Seraphine - League of Legends Champion
Win Rate
52.3%
Pick Rate
7.8%

Seraphinevs Pantheon

SSupportMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 5, 2026
MethodologyData Methodology

Seraphine vs Pantheon is a moderate matchup in LoL patch 26.11. Pantheon wins with a 51.6% win rate (+3.1%) over Seraphine based on 192 games. Seraphine wins the early laning phase while Pantheon scales better into the late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Pantheon matchup.

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Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 48.4% win rate in this matchup
Seraphine
48.4% WR
VS
Pantheon vs Seraphine matchup - 51.6% win rate
Pantheon
51.6% WR

Who Wins the Seraphine vs Pantheon Matchup?

Pantheon wins the Seraphine vs Pantheon matchup
Winner
Pantheon
Matches: 192
48.4%
Win Rate
51.6%
1.4
CS / min
1.6
497
DMG / min
710
9,418
Gold / game
10,530
285
Heal / min
147
360
DMG Mitigated / min
621
1.2
CC / min
0.8
51.2%
Early Game WR
48.8%
46.3%
Late Game WR
53.7%

Seraphine vs Pantheon Matchup Summary

The Seraphine vs Pantheon matchup is a moderate matchup in League of Legends ranked play. Based on 192 recent matches analyzed, Pantheon wins with a 51.6% win rate compared to Seraphine's 48.4%, giving Pantheon a 3.1 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Pantheon outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Pantheon reaches their power spikes, while Pantheon should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Seraphine leads by 0.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. While Pantheon is slightly favored, Seraphine can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Pantheon's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Pantheon Laning Phase Breakdown

Pantheon wins the laning phase against Seraphine in League of Legends

Pantheon is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Pantheon holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
1.4Seraphine
1.6Pantheon
Seraphine and Pantheon farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
497Seraphine
710Pantheon
Pantheon heavily out-damages Seraphine by 213 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Pantheon's sustained damage advantage take over.
Economy
9,418Seraphine
10,530Pantheon
Pantheon generates a commanding 1,112 more gold per game than Seraphine. This substantial economic advantage means Pantheon consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Seraphine
0.8Pantheon
Seraphine provides 0.4 seconds more crowd control per minute than Pantheon, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Seraphine coordinate with their jungler and control the pace of skirmishes.
Sustain
646Seraphine
768Pantheon
Pantheon heals and mitigates 122 more damage per minute than Seraphine, providing moderate extra durability. This sustain edge allows Pantheon to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Seraphine.

Best Seraphine Build Against Pantheon

Ionian Boots of Lucidity is the optimal boots choice against Pantheon, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Pantheon are Echoes of Helia, Moonstone Renewer and Diadem of Songs. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 9 games — well above average and making it the top item path against Pantheon. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Pantheon matchup.

Early Game vs Late Game

Early Game
Seraphine
51.2%
+2.4% advantage
Seraphine early game win rateSeraphine51.2%
Pantheon early game win ratePantheon48.8%
Late Game
Pantheon
53.7%
+7.4% advantage
Seraphine late game win rateSeraphine46.3%
Pantheon late game win ratePantheon53.7%

During the early laning phase (first 15 minutes), Seraphine has a meaningful 51.2% win rate, outperforming Pantheon by 2.4 percentage points. Seraphine players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

Pantheon is far superior in the late game (25+ minutes), boasting a 53.7% win rate — 7.4 points above Seraphine. Extended games heavily favor Pantheon, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Seraphine has the edge early, but Pantheon gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Seraphine Runes Against Pantheon

Sorcery rune tree - Seraphine primary runes vs PantheonSorcery
Arcane Comet - best Seraphine rune vs PantheonManaflow Band - best Seraphine rune vs PantheonTranscendence - best Seraphine rune vs PantheonScorch - best Seraphine rune vs Pantheon
Inspiration rune tree - Seraphine secondary runes vs PantheonInspiration
Biscuit Delivery - best Seraphine rune vs PantheonCosmic Insight - best Seraphine rune vs Pantheon
53.1% WR

