Win Rate
50.6%
Pick Rate
1.0%
Karthusvs Syndra
Patch26.17
Matches693,760
LaneAll Lanes
TierAll Tiers
Last UpdatedAug 31, 2026 UTC
MethodologyData Methodology
AuthorDakota Chinnick
Karthus vs Syndra is a decisive matchup in LoL patch 26.17. Karthus wins with a 55.6% win rate (+11.1%) over Syndra based on 9 games. Karthus holds the advantage in both the early and late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Syndra matchup.
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Karthus Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Compare against an opponent
Karthus
55.6% WR
VS
Syndra
44.4% WR
Who Wins the Karthus vs Syndra Matchup?
Winner
Karthus
Matches: 9
55.6%
44.4%
7.0
7.1
1,307
923
16,200
14,911
89
89
424
284
0.6
1.1
66.7%
33.3%
50.0%
50.0%
Karthus vs Syndra Matchup Summary
The Karthus vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 9 recent matches analyzed, Karthus wins with a 55.6% win rate compared to Syndra's 44.4%, giving Karthus a 11.1 percentage point advantage. Karthus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Syndra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Syndra leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus players can confidently pick into Syndra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Syndra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Karthus vs Syndra Laning Phase Breakdown
Karthus is favored during the laning phase against Syndra, winning 3 out of 5 key stat categories. Karthus holds advantages in damage, gold income and sustain, making them the stronger laner in this matchup.
Farming
7.0Karthus
7.1Syndra
Karthus and Syndra farm at nearly identical rates in this matchup, with only a 0.0 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.Damage
1,307Karthus
923Syndra
Karthus heavily out-damages Syndra by 384 DMG/min, dominating both short trades and all-in fights. Syndra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.Economy
16,200Karthus
14,911Syndra
Karthus generates a commanding 1,289 more gold per game than Syndra. This substantial economic advantage means Karthus consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Syndra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.Utility
0.6Karthus
1.1Syndra
Syndra provides 0.5 seconds more crowd control per minute than Karthus, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Syndra coordinate with their jungler and control the pace of skirmishes.Sustain
513Karthus
373Syndra
Karthus heals and mitigates 140 more damage per minute than Syndra, providing moderate extra durability. This sustain edge allows Karthus to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Syndra.Best Karthus Build Against Syndra
Boots
Core Items
Spellslinger's Shoes is the optimal boots choice against Syndra, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Syndra are Shadowflame, Zhonya's Hourglass and Void Staff. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Syndra matchup.
Early Game vs Late Game
⚔
Early Game
Karthus
66.7%
+33.3% advantage
Karthus66.7%
Syndra33.3%♕
Late Game
Karthus
50.0%
+0.0% advantage
Karthus50.0%Syndra50.0%Karthus dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Syndra. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Late game (25+ minutes) is equally balanced, with Karthus at 50.0% win rate — only 0.0 points ahead of Syndra. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
Karthus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Syndra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Karthus Runes Against Syndra
Sorcery
Precision
75.0% WR
Running Sorcery primary with Precision secondary allows Karthus to press their advantage against Syndra, amplifying the strengths that make this a favorable matchup.
