Lissandra - League of Legends Champion
Win Rate
51.3%
Pick Rate
2.2%

Lissandravs Vex

AMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 19, 2026
MethodologyData Methodology

Lissandra vs Vex is a decisive matchup in LoL patch 26.7. Lissandra wins with a 53.6% win rate (+7.1%) over Vex based on 28 games. Lissandra wins the early laning phase while Vex scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Vex matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vex - 53.6% win rateVex(53.6%)
Lissandra - 53.6% win rate in this matchup
Lissandra
53.6% WR
VS
Vex vs Lissandra matchup - 46.4% win rate
Vex
46.4% WR

Who Wins the Lissandra vs Vex Matchup?

Lissandra wins the Lissandra vs Vex matchup
Winner
Lissandra
Matches: 28
53.6%
Win Rate
46.4%
6.9
CS / min
6.1
834
DMG / min
922
10,912
Gold / game
10,285
160
Heal / min
86
396
DMG Mitigated / min
477
1.6
CC / min
1.1
62.5%
Early Game WR
37.5%
41.7%
Late Game WR
58.3%

Lissandra vs Vex Matchup Summary

The Lissandra vs Vex matchup is a decisive matchup in League of Legends ranked play. Based on 28 recent matches analyzed, Lissandra wins with a 53.6% win rate compared to Vex's 46.4%, giving Lissandra a 7.1 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Vex outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Vex reaches their power spikes, while Vex should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Vex and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vex away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Vex Laning Phase Breakdown

Lissandra wins the laning phase against Vex in League of Legends

Lissandra is favored during the laning phase against Vex, winning 3 out of 5 key stat categories. Lissandra holds advantages in farming, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.9Lissandra
6.1Vex
Lissandra edges out Vex by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
834Lissandra
922Vex
Vex heavily out-damages Lissandra by 87 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vex's sustained damage advantage take over.
Economy
10,912Lissandra
10,285Vex
Lissandra earns 627 more gold per game than Vex, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Lissandra slightly faster item completions.
Utility
1.6Lissandra
1.1Vex
Lissandra provides 0.5 seconds more crowd control per minute than Vex, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
557Lissandra
563Vex
Lissandra and Vex have comparable sustain profiles, with only 7 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Lissandra Build Against Vex

Spellslinger's Shoes is the optimal boots choice against Vex, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Vex are Shadowflame, Zhonya's Hourglass and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 4 games, proving it to be a reliable item path when facing Vex. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Vex matchup.

Early Game vs Late Game

Early Game
Lissandra
62.5%
+25.0% advantage
Lissandra early game win rateLissandra62.5%
Vex early game win rateVex37.5%
Late Game
Vex
58.3%
+16.7% advantage
Lissandra late game win rateLissandra41.7%
Vex late game win rateVex58.3%

Lissandra dominates the early game (first 15 minutes) with a commanding 62.5% win rate — a 25.0 percentage point lead over Vex. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vex is far superior in the late game (25+ minutes), boasting a 58.3% win rate — 16.7 points above Lissandra. Extended games heavily favor Vex, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Lissandra must aggressively press their early advantage and close out the game before Vex reaches their scaling breakpoints. If Vex survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Lissandra Runes Against Vex

Sorcery rune tree - Lissandra primary runes vs VexSorcery
Arcane Comet - best Lissandra rune vs VexManaflow Band - best Lissandra rune vs VexTranscendence - best Lissandra rune vs VexScorch - best Lissandra rune vs Vex
Domination rune tree - Lissandra secondary runes vs VexDomination
Cheap Shot - best Lissandra rune vs VexUltimate Hunter - best Lissandra rune vs Vex
71.4% WR

Running Sorcery primary with Domination secondary allows Lissandra to press their advantage against Vex, amplifying the strengths that make this a favorable matchup.


