Vaynevs Syndra
Vayne vs Syndra is a decisive matchup in LoL patch 26.3. Syndra wins with a 66.7% win rate (+33.3%) over Vayne based on 12 games. Syndra holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Syndra matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Syndra(33.3%)Who Wins the Vayne vs Syndra Matchup?
Vayne vs Syndra Matchup Summary
The Vayne vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 12 recent matches analyzed, Syndra wins with a 66.7% win rate compared to Vayne's 33.3%, giving Syndra a 33.3 percentage point advantage. Syndra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Syndra leads by 1.2s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Syndra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Syndra Laning Phase Breakdown
Syndra is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Vayne Build Against Syndra
Chainlaced Crushers is the optimal boots choice against Syndra, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Syndra are Kraken Slayer, Blade of The Ruined King and Spirit Visage. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Syndra matchup.
Early Game vs Late Game
Vayne28.6%Syndra71.4%Vayne40.0%Syndra60.0%Syndra dominates the early game (first 15 minutes) with a commanding 71.4% win rate — a 42.9 percentage point lead over Vayne. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Syndra is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Vayne. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.
Syndra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Vayne Runes Against Syndra
Precision
Resolve
The Precision and Resolve rune setup gives Vayne the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Vayne matchup data for League of Legends patch 26.3. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 49.65% | 576 | 5.9 | 841 | 13,504 | 45.4% | 52.9% | |
| 50.29% | 511 | 6.1 | 823 | 12,979 | 51.4% | 49.2% | |
| 46.59% | 455 | 5.8 | 805 | 13,180 | 46.9% | 46.4% | |
| 48.01% | 377 | 6.2 | 869 | 13,993 | 47.3% | 48.6% | |
| 52.58% | 329 | 6.4 | 893 | 13,536 | 52.8% | 52.4% | |
| 53.63% | 289 | 6.0 | 833 | 13,299 | 54.7% | 52.6% | |
| 52.19% | 274 | 6.2 | 902 | 13,242 | 49.6% | 54.6% | |
| 48.02% | 252 | 6.3 | 960 | 14,803 | 53.7% | 43.8% | |
| 59.04% | 188 | 6.5 | 899 | 13,719 | 63.4% | 54.0% | |
| 52.69% | 186 | 6.1 | 889 | 13,674 | 52.4% | 52.9% | |
| 51.14% | 176 | 6.2 | 849 | 13,311 | 56.7% | 45.4% | |
| 47.37% | 152 | 5.9 | 904 | 13,269 | 48.0% | 46.8% | |
| 54.01% | 137 | 5.9 | 810 | 12,363 | 48.6% | 60.3% | |
| 57.89% | 133 | 6.3 | 902 | 14,123 | 54.1% | 61.1% | |
| 46.56% | 131 | 6.0 | 864 | 13,839 | 37.3% | 54.2% | |
| 56.59% | 129 | 6.4 | 907 | 13,685 | 50.0% | 62.3% | |
| 53.33% | 105 | 6.0 | 861 | 13,606 | 53.2% | 53.5% | |
| 57.84% | 102 | 6.4 | 918 | 12,422 | 62.5% | 53.7% | |
| 55.70% | 79 | 6.1 | 893 | 13,046 | 46.1% | 65.0% | |
| 53.33% | 75 | 6.2 | 862 | 13,103 | 46.1% | 61.1% | |
| 43.24% | 74 | 5.8 | 871 | 12,761 | 38.2% | 47.5% | |
| 60.87% | 69 | 6.0 | 850 | 11,266 | 54.5% | 66.7% | |
| 40.30% | 67 | 6.4 | 848 | 12,412 | 38.5% | 42.9% | |
| 47.76% | 67 | 6.1 | 920 | 13,001 | 51.5% | 44.1% | |
