Cassiopeia - League of Legends Champion
Win Rate
49.7%
Pick Rate
0.9%

Cassiopeiavs Syndra

CMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 21, 2026
MethodologyData Methodology

Cassiopeia vs Syndra is a decisive matchup in LoL patch 26.7. Syndra wins with a 53.9% win rate (+7.7%) over Cassiopeia based on 13 games. Syndra wins the early laning phase while Cassiopeia scales better into the late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Syndra matchup.

Cassiopeia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra - 46.1% win rateSyndra(46.1%)
Cassiopeia - 46.1% win rate in this matchup
Cassiopeia
46.1% WR
VS
Syndra vs Cassiopeia matchup - 53.9% win rate
Syndra
53.9% WR

Who Wins the Cassiopeia vs Syndra Matchup?

Syndra wins the Cassiopeia vs Syndra matchup
Winner
Syndra
Matches: 13
46.1%
Win Rate
53.9%
6.8
CS / min
7.1
691
DMG / min
876
9,869
Gold / game
10,649
240
Heal / min
71
526
DMG Mitigated / min
328
1.0
CC / min
1.2
37.5%
Early Game WR
62.5%
60.0%
Late Game WR
40.0%

Cassiopeia vs Syndra Matchup Summary

The Cassiopeia vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 13 recent matches analyzed, Syndra wins with a 53.9% win rate compared to Cassiopeia's 46.1%, giving Syndra a 7.7 percentage point advantage. Game phase dynamics play a critical role here: Syndra controls the early laning stage, but Cassiopeia outscales as the game goes longer. The matchup shifts dramatically depending on game length — Syndra needs to press advantages before Cassiopeia reaches their power spikes, while Cassiopeia should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Cassiopeia leads by 367 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a strong advantage in this matchup. Cassiopeia players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Syndra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Cassiopeia vs Syndra Laning Phase Breakdown

Syndra wins the laning phase against Cassiopeia in League of Legends

Syndra is favored during the laning phase against Cassiopeia, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.8Cassiopeia
7.1Syndra
Syndra edges out Cassiopeia by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.
Damage
691Cassiopeia
876Syndra
Syndra heavily out-damages Cassiopeia by 185 DMG/min, dominating both short trades and all-in fights. Cassiopeia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
9,869Cassiopeia
10,649Syndra
Syndra earns 780 more gold per game than Cassiopeia, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Syndra slightly faster item completions.
Utility
1.0Cassiopeia
1.2Syndra
Both Cassiopeia and Syndra provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
766Cassiopeia
399Syndra
Cassiopeia vastly out-sustains Syndra, healing and mitigating 367 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Cassiopeia Build Against Syndra

Swiftmarch is the optimal boots choice against Syndra, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Syndra are Liandry's Torment, Rabadon's Deathcap and Seraph's Embrace. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Syndra matchup.

Early Game vs Late Game

Early Game
Syndra
62.5%
+25.0% advantage
Cassiopeia early game win rateCassiopeia37.5%
Syndra early game win rateSyndra62.5%
Late Game
Cassiopeia
60.0%
+20.0% advantage
Cassiopeia late game win rateCassiopeia60.0%
Syndra late game win rateSyndra40.0%

Syndra dominates the early game (first 15 minutes) with a commanding 62.5% win rate — a 25.0 percentage point lead over Cassiopeia. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Cassiopeia is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Syndra. Extended games heavily favor Cassiopeia, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Syndra must aggressively press their early advantage and close out the game before Cassiopeia reaches their scaling breakpoints. If Cassiopeia survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Cassiopeia Runes Against Syndra

Sorcery rune tree - Cassiopeia primary runes vs SyndraSorcery
Arcane Comet - best Cassiopeia rune vs SyndraManaflow Band - best Cassiopeia rune vs SyndraCelerity - best Cassiopeia rune vs SyndraScorch - best Cassiopeia rune vs Syndra
Precision rune tree - Cassiopeia secondary runes vs SyndraPrecision
Presence of Mind - best Cassiopeia rune vs SyndraLegend: Haste - best Cassiopeia rune vs Syndra
100.0% WR

