Illaoi - League of Legends Champion
Win Rate
54.4%
Pick Rate
2.4%

Illaoivs Vayne

SFighterTank
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 6, 2026
MethodologyData Methodology

Illaoi vs Vayne is a decisive matchup in LoL patch 26.11. Vayne wins with a 53.3% win rate (+6.7%) over Illaoi based on 30 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Illaoi build, runes, laning stats, and strategies for the Illaoi vs Vayne matchup.

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Illaoi Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Illaoi performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Illaoi - 46.7% win rate in this matchup
Illaoi
46.7% WR
VS
Vayne vs Illaoi matchup - 53.3% win rate
Vayne
53.3% WR

Who Wins the Illaoi vs Vayne Matchup?

Vayne wins the Illaoi vs Vayne matchup
Winner
Vayne
Matches: 30
46.7%
Win Rate
53.3%
6.1
CS / min
5.6
768
DMG / min
855
11,764
Gold / game
12,152
310
Heal / min
231
1,407
DMG Mitigated / min
524
0.3
CC / min
0.4
44.4%
Early Game WR
55.6%
47.6%
Late Game WR
52.4%

Illaoi vs Vayne Matchup Summary

The Illaoi vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 30 recent matches analyzed, Vayne wins with a 53.3% win rate compared to Illaoi's 46.7%, giving Vayne a 6.7 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Illaoi players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Illaoi leads by 962 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Illaoi players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Illaoi vs Vayne Laning Phase Breakdown

Vayne wins the laning phase against Illaoi in League of Legends

Vayne is favored during the laning phase against Illaoi, winning 3 out of 5 key stat categories. Vayne holds advantages in damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.1Illaoi
5.6Vayne
Illaoi edges out Vayne by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Illaoi.
Damage
768Illaoi
855Vayne
Vayne heavily out-damages Illaoi by 87 DMG/min, dominating both short trades and all-in fights. Illaoi should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
11,764Illaoi
12,152Vayne
Vayne earns 389 more gold per game than Illaoi, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
0.3Illaoi
0.4Vayne
Both Illaoi and Vayne provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
1,717Illaoi
755Vayne
Illaoi vastly out-sustains Vayne, healing and mitigating 962 more damage per minute. This massive durability gap means Illaoi can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Illaoi Build Against Vayne

Mercury's Treads is the optimal boots choice against Vayne, providing the mobility and stats Illaoi needs most in this matchup. The top-performing core items for Illaoi against Vayne are Iceborn Gauntlet, Thornmail and Black Cleaver. This combination gives Illaoi an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 75.0% win rate across 4 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Illaoi vs Vayne matchup.

Early Game vs Late Game

Early Game
Vayne
55.6%
+11.1% advantage
Illaoi early game win rateIllaoi44.4%
Vayne early game win rateVayne55.6%
Late Game
Vayne
52.4%
+4.8% advantage
Illaoi late game win rateIllaoi47.6%
Vayne late game win rateVayne52.4%

Vayne dominates the early game (first 15 minutes) with a commanding 55.6% win rate — a 11.1 percentage point lead over Illaoi. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

In the late game (25+ minutes), Vayne takes over with a 52.4% win rate, leading Illaoi by 4.8 percentage points. Vayne scales more effectively into team fights and objective contests.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Illaoi players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Illaoi Runes Against Vayne

Precision rune tree - Illaoi primary runes vs VaynePrecision
Conqueror - best Illaoi rune vs VaynePresence of Mind - best Illaoi rune vs VayneLegend: Haste - best Illaoi rune vs VayneLast Stand - best Illaoi rune vs Vayne
Resolve rune tree - Illaoi secondary runes vs VayneResolve
Revitalize - best Illaoi rune vs VayneDemolish - best Illaoi rune vs Vayne
100.0% WR

The Precision and Resolve rune setup gives Illaoi the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Illaoi matchup data for League of Legends patch 26.11. The table below shows Illaoi's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Illaoi build, runes, laning stats, and early vs late game analysis for that specific matchup.

