Sejuani - League of Legends Champion
Win Rate
51.0%
Pick Rate
1.4%

Sejuanivs Seraphine

ATank
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 24, 2026
MethodologyData Methodology

Sejuani vs Seraphine is a decisive matchup in LoL patch 26.7. Seraphine wins with a 85.7% win rate (+71.4%) over Sejuani based on 7 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Sejuani build, runes, laning stats, and strategies for the Sejuani vs Seraphine matchup.

Sejuani Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Sejuani performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 14.3% win rateSeraphine(14.3%)
Sejuani - 14.3% win rate in this matchup
Sejuani
14.3% WR
VS
Seraphine vs Sejuani matchup - 85.7% win rate
Seraphine
85.7% WR

Who Wins the Sejuani vs Seraphine Matchup?

Seraphine wins the Sejuani vs Seraphine matchup
Winner
Seraphine
Matches: 7
14.3%
Win Rate
85.7%
1.2
CS / min
1.5
448
DMG / min
506
7,284
Gold / game
8,912
153
Heal / min
358
1,115
DMG Mitigated / min
296
1.0
CC / min
1.1
25.0%
Early Game WR
75.0%
0.0%
Late Game WR
100.0%

Sejuani vs Seraphine Matchup Summary

The Sejuani vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Seraphine wins with a 85.7% win rate compared to Sejuani's 14.3%, giving Seraphine a 71.4 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Sejuani players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Sejuani leads by 614 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Sejuani players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Sejuani vs Seraphine Laning Phase Breakdown

Seraphine wins the laning phase against Sejuani in League of Legends

Seraphine is favored during the laning phase against Sejuani, winning 4 out of 5 key stat categories. Seraphine holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
1.2Sejuani
1.5Seraphine
Seraphine edges out Sejuani by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Seraphine.
Damage
448Sejuani
506Seraphine
Seraphine deals 58 more champion damage per minute than Sejuani. While noticeable in extended trades, this gap can be offset by Sejuani choosing favorable fight windows, such as engaging when Seraphine's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
7,284Sejuani
8,912Seraphine
Seraphine generates a commanding 1,628 more gold per game than Sejuani. This substantial economic advantage means Seraphine consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Sejuani should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.0Sejuani
1.1Seraphine
Both Sejuani and Seraphine provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
1,268Sejuani
654Seraphine
Sejuani vastly out-sustains Seraphine, healing and mitigating 614 more damage per minute. This massive durability gap means Sejuani can absorb significant punishment and remain in lane while Seraphine is forced to recall. Building grievous wounds early is essential for Seraphine, and focusing on burst trade patterns rather than sustained fights is critical.

Best Sejuani Build Against Seraphine

Mercury's Treads is the optimal boots choice against Seraphine, providing the mobility and stats Sejuani needs most in this matchup. The top-performing core items for Sejuani against Seraphine are Locket of the Iron Solari, Thornmail and Bandlepipes. This combination gives Sejuani an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Sejuani vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
75.0%
+50.0% advantage
Sejuani early game win rateSejuani25.0%
Seraphine early game win rateSeraphine75.0%
Late Game
Seraphine
100.0%
+100.0% advantage
Sejuani late game win rateSejuani0.0%
Seraphine late game win rateSeraphine100.0%

Seraphine dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Sejuani. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Sejuani. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Sejuani players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Sejuani Runes Against Seraphine

Resolve rune tree - Sejuani primary runes vs SeraphineResolve
Aftershock - best Sejuani rune vs SeraphineFont of Life - best Sejuani rune vs SeraphineConditioning - best Sejuani rune vs SeraphineOvergrowth - best Sejuani rune vs Seraphine
Precision rune tree - Sejuani secondary runes vs SeraphinePrecision
Legend: Alacrity - best Sejuani rune vs SeraphineTriumph - best Sejuani rune vs Seraphine
50.0% WR

The Resolve and Precision rune setup gives Sejuani the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Sejuani matchup data for League of Legends patch 26.7. The table below shows Sejuani's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Sejuani build, runes, laning stats, and early vs late game analysis for that specific matchup.

