Syndravs Karthus
Syndra vs Karthus is a decisive matchup in LoL patch 26.10. Syndra wins with a 66.7% win rate (+33.3%) over Karthus based on 6 games. Karthus wins the early laning phase while Syndra scales better into the late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Karthus matchup.
Syndra Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Karthus(66.7%)Who Wins the Syndra vs Karthus Matchup?
Syndra vs Karthus Matchup Summary
The Syndra vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Syndra wins with a 66.7% win rate compared to Karthus's 33.3%, giving Syndra a 33.3 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Syndra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Syndra reaches their power spikes, while Syndra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Syndra leads by 0.9s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra players can confidently pick into Karthus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Karthus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Syndra vs Karthus Laning Phase Breakdown
Syndra is favored during the laning phase against Karthus, winning 5 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.
Best Syndra Build Against Karthus
Crimson Lucidity is the optimal boots choice against Karthus, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Karthus are Cosmic Drive, Cryptbloom and Rabadon's Deathcap. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Karthus matchup.
Early Game vs Late Game
Syndra33.3%Karthus66.7%Syndra100.0%Karthus0.0%Karthus dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Syndra. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Syndra is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Karthus. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Syndra reaches their scaling breakpoints. If Syndra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Syndra Runes Against Karthus
Inspiration
Sorcery
Running Inspiration primary with Sorcery secondary allows Syndra to press their advantage against Karthus, amplifying the strengths that make this a favorable matchup.
Syndra matchup data for League of Legends patch 26.10. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 50.54% | 184 | 7.2 | 926 | 12,706 | 44.9% | 54.7% | |
| 51.45% | 138 | 7.0 | 881 | 12,741 | 54.1% | 49.4% | |
| 51.47% | 136 | 6.7 | 855 | 12,074 | 50.9% | 51.9% | |
| 45.00% | 120 | 6.6 | 862 | 12,342 | 39.5% | 47.6% | |
| 55.08% | 118 | 7.2 | 907 | 12,793 | 56.0% | 54.4% | |
| 51.79% | 112 | 6.6 | 826 | 12,301 | 43.8% | 57.8% | |
| 43.24% | 111 | 6.9 | 1,006 | 13,771 | 43.8% | 43.0% | |
| 55.88% | 102 | 6.7 | 869 | 11,786 | 50.0% | 60.3% | |
| 45.26% | 95 | 6.5 | 865 | 11,400 | 44.4% | 46.0% | |
| 42.39% | 92 | 6.7 | 767 | 11,305 | 43.2% | 41.7% | |
| 59.76% | 82 | 6.9 | 962 | 11,676 | 73.2% | 46.3% | |
| 35.00% | 80 | 6.8 | 814 | 12,028 | 26.3% | 42.9% | |
| 51.28% | 78 | 6.8 | 852 | 12,333 | 62.5% | 43.5% | |
| 38.03% | 71 | 6.7 | 912 | 12,227 | 39.3% | 37.2% | |
