Syndra - League of Legends Champion
Win Rate
50.0%
Pick Rate
1.8%

Syndravs Cassiopeia

CMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 7, 2026
MethodologyData Methodology

Syndra vs Cassiopeia is a decisive matchup in LoL patch 26.11. Syndra wins with a 52.6% win rate (+5.3%) over Cassiopeia based on 19 games. Syndra holds the advantage in both the early and late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Cassiopeia matchup.

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Syndra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra - 52.6% win rate in this matchup
Syndra
52.6% WR
VS
Cassiopeia vs Syndra matchup - 47.4% win rate
Cassiopeia
47.4% WR

Who Wins the Syndra vs Cassiopeia Matchup?

Syndra wins the Syndra vs Cassiopeia matchup
Winner
Syndra
Matches: 19
52.6%
Win Rate
47.4%
6.9
CS / min
6.4
850
DMG / min
749
11,392
Gold / game
10,423
84
Heal / min
292
334
DMG Mitigated / min
569
1.5
CC / min
1.0
55.6%
Early Game WR
44.4%
50.0%
Late Game WR
50.0%

Syndra vs Cassiopeia Matchup Summary

The Syndra vs Cassiopeia matchup is a moderate matchup in League of Legends ranked play. Based on 19 recent matches analyzed, Syndra wins with a 52.6% win rate compared to Cassiopeia's 47.4%, giving Syndra a 5.3 percentage point advantage. Syndra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Cassiopeia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Cassiopeia leads by 443 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a statistical edge, but the margin is close enough that respecting Cassiopeia's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Syndra vs Cassiopeia Laning Phase Breakdown

Syndra wins the laning phase against Cassiopeia in League of Legends

Syndra is favored during the laning phase against Cassiopeia, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.9Syndra
6.4Cassiopeia
Syndra edges out Cassiopeia by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.
Damage
850Syndra
749Cassiopeia
Syndra heavily out-damages Cassiopeia by 101 DMG/min, dominating both short trades and all-in fights. Cassiopeia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
11,392Syndra
10,423Cassiopeia
Syndra generates a commanding 969 more gold per game than Cassiopeia. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Cassiopeia should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.5Syndra
1.0Cassiopeia
Syndra provides 0.4 seconds more crowd control per minute than Cassiopeia, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Syndra coordinate with their jungler and control the pace of skirmishes.
Sustain
418Syndra
860Cassiopeia
Cassiopeia vastly out-sustains Syndra, healing and mitigating 443 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Syndra Build Against Cassiopeia

Spellslinger's Shoes is the optimal boots choice against Cassiopeia, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Cassiopeia are Luden's Echo, Stormsurge and Shadowflame. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 4 games, proving it to be a reliable item path when facing Cassiopeia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Cassiopeia matchup.

Early Game vs Late Game

Early Game
Syndra
55.6%
+11.1% advantage
Syndra early game win rateSyndra55.6%
Cassiopeia early game win rateCassiopeia44.4%
Late Game
Syndra
50.0%
+0.0% advantage
Syndra late game win rateSyndra50.0%
Cassiopeia late game win rateCassiopeia50.0%

Syndra dominates the early game (first 15 minutes) with a commanding 55.6% win rate — a 11.1 percentage point lead over Cassiopeia. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Syndra at 50.0% win rate — only 0.0 points ahead of Cassiopeia. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

Syndra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Cassiopeia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Syndra Runes Against Cassiopeia

Domination rune tree - Syndra primary runes vs CassiopeiaDomination
Electrocute - best Syndra rune vs CassiopeiaTaste of Blood - best Syndra rune vs CassiopeiaGrisly Mementos - best Syndra rune vs CassiopeiaUltimate Hunter - best Syndra rune vs Cassiopeia
Sorcery rune tree - Syndra secondary runes vs CassiopeiaSorcery
Manaflow Band - best Syndra rune vs CassiopeiaTranscendence - best Syndra rune vs Cassiopeia
100.0% WR

Running Domination primary with Sorcery secondary allows Syndra to press their advantage against Cassiopeia, amplifying the strengths that make this a favorable matchup.


