Syndra - League of Legends Champion
Win Rate
50.4%
Pick Rate
2.2%

Syndravs Cassiopeia

BMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 22, 2026
MethodologyData Methodology

Syndra vs Cassiopeia is a decisive matchup in LoL patch 26.7. Syndra wins with a 53.9% win rate (+7.7%) over Cassiopeia based on 13 games. Syndra wins the early laning phase while Cassiopeia scales better into the late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Cassiopeia matchup.

Syndra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Cassiopeia - 53.9% win rateCassiopeia(53.9%)
Syndra - 53.9% win rate in this matchup
Syndra
53.9% WR
VS
Cassiopeia vs Syndra matchup - 46.1% win rate
Cassiopeia
46.1% WR

Who Wins the Syndra vs Cassiopeia Matchup?

Syndra wins the Syndra vs Cassiopeia matchup
Winner
Syndra
Matches: 13
53.9%
Win Rate
46.1%
7.1
CS / min
6.8
876
DMG / min
691
10,649
Gold / game
9,869
71
Heal / min
240
328
DMG Mitigated / min
526
1.2
CC / min
1.0
62.5%
Early Game WR
37.5%
40.0%
Late Game WR
60.0%

Syndra vs Cassiopeia Matchup Summary

The Syndra vs Cassiopeia matchup is a decisive matchup in League of Legends ranked play. Based on 13 recent matches analyzed, Syndra wins with a 53.9% win rate compared to Cassiopeia's 46.1%, giving Syndra a 7.7 percentage point advantage. Game phase dynamics play a critical role here: Syndra controls the early laning stage, but Cassiopeia outscales as the game goes longer. The matchup shifts dramatically depending on game length — Syndra needs to press advantages before Cassiopeia reaches their power spikes, while Cassiopeia should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Cassiopeia leads by 367 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra players can confidently pick into Cassiopeia and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Cassiopeia away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Syndra vs Cassiopeia Laning Phase Breakdown

Syndra wins the laning phase against Cassiopeia in League of Legends

Syndra is favored during the laning phase against Cassiopeia, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
7.1Syndra
6.8Cassiopeia
Syndra edges out Cassiopeia by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.
Damage
876Syndra
691Cassiopeia
Syndra heavily out-damages Cassiopeia by 185 DMG/min, dominating both short trades and all-in fights. Cassiopeia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
10,649Syndra
9,869Cassiopeia
Syndra earns 780 more gold per game than Cassiopeia, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Syndra slightly faster item completions.
Utility
1.2Syndra
1.0Cassiopeia
Both Syndra and Cassiopeia provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
399Syndra
766Cassiopeia
Cassiopeia vastly out-sustains Syndra, healing and mitigating 367 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Syndra Build Against Cassiopeia

Spellslinger's Shoes is the optimal boots choice against Cassiopeia, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Cassiopeia are Luden's Echo, Shadowflame and Zhonya's Hourglass. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Cassiopeia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Cassiopeia matchup.

Early Game vs Late Game

Early Game
Syndra
62.5%
+25.0% advantage
Syndra early game win rateSyndra62.5%
Cassiopeia early game win rateCassiopeia37.5%
Late Game
Cassiopeia
60.0%
+20.0% advantage
Syndra late game win rateSyndra40.0%
Cassiopeia late game win rateCassiopeia60.0%

Syndra dominates the early game (first 15 minutes) with a commanding 62.5% win rate — a 25.0 percentage point lead over Cassiopeia. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Cassiopeia is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Syndra. Extended games heavily favor Cassiopeia, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Syndra must aggressively press their early advantage and close out the game before Cassiopeia reaches their scaling breakpoints. If Cassiopeia survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Syndra Runes Against Cassiopeia

Sorcery rune tree - Syndra primary runes vs CassiopeiaSorcery
Summon Aery - best Syndra rune vs CassiopeiaManaflow Band - best Syndra rune vs CassiopeiaTranscendence - best Syndra rune vs CassiopeiaScorch - best Syndra rune vs Cassiopeia
Inspiration rune tree - Syndra secondary runes vs CassiopeiaInspiration
Biscuit Delivery - best Syndra rune vs CassiopeiaCosmic Insight - best Syndra rune vs Cassiopeia
100.0% WR

Running Sorcery primary with Inspiration secondary allows Syndra to press their advantage against Cassiopeia, amplifying the strengths that make this a favorable matchup.