| 47.89% | 71 | 6.5 | 917 | 11,958 | 31.3% | 61.5% | |
| 52.86% | 70 | 6.6 | 789 | 11,944 | 44.0% | 57.8% | |
| 48.48% | 66 | 7.0 | 792 | 11,319 | 52.9% | 43.8% | |
| 56.92% | 65 | 6.7 | 908 | 11,961 | 58.6% | 55.6% | |
| 46.77% | 62 | 6.5 | 890 | 12,285 | 53.6% | 41.2% | |
| 54.24% | 59 | 6.8 | 849 | 11,000 | 53.6% | 54.8% | |
| 57.14% | 56 | 7.1 | 938 | 12,992 | 80.0% | 44.4% | |
| 50.00% | 56 | 6.6 | 1,017 | 13,883 | 68.2% | 38.2% | |
| 52.94% | 51 | 7.0 | 905 | 11,240 | 56.0% | 50.0% | |
| 49.02% | 51 | 6.9 | 899 | 12,926 | 47.6% | 50.0% | |
| 60.00% | 50 | 7.0 | 872 | 12,295 | 54.5% | 64.3% | |
| 51.02% | 49 | 7.0 | 959 | 13,288 | 42.1% | 56.7% | |
| 56.25% | 48 | 7.4 | 970 | 12,909 | 59.1% | 53.9% | |
| 58.33% | 48 | 6.8 | 870 | 11,234 | 60.9% | 56.0% | |
| 45.65% | 46 | 6.5 | 784 | 11,889 | 40.0% | 50.0% | |
| 57.78% | 45 | 6.5 | 985 | 13,234 | 42.9% | 64.5% | |
| 68.29% | 41 | 6.7 | 979 | 13,064 | 50.0% | 77.8% | |
| 42.50% | 40 | 6.4 | 950 | 11,459 | 35.0% | 50.0% | |
| 68.42% | 38 | 7.0 | 1,041 | 14,267 | 73.3% | 65.2% | |
| 58.82% | 34 | 7.2 | 995 | 13,767 | 80.0% | 50.0% | |
| 36.36% | 33 | 7.4 | 859 | 13,025 | 50.0% | 26.3% | |
| 58.06% | 31 | 6.4 | 835 | 11,772 | 53.3% | 62.5% | |
| 51.61% | 31 | 7.2 | 1,062 | 12,945 | 40.0% | 62.5% | |
| 41.38% | 29 | 7.0 | 935 | 13,176 | 50.0% | 35.3% | |
| 55.17% | 29 | 6.8 | 845 | 13,232 | 70.0% | 47.4% | |
| 46.43% | 28 | 6.8 | 1,138 | 13,800 | 50.0% | 45.0% | |
| 36.00% | 25 | 6.8 | 1,028 | 12,529 | 55.6% | 25.0% | |
| 64.00% | 25 | 7.0 | 969 | 14,098 | 60.0% | 66.7% | |
| 33.33% | 24 | 6.8 | 867 | 13,727 | 40.0% | 31.6% | |
| 47.83% | 23 | 7.0 | 899 | 12,867 | 42.9% | 50.0% | |
| 56.52% | 23 | 7.0 | 1,044 | 14,519 | 44.4% | 64.3% | |
| 34.78% | 23 | 6.4 | 908 | 12,340 | 20.0% | 38.9% | |
| 40.91% | 22 | 6.7 | 1,013 | 12,214 | 23.1% | 66.7% | |
| 36.36% | 22 | 5.5 | 968 | 11,578 | 44.4% | 30.8% | |
| 45.00% | 20 | 7.1 | 1,017 | 13,038 | 50.0% | 41.7% | |
| 36.84% | 19 | 7.1 | 977 | 13,581 | 37.5% | 36.4% | |
| 47.06% | 17 | 6.9 | 886 | 12,480 | 66.7% | 36.4% | |
| 52.94% | 17 | 6.9 | 1,012 | 13,904 | 85.7% | 30.0% | |
| 43.75% | 16 | 5.8 | 894 | 14,513 | 50.0% | 41.7% | |
| 33.33% | 15 | 6.4 | 862 | 11,695 | 14.3% | 50.0% | |
| 40.00% | 15 | 7.2 | 860 | 13,451 | 28.6% | 50.0% | |
| 66.67% | 15 | 6.4 | 964 | 13,078 | 80.0% | 60.0% | |
| 40.00% | 15 | 7.3 | 786 | 10,715 | 33.3% | 50.0% | |
| 71.43% | 14 | 7.2 | 1,057 | 14,725 | 66.7% | 72.7% | |
| 46.15% | 13 | 7.0 | 909 | 10,515 | 42.9% | 50.0% | |
| 25.00% | 12 | 7.4 | 892 | 13,101 | 20.0% | 28.6% | |
| 50.00% | 12 | 6.5 | 902 | 12,279 | 40.0% | 57.1% | |
| 72.73% | 11 | 5.8 | 1,152 | 13,413 | 75.0% | 71.4% | |
| 81.82% | 11 | 6.7 | 859 | 13,209 | 100.0% | 71.4% | |
| 60.00% | 10 | 5.8 | 847 | 12,064 | 25.0% | 83.3% | |
| 60.00% | 10 | 7.4 | 755 | 12,651 | 40.0% | 80.0% | |
| 40.00% | 10 | 7.1 | 1,145 | 12,965 | 0.0% | 57.1% | |
| 70.00% | 10 | 7.7 | 1,013 | 14,075 | 25.0% | 100.0% | |
| 44.44% | 9 | 6.8 | 1,154 | 14,941 | 25.0% | 60.0% | |
| 62.50% | 8 | 7.2 | 1,139 | 12,956 | 33.3% | 80.0% | |
