Syndra - League of Legends Champion
Win Rate
52.3%
Pick Rate
2.9%

Syndravs Karma

SMage
Patch26.3
Matches785,220
LaneAll Lanes
TierAll Tiers
Last UpdatedFeb 24, 2026
MethodologyData Methodology

Syndra vs Karma is a decisive matchup in LoL patch 26.3. Karma wins with a 62.5% win rate (+25.0%) over Syndra based on 8 games. Syndra wins the early laning phase while Karma scales better into the late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Karma matchup.

Syndra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karma - 37.5% win rateKarma(37.5%)
Syndra - 37.5% win rate in this matchup
Syndra
37.5% WR
VS
Karma vs Syndra matchup - 62.5% win rate
Karma
62.5% WR

Who Wins the Syndra vs Karma Matchup?

Karma wins the Syndra vs Karma matchup
Winner
Karma
Matches: 8
37.5%
Win Rate
62.5%
5.5
CS / min
5.1
778
DMG / min
620
13,354
Gold / game
12,076
77
Heal / min
240
351
DMG Mitigated / min
758
1.4
CC / min
0.9
100.0%
Early Game WR
0.0%
16.7%
Late Game WR
83.3%

Syndra vs Karma Matchup Summary

The Syndra vs Karma matchup is a decisive matchup in League of Legends ranked play. Based on 8 recent matches analyzed, Karma wins with a 62.5% win rate compared to Syndra's 37.5%, giving Karma a 25.0 percentage point advantage. Game phase dynamics play a critical role here: Syndra controls the early laning stage, but Karma outscales as the game goes longer. The matchup shifts dramatically depending on game length — Syndra needs to press advantages before Karma reaches their power spikes, while Karma should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Karma leads by 570 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Karma has a strong advantage in this matchup. Syndra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karma overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Syndra vs Karma Laning Phase Breakdown

Syndra wins the laning phase against Karma in League of Legends

Syndra is favored during the laning phase against Karma, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
5.5Syndra
5.1Karma
Syndra edges out Karma by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.
Damage
778Syndra
620Karma
Syndra heavily out-damages Karma by 159 DMG/min, dominating both short trades and all-in fights. Karma should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
13,354Syndra
12,076Karma
Syndra generates a commanding 1,278 more gold per game than Karma. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karma should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.4Syndra
0.9Karma
Syndra provides 0.5 seconds more crowd control per minute than Karma, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Syndra coordinate with their jungler and control the pace of skirmishes.
Sustain
428Syndra
998Karma
Karma vastly out-sustains Syndra, healing and mitigating 570 more damage per minute. This massive durability gap means Karma can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Syndra Build Against Karma

Crimson Lucidity is the optimal boots choice against Karma, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Karma are Luden's Echo, Shadowflame and Zhonya's Hourglass. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Karma matchup.

Early Game vs Late Game

Early Game
Syndra
100.0%
+100.0% advantage
Syndra early game win rateSyndra100.0%
Karma early game win rateKarma0.0%
Late Game
Karma
83.3%
+66.7% advantage
Syndra late game win rateSyndra16.7%
Karma late game win rateKarma83.3%

Syndra dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Karma. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karma is far superior in the late game (25+ minutes), boasting a 83.3% win rate — 66.7 points above Syndra. Extended games heavily favor Karma, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Syndra must aggressively press their early advantage and close out the game before Karma reaches their scaling breakpoints. If Karma survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Syndra Runes Against Karma

Domination rune tree - Syndra primary runes vs KarmaDomination
Electrocute - best Syndra rune vs KarmaTaste of Blood - best Syndra rune vs KarmaGrisly Mementos - best Syndra rune vs KarmaUltimate Hunter - best Syndra rune vs Karma
Sorcery rune tree - Syndra secondary runes vs KarmaSorcery
Manaflow Band - best Syndra rune vs KarmaTranscendence - best Syndra rune vs Karma
100.0% WR

