Vaynevs Syndra
Vayne vs Syndra is a decisive matchup in LoL patch 26.10. Vayne wins with a 55.6% win rate (+11.1%) over Syndra based on 9 games. Vayne wins the early laning phase while Syndra scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Syndra matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Syndra Matchup?
Vayne vs Syndra Matchup Summary
The Vayne vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 9 recent matches analyzed, Vayne wins with a 55.6% win rate compared to Syndra's 44.4%, giving Vayne a 11.1 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Syndra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Syndra reaches their power spikes, while Syndra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Syndra leads by 0.8s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Syndra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Syndra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Syndra Laning Phase Breakdown
Vayne is favored during the laning phase against Syndra, winning 3 out of 5 key stat categories. Vayne holds advantages in damage, gold income and sustain, making them the stronger laner in this matchup.
Best Vayne Build Against Syndra
Immortal Path is the optimal boots choice against Syndra, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Syndra are Hubris, Hexoptics C44 and Fiendhunter Bolts. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Syndra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Syndra matchup.
Early Game vs Late Game
Vayne100.0%
Syndra0.0%Vayne42.9%Syndra57.1%Vayne dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Syndra. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Syndra is far superior in the late game (25+ minutes), boasting a 57.1% win rate — 14.3 points above Vayne. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Vayne must aggressively press their early advantage and close out the game before Syndra reaches their scaling breakpoints. If Syndra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Vayne Runes Against Syndra
Precision
Domination
Running Precision primary with Domination secondary allows Vayne to press their advantage against Syndra, amplifying the strengths that make this a favorable matchup.
Vayne matchup data for League of Legends patch 26.10. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 44.98% | 856 | 6.1 | 880 | 13,322 | 45.6% | 44.5% | |
| 47.13% | 628 | 6.0 | 801 | 13,007 | 45.1% | 48.6% | |
| 46.70% | 621 | 6.0 | 785 | 12,961 | 46.1% | 47.1% | |
| 50.57% | 530 | 6.3 | 849 | 12,932 | 50.4% | 50.7% | |
| 50.76% | 524 | 6.1 | 853 | 13,573 | 46.8% | 53.3% | |
| 47.62% | 483 | 5.7 | 774 | 12,899 | 47.3% | 47.9% | |
| 54.67% | 428 | 6.3 | 888 | 13,110 | 50.0% | 58.9% | |
| 56.75% | 289 | 6.3 | 918 | 13,741 | 54.1% | 59.0% | |