| 62.50% | 8 | 3.5 | 798 | 10,484 | 66.7% | 60.0% | |
| 62.50% | 8 | 7.0 | 1,026 | 12,386 | 66.7% | 60.0% | |
| 57.14% | 7 | 6.8 | 805 | 12,148 | 50.0% | 60.0% | |
| 14.29% | 7 | 6.4 | 761 | 10,088 | 0.0% | 20.0% | |
| 57.14% | 7 | 6.8 | 1,000 | 12,262 | 33.3% | 75.0% | |
| 42.86% | 7 | 7.4 | 886 | 12,978 | 33.3% | 50.0% | |
| 42.86% | 7 | 6.0 | 869 | 11,606 | 50.0% | 33.3% | |
| 50.00% | 6 | 3.6 | 1,013 | 13,110 | 50.0% | 50.0% | |
| 66.67% | 6 | 6.2 | 889 | 13,780 | 0.0% | 80.0% | |
| 66.67% | 6 | 7.8 | 1,200 | 11,634 | 33.3% | 100.0% | |
| 40.00% | 5 | 6.0 | 874 | 15,638 | 100.0% | 25.0% | |
| 60.00% | 5 | 6.9 | 812 | 11,194 | 100.0% | 50.0% | |
| 80.00% | 5 | 7.1 | 1,120 | 12,768 | 66.7% | 100.0% | |
| 40.00% | 5 | 3.3 | 691 | 7,864 | 40.0% | 0.0% | |
| 40.00% | 5 | 7.3 | 794 | 12,879 | 50.0% | 33.3% | |
| 60.00% | 5 | 7.3 | 1,046 | 14,029 | 100.0% | 50.0% | |
| 20.00% | 5 | 1.8 | 680 | 9,636 | 33.3% | 0.0% | |
| 60.00% | 5 | 3.0 | 1,003 | 10,514 | 100.0% | 33.3% | |
| 60.00% | 5 | 7.7 | 1,025 | 16,411 | 66.7% | 50.0% | |
| 80.00% | 5 | 7.2 | 1,191 | 13,547 | 100.0% | 66.7% | |
| 60.00% | 5 | 6.4 | 823 | 10,583 | 33.3% | 100.0% | |
| 60.00% | 5 | 7.5 | 1,009 | 19,277 | 0.0% | 60.0% | |
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Syndra vs Karthus - Frequently Asked Questions
How does Syndra do against Karthus in League of Legends?
Syndra wins the Syndra vs Karthus matchup with a 66.7% win rate compared to Karthus's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.10.
How does Syndra do against Karthus in the early game?
In the early game, Karthus has the advantage against Syndra with a 66.7% win rate versus 33.3%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Syndra do against Karthus in the late game?
In the late game, Syndra takes over the Syndra vs Karthus matchup with a 100.0% win rate compared to 0.0%. Syndra scales better into team fights and objective contests after 25 minutes.
Who wins the Syndra vs Karthus matchup?
Syndra wins the matchup against Karthus with a 66.7% win rate in League of Legends patch 26.10. The 33.3 percentage point advantage means Syndra is significantly favored in this lane matchup based on 6 games analyzed.
What is the best Syndra build against Karthus?
The best Syndra build against Karthus includes Cosmic Drive, Cryptbloom, Rabadon's Deathcap with Crimson Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Syndra runes against Karthus?
The best Syndra runes against Karthus use the Inspiration primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Syndra vs Karthus matchup. See the full rune breakdown in the matchup comparison above.
Does Syndra counter Karthus?
Yes, Syndra has a favorable matchup against Karthus with a 66.7% win rate. Syndra strongly counters Karthus in lane based on current patch 26.10 data.
How do I play Syndra against Karthus?
When playing Syndra against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Karthus. Build the recommended items and runes for this specific matchup for the best results.