The Sorcery and Precision rune setup gives Cassiopeia the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Cassiopeia matchup data for League of Legends patch 26.7. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Cassiopeia matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
56.25%326.788512,08850.0%66.7%
55.17%297.082911,66350.0%60.0%
48.00%256.776712,31650.0%47.4%
47.83%236.872911,51240.0%62.5%
45.45%226.385913,06120.0%52.9%
59.09%226.484912,54862.5%57.1%
42.11%196.986411,12127.3%62.5%
42.11%196.590810,89433.3%57.1%
57.89%196.492112,99228.6%75.0%
41.18%176.373912,06537.5%44.4%
35.29%176.773611,49814.3%50.0%
58.82%177.076110,08961.5%50.0%
43.75%166.579312,56433.3%46.1%
37.50%166.679911,96633.3%40.0%
37.50%166.769211,33728.6%44.4%
66.67%156.194812,98175.0%63.6%
66.67%157.098013,675100.0%54.5%
50.00%146.580411,93333.3%62.5%
57.14%146.565011,06250.0%62.5%
21.43%146.485812,88566.7%9.1%
46.15%136.86919,86937.5%60.0%
69.23%136.494011,61866.7%71.4%
58.33%126.984013,60150.0%66.7%
66.67%126.91,01711,75950.0%83.3%
36.36%116.262311,14260.0%16.7%
81.82%116.894211,31971.4%100.0%
54.55%116.593013,22360.0%50.0%
63.64%117.46599,84555.6%100.0%
36.36%115.583012,70025.0%42.9%
45.45%116.71,09012,21225.0%57.1%
45.45%117.179011,95850.0%42.9%
40.00%106.483613,98333.3%42.9%
20.00%107.565811,9420.0%25.0%
77.78%97.093011,929100.0%60.0%
44.44%96.11,06214,147100.0%37.5%
33.33%96.374010,38820.0%50.0%
62.50%86.293212,07075.0%50.0%
50.00%86.584011,20660.0%33.3%
62.50%87.21,06913,95450.0%66.7%
37.50%87.375311,9870.0%60.0%
62.50%86.580412,10040.0%100.0%
71.43%76.71,07712,31650.0%80.0%
42.86%76.61,02513,52950.0%40.0%
57.14%76.282511,09066.7%50.0%
28.57%76.479313,23650.0%0.0%
85.71%77.097012,450100.0%75.0%
83.33%66.864110,21075.0%100.0%
33.33%66.575210,28925.0%50.0%
83.33%66.784013,44550.0%100.0%
33.33%66.875810,81125.0%50.0%
66.67%65.987214,875100.0%60.0%
16.67%66.155810,7760.0%50.0%
83.33%66.986213,632100.0%50.0%
60.00%57.190515,4910.0%75.0%
0.00%56.91,07312,4530.0%0.0%
60.00%57.31,07713,11466.7%50.0%
80.00%56.999912,801100.0%50.0%
40.00%56.783410,90933.3%50.0%
20.00%55.77549,53133.3%0.0%
80.00%57.079611,09275.0%100.0%
40.00%56.774513,361100.0%0.0%
80.00%57.26758,508100.0%50.0%
60.00%55.91,14416,9190.0%60.0%
60.00%56.77329,347100.0%0.0%
20.00%56.895411,16633.3%0.0%

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Cassiopeia vs Syndra - Frequently Asked Questions

How does Cassiopeia do against Syndra in League of Legends?

Syndra wins the Cassiopeia vs Syndra matchup with a 53.9% win rate compared to Cassiopeia's 46.1%, a 7.7 percentage point difference. This data is based on 13 recent ranked games in patch 26.7.

How does Cassiopeia do against Syndra in the early game?

In the early game, Syndra has the advantage against Cassiopeia with a 62.5% win rate versus 37.5%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Cassiopeia do against Syndra in the late game?

In the late game, Cassiopeia takes over the Cassiopeia vs Syndra matchup with a 60.0% win rate compared to 40.0%. Cassiopeia scales better into team fights and objective contests after 25 minutes.

Who wins the Cassiopeia vs Syndra matchup?

Syndra wins the matchup against Cassiopeia with a 53.9% win rate in League of Legends patch 26.7. The 7.7 percentage point advantage means Syndra is significantly favored in this lane matchup based on 13 games analyzed.

What is the best Cassiopeia build against Syndra?

The best Cassiopeia build against Syndra includes Liandry's Torment, Rabadon's Deathcap, Seraph's Embrace with Swiftmarch. Check the matchup breakdown above for the full item path and build order.

What are the best Cassiopeia runes against Syndra?

The best Cassiopeia runes against Syndra use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Cassiopeia counter Syndra?

No, Cassiopeia struggles against Syndra with only a 46.1% win rate. Syndra has the advantage in this matchup. Cassiopeia players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.

How do I play Cassiopeia against Syndra?

When playing Cassiopeia against Syndra, play cautiously and avoid Syndra's power spikes. Focus on safe farming — you outscale Syndra in the late game. Use the matchup-specific build and runes above to optimize your chances.