Vaynevs Syndra
Vayne vs Syndra is a decisive matchup in LoL patch 26.13. Syndra wins with a 60.0% win rate (+20.0%) over Vayne based on 5 games. Syndra wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Syndra matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Syndra Matchup?
Vayne vs Syndra Matchup Summary
The Vayne vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Syndra wins with a 60.0% win rate compared to Vayne's 40.0%, giving Syndra a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Syndra controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Syndra needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Syndra leads by 0.8s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Syndra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Syndra Laning Phase Breakdown
Syndra is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Syndra holds advantages in farming, gold income and crowd control, making them the stronger laner in this matchup.
Early Game vs Late Game
Vayne33.3%
Syndra66.7%Vayne50.0%Syndra50.0%Syndra dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Vayne. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Late game (25+ minutes) is equally balanced, with Vayne at 50.0% win rate — only 0.0 points ahead of Syndra. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
The power dynamics shift as the game progresses — Syndra has the edge early, but Vayne gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Vayne Runes Against Syndra
Precision
Resolve
The Precision and Resolve rune setup gives Vayne the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Vayne matchup data for League of Legends patch 26.13. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 58.62% | 145 | 5.9 | 771 | 12,511 | 57.8% | 59.5% | |
| 51.75% | 143 | 5.9 | 846 | 13,098 | 52.3% | 51.3% | |
| 43.26% | 141 | 5.5 | 721 | 12,529 | 35.7% | 48.2% | |
| 52.76% | 127 | 6.3 | 823 | 12,163 | 55.0% | 50.8% | |
| 50.00% | 110 | 6.2 | 812 | 12,827 | 47.9% | 51.6% | |
| 53.27% | 107 | 6.0 | 820 | 13,023 | 54.0% | 52.9% | |
| 39.74% | 78 | 6.1 | 795 | 11,992 | 45.2% | 33.3% | |
| 42.25% | 71 | 6.2 | 879 | 13,191 | 37.9% | 45.2% | |
| 54.29% | 70 | 6.2 | 886 | 12,979 | 51.6% | 56.4% | |
| 54.69% | 64 | 6.0 | 847 | 13,371 | 50.0% | 57.9% | |
| 53.57% | 56 | 6.0 | 834 | 12,857 | 53.9% | 53.3% | |
| 50.00% | 54 | 6.0 | 808 | 11,545 | 46.4% | 53.9% | |
| 42.00% | 50 | 6.2 | 753 | 12,285 | 43.5% | 40.7% | |
| 30.43% | 46 | 6.7 | 1,063 | 11,968 | 26.1% | 34.8% | |
| 54.55% | 44 | 5.9 | 756 | 12,694 | 57.1% | 52.2% | |
| 41.03% | 39 | 6.5 | 826 | 11,715 | 40.0% | 42.9% | |
| 44.44% | 36 | 5.8 | 739 | 11,434 | 42.1% | 47.1% | |
| 41.67% | 36 | 6.2 | 995 | 12,622 | 38.9% | 44.4% | |
| 48.57% | 35 | 5.7 | 787 | 12,494 | 53.3% | 45.0% | |
| 66.67% | 33 | 6.3 | 792 | 12,055 | 64.7% | 68.8% | |
| 54.55% | 33 | 6.4 | 795 | 12,299 | 43.8% | 64.7% | |
| 43.75% | 32 | 5.3 | 639 | 10,600 | 35.7% | 50.0% | |
| 56.67% | 30 | 6.8 | 925 | 14,960 | 57.1% | 56.3% | |
| 56.67% | 30 | 5.9 | 907 | 12,705 | 42.9% | 68.8% | |
| 44.83% | 29 | 5.8 | 605 | 10,635 | 41.7% | 47.1% | |
| 46.15% | 26 | 5.9 | 989 | 11,887 | 20.0% | 62.5% | |
| 61.54% | 26 | 5.1 | 1,063 | 11,719 | 62.5% | 61.1% | |
| 42.31% | 26 | 6.0 | 897 | 13,038 | 46.7% | 36.4% | |
| 45.45% | 22 | 5.8 | 992 | 11,792 | 50.0% | 42.9% | |
| 31.82% | 22 | 5.7 | 850 | 9,690 | 33.3% | 30.0% | |
| 63.64% | 22 | 5.9 | 1,048 | 13,703 | 55.6% | 69.2% | |
| 54.55% | 22 | 5.8 | 811 | 13,789 | 66.7% | 46.1% | |
| 65.00% | 20 | 5.8 | 973 | 12,613 | 66.7% | 63.6% | |
| 52.94% | 17 | 6.1 | 826 | 13,930 | 57.1% | 50.0% | |
| 64.71% | 17 | 6.2 | 902 | 14,881 | 57.1% | 70.0% | |
| 64.71% | 17 | 5.9 | 1,481 | 11,218 | 57.1% | 70.0% | |
| 52.94% | 17 | 5.9 | 868 | 11,104 | 62.5% | 44.4% | |
| 56.25% | 16 | 6.0 | 1,010 | 10,777 | 55.6% | 57.1% | |
| 56.25% | 16 | 6.5 | 817 | 10,651 | 55.6% | 57.1% | |
| 46.67% | 15 | 6.2 | 927 | 12,799 | 60.0% | 40.0% | |
| 35.71% | 14 | 6.0 | 706 | 10,579 | 22.2% | 60.0% | |
| 42.86% | 14 | 6.2 | 944 | 12,022 | 60.0% | 33.3% | |
