Senna - League of Legends Champion
Win Rate
52.3%
Pick Rate
7.9%

Sennavs Lissandra

SSupportMarksman
Patch26.13
Matches265,623
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 8, 2026
MethodologyData Methodology

Senna vs Lissandra is a decisive matchup in LoL patch 26.13. Senna wins with a 80.0% win rate (+60.0%) over Lissandra based on 5 games. Senna holds the advantage in both the early and late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Lissandra matchup.

Metabot Logo
MetaBot Desktop
Live In-Game Overlays
Join Our Discord
Bug reports, feature requests & developer chat
Join Discord

Senna Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Senna - 80.0% win rate in this matchup
Senna
80.0% WR
VS
Lissandra vs Senna matchup - 20.0% win rate
Lissandra
20.0% WR

Who Wins the Senna vs Lissandra Matchup?

Senna wins the Senna vs Lissandra matchup
Winner
Senna
Matches: 5
80.0%
Win Rate
20.0%
3.7
CS / min
4.8
1,003
DMG / min
933
12,038
Gold / game
11,855
472
Heal / min
195
369
DMG Mitigated / min
399
1.4
CC / min
1.9
100.0%
Early Game WR
0.0%
66.7%
Late Game WR
33.3%

Senna vs Lissandra Matchup Summary

The Senna vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Senna wins with a 80.0% win rate compared to Lissandra's 20.0%, giving Senna a 60.0 percentage point advantage. Senna dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Lissandra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Senna leads by 248 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Senna players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Senna vs Lissandra Laning Phase Breakdown

Senna wins the laning phase against Lissandra in League of Legends

Senna is favored during the laning phase against Lissandra, winning 3 out of 5 key stat categories. Senna holds advantages in damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
3.7Senna
4.8Lissandra
Lissandra significantly out-farms Senna by 1.1 CS per minute, accumulating an estimated 16 CS lead by mid game. This substantial farming gap gives Lissandra a major gold advantage and earlier item completions. Senna players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
1,003Senna
933Lissandra
Senna deals 70 more champion damage per minute than Lissandra. While noticeable in extended trades, this gap can be offset by Lissandra choosing favorable fight windows, such as engaging when Senna's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
12,038Senna
11,855Lissandra
Senna and Lissandra generate nearly equal gold per game, with just a 184 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.4Senna
1.9Lissandra
Lissandra provides 0.5 seconds more crowd control per minute than Senna, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
842Senna
594Lissandra
Senna vastly out-sustains Lissandra, healing and mitigating 248 more damage per minute. This massive durability gap means Senna can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Senna
100.0%
+100.0% advantage
Senna early game win rateSenna100.0%
Lissandra early game win rateLissandra0.0%
Late Game
Senna
66.7%
+33.3% advantage
Senna late game win rateSenna66.7%
Lissandra late game win rateLissandra33.3%

Senna dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Lissandra. This lopsided early game means Senna can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Senna is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Lissandra. Extended games heavily favor Senna, whose kit and scaling make them a dominant force in team fights and objective control.

Senna holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Lissandra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Senna Runes Against Lissandra

Sorcery rune tree - Senna primary runes vs LissandraSorcery
Deathfire Touch - best Senna rune vs LissandraManaflow Band - best Senna rune vs LissandraCelerity - best Senna rune vs LissandraGathering Storm - best Senna rune vs Lissandra
Inspiration rune tree - Senna secondary runes vs LissandraInspiration
Magical Footwear - best Senna rune vs LissandraJack Of All Trades - best Senna rune vs Lissandra
100.0% WR

Running Sorcery primary with Inspiration secondary allows Senna to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.


Senna matchup data for League of Legends patch 26.13. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.