| 52.53% | 217 | 5.9 | 830 | 13,245 | 52.6% | 52.5% | |
| 47.64% | 212 | 6.0 | 797 | 12,592 | 48.5% | 46.8% | |
| 50.25% | 201 | 6.1 | 800 | 12,898 | 45.0% | 54.5% | |
| 59.07% | 193 | 6.4 | 1,016 | 13,025 | 59.1% | 59.1% | |
| 49.21% | 189 | 5.9 | 829 | 12,620 | 48.4% | 50.0% | |
| 57.65% | 170 | 6.2 | 842 | 13,378 | 53.2% | 61.5% | |
| 50.30% | 169 | 5.8 | 808 | 12,793 | 52.6% | 48.4% | |
| 46.01% | 163 | 5.7 | 611 | 11,634 | 40.3% | 49.5% | |
| 50.63% | 158 | 6.0 | 790 | 12,716 | 39.4% | 58.7% | |
| 53.19% | 141 | 6.0 | 903 | 11,554 | 47.4% | 57.1% | |
| 48.23% | 141 | 6.1 | 853 | 13,844 | 56.6% | 43.2% | |
| 48.51% | 134 | 6.2 | 889 | 11,723 | 45.5% | 51.5% | |
| 50.40% | 125 | 6.3 | 813 | 13,600 | 49.1% | 51.4% | |
| 48.36% | 122 | 5.9 | 956 | 12,229 | 52.1% | 46.0% | |
| 47.93% | 121 | 6.5 | 825 | 12,876 | 45.2% | 50.9% | |
| 44.92% | 118 | 6.2 | 940 | 13,191 | 35.9% | 52.3% | |
| 34.21% | 114 | 5.5 | 586 | 10,060 | 31.4% | 36.5% | |
| 58.18% | 110 | 6.0 | 849 | 12,682 | 52.1% | 62.9% | |
| 57.01% | 107 | 6.3 | 873 | 13,730 | 56.8% | 57.1% | |
| 41.12% | 107 | 6.2 | 875 | 13,699 | 35.6% | 45.2% | |
| 52.17% | 92 | 6.4 | 1,150 | 13,161 | 50.0% | 53.5% | |
| 48.86% | 88 | 6.6 | 1,321 | 12,552 | 45.5% | 50.9% | |
| 55.95% | 84 | 6.0 | 985 | 12,419 | 50.0% | 60.4% | |
| 46.99% | 83 | 6.1 | 798 | 11,189 | 28.9% | 62.2% | |
| 48.10% | 79 | 6.3 | 953 | 12,434 | 42.4% | 52.2% | |
| 43.04% | 79 | 6.0 | 952 | 11,620 | 29.7% | 54.8% | |
| 50.67% | 75 | 5.9 | 922 | 12,382 | 56.1% | 44.1% | |
| 51.35% | 74 | 6.3 | 976 | 11,776 | 61.8% | 42.5% | |
| 50.00% | 72 | 6.0 | 1,069 | 11,819 | 57.1% | 43.2% | |
| 53.52% | 71 | 6.6 | 885 | 11,514 | 43.2% | 64.7% | |
| 49.25% | 67 | 6.3 | 907 | 13,964 | 52.0% | 47.6% | |
| 59.38% | 64 | 6.3 | 990 | 13,187 | 59.1% | 59.5% | |
| 60.66% | 61 | 6.3 | 1,004 | 12,193 | 68.0% | 55.6% | |
| 47.46% | 59 | 6.4 | 959 | 11,864 | 44.8% | 50.0% | |
| 57.14% | 56 | 6.1 | 847 | 10,643 | 50.0% | 68.2% | |
| 50.00% | 56 | 5.9 | 874 | 13,786 | 50.0% | 50.0% | |
| 49.09% | 55 | 6.1 | 841 | 13,390 | 50.0% | 48.4% | |
| 44.44% | 54 | 6.1 | 867 | 12,810 | 59.1% | 34.4% | |
| 50.00% | 54 | 6.2 | 740 | 11,465 | 57.1% | 42.3% | |
| 52.94% | 51 | 5.2 | 853 | 11,706 | 40.9% | 62.1% | |
| 48.00% | 50 | 6.2 | 877 | 13,507 | 61.9% | 37.9% | |
| 54.00% | 50 | 6.1 | 811 | 12,061 | 50.0% | 55.9% | |
| 46.94% | 49 | 6.2 | 838 | 12,883 | 40.0% | 51.7% | |
| 52.08% | 48 | 6.1 | 884 | 11,322 | 60.0% | 43.5% | |
| 48.94% | 47 | 5.8 | 899 | 12,001 | 41.2% | 53.3% | |
| 51.11% | 45 | 5.9 | 993 | 12,343 | 75.0% | 37.9% | |
| 47.62% | 42 | 5.8 | 858 | 12,588 | 30.8% | 55.2% | |
| 58.54% | 41 | 6.0 | 844 | 11,580 | 52.4% | 65.0% | |
| 50.00% | 40 | 6.0 | 785 | 12,693 | 47.1% | 52.2% | |
| 42.50% | 40 | 5.9 | 698 | 10,784 | 37.5% | 45.8% | |
| 58.97% | 39 | 5.7 | 798 | 12,670 | 73.3% | 50.0% | |