| 46.03% | 63 | 6.4 | 980 | 12,234 | 55.2% | 38.2% | |
| 62.30% | 61 | 6.3 | 933 | 13,605 | 65.6% | 58.6% | |
| 34.48% | 58 | 5.5 | 651 | 11,519 | 31.6% | 35.9% | |
| 56.90% | 58 | 6.4 | 977 | 14,739 | 60.0% | 54.5% | |
| 39.29% | 56 | 5.9 | 751 | 11,287 | 25.0% | 58.3% | |
| 56.36% | 55 | 6.3 | 887 | 14,113 | 54.2% | 58.1% | |
| 36.36% | 55 | 5.5 | 623 | 11,299 | 33.3% | 38.7% | |
| 54.55% | 55 | 6.2 | 1,098 | 12,767 | 55.6% | 53.6% | |
| 50.00% | 54 | 6.2 | 908 | 12,771 | 57.7% | 42.9% | |
| 46.94% | 49 | 5.9 | 765 | 11,452 | 56.0% | 37.5% | |
| 41.30% | 46 | 6.1 | 1,093 | 13,551 | 30.8% | 45.5% | |
| 46.67% | 45 | 6.2 | 1,254 | 11,294 | 54.5% | 39.1% | |
| 45.24% | 42 | 6.4 | 958 | 11,877 | 45.0% | 45.5% | |
| 51.22% | 41 | 6.2 | 938 | 10,299 | 41.7% | 64.7% | |
| 52.50% | 40 | 5.9 | 1,049 | 12,665 | 41.2% | 60.9% | |
| 48.65% | 37 | 5.8 | 873 | 13,390 | 58.8% | 40.0% | |
| 44.44% | 36 | 6.0 | 833 | 12,647 | 35.3% | 52.6% | |
| 28.57% | 35 | 5.7 | 757 | 11,334 | 12.5% | 42.1% | |
| 51.43% | 35 | 6.0 | 926 | 13,522 | 66.7% | 40.0% | |
| 54.29% | 35 | 6.4 | 938 | 13,370 | 66.7% | 47.8% | |
| 59.38% | 32 | 6.2 | 987 | 13,291 | 81.8% | 47.6% | |
| 43.75% | 32 | 6.7 | 1,212 | 14,052 | 50.0% | 40.9% | |
| 62.07% | 29 | 6.2 | 974 | 14,023 | 72.7% | 55.6% | |
| 57.14% | 28 | 6.2 | 883 | 13,510 | 66.7% | 50.0% | |
| 60.71% | 28 | 6.1 | 914 | 12,722 | 55.6% | 63.2% | |
| 60.71% | 28 | 5.9 | 1,047 | 13,268 | 55.6% | 63.2% | |
| 48.15% | 27 | 6.9 | 1,006 | 13,443 | 66.7% | 33.3% | |
| 53.85% | 26 | 6.3 | 1,047 | 14,196 | 55.6% | 52.9% | |
| 61.54% | 26 | 6.2 | 918 | 12,757 | 64.3% | 58.3% | |
| 52.00% | 25 | 5.8 | 717 | 11,149 | 53.3% | 50.0% | |
| 40.00% | 25 | 6.0 | 828 | 12,282 | 53.9% | 25.0% | |
| 50.00% | 24 | 6.0 | 925 | 14,326 | 37.5% | 56.3% | |
| 43.48% | 23 | 6.1 | 851 | 12,671 | 50.0% | 40.0% | |
| 59.09% | 22 | 5.8 | 868 | 12,292 | 44.4% | 69.2% | |
| 59.09% | 22 | 6.2 | 816 | 11,368 | 53.9% | 66.7% | |
| 47.62% | 21 | 6.6 | 880 | 12,950 | 30.0% | 63.6% | |
| 55.00% | 20 | 5.9 | 861 | 10,505 | 50.0% | 66.7% | |
| 45.00% | 20 | 5.8 | 998 | 12,849 | 71.4% | 30.8% | |
| 52.63% | 19 | 5.6 | 929 | 12,029 | 50.0% | 53.9% | |
| 68.42% | 19 | 6.4 | 933 | 14,176 | 66.7% | 69.2% | |
| 38.89% | 18 | 6.2 | 798 | 12,687 | 40.0% | 37.5% | |
| 50.00% | 18 | 6.6 | 734 | 12,199 | 25.0% | 70.0% | |
| 35.29% | 17 | 5.9 | 845 | 13,845 | 11.1% | 62.5% | |
| 68.75% | 16 | 6.5 | 707 | 12,648 | 62.5% | 75.0% | |
| 46.67% | 15 | 5.8 | 818 | 14,106 | 0.0% | 70.0% | |
| 46.67% | 15 | 6.6 | 993 | 14,106 | 62.5% | 28.6% | |
| 46.67% | 15 | 5.0 | 793 | 10,587 | 62.5% | 28.6% | |
| 14.29% | 14 | 5.9 | 708 | 10,537 | 0.0% | 33.3% | |
| 35.71% | 14 | 3.6 | 939 | 14,091 | 40.0% | 33.3% | |
| 64.29% | 14 | 6.5 | 869 | 12,435 | 60.0% | 75.0% | |
| 76.92% | 13 | 6.7 | 1,027 | 14,510 | 100.0% | 70.0% | |
| 53.85% | 13 | 6.3 | 894 | 12,364 | 60.0% | 50.0% | |
| 53.85% | 13 | 6.2 | 887 | 11,915 | 42.9% | 66.7% | |
| 33.33% | 12 | 6.0 | 737 | 11,334 | 28.6% | 40.0% | |
| 81.82% | 11 | 5.8 | 869 | 13,919 | 75.0% | 85.7% | |
| 54.55% | 11 | 5.9 | 894 | 14,635 | 50.0% | 57.1% | |
| 27.27% | 11 | 5.5 | 790 | 10,962 | 33.3% | 20.0% | |
