Seraphine, League of Legends champion
Win Rate
0%
Pick Rate
0%
Ban Rate
15.1%

Seraphine ADC Runes: Keystone & Shards

SupportMage
Patch
26.20
Matches
2,058,390
Lane
Bot
Tier
All Tiers
Last Updated
Oct 18, 2026 UTC
Methodology
Data Methodology

Best Bot Seraphine runes for LoL Patch 26.20 - Keystone from the Primary tree with Secondary secondary (0% WR, 0% pick rate). Seraphine's optimal primary runes are {primaryRunes}. Secondary tree: {secondaryRunes}.

Seraphine performs best with Keystone as the keystone rune from the Primary tree. Seraphine's optimal primary runes are . Seraphine's secondary rune tree is Secondary with . This rune setup achieves a 0% win rate (NaN% win rate difference) with a 0% pick rate across 0 Seraphine games.

Primary Tree

 rune tree icon

Secondary Tree

 rune tree icon
%Win Rate
NaN%WR Diff
%Pick Rate
This alternative Seraphine rune build uses Alternative Keystone as the keystone from the Primary tree. The primary runes are . Seraphine's secondary rune tree is Secondary with . This setup achieves a 0% win rate (NaN% win rate difference) with a 0% pick rate across 0 games.

Primary Tree

 rune tree icon

Secondary Tree

 rune tree icon
%Win Rate
NaN%WR Diff
%Pick Rate

Every Seraphine Bot Keystone and Secondary Tree (Patch 26.20)

519 games

Seraphine Bot runs Arcane Comet in 71% of games, with a 48.6% win rate. Precision is the usual secondary tree (42%). Standard stat shards: Ability Haste (offense), Adaptive Force (flex), Health (defense).

Keystones

RunePlayersWin RateGames
Arcane CometArcane CometMost played70.5%48.6%366
Summon AerySummon Aery14.1%47.9%73

Secondary trees

RunePlayersWin RateGames
PrecisionPrecisionMost played42.4%48.2%220
InspirationInspiration35.6%48.6%185
ResolveResolve8.5%52.3%44

Pick rate is the share of Seraphine games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.

Seraphine Minor Runes by Tree

Every minor rune Seraphine players take, grouped by rune tree, with how often it is picked and how often it wins.

Sorcery

RunePlayersWin RateGames
Manaflow BandManaflow BandMost played90.4%48.8%469
TranscendenceTranscendence86.3%48.0%448
ScorchScorch50.3%49.4%261
Gathering StormGathering Storm43.5%49.1%226

Precision

RunePlayersWin RateGames
Legend: HasteLegend: HasteMost played32.8%46.5%170
Cut DownCut Down25.8%50.0%134
Presence of MindPresence of Mind17.5%49.5%91
Coup de GraceCoup de Grace8.9%56.5%46

Inspiration

RunePlayersWin RateGames
Cosmic InsightCosmic InsightMost played32.8%49.4%170
Biscuit DeliveryBiscuit Delivery29.7%49.4%154

Domination

RunePlayersWin RateGames
Ultimate HunterUltimate HunterMost played15.8%54.9%82
Cheap ShotCheap Shot14.6%57.9%76

Resolve

RunePlayersWin RateGames
RevitalizeRevitalizeMost played8.1%50.0%42

Seraphine Stat Shards

Which stat shards Seraphine players choose in each of the three shard rows, and the win rate of each.

RunePlayersWin RateGames
Adaptive Force (flex)Adaptive Force (flex)Most played94.6%49.7%491
Health (defense)Health (defense)75.3%49.4%391
Ability Haste (offense)Ability Haste (offense)73.0%48.5%379
Adaptive Force (offense)Adaptive Force (offense)18.9%54.1%98
Health Scaling (defense)Health Scaling (defense)18.9%45.9%98
Attack Speed (offense)Attack Speed (offense)8.1%45.2%42
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Seraphine Runes FAQ - Patch 26.20

What is the best keystone for Seraphine Bot?

Arcane Comet: Seraphine Bot takes it in 71% of ranked games and wins 48.6% of 366 games. Alternatives: Summon Aery (14%, 47.9%).

What stat shards should Seraphine take?

Most Seraphine players take Ability Haste (offense), Adaptive Force (flex), Health (defense) — one from each shard row.

What are the best Seraphine runes in patch 26.20?

The best Seraphine runes in patch 26.20 use the Primary tree with , and the Secondary tree with . This rune setup achieves a 0% win rate with a 0% pick rate.

What is the win rate for Seraphine's best rune page?

Seraphine's best rune page has a 0% win rate in patch 26.20, which is NaN% compared to Seraphine's average win rate. This rune setup has a 0% pick rate among Seraphine players.

What keystone should I use on Seraphine?

your chosen keystone from the Primary tree is the best keystone rune for Seraphine in patch 26.20. This keystone synergizes well with Seraphine's kit and provides a 0% win rate.

What is Seraphine's primary rune tree?

Seraphine's primary rune tree is Primary. The optimal Primary runes for Seraphine are , with your chosen keystone being the keystone of choice.

What is Seraphine's secondary rune tree?

Seraphine's best secondary rune tree is Secondary. The recommended Secondary runes are , which complement Seraphine's Primary primary tree.

What are alternative rune setups for Seraphine?

An alternative Seraphine rune setup uses alternative keystone from the Primary tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Seraphine's runes?

Seraphine's top rune page has a 0% pick rate in patch 26.20. This indicates that 0% of Seraphine players use the your chosen keystone setup with Primary and Secondary trees.