Syndra, League of Legends champion
Win Rate
50.3%
Pick Rate
4.1%
Ban Rate
9.5%

Syndra vs Cassiopeia

Syndra B TierMage
Patch
26.22
Games
8,013
Lane
All Lanes
Tier
All Tiers
Last Updated
Nov 14, 2026 UTC
Methodology
Data Methodology

Syndra vs Cassiopeia (Mid): Syndra wins 48.2% of 83 ranked games over the last 2 patches (gold diff at 15: -37). Patch 26.22 build & runes.

Syndra – League of Legends champion iconSyndra48.2%
No clear favoriteLow confidence · 83 games · Patch 26.21–26.22
51.8%CassiopeiaCassiopeia – League of Legends champion icon

Current data slightly favors Cassiopeia, but the sample is too limited for a strong conclusion: Syndra wins 48.2% of 83 games (95% range 37.8–58.8%).

Syndra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra – League of Legends champion icon
Syndra
48.2%
VS
Cassiopeia
51.8%
Cassiopeia – League of Legends champion icon

Who wins Syndra vs Cassiopeia?

No clear favoriteLow confidence

Syndra wins 48.2% of these games. With this many games the true rate is most likely between 37.8% and 58.8% (95% range).

Expected
52.7%
From both champions' overall Mid win rates
Matchup effect
−4.5 pts
Observed minus expected
Sample
83 games
Lane: Mid · Patch 26.21–26.22
vs patch 26.21
—
Not enough games on both patches

Lane: Mid · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.21–26.22 · Oct 27 – Nov 13

The headline win rate covers patches 26.21–26.22 (83 games). The lane, game-length, build and rune sections below use patch 26.22 only (63 games).

Key takeaways

  • Current data slightly favors Cassiopeia, but the sample is too limited for a strong conclusion: Syndra wins 48.2% of 83 games (95% range 37.8–58.8%).
  • Both champions' overall Mid win rates predict 52.7% for Syndra; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
  • Neither side reliably wins the lane: the average gold difference at 15 minutes is 37, within the margin of error (62 games).
  • Syndra players pick Luden's Echo much less often against Cassiopeia: 51.2% of their other Mid games, 34.9% here.
How we calculate this

Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.

A game only counts when Syndra and Cassiopeia played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.

The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.

Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.

"What changes" compares Syndra's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).

Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.

Syndra vs Cassiopeia Laning Stats

SyndraCassiopeia

At 15 minutes

Gold difference
−37
Within the margin of error
95% range −386 to +312
XP difference
−202
Within the margin of error
95% range −526 to +121
CS difference
−0.5
Within the margin of error
95% range −7.0 to +6.0
2.15
Kills before 15 min
2.40
2.37
Deaths before 15 min
2.05
0.57
Solo kills before 15 min
0.59
6.3%
First blood
6.3%

Whole-game averages

7.4
CS / min
7.1
949
DMG / min
762
12,432
Gold / game
11,622
76
Heal / min
283
311
DMG Mitigated / min
542
1.4
CC / min
1.0

Syndra vs Cassiopeia Win Rate by Game Length

Syndra's win rate against Cassiopeia by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.

Too few games
Under 20 min
6 games
Too few games
20–25 min
7 games
Too few games
25–30 min
21 games
Too few games
30–35 min
18 games
Too few games
35+ min
11 games
Syndra vs Cassiopeia95% rangeSyndra usual (Mid)

No game length stands out: Syndra's results against Cassiopeia in short and long games are within the margin of error of each other.

Syndra vs Cassiopeia Power Spikes

Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.

  1. Lane (15 min)EvenSyndra gold at 15: −37
  2. First itemEvenSyndra: 11.8 min · Cassiopeia: 11.5 min
  3. Games under 20 minInsufficient data
  4. 20–30 min gamesInsufficient data
  5. 30+ min gamesInsufficient data

What Syndra Changes Against Cassiopeia

Choices Syndra players make noticeably more or less often in this matchup than in their other Mid games.

