Samira - League of Legends Champion
Win Rate
49.1%
Pick Rate
2.8%

Samiravs Karthus

DMarksmanAssassin
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Samira vs Karthus is a very close matchup in LoL patch 26.14. Samira wins with a 50.0% win rate (+0.0%) over Karthus based on 6 games. Karthus wins the early laning phase while Samira scales better into the late game. Below you'll find the best Samira build, runes, laning stats, and strategies for the Samira vs Karthus matchup.

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Samira Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Samira performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Samira - 50.0% win rate in this matchup
Samira
50.0% WR
VS
Karthus vs Samira matchup - 50.0% win rate
Karthus
50.0% WR

Who Wins the Samira vs Karthus Matchup?

Samira wins the Samira vs Karthus matchup
Winner
Samira
Matches: 6
50.0%
Win Rate
50.0%
6.3
CS / min
7.8
620
DMG / min
1,516
8,835
Gold / game
10,970
191
Heal / min
84
474
DMG Mitigated / min
327
0.0
CC / min
0.6
25.0%
Early Game WR
75.0%
100.0%
Late Game WR
0.0%

Samira vs Karthus Matchup Summary

The Samira vs Karthus matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Samira wins with a 50.0% win rate compared to Karthus's 50.0%, giving Samira a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Samira outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Samira reaches their power spikes, while Samira should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Karthus leads by 0.6s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Samira has a statistical edge, but the margin is close enough that respecting Karthus's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Samira vs Karthus Laning Phase Breakdown

Karthus wins the laning phase against Samira in League of Legends

Karthus is favored during the laning phase against Samira, winning 4 out of 5 key stat categories. Karthus holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.3Samira
7.8Karthus
Karthus significantly out-farms Samira by 1.5 CS per minute, accumulating an estimated 23 CS lead by mid game. This substantial farming gap gives Karthus a major gold advantage and earlier item completions. Samira players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
620Samira
1,516Karthus
Karthus heavily out-damages Samira by 897 DMG/min, dominating both short trades and all-in fights. Samira should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
8,835Samira
10,970Karthus
Karthus generates a commanding 2,136 more gold per game than Samira. This substantial economic advantage means Karthus consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Samira should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.0Samira
0.6Karthus
Karthus provides 0.6 seconds more crowd control per minute than Samira, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Karthus coordinate with their jungler and control the pace of skirmishes.
Sustain
664Samira
411Karthus
Samira vastly out-sustains Karthus, healing and mitigating 254 more damage per minute. This massive durability gap means Samira can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Karthus
75.0%
+50.0% advantage
Samira early game win rateSamira25.0%
Karthus early game win rateKarthus75.0%
Late Game
Samira
100.0%
+100.0% advantage
Samira late game win rateSamira100.0%
Karthus late game win rateKarthus0.0%

Karthus dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Samira. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Samira is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Karthus. Extended games heavily favor Samira, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Samira reaches their scaling breakpoints. If Samira survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Samira Runes Against Karthus

Precision rune tree - Samira primary runes vs KarthusPrecision
Conqueror - best Samira rune vs KarthusTriumph - best Samira rune vs KarthusLegend: Bloodline - best Samira rune vs KarthusLast Stand - best Samira rune vs Karthus
Domination rune tree - Samira secondary runes vs KarthusDomination
Taste of Blood - best Samira rune vs KarthusTreasure Hunter - best Samira rune vs Karthus
40.0% WR

The Precision primary with Domination secondary combination helps Samira maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Karthus.


Samira matchup data for League of Legends patch 26.14. The table below shows Samira's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Samira build, runes, laning stats, and early vs late game analysis for that specific matchup.

Samira matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.11%3186.285413,36452.7%44.9%
48.81%2526.385513,77248.0%49.4%
50.49%2046.390913,78948.2%52.1%
47.50%1606.285513,11054.7%41.2%
43.75%1446.289713,11146.3%41.6%
47.76%1346.690612,82442.9%52.1%
48.39%1246.293514,50445.5%50.7%
45.95%1116.484813,17644.2%47.5%
48.65%1116.394413,82030.4%61.5%
47.25%916.596013,32644.9%50.0%
45.88%856.392713,74646.5%45.2%
48.57%706.692413,57545.5%51.4%
54.29%706.696613,67251.4%57.1%
50.00%686.387112,87451.5%48.6%
47.69%656.389213,05643.5%50.0%
53.06%496.287713,16960.7%42.9%
59.09%446.289014,21858.8%59.3%
55.81%436.385913,48750.0%60.0%
52.63%386.487714,04362.5%45.5%
50.00%366.287712,88243.8%55.0%
70.00%306.41,01114,70864.7%76.9%
41.38%296.595814,05725.0%52.9%
51.72%296.185212,69442.9%60.0%
39.29%286.092012,71038.5%40.0%
51.85%277.592314,22253.9%50.0%
38.46%266.284512,17940.0%36.4%
50.00%206.593713,69342.9%53.9%
42.11%196.681112,83333.3%50.0%
73.68%196.51,06415,51275.0%72.7%
64.71%176.71,04514,97788.9%37.5%
43.75%166.777013,66322.2%71.4%
28.57%145.91,09313,6180.0%40.0%
46.15%135.41,06710,38457.1%33.3%
76.92%136.896114,150100.0%62.5%
91.67%127.21,21612,76083.3%100.0%
9.09%116.069111,49025.0%0.0%
27.27%116.386910,95814.3%50.0%
50.00%86.193713,493100.0%42.9%
0.00%86.685711,1570.0%0.0%
57.14%76.060510,66266.7%50.0%
28.57%76.676314,0780.0%40.0%
33.33%65.968411,47750.0%0.0%
66.67%67.094313,023100.0%50.0%
50.00%65.91,01113,9350.0%75.0%
66.67%67.385914,435100.0%33.3%
50.00%66.51,31815,39250.0%50.0%
50.00%66.36208,83525.0%100.0%

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Samira vs Karthus - Frequently Asked Questions

How does Samira do against Karthus in League of Legends?

Samira wins the Samira vs Karthus matchup with a 50.0% win rate compared to Karthus's 50.0%, a 0.0 percentage point difference. This data is based on 6 recent ranked games in patch 26.14.

How does Samira do against Karthus in the early game?

In the early game, Karthus has the advantage against Samira with a 75.0% win rate versus 25.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Samira do against Karthus in the late game?

In the late game, Samira takes over the Samira vs Karthus matchup with a 100.0% win rate compared to 0.0%. Samira scales better into team fights and objective contests after 25 minutes.

Who wins the Samira vs Karthus matchup?

Samira wins the matchup against Karthus with a 50.0% win rate in League of Legends patch 26.14. The 0.0 percentage point advantage means Samira is slightly favored in this lane matchup based on 6 games analyzed.

What is the best Samira build against Karthus?

The best Samira build against Karthus includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Samira runes against Karthus?

The best Samira runes against Karthus use the Precision primary tree with Domination secondary. This rune setup achieves a 40.0% win rate in the Samira vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Samira counter Karthus?

Yes, Samira has a favorable matchup against Karthus with a 50.0% win rate. Samira slightly edges out Karthus in lane based on current patch 26.14 data.

How do I play Samira against Karthus?

When playing Samira against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Karthus. Build the recommended items and runes for this specific matchup for the best results.