| 50.00% | 38 | 6.3 | 996 | 12,096 | 50.0% | 50.0% | |
| 47.37% | 38 | 5.9 | 885 | 13,006 | 31.3% | 59.1% | |
| 44.74% | 38 | 6.1 | 736 | 11,743 | 33.3% | 55.0% | |
| 44.44% | 36 | 5.3 | 712 | 11,286 | 42.9% | 46.7% | |
| 58.33% | 36 | 6.6 | 950 | 11,382 | 45.0% | 75.0% | |
| 58.33% | 36 | 6.5 | 959 | 13,118 | 53.9% | 60.9% | |
| 47.22% | 36 | 6.5 | 822 | 13,319 | 50.0% | 45.5% | |
| 44.12% | 34 | 5.4 | 794 | 11,934 | 60.0% | 31.6% | |
| 52.94% | 34 | 5.4 | 1,021 | 13,008 | 37.5% | 66.7% | |
| 56.25% | 32 | 5.2 | 877 | 13,126 | 53.9% | 57.9% | |
| 59.38% | 32 | 6.2 | 767 | 12,764 | 69.2% | 52.6% | |
| 51.61% | 31 | 6.2 | 770 | 11,717 | 40.0% | 62.5% | |
| 45.16% | 31 | 4.7 | 804 | 11,868 | 64.3% | 29.4% | |
| 45.16% | 31 | 6.3 | 975 | 12,909 | 40.0% | 50.0% | |
| 48.28% | 29 | 6.2 | 912 | 11,141 | 50.0% | 46.7% | |
| 34.48% | 29 | 6.3 | 651 | 11,676 | 7.1% | 60.0% | |
| 51.85% | 27 | 6.0 | 764 | 13,315 | 10.0% | 76.5% | |
| 42.31% | 26 | 6.4 | 866 | 12,494 | 36.4% | 46.7% | |
| 64.00% | 25 | 6.5 | 963 | 11,300 | 69.2% | 58.3% | |
| 54.17% | 24 | 6.0 | 835 | 11,089 | 70.0% | 42.9% | |
| 54.17% | 24 | 5.8 | 839 | 12,111 | 45.5% | 61.5% | |
| 39.13% | 23 | 6.1 | 733 | 12,751 | 44.4% | 35.7% | |
| 56.52% | 23 | 6.1 | 956 | 13,245 | 40.0% | 69.2% | |
| 54.55% | 22 | 6.3 | 890 | 10,650 | 36.4% | 72.7% | |
| 52.38% | 21 | 6.0 | 968 | 13,253 | 66.7% | 50.0% | |
| 42.86% | 21 | 5.6 | 842 | 11,903 | 33.3% | 46.7% | |
| 31.58% | 19 | 4.7 | 656 | 12,341 | 30.0% | 33.3% | |
| 57.89% | 19 | 6.2 | 756 | 11,625 | 54.5% | 62.5% | |
| 38.89% | 18 | 6.6 | 922 | 13,233 | 40.0% | 38.5% | |
| 52.94% | 17 | 5.0 | 644 | 10,546 | 50.0% | 60.0% | |
| 41.18% | 17 | 6.1 | 622 | 13,240 | 33.3% | 45.5% | |
| 52.94% | 17 | 6.3 | 1,028 | 13,653 | 71.4% | 40.0% | |
| 52.94% | 17 | 4.6 | 974 | 13,703 | 25.0% | 61.5% | |
| 64.71% | 17 | 6.7 | 914 | 11,709 | 37.5% | 88.9% | |
| 41.18% | 17 | 4.0 | 725 | 11,372 | 57.1% | 30.0% | |
| 50.00% | 16 | 6.1 | 866 | 11,703 | 44.4% | 57.1% | |
| 64.29% | 14 | 6.1 | 759 | 10,988 | 57.1% | 71.4% | |
| 42.86% | 14 | 5.5 | 851 | 12,390 | 50.0% | 37.5% | |
| 46.15% | 13 | 6.5 | 1,007 | 12,797 | 60.0% | 37.5% | |
| 46.15% | 13 | 1.9 | 728 | 13,230 | 33.3% | 57.1% | |
| 50.00% | 12 | 1.8 | 812 | 13,513 | 25.0% | 62.5% | |
| 50.00% | 12 | 5.7 | 874 | 13,263 | 50.0% | 50.0% | |
| 66.67% | 12 | 3.5 | 984 | 13,963 | 62.5% | 75.0% | |
| 45.45% | 11 | 5.5 | 884 | 12,966 | 0.0% | 55.6% | |
| 50.00% | 10 | 3.0 | 749 | 12,603 | 50.0% | 50.0% | |
| 40.00% | 10 | 3.8 | 648 | 12,563 | 33.3% | 50.0% | |
| 60.00% | 10 | 5.1 | 744 | 12,115 | 40.0% | 80.0% | |
| 50.00% | 10 | 6.2 | 828 | 12,426 | 50.0% | 50.0% | |
| 50.00% | 10 | 4.5 | 817 | 11,979 | 80.0% | 20.0% | |
| 55.56% | 9 | 3.3 | 722 | 11,975 | 66.7% | 50.0% | |
| 44.44% | 9 | 3.9 | 1,015 | 8,790 | 40.0% | 50.0% | |
