Karthus - League of Legends Champion
Win Rate
47.8%
Pick Rate
1.0%

Karthusvs Samira

FMage
Patch26.4
Matches1,089,240
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 1, 2026
MethodologyData Methodology

Karthus vs Samira is a very close matchup in LoL patch 26.4. Karthus wins with a 50.0% win rate (+0.0%) over Samira based on 14 games. Samira wins the early laning phase while Karthus scales better into the late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Samira matchup.

Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Samira - 50.0% win rateSamira(50.0%)
Karthus - 50.0% win rate in this matchup
Karthus
50.0% WR
VS
Samira vs Karthus matchup - 50.0% win rate
Samira
50.0% WR

Who Wins the Karthus vs Samira Matchup?

Karthus wins the Karthus vs Samira matchup
Winner
Karthus
Matches: 14
50.0%
Win Rate
50.0%
6.6
CS / min
6.9
1,299
DMG / min
886
14,190
Gold / game
14,883
83
Heal / min
323
362
DMG Mitigated / min
576
0.6
CC / min
0.1
33.3%
Early Game WR
66.7%
80.0%
Late Game WR
20.0%

Karthus vs Samira Matchup Summary

The Karthus vs Samira matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 14 recent matches analyzed, Karthus wins with a 50.0% win rate compared to Samira's 50.0%, giving Karthus a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Samira controls the early laning stage, but Karthus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Samira needs to press advantages before Karthus reaches their power spikes, while Karthus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Karthus leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus has a statistical edge, but the margin is close enough that respecting Samira's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Samira Laning Phase Breakdown

Samira wins the laning phase against Karthus in League of Legends

Samira is favored during the laning phase against Karthus, winning 3 out of 5 key stat categories. Samira holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
6.6Karthus
6.9Samira
Samira edges out Karthus by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Samira.
Damage
1,299Karthus
886Samira
Karthus heavily out-damages Samira by 413 DMG/min, dominating both short trades and all-in fights. Samira should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
14,190Karthus
14,883Samira
Samira earns 693 more gold per game than Karthus, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Samira slightly faster item completions.
Utility
0.6Karthus
0.1Samira
Karthus provides 0.5 seconds more crowd control per minute than Samira, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Karthus coordinate with their jungler and control the pace of skirmishes.
Sustain
446Karthus
898Samira
Samira vastly out-sustains Karthus, healing and mitigating 453 more damage per minute. This massive durability gap means Samira can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Samira
66.7%
+33.3% advantage
Karthus early game win rateKarthus33.3%
Samira early game win rateSamira66.7%
Late Game
Karthus
80.0%
+60.0% advantage
Karthus late game win rateKarthus80.0%
Samira late game win rateSamira20.0%

Samira dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Karthus. This lopsided early game means Samira can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karthus is far superior in the late game (25+ minutes), boasting a 80.0% win rate — 60.0 points above Samira. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Samira must aggressively press their early advantage and close out the game before Karthus reaches their scaling breakpoints. If Karthus survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Karthus Runes Against Samira

Domination rune tree - Karthus primary runes vs SamiraDomination
Dark Harvest - best Karthus rune vs SamiraCheap Shot - best Karthus rune vs SamiraDeep Ward - best Karthus rune vs SamiraUltimate Hunter - best Karthus rune vs Samira
Precision rune tree - Karthus secondary runes vs SamiraPrecision
Triumph - best Karthus rune vs SamiraLast Stand - best Karthus rune vs Samira
100.0% WR

The Domination primary with Precision secondary combination helps Karthus maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Samira.