Syndra matchup data for League of Legends patch 26.7. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Syndra matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
55.04%1297.393112,75149.2%60.3%
46.07%897.091912,96650.0%43.6%
50.00%846.885111,63640.0%59.1%
51.85%817.290913,13051.3%52.4%
52.56%787.384812,64655.6%50.0%
45.83%727.080813,01541.9%48.8%
44.78%676.479211,52944.8%44.7%
62.07%586.799613,99473.9%54.3%
50.00%546.992112,08943.3%58.3%
39.22%517.088613,35433.3%43.3%
40.82%496.674711,69523.8%53.6%
54.35%467.291112,93255.0%53.9%
48.84%436.780412,39344.4%52.0%
42.86%426.983511,61942.1%43.5%
59.52%427.086612,85426.7%77.8%
64.29%426.978811,43565.2%63.2%
52.38%427.095212,82152.6%52.2%
43.90%416.587011,26045.0%42.9%
47.50%406.999613,60450.0%45.8%
52.50%407.095113,76650.0%53.9%
55.56%367.080112,03360.0%45.5%
52.78%367.01,02013,39542.9%59.1%
47.22%366.882410,06640.9%57.1%
37.14%357.081310,77134.8%41.7%
54.55%337.291513,64766.7%47.6%
65.63%327.01,07214,11163.6%66.7%
58.06%317.41,02513,88564.7%50.0%
51.61%317.01,01113,79260.0%43.8%
37.93%296.980212,04841.7%35.3%
55.17%297.089312,26573.3%35.7%
60.00%257.187712,74645.5%71.4%
39.13%237.284011,86833.3%50.0%
61.90%217.31,01812,21066.7%58.3%
25.00%207.090211,53822.2%27.3%
40.00%207.692513,00642.9%38.5%
52.63%197.01,02813,4750.0%71.4%
55.56%186.998712,65533.3%66.7%
55.56%186.585012,49842.9%63.6%
70.59%177.81,20513,80077.8%62.5%
47.06%177.297513,92437.5%55.6%
56.25%167.796215,264100.0%36.4%
43.75%166.687113,10120.0%54.5%
62.50%167.296914,00777.8%42.9%
60.00%157.687813,43662.5%57.1%
60.00%156.986613,97880.0%50.0%
64.29%147.394113,07666.7%62.5%
50.00%146.889613,06783.3%25.0%
38.46%137.21,02312,79842.9%33.3%
53.85%137.187610,64962.5%40.0%
61.54%137.088414,04166.7%57.1%
50.00%127.194611,92566.7%33.3%
66.67%127.183612,79262.5%75.0%
55.56%96.899115,7870.0%71.4%
33.33%97.399211,99928.6%50.0%
37.50%86.81,03812,80040.0%33.3%
57.14%77.689013,21050.0%66.7%
42.86%75.881910,10640.0%50.0%
42.86%76.71,01311,89233.3%50.0%
66.67%67.08819,08450.0%100.0%
50.00%67.91,08615,078100.0%40.0%
83.33%65.790914,734100.0%80.0%
50.00%66.694412,37333.3%66.7%
50.00%67.082911,19750.0%50.0%
83.33%66.51,08015,590100.0%75.0%
66.67%67.71,03716,00250.0%75.0%
0.00%57.690213,6370.0%0.0%
80.00%56.484513,566100.0%66.7%
60.00%57.51,03214,08233.3%100.0%
60.00%57.395612,89766.7%50.0%
60.00%52.485211,91450.0%66.7%
40.00%57.069511,8570.0%66.7%

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Syndra vs Cassiopeia - Frequently Asked Questions

How does Syndra do against Cassiopeia in League of Legends?

Syndra wins the Syndra vs Cassiopeia matchup with a 53.9% win rate compared to Cassiopeia's 46.1%, a 7.7 percentage point difference. This data is based on 13 recent ranked games in patch 26.7.

How does Syndra do against Cassiopeia in the early game?

In the early game, Syndra has the advantage against Cassiopeia with a 62.5% win rate versus 37.5%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Syndra do against Cassiopeia in the late game?

In the late game, Cassiopeia takes over the Syndra vs Cassiopeia matchup with a 60.0% win rate compared to 40.0%. Cassiopeia scales better into team fights and objective contests after 25 minutes.

Who wins the Syndra vs Cassiopeia matchup?

Syndra wins the matchup against Cassiopeia with a 53.9% win rate in League of Legends patch 26.7. The 7.7 percentage point advantage means Syndra is significantly favored in this lane matchup based on 13 games analyzed.

What is the best Syndra build against Cassiopeia?

The best Syndra build against Cassiopeia includes Luden's Echo, Shadowflame, Zhonya's Hourglass with Spellslinger's Shoes. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Syndra runes against Cassiopeia?

The best Syndra runes against Cassiopeia use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Syndra vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.

Does Syndra counter Cassiopeia?

Yes, Syndra has a favorable matchup against Cassiopeia with a 53.9% win rate. Syndra strongly counters Cassiopeia in lane based on current patch 26.7 data.

How do I play Syndra against Cassiopeia?

When playing Syndra against Cassiopeia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.