| 55.56% | 9 | 4.9 | 677 | 11,574 | 50.0% | 60.0% | |
| 55.56% | 9 | 6.4 | 872 | 12,030 | 100.0% | 42.9% | |
| 50.00% | 8 | 5.7 | 741 | 10,834 | 50.0% | 50.0% | |
| 62.50% | 8 | 6.4 | 823 | 11,941 | 50.0% | 75.0% | |
| 25.00% | 8 | 4.4 | 818 | 12,091 | 33.3% | 20.0% | |
| 62.50% | 8 | 6.2 | 933 | 12,633 | 50.0% | 75.0% | |
| 42.86% | 7 | 4.2 | 749 | 10,214 | 40.0% | 50.0% | |
| 42.86% | 7 | 3.9 | 471 | 9,224 | 33.3% | 50.0% | |
| 42.86% | 7 | 3.8 | 794 | 13,238 | 0.0% | 60.0% | |
| 57.14% | 7 | 5.1 | 886 | 15,156 | 0.0% | 57.1% | |
| 42.86% | 7 | 5.4 | 647 | 11,864 | 50.0% | 40.0% | |
| 14.29% | 7 | 6.5 | 1,053 | 10,913 | 25.0% | 0.0% | |
| 33.33% | 6 | 3.8 | 765 | 15,452 | 50.0% | 25.0% | |
| 66.67% | 6 | 5.8 | 757 | 14,611 | 100.0% | 33.3% | |
| 16.67% | 6 | 3.2 | 674 | 11,433 | 50.0% | 0.0% | |
| 60.00% | 5 | 5.1 | 888 | 13,120 | 0.0% | 75.0% | |
| 60.00% | 5 | 5.5 | 671 | 10,764 | 0.0% | 75.0% | |
| 80.00% | 5 | 8.3 | 937 | 10,892 | 80.0% | 0.0% | |
| 0.00% | 5 | 5.1 | 693 | 9,654 | 0.0% | 0.0% | |
| 20.00% | 5 | 3.1 | 689 | 12,342 | 0.0% | 25.0% | |
| 60.00% | 5 | 4.4 | 864 | 13,281 | 0.0% | 60.0% | |
| 40.00% | 5 | 6.0 | 891 | 15,554 | 0.0% | 50.0% | |
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Vayne vs Syndra - Frequently Asked Questions
How does Vayne do against Syndra in League of Legends?
Vayne wins the Vayne vs Syndra matchup with a 55.6% win rate compared to Syndra's 44.4%, a 11.1 percentage point difference. This data is based on 9 recent ranked games in patch 26.10.
How does Vayne do against Syndra in the early game?
In the early game, Vayne has the advantage against Syndra with a 100.0% win rate versus 0.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Syndra in the late game?
In the late game, Syndra takes over the Vayne vs Syndra matchup with a 57.1% win rate compared to 42.9%. Syndra scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Syndra matchup?
Vayne wins the matchup against Syndra with a 55.6% win rate in League of Legends patch 26.10. The 11.1 percentage point advantage means Vayne is significantly favored in this lane matchup based on 9 games analyzed.
What is the best Vayne build against Syndra?
The best Vayne build against Syndra includes Hubris, Hexoptics C44, Fiendhunter Bolts with Immortal Path. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Syndra?
The best Vayne runes against Syndra use the Precision primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Syndra matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Syndra?
Yes, Vayne has a favorable matchup against Syndra with a 55.6% win rate. Vayne strongly counters Syndra in lane based on current patch 26.10 data.
How do I play Vayne against Syndra?
When playing Vayne against Syndra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.