The Sorcery and Inspiration rune setup gives Seraphine the best tools to compete against Pantheon in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Seraphine matchup data for League of Legends patch 26.11. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.75%7791.74669,35944.9%49.5%
50.91%5501.44939,17358.0%45.0%
49.45%5481.44879,00751.2%48.0%
50.83%5431.44879,19746.8%53.9%
52.69%5011.54979,35248.8%55.5%
50.21%4781.85269,25551.6%49.0%
48.69%4211.54709,01249.2%48.3%
50.00%3341.44539,01050.4%49.7%
50.91%3301.95249,71553.4%49.2%
51.72%3191.44699,56046.7%55.4%
52.44%3071.44938,93052.7%52.2%
53.17%2841.74839,53147.7%56.6%
52.84%2821.44878,90149.2%55.8%
50.78%2581.54449,24750.5%51.0%
47.97%2461.54669,32744.7%50.4%
54.85%2371.85849,76454.8%54.9%
54.85%2371.44528,96551.9%57.4%
53.07%2281.53918,66358.8%46.8%
54.63%2271.84989,66455.6%54.0%
43.13%2111.35028,90135.6%48.8%
52.22%2031.45229,03758.4%47.4%
43.22%1991.54988,96147.1%40.4%
48.44%1921.44979,41851.2%46.3%
53.45%1741.84629,23249.4%56.7%
49.70%1691.66149,70344.4%52.2%
52.26%1551.44799,11856.9%48.2%
57.53%1461.45699,69067.9%51.1%
54.48%1454.566211,52162.3%50.0%
52.52%1391.44899,05164.1%42.7%
61.29%1241.64819,07567.7%54.8%
50.00%1221.44628,51250.8%49.1%
50.00%1201.45089,23252.8%47.8%
51.30%1151.44638,90542.2%57.1%
59.13%1156.281412,23054.7%62.9%
53.49%861.54809,03567.5%41.3%
54.88%825.867711,89860.0%51.9%
61.25%804.878912,00275.9%52.9%
56.76%746.880712,47863.9%50.0%
53.42%732.05109,99152.0%54.2%
56.16%731.55149,44956.8%55.6%
46.88%641.54679,51052.0%43.6%
43.33%601.65579,12160.7%28.1%
48.33%602.14408,59548.3%48.4%
54.24%596.283112,84042.1%60.0%
54.24%593.359210,05860.9%50.0%
60.34%585.375111,90651.9%67.7%
63.16%572.056710,73279.0%55.3%
44.23%521.75759,42052.0%37.0%
51.06%472.04629,10847.6%53.9%
50.00%402.260810,02652.6%47.6%
56.76%376.389112,39562.5%52.4%
44.44%362.55159,08730.8%52.2%
60.61%334.259811,53455.6%62.5%
51.52%335.366611,60061.5%45.0%
42.42%336.281310,73542.1%42.9%
51.52%336.878711,42658.8%43.8%
65.63%321.64749,16373.3%58.8%
65.63%324.168110,15666.7%64.7%
58.06%311.64859,79966.7%52.6%
56.67%306.673310,93362.5%50.0%
41.38%291.45019,36630.8%50.0%
44.44%275.167710,72263.6%31.3%
62.96%271.649810,32862.5%63.2%
54.17%244.26249,65645.5%61.5%
50.00%222.45679,74940.0%58.3%
45.45%223.04909,41825.0%57.1%
63.64%222.250811,56760.0%64.7%
40.00%206.580113,55633.3%41.2%
55.00%206.779212,47966.7%45.5%
55.00%202.04629,45857.1%53.9%
45.00%205.871411,07240.0%50.0%
70.00%201.464510,69887.5%58.3%
63.16%191.443410,16060.0%64.3%
61.11%185.67038,05964.3%50.0%
58.82%176.286512,02650.0%63.6%
35.29%171.244610,23775.0%23.1%
75.00%166.791813,62771.4%77.8%
37.50%161.54798,92840.0%36.4%
60.00%156.776112,98866.7%55.6%
40.00%155.359710,54633.3%44.4%
60.00%151.646310,50775.0%54.5%
50.00%143.264710,32850.0%50.0%
50.00%142.65519,74250.0%50.0%
42.86%144.85849,77450.0%37.5%
53.85%136.392112,20066.7%42.9%
30.77%134.16039,87733.3%28.6%
61.54%133.15949,46842.9%83.3%
58.33%126.78259,19670.0%0.0%
50.00%124.36669,42433.3%66.7%
58.33%126.076411,19160.0%57.1%
72.73%116.175811,907100.0%66.7%
27.27%114.55499,3630.0%50.0%
54.55%116.266011,06050.0%60.0%
60.00%105.680311,24250.0%75.0%
80.00%101.44777,16187.5%50.0%
66.67%94.552110,244100.0%62.5%
44.44%91.84238,69366.7%33.3%
37.50%86.293011,95740.0%33.3%
62.50%81.66239,74233.3%80.0%
37.50%81.53958,01025.0%50.0%
37.50%81.34679,59625.0%50.0%
25.00%85.367010,06850.0%16.7%
25.00%83.45779,67325.0%25.0%
62.50%81.457011,7740.0%71.4%
75.00%85.470711,28850.0%83.3%
50.00%81.14638,69050.0%50.0%
50.00%86.298713,25366.7%40.0%
75.00%81.648710,73550.0%83.3%
85.71%71.45378,417100.0%0.0%
42.86%71.949210,03133.3%50.0%
71.43%73.163510,657100.0%60.0%
57.14%73.473912,184100.0%50.0%
100.00%73.15957,466100.0%100.0%
71.43%73.05208,01175.0%66.7%
33.33%67.382210,97625.0%50.0%
100.00%62.35489,903100.0%100.0%
83.33%62.247410,918100.0%80.0%
50.00%61.63829,86350.0%50.0%
100.00%55.957011,5490.0%100.0%
40.00%51.649610,44750.0%33.3%
60.00%51.256510,3000.0%75.0%
40.00%56.06469,77425.0%100.0%
40.00%53.864610,54966.7%0.0%
80.00%51.549910,15550.0%100.0%

