Senna - League of Legends Champion
Win Rate
50.3%
Pick Rate
4.5%

Sennavs Miss Fortune

BSupportMarksman
Patch26.4
Matches1,089,240
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 5, 2026
MethodologyData Methodology

Senna vs Miss Fortune is a decisive matchup in LoL patch 26.4. Senna wins with a 54.4% win rate (+8.9%) over Miss Fortune based on 170 games. Senna holds the advantage in both the early and late game. Below you'll find the best Senna build, runes, laning stats, and strategies for the Senna vs Miss Fortune matchup.

Senna Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Senna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Miss Fortune - 54.4% win rateMiss Fortune(54.4%)
Senna - 54.4% win rate in this matchup
Senna
54.4% WR
VS
Miss Fortune vs Senna matchup - 45.6% win rate
Miss Fortune
45.6% WR

Who Wins the Senna vs Miss Fortune Matchup?

Senna wins the Senna vs Miss Fortune matchup
Winner
Senna
Matches: 170
54.4%
Win Rate
45.6%
6.0
CS / min
6.6
798
DMG / min
956
13,330
Gold / game
14,486
417
Heal / min
187
368
DMG Mitigated / min
482
1.2
CC / min
0.3
54.5%
Early Game WR
45.5%
54.4%
Late Game WR
45.6%

Senna vs Miss Fortune Matchup Summary

The Senna vs Miss Fortune matchup is a decisive matchup in League of Legends ranked play. Based on 170 recent matches analyzed, Senna wins with a 54.4% win rate compared to Miss Fortune's 45.6%, giving Senna a 8.9 percentage point advantage. Senna dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Miss Fortune players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Senna leads by 0.9s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Senna players can confidently pick into Miss Fortune and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Miss Fortune away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Senna vs Miss Fortune Laning Phase Breakdown

Miss Fortune wins the laning phase against Senna in League of Legends

Miss Fortune is favored during the laning phase against Senna, winning 3 out of 5 key stat categories. Miss Fortune holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.0Senna
6.6Miss Fortune
Miss Fortune edges out Senna by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 9 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Miss Fortune.
Damage
798Senna
956Miss Fortune
Miss Fortune heavily out-damages Senna by 159 DMG/min, dominating both short trades and all-in fights. Senna should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Miss Fortune's sustained damage advantage take over.
Economy
13,330Senna
14,486Miss Fortune
Miss Fortune generates a commanding 1,157 more gold per game than Senna. This substantial economic advantage means Miss Fortune consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Senna should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Senna
0.3Miss Fortune
Senna brings significantly more crowd control than Miss Fortune, with 0.9 more seconds of CC per minute. This large utility gap makes Senna far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Miss Fortune should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
785Senna
669Miss Fortune
Senna heals and mitigates 116 more damage per minute than Miss Fortune, providing moderate extra durability. This sustain edge allows Senna to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Miss Fortune.

Best Senna Build Against Miss Fortune

Boots of Swiftness is the optimal boots choice against Miss Fortune, providing the mobility and stats Senna needs most in this matchup. The top-performing core items for Senna against Miss Fortune are Dawncore, Moonstone Renewer and Black Cleaver. This combination gives Senna an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Senna vs Miss Fortune matchup.

Early Game vs Late Game

Early Game
Senna
54.5%
+9.1% advantage
Senna early game win rateSenna54.5%
Miss Fortune early game win rateMiss Fortune45.5%
Late Game
Senna
54.4%
+8.7% advantage
Senna late game win rateSenna54.4%
Miss Fortune late game win rateMiss Fortune45.6%

Senna dominates the early game (first 15 minutes) with a commanding 54.5% win rate — a 9.1 percentage point lead over Miss Fortune. This lopsided early game means Senna can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Senna is far superior in the late game (25+ minutes), boasting a 54.4% win rate — 8.7 points above Miss Fortune. Extended games heavily favor Senna, whose kit and scaling make them a dominant force in team fights and objective control.

