Samira - League of Legends Champion
Win Rate
50.2%
Pick Rate
2.7%

Samiravs Karthus

BMarksmanAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Samira vs Karthus is a decisive matchup in LoL patch 26.7. Samira wins with a 75.0% win rate (+50.0%) over Karthus based on 12 games. Samira holds the advantage in both the early and late game. Below you'll find the best Samira build, runes, laning stats, and strategies for the Samira vs Karthus matchup.

Samira Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Samira performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 75.0% win rateKarthus(75.0%)
Samira - 75.0% win rate in this matchup
Samira
75.0% WR
VS
Karthus vs Samira matchup - 25.0% win rate
Karthus
25.0% WR

Who Wins the Samira vs Karthus Matchup?

Samira wins the Samira vs Karthus matchup
Winner
Samira
Matches: 12
75.0%
Win Rate
25.0%
6.5
CS / min
6.5
1,068
DMG / min
1,364
15,320
Gold / game
14,041
331
Heal / min
68
601
DMG Mitigated / min
401
0.1
CC / min
0.7
66.7%
Early Game WR
33.3%
83.3%
Late Game WR
16.7%

Samira vs Karthus Matchup Summary

The Samira vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 12 recent matches analyzed, Samira wins with a 75.0% win rate compared to Karthus's 25.0%, giving Samira a 50.0 percentage point advantage. Samira dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Karthus players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Karthus leads by 0.6s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Samira players can confidently pick into Karthus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Karthus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Samira vs Karthus Laning Phase Breakdown

Samira wins the laning phase against Karthus in League of Legends

Samira is favored during the laning phase against Karthus, winning 3 out of 5 key stat categories. Samira holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
6.5Samira
6.5Karthus
Samira and Karthus farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
1,068Samira
1,364Karthus
Karthus heavily out-damages Samira by 296 DMG/min, dominating both short trades and all-in fights. Samira should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
15,320Samira
14,041Karthus
Samira generates a commanding 1,278 more gold per game than Karthus. This substantial economic advantage means Samira consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karthus should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.1Samira
0.7Karthus
Karthus provides 0.6 seconds more crowd control per minute than Samira, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Karthus coordinate with their jungler and control the pace of skirmishes.
Sustain
932Samira
469Karthus
Samira vastly out-sustains Karthus, healing and mitigating 463 more damage per minute. This massive durability gap means Samira can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Samira
66.7%
+33.3% advantage
Samira early game win rateSamira66.7%
Karthus early game win rateKarthus33.3%
Late Game
Samira
83.3%
+66.7% advantage
Samira late game win rateSamira83.3%
Karthus late game win rateKarthus16.7%

Samira dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Karthus. This lopsided early game means Samira can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Samira is far superior in the late game (25+ minutes), boasting a 83.3% win rate — 66.7 points above Karthus. Extended games heavily favor Samira, whose kit and scaling make them a dominant force in team fights and objective control.

Samira holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Karthus players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Samira Runes Against Karthus

Precision rune tree - Samira primary runes vs KarthusPrecision
Conqueror - best Samira rune vs KarthusTriumph - best Samira rune vs KarthusLegend: Bloodline - best Samira rune vs KarthusLast Stand - best Samira rune vs Karthus
Inspiration rune tree - Samira secondary runes vs KarthusInspiration
Cash Back - best Samira rune vs KarthusBiscuit Delivery - best Samira rune vs Karthus
100.0% WR

Running Precision primary with Inspiration secondary allows Samira to press their advantage against Karthus, amplifying the strengths that make this a favorable matchup.


Samira matchup data for League of Legends patch 26.7. The table below shows Samira's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Samira build, runes, laning stats, and early vs late game analysis for that specific matchup.

Samira matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.80%2506.490614,78350.0%47.9%
47.85%2096.689514,51947.4%48.2%
51.20%2096.291414,69254.9%47.7%
47.29%2036.691414,23847.6%47.0%
41.48%1766.590814,43639.7%42.7%
50.90%1676.598714,86345.6%55.7%
54.30%1516.697515,18559.4%50.6%
51.05%1436.595014,37048.6%53.4%
52.29%1096.493214,22061.8%42.6%
48.60%1076.791213,41050.0%46.7%
53.95%766.292814,89060.6%48.8%
51.35%746.599614,13950.0%53.6%
52.11%716.593614,17758.5%43.3%
47.06%686.592213,35648.6%45.2%
50.00%686.51,00214,17644.1%55.9%
39.68%636.585114,52846.7%33.3%
57.89%576.795514,70461.5%54.8%
28.26%466.379911,46420.7%41.2%
41.86%436.287113,14330.8%58.8%
37.21%436.889313,07632.1%46.7%
45.95%376.31,09714,94644.4%47.4%
33.33%366.372112,47938.1%26.7%
60.00%306.778912,92650.0%71.4%
43.33%306.41,11316,25357.1%31.3%
53.33%306.195015,50341.7%61.1%
53.57%286.31,02214,25046.7%61.5%
46.15%266.61,02014,48350.0%41.7%
44.00%256.690012,73633.3%53.9%
36.36%226.197915,94330.0%41.7%
50.00%186.480112,39644.4%55.6%
42.86%146.779012,77542.9%42.9%
46.15%136.789414,31157.1%33.3%
75.00%126.51,06815,32066.7%83.3%
50.00%86.774513,13550.0%50.0%
28.57%76.593111,49820.0%50.0%
66.67%66.287413,9790.0%80.0%
16.67%66.298913,1600.0%33.3%
33.33%66.581713,03566.7%0.0%
0.00%65.956410,7450.0%0.0%
60.00%56.187611,48966.7%50.0%

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Samira vs Karthus - Frequently Asked Questions

How does Samira do against Karthus in League of Legends?

Samira wins the Samira vs Karthus matchup with a 75.0% win rate compared to Karthus's 25.0%, a 50.0 percentage point difference. This data is based on 12 recent ranked games in patch 26.7.

How does Samira do against Karthus in the early game?

In the early game, Samira has the advantage against Karthus with a 66.7% win rate versus 33.3%. Samira players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Samira do against Karthus in the late game?

In the late game, Samira takes over the Samira vs Karthus matchup with a 83.3% win rate compared to 16.7%. Samira scales better into team fights and objective contests after 25 minutes.

Who wins the Samira vs Karthus matchup?

Samira wins the matchup against Karthus with a 75.0% win rate in League of Legends patch 26.7. The 50.0 percentage point advantage means Samira is significantly favored in this lane matchup based on 12 games analyzed.

What is the best Samira build against Karthus?

The best Samira build against Karthus includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Samira runes against Karthus?

The best Samira runes against Karthus use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Samira vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Samira counter Karthus?

Yes, Samira has a favorable matchup against Karthus with a 75.0% win rate. Samira strongly counters Karthus in lane based on current patch 26.7 data.

How do I play Samira against Karthus?

When playing Samira against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.