Senna matchup win rates and stats in League of Legends patch 26.13
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.05%2312.256410,24644.2%51.2%
57.94%2145.880413,13757.1%58.5%
51.38%1815.676412,41257.6%45.8%
48.02%1775.876712,97749.2%47.3%
46.54%1596.078312,66242.3%50.0%
49.04%1575.776812,61847.8%50.0%
42.96%1422.257310,46732.8%50.6%
45.13%1131.664110,44045.5%44.9%
55.36%1125.785512,90455.3%55.4%
54.37%1031.660110,26453.3%55.2%
59.14%936.080313,11050.0%64.4%
42.70%896.086913,20635.5%46.5%
52.81%891.767410,99152.5%53.1%
51.76%851.765810,21662.2%43.8%
44.05%843.270412,02941.2%46.0%
54.88%821.660110,27954.2%55.9%
50.72%695.669412,21755.2%47.5%
49.25%675.781712,96140.7%55.0%
49.23%651.76139,99847.1%51.6%
54.69%642.775711,04661.5%50.0%
45.31%645.981612,89350.0%42.1%
50.00%621.953710,46754.5%47.5%
55.00%605.577511,72758.1%51.7%
50.85%591.858610,72957.1%47.4%
55.17%581.66009,98152.2%57.1%
54.55%551.853111,03245.0%60.0%
56.60%536.286814,54847.6%62.5%
47.06%511.657910,45352.0%42.3%
51.02%491.76029,32044.0%58.3%
34.69%492.05829,98033.3%35.7%
51.02%496.280413,21356.0%45.8%
52.08%481.855710,09455.6%50.0%
65.22%465.980411,96655.6%79.0%
57.78%451.85729,51271.4%45.8%
52.27%446.376512,19256.5%47.6%
48.84%436.073512,37842.9%54.5%
52.38%421.87549,79945.0%59.1%
50.00%402.960111,31860.0%44.0%
42.50%401.765610,02938.9%45.5%
60.53%381.67409,59659.1%62.5%
69.44%361.564510,50676.9%65.2%
44.12%346.473811,81438.1%53.9%
47.06%341.772210,97758.8%35.3%
63.64%331.567611,03076.5%50.0%
56.25%321.572810,67745.5%61.9%
60.00%305.772012,42078.6%43.8%
43.33%301.55959,54943.8%42.9%
58.62%296.181912,77054.5%61.1%
60.71%281.961811,85850.0%66.7%
60.71%281.670610,86146.1%73.3%
61.54%265.983312,40666.7%54.5%
42.31%264.968813,23620.0%47.6%
68.00%254.272312,03380.0%60.0%
40.91%221.867411,38633.3%42.1%
40.00%201.669510,35550.0%33.3%
45.00%205.785913,77885.7%23.1%
50.00%203.775512,28650.0%50.0%
61.11%181.869311,94550.0%66.7%
76.47%172.674211,18780.0%75.0%
64.71%172.163611,75480.0%58.3%
56.25%161.770210,55566.7%42.9%
46.67%151.76658,82240.0%60.0%
42.86%142.052910,565100.0%27.3%
35.71%145.383714,5500.0%50.0%
38.46%131.657810,94450.0%33.3%
76.92%135.91,00213,71662.5%100.0%
66.67%122.580310,80375.0%62.5%
58.33%125.081114,20420.0%85.7%
50.00%125.477212,26640.0%57.1%
50.00%121.860710,24350.0%50.0%
50.00%125.790114,95640.0%57.1%
66.67%122.168011,63650.0%75.0%
54.55%111.477912,10166.7%50.0%
50.00%101.66549,34850.0%50.0%
55.56%91.661010,29050.0%60.0%
66.67%96.577013,97850.0%80.0%
77.78%91.981711,28366.7%83.3%
62.50%86.31,10712,29166.7%60.0%
87.50%81.982511,828100.0%83.3%
71.43%72.85719,81733.3%100.0%
14.29%72.451410,64633.3%0.0%
33.33%64.26419,9550.0%50.0%
83.33%62.468312,6240.0%83.3%
66.67%65.772615,72650.0%75.0%
40.00%56.381313,4400.0%50.0%
60.00%51.24266,44760.0%0.0%
20.00%51.865611,8750.0%25.0%
20.00%51.45457,7010.0%50.0%
80.00%51.56989,73950.0%100.0%
20.00%52.481111,6160.0%25.0%
40.00%56.085412,0420.0%66.7%
60.00%54.774613,136100.0%50.0%
60.00%54.882612,214100.0%50.0%
80.00%53.71,00312,038100.0%66.7%
40.00%52.17829,39933.3%50.0%

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Senna vs Lissandra - Frequently Asked Questions

How does Senna do against Lissandra in League of Legends?

Senna wins the Senna vs Lissandra matchup with a 80.0% win rate compared to Lissandra's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.13.

How does Senna do against Lissandra in the early game?

In the early game, Senna has the advantage against Lissandra with a 100.0% win rate versus 0.0%. Senna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Senna do against Lissandra in the late game?

In the late game, Senna takes over the Senna vs Lissandra matchup with a 66.7% win rate compared to 33.3%. Senna scales better into team fights and objective contests after 25 minutes.

Who wins the Senna vs Lissandra matchup?

Senna wins the matchup against Lissandra with a 80.0% win rate in League of Legends patch 26.13. The 60.0 percentage point advantage means Senna is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Senna build against Lissandra?

The best Senna build against Lissandra includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Senna runes against Lissandra?

The best Senna runes against Lissandra use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Senna vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Senna counter Lissandra?

Yes, Senna has a favorable matchup against Lissandra with a 80.0% win rate. Senna strongly counters Lissandra in lane based on current patch 26.13 data.

How do I play Senna against Lissandra?

When playing Senna against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.