| 36.36% | 11 | 5.8 | 749 | 13,940 | 33.3% | 37.5% | |
| 72.73% | 11 | 5.9 | 1,151 | 12,727 | 60.0% | 83.3% | |
| 80.00% | 10 | 6.7 | 909 | 13,111 | 50.0% | 100.0% | |
| 50.00% | 10 | 5.5 | 1,000 | 15,124 | 0.0% | 55.6% | |
| 11.11% | 9 | 3.0 | 829 | 9,335 | 25.0% | 0.0% | |
| 55.56% | 9 | 5.0 | 875 | 13,338 | 40.0% | 75.0% | |
| 44.44% | 9 | 6.1 | 1,000 | 12,344 | 40.0% | 50.0% | |
| 55.56% | 9 | 5.6 | 525 | 10,348 | 66.7% | 33.3% | |
| 75.00% | 8 | 4.9 | 664 | 9,711 | 80.0% | 66.7% | |
| 50.00% | 8 | 5.5 | 762 | 11,494 | 33.3% | 60.0% | |
| 12.50% | 8 | 6.1 | 821 | 11,113 | 0.0% | 20.0% | |
| 0.00% | 8 | 5.7 | 618 | 7,812 | 0.0% | 0.0% | |
| 14.29% | 7 | 5.9 | 881 | 10,623 | 0.0% | 33.3% | |
| 85.71% | 7 | 5.6 | 881 | 14,579 | 100.0% | 80.0% | |
| 83.33% | 6 | 2.2 | 679 | 9,786 | 83.3% | 0.0% | |
| 33.33% | 6 | 4.9 | 834 | 12,727 | 25.0% | 50.0% | |
| 83.33% | 6 | 4.4 | 756 | 12,109 | 100.0% | 50.0% | |
| 66.67% | 6 | 6.3 | 864 | 11,729 | 33.3% | 100.0% | |
| 60.00% | 5 | 6.7 | 1,134 | 17,090 | 100.0% | 50.0% | |
| 20.00% | 5 | 6.1 | 860 | 12,884 | 0.0% | 33.3% | |
| 20.00% | 5 | 1.0 | 605 | 9,895 | 0.0% | 50.0% | |
| 20.00% | 5 | 6.0 | 986 | 13,530 | 0.0% | 50.0% | |
| 0.00% | 5 | 3.8 | 919 | 13,380 | 0.0% | 0.0% | |
| 40.00% | 5 | 4.2 | 627 | 9,293 | 25.0% | 100.0% | |
| 60.00% | 5 | 6.6 | 1,202 | 14,968 | 33.3% | 100.0% | |
| 80.00% | 5 | 7.5 | 1,172 | 15,045 | 66.7% | 100.0% | |
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Vayne vs Syndra - Frequently Asked Questions
How does Vayne do against Syndra in League of Legends?
Syndra wins the Vayne vs Syndra matchup with a 66.7% win rate compared to Vayne's 33.3%, a 33.3 percentage point difference. This data is based on 12 recent ranked games in patch 26.3.
How does Vayne do against Syndra in the early game?
In the early game, Syndra has the advantage against Vayne with a 71.4% win rate versus 28.6%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Syndra in the late game?
In the late game, Syndra takes over the Vayne vs Syndra matchup with a 60.0% win rate compared to 40.0%. Syndra scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Syndra matchup?
Syndra wins the matchup against Vayne with a 66.7% win rate in League of Legends patch 26.3. The 33.3 percentage point advantage means Syndra is significantly favored in this lane matchup based on 12 games analyzed.
What is the best Vayne build against Syndra?
The best Vayne build against Syndra includes Kraken Slayer, Blade of The Ruined King, Spirit Visage with Chainlaced Crushers. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Syndra?
The best Vayne runes against Syndra use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Syndra matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Syndra?
No, Vayne struggles against Syndra with only a 33.3% win rate. Syndra has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.
How do I play Vayne against Syndra?
When playing Vayne against Syndra, play cautiously and avoid Syndra's power spikes. Look for jungle assistance and team-dependent plays since Syndra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.