Lissandra matchup data for League of Legends patch 26.7. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
60.00%1306.883712,37853.6%64.9%
57.52%1136.882011,83565.2%52.2%
50.00%766.890711,85747.2%52.5%
45.95%746.778211,93537.5%52.4%
47.95%736.982512,39648.3%47.7%
52.11%717.081212,61135.7%62.8%
53.62%696.788911,32658.1%50.0%
54.55%666.798912,99555.2%54.0%
50.00%626.990112,04736.7%62.5%
54.10%616.687711,06545.5%64.3%
57.38%616.276711,40053.6%60.6%
34.48%586.766810,83031.4%39.1%
40.00%556.372811,33333.3%45.2%
46.94%496.975711,65340.0%51.7%
50.00%486.776511,97850.0%50.0%
50.00%406.476411,31941.2%56.5%
65.00%407.283311,56863.6%66.7%
56.41%397.084511,79244.4%66.7%
60.00%356.876110,99150.0%70.6%
48.57%356.881511,55440.0%55.0%
36.36%336.784111,39846.7%27.8%
21.21%336.478711,43923.1%20.0%
63.33%307.380811,58476.5%46.1%
62.07%297.188313,06883.3%47.1%
58.62%296.596211,72763.6%55.6%
53.57%286.983410,91262.5%41.7%
46.43%286.68679,78147.1%45.5%
53.57%286.881411,53950.0%56.3%
59.26%277.079712,15157.1%61.5%
69.23%266.586913,22971.4%68.4%
57.69%266.679612,06775.0%42.9%
40.00%257.276711,82854.5%28.6%
64.00%256.680511,12450.0%73.3%
41.67%246.992712,63340.0%42.9%
66.67%247.178811,24454.5%76.9%
73.68%197.196712,77550.0%90.9%
44.44%187.31,06512,47460.0%25.0%
64.71%177.290311,48980.0%42.9%
33.33%156.473710,70622.2%50.0%
57.14%146.289412,26342.9%71.4%
42.86%147.375110,43150.0%25.0%
76.92%136.783113,11175.0%77.8%
38.46%136.082212,47860.0%25.0%
30.77%136.896711,40720.0%37.5%
15.38%136.584811,09216.7%14.3%
45.45%116.480812,11440.0%50.0%
27.27%116.792811,21620.0%33.3%
54.55%116.888611,95450.0%57.1%
40.00%106.882512,83166.7%28.6%
50.00%106.452910,44128.6%100.0%
55.56%96.295114,28150.0%57.1%
88.89%97.280612,70675.0%100.0%
55.56%97.288211,46775.0%40.0%
55.56%95.672312,03950.0%60.0%
55.56%97.786112,78766.7%50.0%
75.00%87.487510,71080.0%66.7%
57.14%77.387510,78575.0%33.3%
42.86%75.873510,32566.7%25.0%
85.71%77.087111,26283.3%100.0%
71.43%76.173511,33280.0%50.0%
50.00%61.761410,6240.0%60.0%
83.33%67.91,14313,99850.0%100.0%
33.33%67.796512,2420.0%66.7%
33.33%66.686711,32825.0%50.0%
50.00%62.45439,94466.7%33.3%
83.33%67.183312,020100.0%80.0%
16.67%67.26078,27816.7%0.0%
60.00%56.01,16411,19766.7%50.0%
40.00%53.07276,78640.0%0.0%
20.00%57.793410,62525.0%0.0%
20.00%55.05978,21425.0%0.0%
40.00%53.45178,76125.0%100.0%
80.00%55.064712,91850.0%100.0%
40.00%56.783411,7270.0%66.7%
60.00%56.077611,837100.0%33.3%
40.00%56.374111,1560.0%50.0%
60.00%56.897912,10050.0%66.7%
80.00%56.51,08510,600100.0%66.7%

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Lissandra vs Vex - Frequently Asked Questions

How does Lissandra do against Vex in League of Legends?

Lissandra wins the Lissandra vs Vex matchup with a 53.6% win rate compared to Vex's 46.4%, a 7.1 percentage point difference. This data is based on 28 recent ranked games in patch 26.7.

How does Lissandra do against Vex in the early game?

In the early game, Lissandra has the advantage against Vex with a 62.5% win rate versus 37.5%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Vex in the late game?

In the late game, Vex takes over the Lissandra vs Vex matchup with a 58.3% win rate compared to 41.7%. Vex scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Vex matchup?

Lissandra wins the matchup against Vex with a 53.6% win rate in League of Legends patch 26.7. The 7.1 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 28 games analyzed.

What is the best Lissandra build against Vex?

The best Lissandra build against Vex includes Shadowflame, Zhonya's Hourglass, Malignance with Spellslinger's Shoes. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Vex?

The best Lissandra runes against Vex use the Sorcery primary tree with Domination secondary. This rune setup achieves a 71.4% win rate in the Lissandra vs Vex matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Vex?

Yes, Lissandra has a favorable matchup against Vex with a 53.6% win rate. Lissandra strongly counters Vex in lane based on current patch 26.7 data.

How do I play Lissandra against Vex?

When playing Lissandra against Vex, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.