The Domination and Sorcery rune setup gives Syndra the best tools to compete against Karma in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Syndra matchup data for League of Legends patch 26.3. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Syndra matchup win rates and stats in League of Legends patch 26.3
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
50.59%2537.195613,30848.3%52.5%
53.97%1897.084513,00852.6%55.0%
51.85%1897.298013,43458.4%47.3%
44.74%1527.185612,91043.8%45.5%
55.15%1367.190813,12248.3%60.3%
44.92%1186.781112,88443.5%45.8%
51.72%1166.682312,09143.1%58.5%
52.17%1156.779912,12637.5%66.1%
46.02%1136.680112,10442.9%48.4%
50.89%1127.297913,06851.0%50.8%
41.67%1086.789812,97332.5%47.1%
65.05%1037.499512,79760.8%69.2%
44.55%1016.882212,08943.1%46.0%
44.68%947.294613,39952.4%38.5%
45.65%926.882412,24947.7%43.8%
48.24%857.185612,67647.5%48.9%
49.41%856.986712,96248.6%50.0%
53.57%847.393212,77156.8%50.0%
57.83%837.092413,25654.3%60.4%
54.32%816.689912,81462.9%47.8%
45.00%806.682312,26647.4%42.9%
51.90%797.295611,87050.0%53.9%
67.61%716.790213,28070.4%65.9%
57.75%716.691512,78353.6%60.5%
58.46%657.096413,62565.2%54.8%
43.75%646.988712,20053.3%35.3%
55.74%616.890813,59472.2%48.8%
61.67%606.81,06214,17558.8%62.8%
59.32%596.895212,88066.7%54.3%
61.02%597.190512,71161.5%60.6%
50.00%587.096412,57641.4%58.6%
53.45%587.081510,79458.5%41.2%
50.88%576.984113,10357.9%47.4%
54.55%556.997713,71666.7%48.6%
50.00%467.392712,98450.0%50.0%
61.36%447.41,05914,10768.8%57.1%
47.37%386.596513,35452.9%42.9%
55.56%367.091214,16069.2%47.8%
45.16%317.11,07113,74954.5%40.0%
53.33%307.094313,41954.5%52.6%
57.14%286.994313,70160.0%55.6%
50.00%266.973111,36336.4%60.0%
57.69%267.81,01412,95475.0%42.9%
40.00%256.91,01814,01955.6%31.3%
66.67%246.693312,47866.7%66.7%
50.00%227.31,14913,48838.5%66.7%
61.90%217.189412,74263.6%60.0%
71.43%217.51,17014,15690.9%50.0%
50.00%207.41,16916,02271.4%38.5%
47.37%197.989913,61962.5%36.4%
61.11%186.81,04314,80450.0%66.7%
52.94%176.593814,73666.7%45.5%
47.06%176.798014,12371.4%30.0%
62.50%167.376813,26350.0%75.0%
53.33%157.71,02614,33887.5%14.3%
64.29%146.997714,81666.7%63.6%
78.57%146.696812,35466.7%100.0%
76.92%136.981211,84766.7%85.7%
23.08%137.086012,00628.6%16.7%
66.67%126.51,01513,02771.4%60.0%
58.33%127.270711,91080.0%42.9%
41.67%126.293012,42316.7%66.7%
45.45%115.873511,24180.0%16.7%
54.55%116.61,1349,85457.1%50.0%
54.55%116.391015,4830.0%60.0%
27.27%117.497513,2380.0%37.5%
63.64%117.883310,63683.3%40.0%
50.00%106.01,00913,51566.7%42.9%
40.00%107.51,13011,92325.0%100.0%
70.00%106.81,25214,17183.3%50.0%
30.00%107.41,07316,7470.0%33.3%
66.67%97.21,14913,82260.0%75.0%
55.56%92.278611,347100.0%42.9%
75.00%86.789813,724100.0%50.0%
50.00%86.51,05713,8510.0%57.1%
50.00%87.898213,46233.3%60.0%
0.00%86.882611,4060.0%0.0%
37.50%85.577813,354100.0%16.7%
50.00%86.91,23714,9900.0%66.7%
12.50%87.588712,66225.0%0.0%
37.50%87.095312,48466.7%20.0%
85.71%77.51,16613,00580.0%100.0%
42.86%76.21,00012,8690.0%50.0%
57.14%76.194211,63850.0%60.0%
71.43%73.66729,16975.0%66.7%
42.86%77.087015,5980.0%50.0%
71.43%76.91,02914,504100.0%50.0%
83.33%67.11,24616,036100.0%80.0%
66.67%67.277512,55066.7%66.7%
33.33%67.386510,28040.0%0.0%
50.00%66.41,19212,00866.7%33.3%
83.33%66.81,09212,32450.0%100.0%
60.00%57.11,05315,496100.0%33.3%
60.00%56.896611,952100.0%50.0%
40.00%57.181914,886100.0%0.0%
60.00%56.894813,75766.7%50.0%
60.00%56.881411,49150.0%66.7%
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Syndra vs Karma - Frequently Asked Questions

How does Syndra do against Karma in League of Legends?

Karma wins the Syndra vs Karma matchup with a 62.5% win rate compared to Syndra's 37.5%, a 25.0 percentage point difference. This data is based on 8 recent ranked games in patch 26.3.

How does Syndra do against Karma in the early game?

In the early game, Syndra has the advantage against Karma with a 100.0% win rate versus 0.0%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Syndra do against Karma in the late game?

In the late game, Karma takes over the Syndra vs Karma matchup with a 83.3% win rate compared to 16.7%. Karma scales better into team fights and objective contests after 25 minutes.

Who wins the Syndra vs Karma matchup?

Karma wins the matchup against Syndra with a 62.5% win rate in League of Legends patch 26.3. The 25.0 percentage point advantage means Karma is significantly favored in this lane matchup based on 8 games analyzed.

What is the best Syndra build against Karma?

The best Syndra build against Karma includes Luden's Echo, Shadowflame, Zhonya's Hourglass with Crimson Lucidity. Check the matchup breakdown above for the full item path and build order.

What are the best Syndra runes against Karma?

The best Syndra runes against Karma use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Syndra vs Karma matchup. See the full rune breakdown in the matchup comparison above.

Does Syndra counter Karma?

No, Syndra struggles against Karma with only a 37.5% win rate. Karma has the advantage in this matchup. Syndra players should focus on safe farming and avoiding extended trades to minimize Karma's lead.

How do I play Syndra against Karma?

When playing Syndra against Karma, play cautiously and avoid Karma's power spikes. Look for jungle assistance and team-dependent plays since Karma has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.