  • Luden's Echo – League of Legends item
    Usually
    51.2%
    vs Cassiopeia
    34.9%
    −16.3 pts59.1% WR here
  • Blackfire Torch – League of Legends item
    Usually
    43.3%
    vs Cassiopeia
    57.1%
    +13.9 pts38.9% WR here
  • Flash – League of Legends summoner spellTeleport – League of Legends summoner spell
    Flash + TeleportSummoner spells
    Usually
    86.3%
    vs Cassiopeia
    95.2%
    +9.0 pts45.0% WR here
  • Swiftmarch – League of Legends item
    Usually
    5.0%
    vs Cassiopeia
    11.1%
    +6.1 pts
  • Horizon Focus – League of Legends item
    Usually
    under 0.5%
    vs Cassiopeia
    3.2%
    +3.2 pts

Best Syndra Build vs Cassiopeia

Usual Syndra build (Mid)

86.2% win rate · 29 games

Against Cassiopeia

Not enough matchup-specific build data: only 7 of 38 Syndra games against Cassiopeia carried a complete build, which is too few to recommend an item path from. Use Syndra's standard build instead.

  • Syndra usually completes Blackfire Torch first, at 11.8 min (median of 35 games).
  • Cassiopeia usually completes Rod of Ages first, at 11.5 min (median of 46 games).
  • Skill priority: Q > W > E — the same as usual.

Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.

Best Syndra Runes vs Cassiopeia

Usual Syndra runes (Mid)

First Strike – League of Legends runeFirst Strike
Inspiration
Magical Footwear – League of Legends runeBiscuit Delivery – League of Legends runeCosmic Insight – League of Legends rune
Sorcery
Manaflow Band – League of Legends runeTranscendence – League of Legends rune
Attack Speed (offense) – League of Legends runeAdaptive Force (flex) – League of Legends runeHealth Scaling (defense) – League of Legends rune

50.7% win rate · 946 games

Against Cassiopeia

Too few games for a matchup-specific rune page yet — use the usual page.

MetaBot Desktop

Plan your Syndra draft in Draft Lab

Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.

  • Full 5v5 draft board
  • Lane matchup win rates
  • Pick and ban suggestions
Draft Lab in MetaBot Desktop

Syndra matchup data for League of Legends patch 26.22. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Other Syndra Matchups

Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.

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Syndra vs Cassiopeia FAQ - Patch 26.21–26.22

Who wins Syndra vs Cassiopeia?

Current data slightly favors Cassiopeia, but the sample is too limited for a strong conclusion: Syndra wins 48.2% of 83 games (95% range 37.8–58.8%).

What is Syndra's win rate against Cassiopeia?

Syndra wins 48.2% of 83 Mid games against Cassiopeia on patch 26.21–26.22 (95% range 37.8–58.8%). Based on both champions' overall Mid win rates, 52.7% would be expected.

Does Syndra counter Cassiopeia?

Not clearly. Syndra wins 48.2% of 83 games against Cassiopeia, and the 95% range (37.8–58.8%) includes 50%, so neither champion reliably counters the other on current data.

Who wins lane, Syndra or Cassiopeia?

Neither side reliably wins the lane: the average gold difference at 15 minutes is 37, within the margin of error (62 games).

Does Syndra outscale Cassiopeia?

There are too few games of each length to tell yet.

When is Cassiopeia strongest against Syndra?

On current data there is no stage of the game where Cassiopeia is ahead of Syndra beyond the margin of error.

What should Syndra build against Cassiopeia?

There are not enough games for a matchup-specific core, so use Syndra's usual Mid core: Luden's Echo, Shadowflame, Mejai's Soulstealer. The biggest change against Cassiopeia: Luden's Echo (51.2% usually, 34.9% here).

What runes should Syndra use against Cassiopeia?

Use Syndra's usual First Strike page (Inspiration + Sorcery); there are too few games for a matchup-specific page. The biggest change against Cassiopeia: Flash + Teleport (86.3% usually, 95.2% here).