
Cassiopeiavs Syndra
Cassiopeia vs Syndra is a decisive matchup in LoL patch 26.11. Syndra wins with a 52.6% win rate (+5.3%) over Cassiopeia based on 19 games. Syndra wins the early laning phase while Cassiopeia scales better into the late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Syndra matchup.
Cassiopeia Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Cassiopeia vs Syndra Matchup?

Cassiopeia vs Syndra Matchup Summary
The Cassiopeia vs Syndra matchup is a moderate matchup in League of Legends ranked play. Based on 19 recent matches analyzed, Syndra wins with a 52.6% win rate compared to Cassiopeia's 47.4%, giving Syndra a 5.3 percentage point advantage. Game phase dynamics play a critical role here: Syndra controls the early laning stage, but Cassiopeia outscales as the game goes longer. The matchup shifts dramatically depending on game length — Syndra needs to press advantages before Cassiopeia reaches their power spikes, while Cassiopeia should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Cassiopeia leads by 443 HP/min — a difference that heavily influences the outcome of trades and skirmishes. While Syndra is slightly favored, Cassiopeia can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Syndra's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Cassiopeia vs Syndra Laning Phase Breakdown
Syndra is favored during the laning phase against Cassiopeia, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Cassiopeia Build Against Syndra
Immortal Path is the optimal boots choice against Syndra, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Syndra are Rod of Ages, Rylai's Crystal Scepter and Seraph's Embrace. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 4 games, proving it to be a reliable item path when facing Syndra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Syndra matchup.
Early Game vs Late Game
Syndra dominates the early game (first 15 minutes) with a commanding 55.6% win rate — a 11.1 percentage point lead over Cassiopeia. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Late game (25+ minutes) is equally balanced, with Cassiopeia at 50.0% win rate — only 0.0 points ahead of Syndra. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
The power dynamics shift as the game progresses — Syndra has the edge early, but Cassiopeia gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Cassiopeia Runes Against Syndra
The Sorcery and Resolve rune setup gives Cassiopeia the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Cassiopeia matchup data for League of Legends patch 26.11. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 47.54% | 61 | 6.3 | 835 | 12,011 | 64.0% | 36.1% | |
| 52.17% | 46 | 6.8 | 913 | 12,152 | 52.6% | 51.9% | |
| 48.65% | 37 | 6.7 | 894 | 10,720 | 47.4% | 50.0% | |
| 45.45% | 33 | 6.5 | 776 | 11,981 | 38.5% | 50.0% | |
| 46.88% | 32 | 6.6 | 858 | 10,851 | 38.1% | 63.6% | |
| 45.16% | 31 | 6.3 | 812 | 10,571 | 40.0% | 50.0% | |
