Karthus - League of Legends Champion
Win Rate
49.3%
Pick Rate
1.3%

Karthusvs Samira

DMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 18, 2026
MethodologyData Methodology

Karthus vs Samira is a decisive matchup in LoL patch 26.7. Samira wins with a 75.0% win rate (+50.0%) over Karthus based on 12 games. Samira holds the advantage in both the early and late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Samira matchup.

Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Samira - 25.0% win rateSamira(25.0%)
Karthus - 25.0% win rate in this matchup
Karthus
25.0% WR
VS
Samira vs Karthus matchup - 75.0% win rate
Samira
75.0% WR

Who Wins the Karthus vs Samira Matchup?

Samira wins the Karthus vs Samira matchup
Winner
Samira
Matches: 12
25.0%
Win Rate
75.0%
6.5
CS / min
6.5
1,364
DMG / min
1,068
14,041
Gold / game
15,320
68
Heal / min
331
401
DMG Mitigated / min
601
0.7
CC / min
0.1
33.3%
Early Game WR
66.7%
16.7%
Late Game WR
83.3%

Karthus vs Samira Matchup Summary

The Karthus vs Samira matchup is a decisive matchup in League of Legends ranked play. Based on 12 recent matches analyzed, Samira wins with a 75.0% win rate compared to Karthus's 25.0%, giving Samira a 50.0 percentage point advantage. Samira dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Karthus players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Karthus leads by 0.6s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Samira has a strong advantage in this matchup. Karthus players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Samira overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Samira Laning Phase Breakdown

Samira wins the laning phase against Karthus in League of Legends

Samira is favored during the laning phase against Karthus, winning 3 out of 5 key stat categories. Samira holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
6.5Karthus
6.5Samira
Karthus and Samira farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
1,364Karthus
1,068Samira
Karthus heavily out-damages Samira by 296 DMG/min, dominating both short trades and all-in fights. Samira should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
14,041Karthus
15,320Samira
Samira generates a commanding 1,278 more gold per game than Karthus. This substantial economic advantage means Samira consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karthus should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.7Karthus
0.1Samira
Karthus provides 0.6 seconds more crowd control per minute than Samira, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Karthus coordinate with their jungler and control the pace of skirmishes.
Sustain
469Karthus
932Samira
Samira vastly out-sustains Karthus, healing and mitigating 463 more damage per minute. This massive durability gap means Samira can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Samira
66.7%
+33.3% advantage
Karthus early game win rateKarthus33.3%
Samira early game win rateSamira66.7%
Late Game
Samira
83.3%
+66.7% advantage
Karthus late game win rateKarthus16.7%
Samira late game win rateSamira83.3%

Samira dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Karthus. This lopsided early game means Samira can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Samira is far superior in the late game (25+ minutes), boasting a 83.3% win rate — 66.7 points above Karthus. Extended games heavily favor Samira, whose kit and scaling make them a dominant force in team fights and objective control.

Samira holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Karthus players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Karthus Runes Against Samira

Domination rune tree - Karthus primary runes vs SamiraDomination
Dark Harvest - best Karthus rune vs SamiraCheap Shot - best Karthus rune vs SamiraGrisly Mementos - best Karthus rune vs SamiraTreasure Hunter - best Karthus rune vs Samira
Precision rune tree - Karthus secondary runes vs SamiraPrecision
Presence of Mind - best Karthus rune vs SamiraLast Stand - best Karthus rune vs Samira
100.0% WR