Karthus matchup data for League of Legends patch 26.17. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 58.14% | 43 | 1.4 | 1,169 | 13,595 | 52.9% | 61.5% | |
| 50.00% | 28 | 1.6 | 1,033 | 13,491 | 50.0% | 50.0% | |
| 40.74% | 27 | 1.5 | 1,169 | 12,531 | 42.1% | 37.5% | |
| 66.67% | 27 | 1.3 | 1,170 | 15,149 | 75.0% | 63.2% | |
| 34.62% | 26 | 1.5 | 1,227 | 14,856 | 11.1% | 47.1% | |
| 50.00% | 26 | 1.6 | 979 | 13,856 | 50.0% | 50.0% | |
| 40.00% | 25 | 1.4 | 1,194 | 14,127 | 46.7% | 30.0% | |
| 47.37% | 19 | 1.5 | 1,375 | 16,409 | 50.0% | 46.7% | |
| 38.89% | 18 | 1.6 | 1,229 | 13,836 | 57.1% | 27.3% | |
| 33.33% | 18 | 6.6 | 1,260 | 13,879 | 37.5% | 30.0% | |
| 38.89% | 18 | 1.4 | 1,114 | 13,845 | 42.9% | 36.4% | |
| 41.18% | 17 | 1.3 | 1,070 | 13,457 | 28.6% | 50.0% | |
| 29.41% | 17 | 1.4 | 1,219 | 13,598 | 14.3% | 40.0% | |
| 70.59% | 17 | 6.7 | 1,255 | 14,128 | 60.0% | 75.0% | |
| 31.25% | 16 | 1.3 | 1,069 | 12,738 | 28.6% | 33.3% | |
| 50.00% | 16 | 2.1 | 1,213 | 14,060 | 50.0% | 50.0% | |
| 73.33% | 15 | 6.7 | 1,085 | 13,251 | 71.4% | 75.0% | |
| 33.33% | 15 | 6.0 | 1,326 | 15,452 | 0.0% | 38.5% | |
| 42.86% | 14 | 1.4 | 1,149 | 12,286 | 42.9% | 42.9% | |
| 61.54% | 13 | 2.0 | 1,030 | 13,491 | 40.0% | 75.0% | |
| 61.54% | 13 | 1.3 | 1,167 | 14,122 | 80.0% | 50.0% | |
| 76.92% | 13 | 6.9 | 1,355 | 14,303 | 66.7% | 85.7% | |
| 58.33% | 12 | 1.8 | 1,404 | 14,600 | 40.0% | 71.4% | |
| 41.67% | 12 | 1.8 | 1,182 | 15,315 | 66.7% | 33.3% | |
| 66.67% | 12 | 1.3 | 1,173 | 12,113 | 66.7% | 66.7% | |
| 25.00% | 12 | 1.7 | 1,027 | 12,217 | 33.3% | 16.7% | |
| 45.45% | 11 | 6.9 | 1,351 | 12,958 | 42.9% | 50.0% | |
| 63.64% | 11 | 1.3 | 1,090 | 12,939 | 50.0% | 71.4% | |
| 45.45% | 11 | 6.5 | 1,257 | 14,605 | 66.7% | 20.0% | |
| 36.36% | 11 | 3.0 | 1,301 | 13,402 | 50.0% | 28.6% | |
| 45.45% | 11 | 1.5 | 1,023 | 12,239 | 25.0% | 57.1% | |
| 60.00% | 10 | 1.9 | 1,183 | 16,849 | 66.7% | 57.1% | |
| 60.00% | 10 | 1.6 | 1,277 | 13,581 | 66.7% | 50.0% | |
| 30.00% | 10 | 1.8 | 923 | 12,157 | 42.9% | 0.0% | |
| 70.00% | 10 | 2.1 | 1,338 | 15,178 | 0.0% | 87.5% | |
| 50.00% | 10 | 6.7 | 1,205 | 13,291 | 40.0% | 60.0% | |
| 66.67% | 9 | 4.2 | 1,164 | 13,695 | 66.7% | 66.7% | |
| 55.56% | 9 | 7.0 | 1,307 | 16,200 | 66.7% | 50.0% | |
| 75.00% | 8 | 1.0 | 1,035 | 12,639 | 80.0% | 66.7% | |
| 50.00% | 8 | 1.2 | 1,399 | 14,092 | 33.3% | 60.0% | |
| 62.50% | 8 | 2.0 | 1,284 | 15,655 | 50.0% | 66.7% | |
| 100.00% | 7 | 6.9 | 1,076 | 11,606 | 100.0% | 100.0% | |
| 57.14% | 7 | 5.3 | 994 | 11,604 | 75.0% | 33.3% | |
| 42.86% | 7 | 4.2 | 1,272 | 14,123 | 50.0% | 40.0% | |
| 71.43% | 7 | 7.3 | 1,318 | 14,541 | 75.0% | 66.7% | |
| 57.14% | 7 | 2.9 | 1,309 | 11,631 | 33.3% | 75.0% | |
| 14.29% | 7 | 1.1 | 905 | 11,097 | 0.0% | 50.0% | |
| 71.43% | 7 | 1.4 | 1,108 | 12,521 | 33.3% | 100.0% | |
| 33.33% | 6 | 4.0 | 1,344 | 14,628 | 50.0% | 25.0% | |