| 51.61% | 31 | 7.1 | 968 | 10,348 | 54.5% | 44.4% | |
| 45.16% | 31 | 5.9 | 771 | 12,569 | 60.0% | 38.1% | |
| 64.52% | 31 | 6.7 | 921 | 11,762 | 66.7% | 62.5% | |
| 62.07% | 29 | 6.7 | 843 | 12,319 | 53.3% | 71.4% | |
| 42.86% | 28 | 6.9 | 740 | 11,662 | 42.9% | 42.9% | |
| 65.22% | 23 | 6.1 | 884 | 11,047 | 70.0% | 61.5% | |
| 34.78% | 23 | 6.1 | 787 | 10,814 | 40.0% | 30.8% | |
| 34.78% | 23 | 6.2 | 741 | 10,910 | 40.0% | 30.8% | |
| 31.82% | 22 | 6.5 | 811 | 12,229 | 50.0% | 21.4% | |
| 47.62% | 21 | 6.6 | 669 | 9,969 | 27.3% | 70.0% | |
| 66.67% | 21 | 7.0 | 956 | 12,822 | 80.0% | 62.5% | |
| 66.67% | 21 | 5.7 | 771 | 11,603 | 50.0% | 76.9% | |
| 60.00% | 20 | 6.8 | 724 | 11,518 | 50.0% | 70.0% | |
| 47.37% | 19 | 6.4 | 749 | 10,423 | 44.4% | 50.0% | |
| 63.16% | 19 | 6.4 | 893 | 11,549 | 70.0% | 55.6% | |
| 58.82% | 17 | 6.8 | 858 | 11,943 | 60.0% | 57.1% | |
| 52.94% | 17 | 6.5 | 925 | 11,500 | 37.5% | 66.7% | |
| 52.94% | 17 | 6.8 | 774 | 10,920 | 50.0% | 55.6% | |
| 82.35% | 17 | 6.7 | 891 | 11,594 | 88.9% | 75.0% | |
| 47.06% | 17 | 6.0 | 864 | 12,190 | 33.3% | 54.5% | |
| 37.50% | 16 | 6.6 | 882 | 12,072 | 40.0% | 36.4% | |
| 33.33% | 15 | 6.7 | 835 | 12,460 | 0.0% | 45.5% | |
| 66.67% | 15 | 5.7 | 815 | 12,128 | 50.0% | 77.8% | |
| 50.00% | 14 | 5.5 | 793 | 9,648 | 40.0% | 55.6% | |
| 71.43% | 14 | 6.6 | 718 | 11,583 | 80.0% | 66.7% | |
| 57.14% | 14 | 6.6 | 888 | 8,746 | 77.8% | 20.0% | |
| 42.86% | 14 | 7.0 | 965 | 13,939 | 66.7% | 25.0% | |
| 61.54% | 13 | 6.6 | 944 | 13,076 | 40.0% | 75.0% | |
| 33.33% | 12 | 7.3 | 910 | 10,994 | 40.0% | 28.6% | |
| 41.67% | 12 | 6.4 | 1,040 | 12,890 | 60.0% | 28.6% | |
| 33.33% | 12 | 6.6 | 791 | 13,559 | 100.0% | 27.3% | |
| 45.45% | 11 | 6.7 | 746 | 11,841 | 25.0% | 57.1% | |
| 18.18% | 11 | 6.2 | 786 | 12,089 | 0.0% | 28.6% | |
| 45.45% | 11 | 6.0 | 850 | 11,825 | 50.0% | 42.9% | |
| 63.64% | 11 | 5.7 | 903 | 13,107 | 66.7% | 62.5% | |
| 27.27% | 11 | 6.4 | 746 | 11,720 | 20.0% | 33.3% | |
| 36.36% | 11 | 6.5 | 960 | 14,270 | 50.0% | 28.6% | |
| 20.00% | 10 | 6.6 | 726 | 10,424 | 28.6% | 0.0% | |
| 40.00% | 10 | 6.3 | 984 | 14,522 | 50.0% | 37.5% | |
| 11.11% | 9 | 6.3 | 653 | 8,764 | 20.0% | 0.0% | |
| 44.44% | 9 | 6.9 | 872 | 11,904 | 40.0% | 50.0% | |
| 33.33% | 9 | 6.3 | 724 | 12,713 | 66.7% | 16.7% | |
| 44.44% | 9 | 6.4 | 1,278 | 12,869 | 50.0% | 42.9% | |
| 55.56% | 9 | 6.4 | 776 | 11,325 | 50.0% | 60.0% | |
| 55.56% | 9 | 6.5 | 887 | 12,685 | 0.0% | 62.5% | |
| 66.67% | 9 | 6.4 | 937 | 14,897 | 100.0% | 57.1% | |
| 25.00% | 8 | 7.3 | 802 | 13,090 | 33.3% | 20.0% | |
| 37.50% | 8 | 6.5 | 843 | 12,217 | 33.3% | 40.0% | |
| 57.14% | 7 | 5.9 | 892 | 12,356 | 66.7% | 50.0% | |
| 28.57% | 7 | 7.2 | 924 | 14,448 | 0.0% | 33.3% | |
| 42.86% | 7 | 6.2 | 771 | 11,594 | 50.0% | 33.3% | |
| 14.29% | 7 | 6.8 | 916 | 11,035 | 0.0% | 25.0% | |
| 71.43% | 7 | 6.0 | 860 | 11,651 | 100.0% | 50.0% | |