Illaoi matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.99%1837.298912,05252.0%43.4%
42.35%1706.387811,02538.7%45.3%
43.98%1666.777611,17644.9%43.3%
52.87%1576.694311,75263.2%44.9%
46.15%1436.987211,22447.5%45.2%
53.49%1297.01,16012,13856.1%50.8%
63.00%1007.398312,54367.5%60.0%
47.42%977.094612,16352.5%43.9%
56.84%957.51,25312,67063.8%50.0%
48.39%937.31,25912,34452.5%45.3%
53.26%926.799411,33557.1%48.8%
62.22%907.11,04012,53267.6%58.5%
45.35%867.41,41512,13851.2%40.0%
48.81%846.81,00311,59143.8%51.9%
44.44%816.885511,83560.0%35.3%
56.58%767.41,16212,30464.1%48.6%
57.35%687.01,13813,18566.7%51.2%
55.22%677.01,02512,63460.0%51.4%
75.00%646.81,07712,00075.0%75.0%
42.86%637.41,20311,46551.7%35.3%
41.27%636.371911,63633.3%44.4%
52.46%616.998111,84245.8%56.8%
50.00%607.31,06912,27951.5%48.1%
60.34%587.41,23113,24768.2%55.6%
60.00%557.595213,62375.0%51.4%
52.94%516.995712,74242.1%59.4%
59.18%497.01,05612,26863.6%55.6%
50.00%487.11,00612,55757.1%44.4%
60.42%486.81,21212,64072.2%53.3%
43.75%486.797912,37244.4%43.3%
54.17%486.989612,79364.7%48.4%
66.67%457.31,24012,60863.6%69.6%
64.44%457.11,01112,53675.0%58.6%
40.00%456.81,01611,74341.2%39.3%
39.53%437.597911,32440.9%38.1%
63.41%417.71,30413,52165.4%60.0%
71.79%396.91,07312,13268.4%75.0%
59.38%327.21,04713,33177.8%52.2%
60.00%306.81,14612,08258.3%61.1%
46.67%306.176811,76444.4%47.6%
58.62%297.41,23913,57975.0%47.1%
62.07%297.31,08412,41864.3%60.0%
66.67%277.699512,78884.6%50.0%
65.38%267.099212,72580.0%56.3%
48.00%257.397614,02350.0%47.4%
54.17%246.695412,60833.3%66.7%
38.10%216.993810,94150.0%30.8%
47.62%217.31,01412,50820.0%56.3%
38.10%216.785410,90955.6%25.0%
68.42%196.793911,08090.9%37.5%
44.44%186.678010,95514.3%63.6%
50.00%186.888712,91260.0%46.1%
72.22%186.91,18613,02366.7%83.3%
60.00%156.71,03912,89766.7%58.3%
33.33%157.079112,85733.3%33.3%
15.38%135.69769,4020.0%28.6%
30.77%136.588912,39716.7%42.9%
30.77%137.598014,27733.3%30.0%
75.00%126.91,20012,70566.7%83.3%
27.27%116.91,20111,03228.6%25.0%
40.00%106.895613,49166.7%28.6%
30.00%106.587211,55425.0%33.3%
50.00%106.897212,02675.0%33.3%
50.00%106.368911,65633.3%57.1%
50.00%106.792110,60966.7%25.0%
55.56%96.81,1029,54575.0%40.0%
55.56%97.881310,681100.0%0.0%
77.78%96.31,29314,298100.0%71.4%
66.67%97.085711,60360.0%75.0%
50.00%84.568610,61925.0%75.0%
42.86%77.41,19912,27960.0%0.0%
57.14%76.61,17613,01075.0%33.3%
42.86%77.77118,14540.0%50.0%
57.14%77.485713,66550.0%60.0%
28.57%74.870811,3910.0%33.3%
42.86%77.81,24716,127100.0%33.3%
66.67%67.38509,88750.0%100.0%
50.00%67.193411,927100.0%0.0%
83.33%66.11,11813,69550.0%100.0%
40.00%56.06229,40940.0%0.0%
60.00%58.59706,53675.0%0.0%
60.00%56.81,20611,1420.0%75.0%
80.00%55.681010,46166.7%100.0%
60.00%54.59299,211100.0%33.3%

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Illaoi vs Vayne - Frequently Asked Questions

How does Illaoi do against Vayne in League of Legends?

Vayne wins the Illaoi vs Vayne matchup with a 53.3% win rate compared to Illaoi's 46.7%, a 6.7 percentage point difference. This data is based on 30 recent ranked games in patch 26.11.

How does Illaoi do against Vayne in the early game?

In the early game, Vayne has the advantage against Illaoi with a 55.6% win rate versus 44.4%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Illaoi do against Vayne in the late game?

In the late game, Vayne takes over the Illaoi vs Vayne matchup with a 52.4% win rate compared to 47.6%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Illaoi vs Vayne matchup?

Vayne wins the matchup against Illaoi with a 53.3% win rate in League of Legends patch 26.11. The 6.7 percentage point advantage means Vayne is significantly favored in this lane matchup based on 30 games analyzed.

What is the best Illaoi build against Vayne?

The best Illaoi build against Vayne includes Iceborn Gauntlet, Thornmail, Black Cleaver with Mercury's Treads. This build achieves a 75.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Illaoi runes against Vayne?

The best Illaoi runes against Vayne use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Illaoi vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Illaoi counter Vayne?

No, Illaoi struggles against Vayne with only a 46.7% win rate. Vayne has the advantage in this matchup. Illaoi players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.

How do I play Illaoi against Vayne?

When playing Illaoi against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.