Lissandra - League of Legends Champion
Win Rate
51.3%
Pick Rate
2.2%

Lissandravs Karma

AMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 19, 2026
MethodologyData Methodology

Lissandra vs Karma is a decisive matchup in LoL patch 26.7. Lissandra wins with a 80.0% win rate (+60.0%) over Karma based on 5 games. Lissandra holds the advantage in both the early and late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Karma matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karma - 80.0% win rateKarma(80.0%)
Lissandra - 80.0% win rate in this matchup
Lissandra
80.0% WR
VS
Karma vs Lissandra matchup - 20.0% win rate
Karma
20.0% WR

Who Wins the Lissandra vs Karma Matchup?

Lissandra wins the Lissandra vs Karma matchup
Winner
Lissandra
Matches: 5
80.0%
Win Rate
20.0%
5.0
CS / min
3.8
647
DMG / min
572
12,918
Gold / game
11,437
156
Heal / min
286
460
DMG Mitigated / min
683
1.6
CC / min
1.1
50.0%
Early Game WR
50.0%
100.0%
Late Game WR
0.0%

Lissandra vs Karma Matchup Summary

The Lissandra vs Karma matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Lissandra wins with a 80.0% win rate compared to Karma's 20.0%, giving Lissandra a 60.0 percentage point advantage. Lissandra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Karma players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Karma leads by 352 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Karma and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Karma away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Karma Laning Phase Breakdown

Lissandra wins the laning phase against Karma in League of Legends

Lissandra is favored during the laning phase against Karma, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
5.0Lissandra
3.8Karma
Lissandra significantly out-farms Karma by 1.2 CS per minute, accumulating an estimated 18 CS lead by mid game. This substantial farming gap gives Lissandra a major gold advantage and earlier item completions. Karma players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
647Lissandra
572Karma
Lissandra deals 75 more champion damage per minute than Karma. While noticeable in extended trades, this gap can be offset by Karma choosing favorable fight windows, such as engaging when Lissandra's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
12,918Lissandra
11,437Karma
Lissandra generates a commanding 1,481 more gold per game than Karma. This substantial economic advantage means Lissandra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karma should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.6Lissandra
1.1Karma
Lissandra provides 0.5 seconds more crowd control per minute than Karma, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
616Lissandra
968Karma
Karma vastly out-sustains Lissandra, healing and mitigating 352 more damage per minute. This massive durability gap means Karma can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lissandra Build Against Karma

Sorcerer's Shoes is the optimal boots choice against Karma, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Karma are Jak'Sho, The Protean, Zhonya's Hourglass and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Karma. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Karma matchup.

Early Game vs Late Game

Early Game
Lissandra
50.0%
+0.0% advantage
Lissandra early game win rateLissandra50.0%
Karma early game win rateKarma50.0%
Late Game
Lissandra
100.0%
+100.0% advantage
Lissandra late game win rateLissandra100.0%
Karma late game win rateKarma0.0%

The early game (first 15 minutes) is a toss-up between Lissandra and Karma, with Lissandra holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Lissandra is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Karma. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

Lissandra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Karma players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Lissandra Runes Against Karma

Resolve rune tree - Lissandra primary runes vs KarmaResolve
Aftershock - best Lissandra rune vs KarmaFont of Life - best Lissandra rune vs KarmaBone Plating - best Lissandra rune vs KarmaOvergrowth - best Lissandra rune vs Karma
Sorcery rune tree - Lissandra secondary runes vs KarmaSorcery
Manaflow Band - best Lissandra rune vs KarmaScorch - best Lissandra rune vs Karma
100.0% WR

Running Resolve primary with Sorcery secondary allows Lissandra to press their advantage against Karma, amplifying the strengths that make this a favorable matchup.


