Lissandra - League of Legends Champion
Win Rate
50.2%
Pick Rate
1.2%

Lissandravs Mel

BMage
Patch26.4
Matches1,089,240
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 4, 2026
MethodologyData Methodology

Lissandra vs Mel is a decisive matchup in LoL patch 26.4. Lissandra wins with a 62.5% win rate (+25.0%) over Mel based on 41 games. Lissandra holds the advantage in both the early and late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Mel matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Mel - 62.5% win rateMel(62.5%)
Lissandra - 62.5% win rate in this matchup
Lissandra
62.5% WR
VS
Mel vs Lissandra matchup - 37.5% win rate
Mel
37.5% WR

Who Wins the Lissandra vs Mel Matchup?

Lissandra wins the Lissandra vs Mel matchup
Winner
Lissandra
Matches: 41
62.5%
Win Rate
37.5%
6.1
CS / min
7.0
773
DMG / min
1,023
11,624
Gold / game
13,163
158
Heal / min
74
449
DMG Mitigated / min
417
1.5
CC / min
1.2
70.6%
Early Game WR
29.4%
56.5%
Late Game WR
43.5%

Lissandra vs Mel Matchup Summary

The Lissandra vs Mel matchup is a decisive matchup in League of Legends ranked play. Based on 41 recent matches analyzed, Lissandra wins with a 62.5% win rate compared to Mel's 37.5%, giving Lissandra a 25.0 percentage point advantage. Lissandra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Mel players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Mel leads by 249 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Mel and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Mel away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Mel Laning Phase Breakdown

Mel wins the laning phase against Lissandra in League of Legends

Mel is favored during the laning phase against Lissandra, winning 3 out of 5 key stat categories. Mel holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.1Lissandra
7.0Mel
Mel significantly out-farms Lissandra by 0.9 CS per minute, accumulating an estimated 14 CS lead by mid game. This substantial farming gap gives Mel a major gold advantage and earlier item completions. Lissandra players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
773Lissandra
1,023Mel
Mel heavily out-damages Lissandra by 249 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Mel's sustained damage advantage take over.
Economy
11,624Lissandra
13,163Mel
Mel generates a commanding 1,539 more gold per game than Lissandra. This substantial economic advantage means Mel consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Lissandra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.5Lissandra
1.2Mel
Lissandra provides 0.3 seconds more crowd control per minute than Mel, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
608Lissandra
490Mel
Lissandra heals and mitigates 117 more damage per minute than Mel, providing moderate extra durability. This sustain edge allows Lissandra to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Mel.

Best Lissandra Build Against Mel

Crimson Lucidity is the optimal boots choice against Mel, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Mel are Luden's Echo, Shadowflame and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 60.0% win rate across 5 games — well above average and making it the top item path against Mel. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Mel matchup.

Early Game vs Late Game

Early Game
Lissandra
70.6%
+41.2% advantage
Lissandra early game win rateLissandra70.6%
Mel early game win rateMel29.4%
Late Game
Lissandra
56.5%
+13.0% advantage
Lissandra late game win rateLissandra56.5%
Mel late game win rateMel43.5%

Lissandra dominates the early game (first 15 minutes) with a commanding 70.6% win rate — a 41.2 percentage point lead over Mel. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lissandra is far superior in the late game (25+ minutes), boasting a 56.5% win rate — 13.0 points above Mel. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

Lissandra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Mel players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Lissandra Runes Against Mel

Sorcery rune tree - Lissandra primary runes vs MelSorcery
Arcane Comet - best Lissandra rune vs MelManaflow Band - best Lissandra rune vs MelTranscendence - best Lissandra rune vs MelScorch - best Lissandra rune vs Mel
Domination rune tree - Lissandra secondary runes vs MelDomination
Cheap Shot - best Lissandra rune vs MelUltimate Hunter - best Lissandra rune vs Mel
54.5% WR

Running Sorcery primary with Domination secondary allows Lissandra to press their advantage against Mel, amplifying the strengths that make this a favorable matchup.


