- Win Rate
- 0%
- Pick Rate
- 0%
- Ban Rate
- 0.6%
Karthus Mid Runes: Keystone & Shards
- Patch
- 26.20
- Matches
- 654,440
- Lane
- Mid
- Tier
- All Tiers
- Last Updated
- Oct 13, 2026 UTC
- Methodology
- Data Methodology
- Author
- Dakota Chinnick
Best Mid Karthus runes for LoL Patch 26.20 - Keystone from the Primary tree with Secondary secondary (0% WR, 0% pick rate). Karthus's optimal primary runes are {primaryRunes}. Secondary tree: {secondaryRunes}.
Primary Tree
Secondary Tree
Primary Tree
Secondary Tree
Every Karthus Mid Keystone and Secondary Tree (Patch 26.20)
109 gamesKarthus Mid runs Dark Harvest in 48% of games, with a 38.5% win rate. Precision is the usual secondary tree (54%). Standard stat shards: Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense).
Keystones
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Dark HarvestMost played | 47.7% | 38.5% | 52 |
 Deathfire Touch | 46.8% | 54.9% | 51 |
Secondary trees
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 PrecisionMost played | 54.1% | 44.1% | 59 |
 Sorcery | 38.5% | 45.2% | 42 |
Pick rate is the share of Karthus games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.
Karthus Minor Runes by Tree
Every minor rune Karthus players take, grouped by rune tree, with how often it is picked and how often it wins.
Sorcery
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Axiom ArcanistMost played | 82.6% | 52.2% | 90 |
 Gathering Storm | 55.0% | 51.7% | 60 |
Domination
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Cheap ShotMost played | 50.5% | 43.6% | 55 |
 Grisly Mementos | 44.0% | 35.4% | 48 |
 Ultimate Hunter | 42.2% | 43.5% | 46 |
Precision
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Presence of MindMost played | 45.9% | 48.0% | 50 |
Karthus Stat Shards
Which stat shards Karthus players choose in each of the three shard rows, and the win rate of each.
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Adaptive Force (offense)Most played | 97.2% | 47.2% | 106 |
| Adaptive Force (flex) | 93.6% | 45.1% | 102 |
 Health Scaling (defense) | 68.8% | 48.0% | 75 |
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Karthus Runes FAQ - Patch 26.20
What is the best keystone for Karthus Mid?
Dark Harvest: Karthus Mid takes it in 48% of ranked games and wins 38.5% of 52 games. Alternatives: Deathfire Touch (47%, 54.9%).
What stat shards should Karthus take?
Most Karthus players take Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.
What are the best Karthus runes in patch 26.20?
The best Karthus runes in patch 26.20 use the Primary tree with , and the Secondary tree with . This rune setup achieves a 0% win rate with a 0% pick rate.
What is the win rate for Karthus's best rune page?
Karthus's best rune page has a 0% win rate in patch 26.20, which is NaN% compared to Karthus's average win rate. This rune setup has a 0% pick rate among Karthus players.
What keystone should I use on Karthus?
your chosen keystone from the Primary tree is the best keystone rune for Karthus in patch 26.20. This keystone synergizes well with Karthus's kit and provides a 0% win rate.
What is Karthus's primary rune tree?
Karthus's primary rune tree is Primary. The optimal Primary runes for Karthus are , with your chosen keystone being the keystone of choice.
What is Karthus's secondary rune tree?
Karthus's best secondary rune tree is Secondary. The recommended Secondary runes are , which complement Karthus's Primary primary tree.
What are alternative rune setups for Karthus?
An alternative Karthus rune setup uses alternative keystone from the Primary tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Karthus's runes?
Karthus's top rune page has a 0% pick rate in patch 26.20. This indicates that 0% of Karthus players use the your chosen keystone setup with Primary and Secondary trees.