Lissandra matchup data for League of Legends patch 26.7. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
60.00%1306.883712,37853.6%64.9%
57.52%1136.882011,83565.2%52.2%
50.00%766.890711,85747.2%52.5%
45.95%746.778211,93537.5%52.4%
47.95%736.982512,39648.3%47.7%
52.11%717.081212,61135.7%62.8%
53.62%696.788911,32658.1%50.0%
54.55%666.798912,99555.2%54.0%
50.00%626.990112,04736.7%62.5%
54.10%616.687711,06545.5%64.3%
57.38%616.276711,40053.6%60.6%
34.48%586.766810,83031.4%39.1%
40.00%556.372811,33333.3%45.2%
46.94%496.975711,65340.0%51.7%
50.00%486.776511,97850.0%50.0%
50.00%406.476411,31941.2%56.5%
65.00%407.283311,56863.6%66.7%
56.41%397.084511,79244.4%66.7%
60.00%356.876110,99150.0%70.6%
48.57%356.881511,55440.0%55.0%
36.36%336.784111,39846.7%27.8%
21.21%336.478711,43923.1%20.0%
63.33%307.380811,58476.5%46.1%
62.07%297.188313,06883.3%47.1%
58.62%296.596211,72763.6%55.6%
53.57%286.983410,91262.5%41.7%
46.43%286.68679,78147.1%45.5%
53.57%286.881411,53950.0%56.3%
59.26%277.079712,15157.1%61.5%
69.23%266.586913,22971.4%68.4%
57.69%266.679612,06775.0%42.9%
40.00%257.276711,82854.5%28.6%
64.00%256.680511,12450.0%73.3%
41.67%246.992712,63340.0%42.9%
66.67%247.178811,24454.5%76.9%
73.68%197.196712,77550.0%90.9%
44.44%187.31,06512,47460.0%25.0%
64.71%177.290311,48980.0%42.9%
33.33%156.473710,70622.2%50.0%
57.14%146.289412,26342.9%71.4%
42.86%147.375110,43150.0%25.0%
76.92%136.783113,11175.0%77.8%
38.46%136.082212,47860.0%25.0%
30.77%136.896711,40720.0%37.5%
15.38%136.584811,09216.7%14.3%
45.45%116.480812,11440.0%50.0%
27.27%116.792811,21620.0%33.3%
54.55%116.888611,95450.0%57.1%
40.00%106.882512,83166.7%28.6%
50.00%106.452910,44128.6%100.0%
55.56%96.295114,28150.0%57.1%
88.89%97.280612,70675.0%100.0%
55.56%97.288211,46775.0%40.0%
55.56%95.672312,03950.0%60.0%
55.56%97.786112,78766.7%50.0%
75.00%87.487510,71080.0%66.7%
57.14%77.387510,78575.0%33.3%
42.86%75.873510,32566.7%25.0%
85.71%77.087111,26283.3%100.0%
71.43%76.173511,33280.0%50.0%
50.00%61.761410,6240.0%60.0%
83.33%67.91,14313,99850.0%100.0%
33.33%67.796512,2420.0%66.7%
33.33%66.686711,32825.0%50.0%
50.00%62.45439,94466.7%33.3%
83.33%67.183312,020100.0%80.0%
16.67%67.26078,27816.7%0.0%
60.00%56.01,16411,19766.7%50.0%
40.00%53.07276,78640.0%0.0%
20.00%57.793410,62525.0%0.0%
20.00%55.05978,21425.0%0.0%
40.00%53.45178,76125.0%100.0%
80.00%55.064712,91850.0%100.0%
40.00%56.783411,7270.0%66.7%
60.00%56.077611,837100.0%33.3%
40.00%56.374111,1560.0%50.0%
60.00%56.897912,10050.0%66.7%
80.00%56.51,08510,600100.0%66.7%

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Lissandra vs Karma - Frequently Asked Questions

How does Lissandra do against Karma in League of Legends?

Lissandra wins the Lissandra vs Karma matchup with a 80.0% win rate compared to Karma's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.7.

How does Lissandra do against Karma in the early game?

In the early game, Lissandra has the advantage against Karma with a 50.0% win rate versus 50.0%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Karma in the late game?

In the late game, Lissandra takes over the Lissandra vs Karma matchup with a 100.0% win rate compared to 0.0%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Karma matchup?

Lissandra wins the matchup against Karma with a 80.0% win rate in League of Legends patch 26.7. The 60.0 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Lissandra build against Karma?

The best Lissandra build against Karma includes Jak'Sho, The Protean, Zhonya's Hourglass, Malignance with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Karma?

The best Lissandra runes against Karma use the Resolve primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Karma matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Karma?

Yes, Lissandra has a favorable matchup against Karma with a 80.0% win rate. Lissandra strongly counters Karma in lane based on current patch 26.7 data.

How do I play Lissandra against Karma?

When playing Lissandra against Karma, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.