| 83.33% | 6 | 6.9 | 1,244 | 12,336 | 66.7% | 100.0% | |
| 33.33% | 6 | 1.7 | 1,356 | 14,845 | 33.3% | 33.3% | |
| 33.33% | 6 | 6.7 | 1,384 | 15,812 | 50.0% | 0.0% | |
| 83.33% | 6 | 6.7 | 1,561 | 17,210 | 100.0% | 80.0% | |
| 33.33% | 6 | 3.7 | 1,356 | 14,100 | 100.0% | 20.0% | |
| 66.67% | 6 | 0.8 | 1,008 | 10,721 | 75.0% | 50.0% | |
| 80.00% | 5 | 3.8 | 840 | 9,428 | 75.0% | 100.0% | |
| 80.00% | 5 | 2.2 | 1,117 | 12,935 | 66.7% | 100.0% | |
| 20.00% | 5 | 6.8 | 1,217 | 15,013 | 0.0% | 25.0% | |
| 40.00% | 5 | 7.3 | 1,259 | 13,914 | 0.0% | 66.7% | |
| 60.00% | 5 | 7.2 | 1,650 | 16,313 | 100.0% | 33.3% | |
| 40.00% | 5 | 6.0 | 1,261 | 13,239 | 0.0% | 50.0% | |
| 40.00% | 5 | 7.0 | 1,176 | 13,280 | 50.0% | 33.3% | |
| 20.00% | 5 | 3.3 | 1,221 | 13,980 | 0.0% | 25.0% | |
| 40.00% | 5 | 1.8 | 1,112 | 15,486 | 50.0% | 33.3% | |
| 40.00% | 5 | 4.3 | 1,390 | 14,497 | 50.0% | 33.3% | |
| 80.00% | 5 | 1.4 | 989 | 13,329 | 100.0% | 66.7% | |
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Karthus vs Syndra - Frequently Asked Questions
How does Karthus do against Syndra in League of Legends?
Karthus wins the Karthus vs Syndra matchup with a 55.6% win rate compared to Syndra's 44.4%, a 11.1 percentage point difference. This data is based on 9 recent ranked games in patch 26.17.
How does Karthus do against Syndra in the early game?
In the early game, Karthus has the advantage against Syndra with a 66.7% win rate versus 33.3%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Karthus do against Syndra in the late game?
In the late game, Karthus takes over the Karthus vs Syndra matchup with a 50.0% win rate compared to 50.0%. Karthus scales better into team fights and objective contests after 25 minutes.
Who wins the Karthus vs Syndra matchup?
Karthus wins the matchup against Syndra with a 55.6% win rate in League of Legends patch 26.17. The 11.1 percentage point advantage means Karthus is significantly favored in this lane matchup based on 9 games analyzed.
What is the best Karthus build against Syndra?
The best Karthus build against Syndra includes Shadowflame, Zhonya's Hourglass, Void Staff with Spellslinger's Shoes. Check the matchup breakdown above for the full item path and build order.
What are the best Karthus runes against Syndra?
The best Karthus runes against Syndra use the Sorcery primary tree with Precision secondary. This rune setup achieves a 75.0% win rate in the Karthus vs Syndra matchup. See the full rune breakdown in the matchup comparison above.
Does Karthus counter Syndra?
Yes, Karthus has a favorable matchup against Syndra with a 55.6% win rate. Karthus strongly counters Syndra in lane based on current patch 26.17 data.
How do I play Karthus against Syndra?
When playing Karthus against Syndra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
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