Karthus matchup data for League of Legends patch 26.4. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.15%911.31,12014,20543.6%48.1%
53.75%801.41,17013,99651.4%55.8%
50.82%611.51,05713,98646.9%55.2%
29.63%541.41,01612,84637.0%22.2%
40.74%541.21,00013,57652.0%31.0%
52.83%531.31,10214,43138.9%60.0%
50.00%451.51,19013,93033.3%65.2%
40.91%451.81,24912,87530.4%52.4%
45.45%441.51,19115,81857.1%40.0%
52.50%401.41,23614,93635.3%65.2%
32.43%382.21,19113,00917.6%45.0%
34.21%381.71,17813,80943.8%27.3%
45.71%351.41,16415,70025.0%51.9%
42.86%352.31,16713,80647.4%37.5%
62.50%331.51,08914,67453.3%70.6%
48.48%331.41,17115,06972.7%36.4%
65.63%331.41,21614,02275.0%60.0%
62.50%326.51,18914,62655.6%71.4%
64.52%312.81,25315,72450.0%71.4%
48.39%312.11,17515,09744.4%50.0%
53.33%301.31,21014,87760.0%50.0%
46.67%301.41,19114,72825.0%61.1%
40.00%301.51,11813,17325.0%57.1%
44.83%291.81,24115,38344.4%45.0%
39.29%282.51,07512,06426.7%53.9%
35.71%287.11,29014,72144.4%31.6%
57.14%287.11,29715,28041.7%68.8%
51.85%271.41,22814,68446.7%58.3%
44.00%251.61,11913,32450.0%40.0%
72.00%256.31,27713,05966.7%80.0%
56.52%241.41,19115,35140.0%69.2%
52.17%242.61,12413,87854.5%50.0%
43.48%243.21,39917,31433.3%45.0%
63.64%231.61,13614,34070.0%58.3%
52.17%231.81,07112,13052.9%50.0%
50.00%222.71,11414,47033.3%61.5%
54.55%221.41,01012,48353.9%55.6%
63.16%216.71,13614,48055.6%70.0%
52.38%211.81,18014,64760.0%45.5%
31.58%191.51,14615,29033.3%30.8%
72.22%181.51,11315,76785.7%63.6%
38.89%186.61,52715,77250.0%30.0%
55.56%187.01,22214,45550.0%62.5%
55.56%186.41,39114,92450.0%58.3%
35.29%171.21,07613,70712.5%55.6%
64.71%171.31,09314,46150.0%72.7%
58.82%176.81,21213,67240.0%66.7%
25.00%166.11,41913,99733.3%14.3%
37.50%164.795710,61950.0%25.0%
50.00%152.61,40416,46460.0%44.4%
28.57%151.71,34113,51250.0%12.5%
26.67%153.01,16415,02350.0%18.2%
50.00%146.61,29914,19033.3%80.0%
50.00%146.91,25614,70960.0%44.4%
21.43%141.91,35614,81625.0%20.0%
42.86%140.994312,12740.0%50.0%
42.86%141.395413,81180.0%22.2%
64.29%141.21,15415,28666.7%62.5%
61.54%132.71,14112,85550.0%80.0%
53.85%136.41,42014,71957.1%50.0%
30.77%131.81,06312,25525.0%40.0%
30.77%136.01,07211,46337.5%20.0%
54.55%136.81,35716,646100.0%44.4%
61.54%132.41,13512,87742.9%83.3%
66.67%133.11,26416,01250.0%83.3%
66.67%125.81,29515,32833.3%77.8%
72.73%111.11,27216,663100.0%70.0%
45.45%117.01,24514,82250.0%42.9%
72.73%116.01,33313,29583.3%60.0%
54.55%112.21,17715,16533.3%62.5%
36.36%115.61,23516,02150.0%33.3%
40.00%106.01,13310,07637.5%50.0%
50.00%101.81,21715,398100.0%37.5%
40.00%104.51,10311,5370.0%80.0%
40.00%106.41,13011,07950.0%33.3%
22.22%91.51,22214,7250.0%28.6%
22.22%96.11,35912,4630.0%40.0%
44.44%90.91,26115,74633.3%50.0%
55.56%97.11,17415,10633.3%66.7%
62.50%87.31,18713,08480.0%33.3%
37.50%84.01,18314,7410.0%42.9%
25.00%81.91,16715,05133.3%20.0%
50.00%86.21,02912,25450.0%50.0%
57.14%77.81,10213,81460.0%50.0%
42.86%72.31,11414,1230.0%50.0%
28.57%70.71,44114,4700.0%28.6%
42.86%76.51,28816,0510.0%50.0%
42.86%77.01,11310,61742.9%0.0%
71.43%76.01,18712,40450.0%100.0%
66.67%61.11,09913,68366.7%66.7%
50.00%64.298014,2740.0%50.0%
83.33%62.61,11612,36066.7%100.0%
50.00%67.21,45614,141100.0%25.0%
83.33%66.797811,80075.0%100.0%
50.00%63.81,02213,025100.0%40.0%
33.33%61.71,24513,26050.0%25.0%
83.33%66.11,39813,26875.0%100.0%
66.67%67.41,17914,684100.0%50.0%
50.00%65.81,14812,20266.7%33.3%
50.00%66.31,10511,58650.0%50.0%
20.00%51.91,15715,63950.0%0.0%
40.00%51.31,18915,25350.0%33.3%
60.00%53.71,42612,66633.3%100.0%
50.00%56.11,47613,4680.0%66.7%
0.00%55.91,43715,4430.0%0.0%
60.00%53.21,30714,5490.0%100.0%
20.00%52.51,32215,7600.0%25.0%
40.00%53.51,36215,0670.0%50.0%
60.00%57.88979,91833.3%100.0%
0.00%57.285311,8850.0%0.0%
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Karthus vs Samira - Frequently Asked Questions

How does Karthus do against Samira in League of Legends?

Karthus wins the Karthus vs Samira matchup with a 50.0% win rate compared to Samira's 50.0%, a 0.0 percentage point difference. This data is based on 14 recent ranked games in patch 26.4.

How does Karthus do against Samira in the early game?

In the early game, Samira has the advantage against Karthus with a 66.7% win rate versus 33.3%. Samira players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Samira in the late game?

In the late game, Karthus takes over the Karthus vs Samira matchup with a 80.0% win rate compared to 20.0%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Samira matchup?

Karthus wins the matchup against Samira with a 50.0% win rate in League of Legends patch 26.4. The 0.0 percentage point advantage means Karthus is slightly favored in this lane matchup based on 14 games analyzed.

What is the best Karthus build against Samira?

The best Karthus build against Samira includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Samira?

The best Karthus runes against Samira use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Karthus vs Samira matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Samira?

Yes, Karthus has a favorable matchup against Samira with a 50.0% win rate. Karthus slightly edges out Samira in lane based on current patch 26.4 data.

How do I play Karthus against Samira?

When playing Karthus against Samira, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Samira. Build the recommended items and runes for this specific matchup for the best results.