The Domination and Precision rune setup gives Karthus the best tools to compete against Samira in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Karthus matchup data for League of Legends patch 26.7. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.78%411.51,24613,63464.7%37.5%
45.00%401.71,19914,67650.0%41.7%
37.84%371.81,20313,45342.9%34.8%
59.46%376.81,20414,13361.1%57.9%
58.33%361.41,18514,86346.1%65.2%
42.86%351.61,14713,92340.0%45.0%
44.12%341.41,12214,48658.3%36.4%
65.63%326.31,26613,64771.4%61.1%
50.00%281.61,25415,99971.4%42.9%
44.44%276.11,21913,94641.7%46.7%
59.26%276.01,24814,69160.0%58.8%
60.00%251.51,20814,13545.5%71.4%
63.64%222.01,41215,52085.7%53.3%
63.64%226.01,33115,66162.5%64.3%
57.89%191.21,11113,72737.5%72.7%
36.84%196.51,28014,54516.7%46.1%
42.11%191.51,29515,86340.0%42.9%
57.89%191.41,15014,33071.4%50.0%
47.06%176.41,29415,52850.0%46.1%
76.47%171.21,06613,39466.7%87.5%
47.06%171.81,19814,51350.0%46.1%
75.00%161.41,29814,71466.7%80.0%
56.25%161.51,14013,02250.0%62.5%
26.67%151.31,03412,14627.3%25.0%
33.33%152.11,14213,21320.0%40.0%
35.71%141.11,12013,85225.0%50.0%
38.46%131.21,08313,38916.7%57.1%
38.46%131.41,18614,42740.0%37.5%
23.08%132.21,01010,85522.2%25.0%
46.15%136.01,24613,80450.0%44.4%
53.85%137.11,16413,19242.9%66.7%
50.00%123.71,31914,92180.0%28.6%
50.00%121.21,22814,55325.0%62.5%
25.00%126.51,36414,04133.3%16.7%
83.33%121.41,23815,11766.7%88.9%
25.00%121.61,12615,19325.0%25.0%
66.67%127.31,53918,810100.0%60.0%
25.00%121.21,07613,8870.0%60.0%
50.00%121.31,03811,95450.0%50.0%
63.64%116.81,40515,26060.0%66.7%
63.64%112.91,09213,99266.7%62.5%
27.27%111.31,12512,25020.0%33.3%
18.18%111.51,18312,73025.0%14.3%
45.45%116.71,23014,91440.0%50.0%
70.00%105.91,26912,68760.0%80.0%
60.00%107.01,16813,68960.0%60.0%
60.00%101.41,38813,38660.0%60.0%
70.00%107.11,33314,53075.0%66.7%
33.33%97.31,21213,57820.0%50.0%
44.44%93.899013,717100.0%28.6%
22.22%96.81,08812,89120.0%25.0%
66.67%91.61,56915,98675.0%60.0%
66.67%91.81,22714,33780.0%50.0%
33.33%94.81,07213,64425.0%40.0%
50.00%86.71,22114,59460.0%33.3%
37.50%81.81,33816,668100.0%28.6%
42.86%72.11,10612,56733.3%50.0%
42.86%72.21,17211,38060.0%0.0%
42.86%72.01,37413,47750.0%33.3%
42.86%77.21,12512,97033.3%50.0%
71.43%75.71,05413,5520.0%100.0%
71.43%71.21,49615,8850.0%83.3%
14.29%72.91,23213,7160.0%33.3%
57.14%72.01,19112,95466.7%50.0%
42.86%72.11,19315,03550.0%40.0%
85.71%71.61,34617,646100.0%80.0%
57.14%72.81,23515,411100.0%40.0%
50.00%66.91,27912,34425.0%100.0%
66.67%61.31,38414,20166.7%66.7%
66.67%61.396311,486100.0%50.0%
33.33%65.41,55214,5320.0%33.3%
33.33%62.481311,29650.0%0.0%
66.67%64.01,15114,6630.0%80.0%
16.67%61.41,19215,1100.0%20.0%
50.00%61.61,26817,2400.0%60.0%
60.00%55.91,19113,24966.7%50.0%
40.00%51.61,10312,8790.0%66.7%
40.00%56.81,00311,9160.0%50.0%
60.00%55.11,47719,353100.0%50.0%
20.00%52.81,10312,98150.0%0.0%
60.00%53.17289,38375.0%0.0%
60.00%57.11,03414,8450.0%75.0%
20.00%58.21,15513,53650.0%0.0%
60.00%52.382213,48466.7%50.0%

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Karthus vs Samira - Frequently Asked Questions

How does Karthus do against Samira in League of Legends?

Samira wins the Karthus vs Samira matchup with a 75.0% win rate compared to Karthus's 25.0%, a 50.0 percentage point difference. This data is based on 12 recent ranked games in patch 26.7.

How does Karthus do against Samira in the early game?

In the early game, Samira has the advantage against Karthus with a 66.7% win rate versus 33.3%. Samira players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Samira in the late game?

In the late game, Samira takes over the Karthus vs Samira matchup with a 83.3% win rate compared to 16.7%. Samira scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Samira matchup?

Samira wins the matchup against Karthus with a 75.0% win rate in League of Legends patch 26.7. The 50.0 percentage point advantage means Samira is significantly favored in this lane matchup based on 12 games analyzed.

What is the best Karthus build against Samira?

The best Karthus build against Samira includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Samira?

The best Karthus runes against Samira use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Karthus vs Samira matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Samira?

No, Karthus struggles against Samira with only a 25.0% win rate. Samira has the advantage in this matchup. Karthus players should focus on safe farming and avoiding extended trades to minimize Samira's lead.

How do I play Karthus against Samira?

When playing Karthus against Samira, play cautiously and avoid Samira's power spikes. Look for jungle assistance and team-dependent plays since Samira has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.