Lissandravs Seraphine
Lissandra vs Seraphine is a decisive matchup in LoL patch 26.14. Seraphine wins with a 53.9% win rate (+7.7%) over Lissandra based on 13 games. Seraphine wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Seraphine matchup.
Lissandra Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Lissandra vs Seraphine Matchup?
Lissandra vs Seraphine Matchup Summary
The Lissandra vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 13 recent matches analyzed, Seraphine wins with a 53.9% win rate compared to Lissandra's 46.1%, giving Seraphine a 7.7 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Lissandra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Lissandra reaches their power spikes, while Lissandra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in CS, where Lissandra leads by 0.8 CS/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Lissandra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Lissandra vs Seraphine Laning Phase Breakdown
Lissandra is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Lissandra Build Against Seraphine
Sorcerer's Shoes is the optimal boots choice against Seraphine, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Seraphine are Liandry's Torment, Redemption and Seraph's Embrace. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Seraphine matchup.
Early Game vs Late Game
Lissandra42.9%
Seraphine57.1%Lissandra50.0%Seraphine50.0%Seraphine dominates the early game (first 15 minutes) with a commanding 57.1% win rate — a 14.3 percentage point lead over Lissandra. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Late game (25+ minutes) is equally balanced, with Lissandra at 50.0% win rate — only 0.0 points ahead of Seraphine. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
The power dynamics shift as the game progresses — Seraphine has the edge early, but Lissandra gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Lissandra Runes Against Seraphine
Domination
Sorcery
The Domination and Sorcery rune setup gives Lissandra the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Lissandra matchup data for League of Legends patch 26.14. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 56.00% | 100 | 6.8 | 829 | 11,709 | 50.0% | 60.0% | |
| 54.88% | 82 | 6.5 | 902 | 11,766 | 63.3% | 50.0% | |
| 48.15% | 81 | 6.5 | 878 | 11,631 | 50.0% | 46.8% | |
| 55.07% | 69 | 6.7 | 801 | 12,597 | 53.6% | 56.1% | |
| 43.55% | 62 | 6.6 | 739 | 10,943 | 53.9% | 36.1% | |
| 56.45% | 62 | 6.7 | 808 | 10,829 | 51.9% | 60.0% | |
| 54.39% | 57 | 6.3 | 885 | 10,878 | 48.1% | 60.0% | |
| 49.12% | 57 | 6.7 | 902 | 11,348 | 41.7% | 54.5% | |
| 46.15% | 52 | 6.6 | 867 | 10,750 | 50.0% | 42.9% | |
| 42.00% | 50 | 6.8 | 833 | 11,887 | 52.4% | 34.5% | |
| 54.76% | 42 | 6.7 | 884 | 11,044 | 64.7% | 48.0% | |
| 51.28% | 39 | 5.5 | 708 | 11,601 | 25.0% | 63.0% | |
| 50.00% | 38 | 6.6 | 778 | 11,404 | 42.9% | 54.2% | |
| 44.44% | 36 | 6.6 | 710 | 11,331 | 30.8% | 52.2% | |
| 45.45% | 33 | 6.8 | 810 | 12,159 | 38.5% | 50.0% | |
| 33.33% | 27 | 6.0 | 723 | 11,765 | 40.0% | 31.8% | |
| 44.44% | 27 | 6.7 | 770 | 12,014 | 50.0% | 42.1% | |
| 62.96% | 27 | 6.3 | 837 | 10,834 | 75.0% | 53.3% | |
| 64.00% | 25 | 6.9 | 749 | 10,014 | 73.3% | 50.0% | |
| 47.83% | 23 | 6.4 | 920 | 11,174 | 44.4% | 50.0% | |
| 45.45% | 22 | 6.7 | 859 | 12,501 | 33.3% | 50.0% | |
| 50.00% | 22 | 6.2 | 793 | 12,368 | 50.0% | 50.0% | |
| 57.14% | 21 | 6.3 | 818 | 13,519 | 80.0% | 50.0% | |
| 61.90% | 21 | 6.8 | 902 | 11,203 | 80.0% | 45.5% | |
| 72.22% | 18 | 6.6 | 773 | 11,196 | 50.0% | 90.0% | |
| 50.00% | 18 | 6.6 | 973 | 13,124 | 50.0% | 50.0% | |
| 76.47% | 17 | 7.0 | 873 | 13,897 | 100.0% | 71.4% | |
| 41.18% | 17 | 6.5 | 893 | 12,802 | 60.0% | 33.3% | |
| 58.82% | 17 | 6.2 | 849 | 11,486 | 85.7% | 40.0% | |
| 41.18% | 17 | 6.1 | 753 | 10,545 | 40.0% | 41.7% | |
| 46.67% | 15 | 6.4 | 805 | 10,474 | 40.0% | 50.0% | |