| 50.00% | 14 | 5.7 | 917 | 12,046 | 50.0% | 50.0% | |
| 61.54% | 13 | 6.7 | 930 | 12,377 | 80.0% | 50.0% | |
| 30.77% | 13 | 6.3 | 930 | 11,441 | 37.5% | 20.0% | |
| 23.08% | 13 | 6.1 | 706 | 9,155 | 28.6% | 16.7% | |
| 61.54% | 13 | 5.3 | 1,090 | 12,933 | 66.7% | 57.1% | |
| 38.46% | 13 | 5.4 | 825 | 11,639 | 20.0% | 50.0% | |
| 23.08% | 13 | 5.9 | 862 | 12,777 | 20.0% | 25.0% | |
| 41.67% | 12 | 5.4 | 864 | 12,753 | 50.0% | 37.5% | |
| 45.45% | 11 | 6.5 | 1,113 | 13,236 | 66.7% | 37.5% | |
| 63.64% | 11 | 6.2 | 885 | 10,690 | 40.0% | 83.3% | |
| 63.64% | 11 | 6.6 | 925 | 11,375 | 66.7% | 60.0% | |
| 45.45% | 11 | 6.6 | 868 | 12,739 | 25.0% | 57.1% | |
| 27.27% | 11 | 5.8 | 955 | 14,331 | 33.3% | 25.0% | |
| 54.55% | 11 | 6.1 | 960 | 12,901 | 60.0% | 50.0% | |
| 45.45% | 11 | 5.7 | 950 | 11,174 | 60.0% | 33.3% | |
| 45.45% | 11 | 5.8 | 736 | 11,151 | 16.7% | 80.0% | |
| 36.36% | 11 | 5.2 | 806 | 12,226 | 40.0% | 33.3% | |
| 55.56% | 9 | 6.1 | 1,001 | 10,987 | 50.0% | 66.7% | |
| 66.67% | 9 | 5.6 | 974 | 15,312 | 50.0% | 71.4% | |
| 11.11% | 9 | 6.2 | 916 | 15,190 | 33.3% | 0.0% | |
| 44.44% | 9 | 6.6 | 821 | 13,080 | 40.0% | 50.0% | |
| 33.33% | 9 | 6.2 | 800 | 13,176 | 33.3% | 33.3% | |
| 62.50% | 8 | 6.0 | 975 | 16,558 | 50.0% | 66.7% | |
| 62.50% | 8 | 6.5 | 1,341 | 13,507 | 100.0% | 40.0% | |
| 37.50% | 8 | 6.7 | 933 | 12,083 | 33.3% | 40.0% | |
| 85.71% | 7 | 6.9 | 1,048 | 15,780 | 100.0% | 80.0% | |
| 42.86% | 7 | 6.6 | 805 | 12,364 | 40.0% | 50.0% | |
| 85.71% | 7 | 7.3 | 845 | 15,317 | 0.0% | 85.7% | |
| 71.43% | 7 | 5.2 | 816 | 13,073 | 100.0% | 66.7% | |
| 28.57% | 7 | 5.7 | 711 | 9,332 | 25.0% | 33.3% | |
| 57.14% | 7 | 6.3 | 984 | 14,027 | 50.0% | 60.0% | |
| 16.67% | 6 | 6.4 | 582 | 11,487 | 33.3% | 0.0% | |
| 50.00% | 6 | 5.8 | 766 | 10,859 | 25.0% | 100.0% | |
| 33.33% | 6 | 6.6 | 920 | 13,373 | 0.0% | 40.0% | |
| 83.33% | 6 | 6.3 | 872 | 15,834 | 0.0% | 83.3% | |
| 50.00% | 6 | 7.0 | 1,124 | 12,202 | 75.0% | 0.0% | |
| 16.67% | 6 | 6.3 | 840 | 12,213 | 0.0% | 33.3% | |
| 40.00% | 5 | 5.9 | 362 | 9,930 | 33.3% | 50.0% | |
| 60.00% | 5 | 4.4 | 621 | 11,714 | 33.3% | 100.0% | |
| 80.00% | 5 | 3.7 | 971 | 17,499 | 100.0% | 75.0% | |
| 40.00% | 5 | 6.4 | 741 | 9,713 | 33.3% | 50.0% | |
| 80.00% | 5 | 5.4 | 886 | 13,365 | 100.0% | 50.0% | |
| 60.00% | 5 | 4.7 | 558 | 11,122 | 100.0% | 33.3% | |
| 20.00% | 5 | 6.1 | 1,252 | 15,172 | 0.0% | 25.0% | |
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Vayne vs Syndra - Frequently Asked Questions
How does Vayne do against Syndra in League of Legends?
Syndra wins the Vayne vs Syndra matchup with a 60.0% win rate compared to Vayne's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.13.
How does Vayne do against Syndra in the early game?
In the early game, Syndra has the advantage against Vayne with a 66.7% win rate versus 33.3%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Syndra in the late game?
In the late game, Vayne takes over the Vayne vs Syndra matchup with a 50.0% win rate compared to 50.0%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Syndra matchup?
Syndra wins the matchup against Vayne with a 60.0% win rate in League of Legends patch 26.13. The 20.0 percentage point advantage means Syndra is significantly favored in this lane matchup based on 5 games analyzed.
What is the best Vayne build against Syndra?
The best Vayne build against Syndra includes optimized core items. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Syndra?
The best Vayne runes against Syndra use the Precision primary tree with Resolve secondary. This rune setup achieves a 50.0% win rate in the Vayne vs Syndra matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Syndra?
No, Vayne struggles against Syndra with only a 40.0% win rate. Syndra has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.
How do I play Vayne against Syndra?
When playing Vayne against Syndra, play cautiously and avoid Syndra's power spikes. Focus on safe farming — you outscale Syndra in the late game. Use the matchup-specific build and runes above to optimize your chances.