Senna holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Miss Fortune players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Senna Runes Against Miss Fortune

Precision rune tree - Senna primary runes vs Miss FortunePrecision
Press the Attack - best Senna rune vs Miss FortunePresence of Mind - best Senna rune vs Miss FortuneLegend: Alacrity - best Senna rune vs Miss FortuneCut Down - best Senna rune vs Miss Fortune
Sorcery rune tree - Senna secondary runes vs Miss FortuneSorcery
Manaflow Band - best Senna rune vs Miss FortuneCelerity - best Senna rune vs Miss Fortune
63.6% WR

Running Precision primary with Sorcery secondary allows Senna to press their advantage against Miss Fortune, amplifying the strengths that make this a favorable matchup.


Senna matchup data for League of Legends patch 26.4. The table below shows Senna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Senna build, runes, laning stats, and early vs late game analysis for that specific matchup.

Senna matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.39%4911.45579,95251.1%47.9%
45.45%3871.749510,59340.5%48.9%
52.53%3581.35209,99246.3%57.8%
43.94%3311.45429,97345.1%42.9%
50.96%3151.358510,14052.7%49.4%
45.25%3056.379913,10739.7%51.0%
51.92%2881.753210,62040.4%59.0%
49.22%2561.455010,49449.0%49.4%
45.73%2361.455410,08543.3%48.3%
53.28%2301.360410,38164.8%45.6%
50.00%2221.45069,72255.0%45.0%
55.50%2096.283613,43250.5%59.6%
52.68%2052.160710,88052.4%52.9%
50.99%2021.35259,50254.5%46.7%
48.48%2011.35799,87444.6%51.9%
50.00%1966.681413,32448.4%51.5%
53.72%1891.359910,19950.0%56.9%
52.15%1871.452010,21350.0%54.0%
48.62%1811.452410,15346.0%51.1%
54.44%1706.079813,33054.5%54.4%
57.23%1686.284512,99056.8%57.6%
46.34%1662.470111,09640.8%51.1%
51.88%1611.44449,73258.2%45.7%
51.27%1611.650510,16748.0%54.3%
46.75%1555.074912,55147.3%46.3%
51.30%1546.585413,26052.0%50.6%
53.29%1541.457010,51453.1%53.4%
47.62%1486.591413,77642.2%51.8%
46.62%1331.849410,45437.3%54.0%
47.66%1291.467710,21647.5%47.8%
47.79%1141.468110,14049.2%46.1%
50.00%1121.35339,32952.5%46.9%
50.49%1055.772212,61657.1%44.4%
47.57%1051.358110,33451.2%45.0%
47.62%1051.35719,91933.3%58.3%
59.80%1022.861212,07755.3%62.5%
50.51%1001.557010,44946.5%53.6%
55.32%956.384313,97560.5%51.0%
48.91%926.292914,03443.9%52.9%
41.30%921.54759,23547.1%34.1%
54.88%841.753710,28047.2%60.9%
53.57%846.383313,72947.4%58.7%
50.00%836.285213,04447.6%52.5%
60.98%821.459910,42470.0%52.4%
49.38%816.484813,56057.6%43.8%
61.64%736.794614,73365.6%58.5%
57.14%716.379812,82557.5%56.7%
57.81%641.45729,83762.5%53.1%
52.54%596.185413,31351.9%53.1%
50.85%591.45929,76145.2%57.1%
43.10%585.275112,01441.4%44.8%
50.88%571.459010,77147.8%52.9%
50.91%552.060611,82263.2%44.4%
52.94%526.073413,14541.7%63.0%
57.69%526.782914,53356.5%58.6%
53.33%466.281113,20847.6%58.3%
43.90%411.453910,99738.5%46.4%
64.71%346.879013,30362.5%66.7%
52.94%342.158411,28140.0%58.3%
57.58%336.077412,36447.1%68.8%
54.55%331.743710,00852.6%57.1%
48.48%336.279614,62660.0%43.5%
35.48%311.45879,61526.3%50.0%
66.67%305.878012,89861.5%70.6%
55.17%291.959311,39846.1%62.5%
55.17%291.555310,69461.5%50.0%
57.14%281.55629,79162.5%50.0%
46.15%271.250810,03854.5%40.0%
51.85%273.255211,44946.7%58.3%
54.17%241.859710,04846.1%63.6%
60.87%246.386213,25776.9%40.0%
38.10%214.075910,65045.5%30.0%
61.90%215.872113,73975.0%53.9%
45.00%202.068211,39033.3%50.0%
35.00%202.352310,97142.9%30.8%
43.75%161.547610,65737.5%50.0%
26.67%151.44849,99628.6%25.0%
60.00%151.460111,15860.0%60.0%
61.54%145.88708,97662.5%60.0%
78.57%141.65119,73866.7%87.5%
69.23%141.575612,70875.0%66.7%
61.54%132.077110,95725.0%77.8%
61.54%135.884812,19233.3%85.7%
41.67%122.754310,4990.0%71.4%
41.67%124.682910,50942.9%40.0%
54.55%112.57159,55660.0%50.0%
36.36%112.867710,14737.5%33.3%
54.55%111.34499,09580.0%33.3%
70.00%103.471011,39580.0%60.0%
60.00%101.54989,52540.0%80.0%
66.67%92.06079,56283.3%33.3%
25.00%93.66749,35920.0%33.3%
33.33%93.264510,22325.0%40.0%
75.00%83.461510,46766.7%80.0%
42.86%73.859911,5460.0%50.0%
42.86%75.587114,3990.0%60.0%
42.86%75.065111,61133.3%50.0%
28.57%73.885711,21533.3%25.0%
57.14%72.470610,064100.0%0.0%
42.86%75.561911,56566.7%25.0%
100.00%72.965911,106100.0%100.0%
28.57%72.755310,5070.0%40.0%
50.00%63.754511,45750.0%50.0%
16.67%65.51,02011,9340.0%25.0%
50.00%65.71,03613,566100.0%40.0%
50.00%62.84489,75566.7%33.3%
83.33%64.376510,567100.0%50.0%
50.00%65.489612,44850.0%50.0%
33.33%64.36017,73525.0%50.0%
50.00%63.564410,66833.3%66.7%
83.33%64.51,04711,47066.7%100.0%
50.00%63.51,24113,5610.0%60.0%
66.67%65.298716,0320.0%66.7%
40.00%56.387911,52433.3%50.0%
100.00%52.668411,590100.0%100.0%
60.00%52.95538,75750.0%66.7%
60.00%51.267712,19150.0%66.7%
100.00%54.252813,697100.0%100.0%
60.00%55.475012,67866.7%50.0%
60.00%54.554011,238100.0%50.0%
40.00%52.87499,0390.0%66.7%
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Senna vs Miss Fortune - Frequently Asked Questions