Syndra matchup data for League of Legends patch 26.11. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Syndra matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
50.63%1607.092512,95556.9%46.3%
59.85%1327.187812,44254.2%64.4%
50.56%896.997413,64854.3%48.1%
41.67%846.278711,91626.7%50.0%
49.40%836.782512,19937.8%58.7%
51.81%836.797612,54648.7%54.5%
39.02%826.680411,94945.7%34.0%
43.75%806.890112,69137.8%48.8%
43.59%787.090612,66957.1%32.6%
61.76%686.991812,26162.5%61.1%
49.23%656.379811,83433.3%60.5%
47.54%616.588111,37955.6%41.2%
49.15%596.793413,36840.0%53.9%
45.61%577.090212,70645.5%45.7%
58.93%567.082512,22266.7%51.7%
46.43%567.084811,90164.3%28.6%
51.85%546.995413,53242.9%57.6%
51.85%546.185411,14248.1%55.6%
52.83%536.91,03113,55563.2%47.1%
36.00%506.985212,06139.1%33.3%
55.10%496.683311,77152.0%58.3%
61.36%447.31,01214,21560.0%62.1%
51.16%437.085311,76336.4%66.7%
50.00%426.91,06012,40755.6%45.8%
42.86%426.587212,20838.1%47.6%
51.35%376.985113,27045.5%53.9%
45.95%377.092412,02058.8%35.0%
43.24%377.093612,65323.1%54.2%
61.11%366.892813,03286.7%42.9%
44.12%346.181210,96647.4%40.0%
40.63%327.296110,69037.5%43.8%
41.94%316.494812,72645.5%40.0%
58.06%316.91,00512,25753.9%61.1%
37.93%296.599213,62933.3%41.2%
50.00%286.788112,43042.9%57.1%
53.85%267.181112,20950.0%58.3%
62.50%246.586111,13244.4%73.3%
47.83%237.01,02313,10755.6%42.9%
56.52%236.91,06713,93242.9%62.5%
45.45%226.195712,69916.7%56.3%
70.00%207.199212,88860.0%80.0%
47.37%196.494414,49750.0%47.1%
52.63%196.985011,39255.6%50.0%
55.56%187.076912,60360.0%50.0%
58.82%177.091413,90060.0%58.3%
47.06%177.289913,79240.0%57.1%
58.82%177.31,10611,86150.0%66.7%
50.00%166.483910,69688.9%0.0%
43.75%166.988012,31355.6%28.6%
56.25%165.796214,12580.0%45.5%
66.67%157.483811,60550.0%77.8%
69.23%134.893512,62466.7%71.4%
46.15%136.982512,89342.9%50.0%
75.00%127.390713,00360.0%85.7%
36.36%116.984712,91116.7%60.0%
30.00%106.880312,09920.0%40.0%
70.00%107.188313,14380.0%60.0%
60.00%106.984410,84180.0%40.0%
44.44%97.41,05911,62650.0%33.3%
77.78%96.88168,89985.7%50.0%
77.78%97.11,04714,21166.7%83.3%
50.00%87.486013,71233.3%60.0%
37.50%87.578611,74533.3%50.0%
25.00%87.27849,92233.3%0.0%
50.00%83.484411,28175.0%25.0%
50.00%87.395912,25350.0%50.0%
14.29%77.283510,85020.0%0.0%
28.57%75.767210,49133.3%25.0%
85.71%75.71,06116,911100.0%83.3%
42.86%76.81,12013,9920.0%60.0%
85.71%77.295515,01275.0%100.0%
28.57%77.41,06815,19650.0%20.0%
28.57%77.31,07211,51150.0%0.0%
33.33%65.91,00612,02833.3%33.3%
33.33%66.26499,09233.3%33.3%
66.67%67.01,14114,55366.7%66.7%
66.67%65.889012,39866.7%66.7%
33.33%67.01,18515,5440.0%50.0%
20.00%57.697312,39633.3%0.0%
60.00%56.976210,79366.7%50.0%
60.00%56.81,00415,0500.0%75.0%
60.00%57.490914,314100.0%33.3%
80.00%57.51,26514,545100.0%75.0%
40.00%54.289712,08533.3%50.0%
20.00%57.11,16210,6240.0%50.0%

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Syndra vs Cassiopeia - Frequently Asked Questions

How does Syndra do against Cassiopeia in League of Legends?

Syndra wins the Syndra vs Cassiopeia matchup with a 52.6% win rate compared to Cassiopeia's 47.4%, a 5.3 percentage point difference. This data is based on 19 recent ranked games in patch 26.11.

How does Syndra do against Cassiopeia in the early game?

In the early game, Syndra has the advantage against Cassiopeia with a 55.6% win rate versus 44.4%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Syndra do against Cassiopeia in the late game?

In the late game, Syndra takes over the Syndra vs Cassiopeia matchup with a 50.0% win rate compared to 50.0%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Syndra vs Cassiopeia matchup?

Syndra wins the matchup against Cassiopeia with a 52.6% win rate in League of Legends patch 26.11. The 5.3 percentage point advantage means Syndra is significantly favored in this lane matchup based on 19 games analyzed.

What is the best Syndra build against Cassiopeia?

The best Syndra build against Cassiopeia includes Luden's Echo, Stormsurge, Shadowflame with Spellslinger's Shoes. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Syndra runes against Cassiopeia?

The best Syndra runes against Cassiopeia use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Syndra vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.

Does Syndra counter Cassiopeia?

Yes, Syndra has a favorable matchup against Cassiopeia with a 52.6% win rate. Syndra strongly counters Cassiopeia in lane based on current patch 26.11 data.

How do I play Syndra against Cassiopeia?

When playing Syndra against Cassiopeia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.