| 28.57% | 7 | 5.9 | 738 | 8,495 | 33.3% | 0.0% | |
| 66.67% | 6 | 6.5 | 926 | 13,985 | 0.0% | 100.0% | |
| 66.67% | 6 | 6.8 | 873 | 13,102 | 100.0% | 50.0% | |
| 33.33% | 6 | 6.8 | 635 | 10,697 | 50.0% | 25.0% | |
| 50.00% | 6 | 6.2 | 765 | 12,039 | 66.7% | 33.3% | |
| 50.00% | 6 | 6.7 | 653 | 10,177 | 66.7% | 33.3% | |
| 50.00% | 6 | 6.5 | 998 | 12,680 | 100.0% | 25.0% | |
| 60.00% | 5 | 6.3 | 675 | 11,352 | 50.0% | 66.7% | |
| 40.00% | 5 | 7.4 | 1,034 | 13,862 | 50.0% | 33.3% | |
| 20.00% | 5 | 8.1 | 765 | 11,226 | 33.3% | 0.0% | |
| 40.00% | 5 | 6.0 | 1,365 | 11,712 | 50.0% | 33.3% | |
| 40.00% | 5 | 5.8 | 725 | 8,657 | 100.0% | 25.0% | |
| 80.00% | 5 | 5.5 | 684 | 10,127 | 100.0% | 50.0% | |
| 20.00% | 5 | 7.3 | 1,044 | 10,500 | 33.3% | 0.0% | |
| 80.00% | 5 | 6.9 | 879 | 10,244 | 100.0% | 66.7% | |
| 20.00% | 5 | 6.2 | 783 | 9,079 | 50.0% | 0.0% | |
| 60.00% | 5 | 7.8 | 896 | 13,847 | 100.0% | 50.0% | |
| 40.00% | 5 | 5.0 | 714 | 11,229 | 0.0% | 50.0% | |
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Cassiopeia vs Syndra - Frequently Asked Questions
How does Cassiopeia do against Syndra in League of Legends?
Syndra wins the Cassiopeia vs Syndra matchup with a 52.6% win rate compared to Cassiopeia's 47.4%, a 5.3 percentage point difference. This data is based on 19 recent ranked games in patch 26.11.
How does Cassiopeia do against Syndra in the early game?
In the early game, Syndra has the advantage against Cassiopeia with a 55.6% win rate versus 44.4%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Cassiopeia do against Syndra in the late game?
In the late game, Cassiopeia takes over the Cassiopeia vs Syndra matchup with a 50.0% win rate compared to 50.0%. Cassiopeia scales better into team fights and objective contests after 25 minutes.
Who wins the Cassiopeia vs Syndra matchup?
Syndra wins the matchup against Cassiopeia with a 52.6% win rate in League of Legends patch 26.11. The 5.3 percentage point advantage means Syndra is significantly favored in this lane matchup based on 19 games analyzed.
What is the best Cassiopeia build against Syndra?
The best Cassiopeia build against Syndra includes Rod of Ages, Rylai's Crystal Scepter, Seraph's Embrace with Immortal Path. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Cassiopeia runes against Syndra?
The best Cassiopeia runes against Syndra use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Syndra matchup. See the full rune breakdown in the matchup comparison above.
Does Cassiopeia counter Syndra?
No, Cassiopeia struggles against Syndra with only a 47.4% win rate. Syndra has the advantage in this matchup. Cassiopeia players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.
How do I play Cassiopeia against Syndra?
When playing Cassiopeia against Syndra, play cautiously and avoid Syndra's power spikes. Focus on safe farming — you outscale Syndra in the late game. Use the matchup-specific build and runes above to optimize your chances.
