Seraphine - League of Legends Champion
Win Rate
50.9%
Pick Rate
4.9%

Seraphinevs Pantheon

ASupportMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Seraphine vs Pantheon is a decisive matchup in LoL patch 26.7. Seraphine wins with a 56.1% win rate (+12.1%) over Pantheon based on 66 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Pantheon matchup.

Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Pantheon - 56.1% win ratePantheon(56.1%)
Seraphine - 56.1% win rate in this matchup
Seraphine
56.1% WR
VS
Pantheon vs Seraphine matchup - 43.9% win rate
Pantheon
43.9% WR

Who Wins the Seraphine vs Pantheon Matchup?

Seraphine wins the Seraphine vs Pantheon matchup
Winner
Seraphine
Matches: 66
56.1%
Win Rate
43.9%
1.4
CS / min
1.5
462
DMG / min
671
10,057
Gold / game
11,038
314
Heal / min
153
340
DMG Mitigated / min
621
1.2
CC / min
0.8
56.0%
Early Game WR
44.0%
56.1%
Late Game WR
43.9%

Seraphine vs Pantheon Matchup Summary

The Seraphine vs Pantheon matchup is a decisive matchup in League of Legends ranked play. Based on 66 recent matches analyzed, Seraphine wins with a 56.1% win rate compared to Pantheon's 43.9%, giving Seraphine a 12.1 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Pantheon players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Seraphine leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine players can confidently pick into Pantheon and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Pantheon away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Pantheon Laning Phase Breakdown

Pantheon wins the laning phase against Seraphine in League of Legends

Pantheon is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Pantheon holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
1.4Seraphine
1.5Pantheon
Seraphine and Pantheon farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
462Seraphine
671Pantheon
Pantheon heavily out-damages Seraphine by 208 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Pantheon's sustained damage advantage take over.
Economy
10,057Seraphine
11,038Pantheon
Pantheon generates a commanding 980 more gold per game than Seraphine. This substantial economic advantage means Pantheon consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Seraphine
0.8Pantheon
Seraphine provides 0.4 seconds more crowd control per minute than Pantheon, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Seraphine coordinate with their jungler and control the pace of skirmishes.
Sustain
654Seraphine
774Pantheon
Pantheon heals and mitigates 120 more damage per minute than Seraphine, providing moderate extra durability. This sustain edge allows Pantheon to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Seraphine.

Best Seraphine Build Against Pantheon

Ionian Boots of Lucidity is the optimal boots choice against Pantheon, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Pantheon are Echoes of Helia, Moonstone Renewer and Diadem of Songs. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 60.0% win rate across 5 games — well above average and making it the top item path against Pantheon. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Pantheon matchup.

Early Game vs Late Game

Early Game
Seraphine
56.0%
+12.0% advantage
Seraphine early game win rateSeraphine56.0%
Pantheon early game win ratePantheon44.0%
Late Game
Seraphine
56.1%
+12.2% advantage
Seraphine late game win rateSeraphine56.1%
Pantheon late game win ratePantheon43.9%

Seraphine dominates the early game (first 15 minutes) with a commanding 56.0% win rate — a 12.0 percentage point lead over Pantheon. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 56.1% win rate — 12.2 points above Pantheon. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Pantheon players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Seraphine Runes Against Pantheon

Sorcery rune tree - Seraphine primary runes vs PantheonSorcery
Summon Aery - best Seraphine rune vs PantheonManaflow Band - best Seraphine rune vs PantheonTranscendence - best Seraphine rune vs PantheonGathering Storm - best Seraphine rune vs Pantheon
Resolve rune tree - Seraphine secondary runes vs PantheonResolve
Font of Life - best Seraphine rune vs PantheonRevitalize - best Seraphine rune vs Pantheon
62.5% WR

Running Sorcery primary with Resolve secondary allows Seraphine to press their advantage against Pantheon, amplifying the strengths that make this a favorable matchup.