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Seraphine vs Pantheon - Frequently Asked Questions

How does Seraphine do against Pantheon in League of Legends?

Pantheon wins the Seraphine vs Pantheon matchup with a 51.6% win rate compared to Seraphine's 48.4%, a 3.1 percentage point difference. This data is based on 192 recent ranked games in patch 26.11.

How does Seraphine do against Pantheon in the early game?

In the early game, Seraphine has the advantage against Pantheon with a 51.2% win rate versus 48.8%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Pantheon in the late game?

In the late game, Pantheon takes over the Seraphine vs Pantheon matchup with a 53.7% win rate compared to 46.3%. Pantheon scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Pantheon matchup?

Pantheon wins the matchup against Seraphine with a 51.6% win rate in League of Legends patch 26.11. The 3.1 percentage point advantage means Pantheon is moderately favored in this lane matchup based on 192 games analyzed.

What is the best Seraphine build against Pantheon?

The best Seraphine build against Pantheon includes Echoes of Helia, Moonstone Renewer, Diadem of Songs with Ionian Boots of Lucidity. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Pantheon?

The best Seraphine runes against Pantheon use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 53.1% win rate in the Seraphine vs Pantheon matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Pantheon?

No, Seraphine struggles against Pantheon with only a 48.4% win rate. Pantheon has the advantage in this matchup. Seraphine players should focus on safe farming and avoiding extended trades to minimize Pantheon's lead.

How do I play Seraphine against Pantheon?

When playing Seraphine against Pantheon, play cautiously and avoid Pantheon's power spikes. Look for jungle assistance and team-dependent plays since Pantheon has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.