| 46.67% | 15 | 7.0 | 785 | 12,212 | 66.7% | 41.7% | |
| 57.14% | 14 | 6.4 | 810 | 12,301 | 66.7% | 54.5% | |
| 42.86% | 14 | 6.9 | 793 | 11,287 | 42.9% | 42.9% | |
| 46.15% | 13 | 4.1 | 712 | 9,629 | 42.9% | 50.0% | |
| 61.54% | 13 | 6.9 | 918 | 13,162 | 100.0% | 50.0% | |
| 16.67% | 12 | 6.7 | 936 | 9,204 | 16.7% | 16.7% | |
| 63.64% | 11 | 7.0 | 956 | 13,587 | 100.0% | 50.0% | |
| 54.55% | 11 | 6.3 | 840 | 11,657 | 0.0% | 75.0% | |
| 27.27% | 11 | 6.8 | 917 | 13,304 | 33.3% | 25.0% | |
| 66.67% | 9 | 5.1 | 935 | 11,970 | 80.0% | 50.0% | |
| 44.44% | 9 | 6.8 | 802 | 12,256 | 100.0% | 28.6% | |
| 77.78% | 9 | 6.7 | 888 | 14,322 | 100.0% | 71.4% | |
| 33.33% | 9 | 6.4 | 746 | 8,585 | 40.0% | 25.0% | |
| 66.67% | 9 | 6.8 | 755 | 9,929 | 40.0% | 100.0% | |
| 55.56% | 9 | 7.3 | 843 | 11,385 | 66.7% | 50.0% | |
| 44.44% | 9 | 7.0 | 1,008 | 13,812 | 66.7% | 33.3% | |
| 87.50% | 8 | 6.7 | 1,218 | 11,330 | 100.0% | 66.7% | |
| 37.50% | 8 | 6.4 | 880 | 10,160 | 50.0% | 33.3% | |
| 42.86% | 7 | 4.6 | 731 | 11,076 | 25.0% | 66.7% | |
| 57.14% | 7 | 2.0 | 635 | 7,015 | 60.0% | 50.0% | |
| 33.33% | 6 | 5.3 | 827 | 10,999 | 50.0% | 25.0% | |
| 33.33% | 6 | 7.0 | 1,165 | 14,713 | 0.0% | 33.3% | |
| 50.00% | 6 | 5.8 | 850 | 12,748 | 100.0% | 25.0% | |
| 50.00% | 6 | 6.4 | 763 | 10,650 | 33.3% | 66.7% | |
| 66.67% | 6 | 2.8 | 607 | 9,991 | 100.0% | 50.0% | |
| 33.33% | 6 | 5.3 | 909 | 11,515 | 0.0% | 50.0% | |
| 20.00% | 5 | 1.8 | 418 | 7,057 | 0.0% | 100.0% | |
| 20.00% | 5 | 5.8 | 659 | 10,913 | 50.0% | 0.0% | |
| 80.00% | 5 | 6.7 | 920 | 12,965 | 100.0% | 66.7% | |
| 40.00% | 5 | 4.9 | 1,025 | 12,654 | 0.0% | 50.0% | |
| 40.00% | 5 | 3.1 | 638 | 12,160 | 100.0% | 25.0% | |
| 40.00% | 5 | 7.2 | 1,229 | 13,575 | 50.0% | 33.3% | |
| 40.00% | 5 | 5.8 | 723 | 14,862 | 0.0% | 40.0% | |
| 60.00% | 5 | 6.2 | 751 | 9,297 | 100.0% | 33.3% | |
| 100.00% | 5 | 7.2 | 1,070 | 11,231 | 100.0% | 100.0% | |
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Lissandra vs Seraphine - Frequently Asked Questions
How does Lissandra do against Seraphine in League of Legends?
Seraphine wins the Lissandra vs Seraphine matchup with a 53.9% win rate compared to Lissandra's 46.1%, a 7.7 percentage point difference. This data is based on 13 recent ranked games in patch 26.14.
How does Lissandra do against Seraphine in the early game?
In the early game, Seraphine has the advantage against Lissandra with a 57.1% win rate versus 42.9%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Lissandra do against Seraphine in the late game?
In the late game, Lissandra takes over the Lissandra vs Seraphine matchup with a 50.0% win rate compared to 50.0%. Lissandra scales better into team fights and objective contests after 25 minutes.
Who wins the Lissandra vs Seraphine matchup?
Seraphine wins the matchup against Lissandra with a 53.9% win rate in League of Legends patch 26.14. The 7.7 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 13 games analyzed.
What is the best Lissandra build against Seraphine?
The best Lissandra build against Seraphine includes Liandry's Torment, Redemption, Seraph's Embrace with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Lissandra runes against Seraphine?
The best Lissandra runes against Seraphine use the Domination primary tree with Sorcery secondary. This rune setup achieves a 25.0% win rate in the Lissandra vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.
Does Lissandra counter Seraphine?
No, Lissandra struggles against Seraphine with only a 46.1% win rate. Seraphine has the advantage in this matchup. Lissandra players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.
How do I play Lissandra against Seraphine?
When playing Lissandra against Seraphine, play cautiously and avoid Seraphine's power spikes. Focus on safe farming — you outscale Seraphine in the late game. Use the matchup-specific build and runes above to optimize your chances.