Seraphine matchup data for League of Legends patch 26.7. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
54.18%2991.64439,72745.0%59.6%
44.49%2631.34388,73041.4%48.0%
53.94%2411.34619,24352.6%55.2%
53.01%1831.44589,30748.8%56.4%
53.59%1811.44469,09849.4%57.5%
53.66%1641.44779,15159.3%48.2%
51.57%1591.54879,18454.3%49.4%
56.96%1581.44609,12365.1%51.6%
51.45%1381.44108,92450.8%52.1%
57.58%1321.44559,01657.4%57.8%
44.44%1261.34078,50942.9%46.0%
48.72%1171.655210,13343.2%51.3%
55.17%1161.54939,75339.1%65.7%
48.28%1161.754110,06752.2%45.7%
54.29%1051.34268,52558.2%50.0%
47.57%1031.54449,60136.6%54.8%
53.92%1021.44648,93753.9%54.0%
50.50%1011.43578,58654.9%46.0%
65.31%982.04699,74265.0%65.5%
51.11%901.45449,00546.1%54.9%
60.67%891.45258,87651.2%69.6%
48.05%771.64329,06447.1%48.8%
48.48%661.64499,83052.0%46.3%
56.06%661.446210,05756.0%56.1%
59.09%661.34709,19553.3%63.9%
51.52%661.45339,38642.9%57.9%
50.00%561.34318,78350.0%50.0%
50.91%555.059410,15445.7%60.0%
61.11%541.45039,73561.1%61.1%
45.10%511.45549,19748.0%42.3%
56.00%501.64589,66571.4%44.8%
68.09%471.34338,79683.3%52.2%
41.30%461.44408,44340.7%42.1%
55.26%386.575312,73061.1%50.0%
41.67%361.55229,34566.7%23.8%
45.71%351.45389,51041.2%50.0%
51.43%356.577612,68062.5%42.1%
41.18%341.95239,70342.9%40.0%
62.50%324.466312,14861.5%63.2%
61.54%261.45069,89770.0%56.3%
57.69%265.866912,09666.7%50.0%
72.00%253.654911,21477.8%68.8%
47.83%231.34387,54662.5%14.3%
39.13%231.34279,80042.9%37.5%
45.45%225.768813,31257.1%40.0%
42.86%212.04569,77930.0%54.5%
60.00%206.873212,63062.5%58.3%
68.42%192.25288,37271.4%60.0%
52.63%194.566310,72362.5%45.5%
77.78%185.262111,90780.0%75.0%
50.00%182.23929,53214.3%72.7%
17.65%171.95419,5550.0%30.0%
68.75%166.175711,132100.0%44.4%
56.25%165.061711,17950.0%58.3%
37.50%161.44408,74328.6%44.4%
40.00%155.879112,89180.0%20.0%
53.33%152.65158,83558.3%33.3%
60.00%156.969012,35375.0%42.9%
57.14%141.65038,97662.5%50.0%
50.00%126.066912,17266.7%33.3%
58.33%121.95109,80057.1%60.0%
41.67%124.362911,9680.0%50.0%
50.00%125.572511,57837.5%75.0%
45.45%111.83348,40757.1%25.0%
45.45%111.448611,0260.0%50.0%
20.00%101.94449,6570.0%40.0%
30.00%106.083411,91850.0%16.7%
66.67%95.04869,88271.4%50.0%
66.67%96.791812,31350.0%100.0%
44.44%91.652310,69633.3%50.0%
66.67%95.06849,58460.0%75.0%
55.56%95.878611,74075.0%40.0%
62.50%86.375213,234100.0%50.0%
62.50%84.164710,851100.0%0.0%
62.50%86.072611,59850.0%75.0%
50.00%81.63948,88825.0%75.0%
50.00%82.659011,57450.0%50.0%
37.50%84.34689,60866.7%20.0%
50.00%86.075212,12750.0%50.0%
75.00%81.84619,71750.0%100.0%
50.00%84.75939,70720.0%100.0%
28.57%71.54699,3480.0%50.0%
57.14%72.24578,64566.7%50.0%
85.71%71.55068,91275.0%100.0%
42.86%71.44499,4630.0%60.0%
50.00%63.866510,38850.0%50.0%
50.00%61.253910,07150.0%50.0%
50.00%62.45769,27866.7%33.3%
50.00%65.060611,31766.7%33.3%
40.00%56.077711,01533.3%50.0%
20.00%55.151210,8920.0%25.0%
60.00%55.872310,033100.0%50.0%
20.00%51.43949,2580.0%33.3%
80.00%54.677910,15775.0%100.0%
40.00%52.76589,47233.3%50.0%

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Seraphine vs Pantheon - Frequently Asked Questions

How does Seraphine do against Pantheon in League of Legends?

Seraphine wins the Seraphine vs Pantheon matchup with a 56.1% win rate compared to Pantheon's 43.9%, a 12.1 percentage point difference. This data is based on 66 recent ranked games in patch 26.7.

How does Seraphine do against Pantheon in the early game?

In the early game, Seraphine has the advantage against Pantheon with a 56.0% win rate versus 44.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Pantheon in the late game?

In the late game, Seraphine takes over the Seraphine vs Pantheon matchup with a 56.1% win rate compared to 43.9%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Pantheon matchup?

Seraphine wins the matchup against Pantheon with a 56.1% win rate in League of Legends patch 26.7. The 12.1 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 66 games analyzed.

What is the best Seraphine build against Pantheon?

The best Seraphine build against Pantheon includes Echoes of Helia, Moonstone Renewer, Diadem of Songs with Ionian Boots of Lucidity. This build achieves a 60.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Pantheon?

The best Seraphine runes against Pantheon use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 62.5% win rate in the Seraphine vs Pantheon matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Pantheon?

Yes, Seraphine has a favorable matchup against Pantheon with a 56.1% win rate. Seraphine strongly counters Pantheon in lane based on current patch 26.7 data.

How do I play Seraphine against Pantheon?

When playing Seraphine against Pantheon, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.