How does Senna do against Miss Fortune in League of Legends?

Senna wins the Senna vs Miss Fortune matchup with a 54.4% win rate compared to Miss Fortune's 45.6%, a 8.9 percentage point difference. This data is based on 170 recent ranked games in patch 26.4.

How does Senna do against Miss Fortune in the early game?

In the early game, Senna has the advantage against Miss Fortune with a 54.5% win rate versus 45.5%. Senna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Senna do against Miss Fortune in the late game?

In the late game, Senna takes over the Senna vs Miss Fortune matchup with a 54.4% win rate compared to 45.6%. Senna scales better into team fights and objective contests after 25 minutes.

Who wins the Senna vs Miss Fortune matchup?

Senna wins the matchup against Miss Fortune with a 54.4% win rate in League of Legends patch 26.4. The 8.9 percentage point advantage means Senna is significantly favored in this lane matchup based on 170 games analyzed.

What is the best Senna build against Miss Fortune?

The best Senna build against Miss Fortune includes Dawncore, Moonstone Renewer, Black Cleaver with Boots of Swiftness. Check the matchup breakdown above for the full item path and build order.

What are the best Senna runes against Miss Fortune?

The best Senna runes against Miss Fortune use the Precision primary tree with Sorcery secondary. This rune setup achieves a 63.6% win rate in the Senna vs Miss Fortune matchup. See the full rune breakdown in the matchup comparison above.

Does Senna counter Miss Fortune?

Yes, Senna has a favorable matchup against Miss Fortune with a 54.4% win rate. Senna strongly counters Miss Fortune in lane based on current patch 26.4 data.

How do I play Senna against Miss Fortune?

When playing Senna against Miss Fortune, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.