Sejuani matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
50.00%660.955811,22240.7%56.4%
35.94%641.156310,83034.4%37.5%
51.67%601.066311,69050.0%52.9%
61.11%541.053311,82166.7%57.6%
44.68%471.258711,73222.7%64.0%
45.65%461.255711,66047.6%44.0%
39.02%411.058512,85046.1%35.7%
51.28%390.954311,00855.6%47.6%
63.89%361.361112,28858.3%66.7%
50.00%341.058312,21250.0%50.0%
61.29%311.672511,30250.0%70.6%
41.38%291.069812,37722.2%50.0%
39.29%281.556912,56544.4%36.8%
55.56%270.951413,08385.7%45.0%
56.00%251.062713,49650.0%57.9%
41.67%241.966911,94050.0%35.7%
40.91%221.056111,30855.6%30.8%
55.00%200.858311,51550.0%60.0%
45.00%201.066612,73137.5%50.0%
40.00%201.057911,86750.0%33.3%
55.00%201.166612,08550.0%56.3%
52.63%191.759610,84536.4%75.0%
73.68%191.866012,710100.0%54.5%
61.11%180.754111,18458.3%66.7%
50.00%182.968610,48833.3%66.7%
77.78%182.165112,14271.4%81.8%
47.06%172.466712,57450.0%45.5%
70.59%176.580611,52257.1%80.0%
70.59%171.369713,16671.4%70.0%
52.94%173.276011,09455.6%50.0%
56.25%161.070312,53666.7%50.0%
62.50%161.257511,14680.0%54.5%
68.75%160.948212,05071.4%66.7%
40.00%153.060212,23337.5%42.9%
57.14%141.455911,25071.4%42.9%
50.00%143.46109,37244.4%60.0%
46.15%130.956611,26357.1%33.3%
46.15%131.063312,83160.0%37.5%
25.00%123.172211,37140.0%14.3%
50.00%122.769012,74633.3%55.6%
63.64%111.073713,06975.0%57.1%
27.27%113.073110,06633.3%20.0%
36.36%111.371113,57350.0%28.6%
45.45%111.165714,72650.0%42.9%
50.00%105.575511,36533.3%75.0%
60.00%101.154710,52750.0%66.7%
70.00%101.55139,84962.5%100.0%
40.00%101.156712,46933.3%42.9%
55.56%94.976611,92325.0%80.0%
11.11%94.278111,88325.0%0.0%
77.78%93.075112,38950.0%85.7%
77.78%90.956812,318100.0%71.4%
77.78%90.937611,61575.0%80.0%
77.78%91.170413,219100.0%66.7%
37.50%85.468411,44675.0%0.0%
75.00%83.15889,72366.7%100.0%
14.29%71.24487,28425.0%0.0%
42.86%76.27279,54250.0%33.3%
28.57%71.659410,2930.0%40.0%
28.57%70.869113,472100.0%16.7%
57.14%71.661513,0250.0%57.1%
28.57%71.154410,29433.3%0.0%
42.86%73.054610,31550.0%33.3%
66.67%62.871512,18866.7%66.7%
66.67%63.846410,551100.0%0.0%
50.00%62.073111,6910.0%100.0%
33.33%64.269910,7560.0%50.0%
50.00%61.663813,7210.0%75.0%
66.67%62.867912,21150.0%75.0%
33.33%63.271811,1080.0%66.7%
50.00%66.91,00711,32166.7%33.3%
66.67%65.47799,57633.3%100.0%
66.67%66.699811,402100.0%33.3%
50.00%66.56327,73260.0%0.0%
20.00%56.77327,9020.0%33.3%
60.00%51.069713,7970.0%75.0%
20.00%52.444210,08420.0%0.0%
40.00%54.566312,4400.0%50.0%
20.00%54.774912,1250.0%33.3%

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Sejuani vs Seraphine - Frequently Asked Questions

How does Sejuani do against Seraphine in League of Legends?

Seraphine wins the Sejuani vs Seraphine matchup with a 85.7% win rate compared to Sejuani's 14.3%, a 71.4 percentage point difference. This data is based on 7 recent ranked games in patch 26.7.

How does Sejuani do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Sejuani with a 75.0% win rate versus 25.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Sejuani do against Seraphine in the late game?

In the late game, Seraphine takes over the Sejuani vs Seraphine matchup with a 100.0% win rate compared to 0.0%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Sejuani vs Seraphine matchup?

Seraphine wins the matchup against Sejuani with a 85.7% win rate in League of Legends patch 26.7. The 71.4 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Sejuani build against Seraphine?

The best Sejuani build against Seraphine includes Locket of the Iron Solari, Thornmail, Bandlepipes with Mercury's Treads. Check the matchup breakdown above for the full item path and build order.

What are the best Sejuani runes against Seraphine?

The best Sejuani runes against Seraphine use the Resolve primary tree with Precision secondary. This rune setup achieves a 50.0% win rate in the Sejuani vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Sejuani counter Seraphine?

No, Sejuani struggles against Seraphine with only a 14.3% win rate. Seraphine has the advantage in this matchup. Sejuani players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Sejuani against Seraphine?

When playing Sejuani against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.