 63.6% win rate in League of Legends patch 26.11. The 27.3 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 22 games analyzed.
What is the best Seraphine build against Annie?
The best Seraphine build against Annie includes Cryptbloom, Malignance, Seraph's Embrace with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Seraphine runes against Annie?
The best Seraphine runes against Annie use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Seraphine vs Annie matchup. See the full rune breakdown in the matchup comparison above.
Does Seraphine counter Annie?
Yes, Seraphine has a favorable matchup against Annie with a 63.6% win rate. Seraphine strongly counters Annie in lane based on current patch 26.11 data.
How do I play Seraphine against Annie?
When playing Seraphine against Annie, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