Lissandra matchup data for League of Legends patch 26.4. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
55.98%2096.880911,76352.8%58.5%
55.97%1596.976911,56858.4%53.7%
49.00%1006.580311,85953.9%45.9%
48.39%946.882212,21051.2%46.0%
48.39%946.972011,47948.9%47.8%
45.74%946.879811,48653.2%38.3%
53.41%886.687511,82251.2%55.3%
55.70%796.675011,46151.4%59.1%
54.41%686.894611,94160.0%50.0%
41.27%636.968511,31242.4%40.0%
41.07%566.162910,34744.0%38.7%
48.00%516.679611,84644.0%52.0%
54.00%506.277011,93345.0%60.0%
46.94%496.376711,71652.6%43.3%
48.94%476.485811,29056.5%41.7%
60.00%456.775411,92857.1%61.3%
45.45%446.591812,40447.4%44.0%
53.66%426.670711,50452.6%54.5%
42.86%426.687312,16358.8%32.0%
62.50%416.177311,62470.6%56.5%
52.50%406.777210,82952.4%52.6%
51.28%396.987212,55163.2%40.0%
57.89%386.673510,88760.9%53.3%
48.57%366.770011,10344.4%52.9%
42.86%357.278511,92837.5%47.4%
66.67%336.679812,32658.3%71.4%
28.13%326.975910,82026.7%29.4%
64.52%316.769311,03860.0%68.8%
46.43%286.978010,70343.8%50.0%
42.86%285.280112,55736.4%47.1%
44.44%276.477411,45327.3%56.3%
44.00%256.270511,17153.9%33.3%
33.33%247.090412,24336.4%30.8%
56.52%236.781212,03445.5%66.7%
43.48%236.786713,30371.4%31.3%
47.62%226.577612,69050.0%46.7%
45.00%206.884811,33955.6%36.4%
42.11%195.875411,75366.7%30.8%
72.22%186.886312,48866.7%77.8%
47.06%187.090112,39060.0%41.7%
41.18%175.268011,24722.2%62.5%
70.59%175.883312,03683.3%63.6%
56.25%165.582811,22083.3%40.0%
50.00%167.47649,95162.5%37.5%
53.33%157.466410,56670.0%20.0%
45.45%111.95159,14833.3%50.0%
90.00%104.560210,870100.0%80.0%
30.00%101.952210,30433.3%28.6%
50.00%106.689710,50966.7%25.0%
50.00%107.876113,21133.3%75.0%
50.00%106.886610,98650.0%50.0%
50.00%104.05509,29166.7%25.0%
66.67%94.578211,55766.7%66.7%
66.67%93.981410,70175.0%60.0%
55.56%92.05308,78166.7%50.0%
22.22%96.873912,20633.3%16.7%
55.56%97.988112,08250.0%60.0%
44.44%97.58528,37457.1%0.0%
62.50%96.567310,30360.0%66.7%
12.50%86.264910,22825.0%0.0%
42.86%87.072111,1980.0%60.0%
62.50%87.074911,40875.0%50.0%
37.50%87.177210,74825.0%50.0%
28.57%77.61,10412,72750.0%0.0%
71.43%71.65829,690100.0%50.0%
42.86%75.785512,225100.0%33.3%
42.86%76.41,03315,01250.0%40.0%
28.57%77.564810,02740.0%0.0%
42.86%75.465312,28775.0%0.0%
57.14%72.85509,01433.3%75.0%
28.57%71.749710,6060.0%33.3%
42.86%71.956810,742100.0%20.0%
57.14%76.092414,1350.0%80.0%
42.86%71.96829,43133.3%50.0%
71.43%76.469011,06550.0%100.0%
57.14%76.889613,144100.0%50.0%
33.33%62.36078,40033.3%33.3%
50.00%66.583113,669100.0%40.0%
50.00%66.574010,74466.7%33.3%
33.33%61.64478,57050.0%0.0%
33.33%67.771111,40566.7%0.0%
16.67%65.756010,4190.0%25.0%
16.67%62.158610,8120.0%33.3%
25.00%51.963111,3670.0%25.0%
40.00%57.27389,34850.0%33.3%
0.00%56.597412,6900.0%0.0%
0.00%56.290811,5770.0%0.0%
40.00%55.25569,54566.7%0.0%
80.00%56.384010,265100.0%50.0%
40.00%55.969811,472100.0%0.0%
40.00%53.06539,19333.3%50.0%
60.00%51.637710,9390.0%60.0%
80.00%55.788511,943100.0%66.7%
100.00%56.785512,734100.0%100.0%
20.00%56.391413,6630.0%25.0%
80.00%56.699313,305100.0%66.7%
20.00%56.579612,1950.0%25.0%
60.00%58.01,0728,89450.0%100.0%
80.00%57.090014,195100.0%66.7%
60.00%56.765213,7960.0%75.0%
40.00%56.887212,56250.0%33.3%
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Lissandra vs Mel - Frequently Asked Questions

How does Lissandra do against Mel in League of Legends?

Lissandra wins the Lissandra vs Mel matchup with a 62.5% win rate compared to Mel's 37.5%, a 25.0 percentage point difference. This data is based on 41 recent ranked games in patch 26.4.

How does Lissandra do against Mel in the early game?

In the early game, Lissandra has the advantage against Mel with a 70.6% win rate versus 29.4%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Mel in the late game?

In the late game, Lissandra takes over the Lissandra vs Mel matchup with a 56.5% win rate compared to 43.5%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Mel matchup?

Lissandra wins the matchup against Mel with a 62.5% win rate in League of Legends patch 26.4. The 25.0 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 41 games analyzed.

What is the best Lissandra build against Mel?

The best Lissandra build against Mel includes Luden's Echo, Shadowflame, Malignance with Crimson Lucidity. This build achieves a 60.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Mel?

The best Lissandra runes against Mel use the Sorcery primary tree with Domination secondary. This rune setup achieves a 54.5% win rate in the Lissandra vs Mel matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Mel?

Yes, Lissandra has a favorable matchup against Mel with a 62.5% win rate. Lissandra strongly counters Mel in lane based on current patch 26.4 data.

How do I play Lissandra against Mel?

When playing Lissandra against Mel, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.