Lissandra - League of Legends Champion
Win Rate
50.2%
Pick Rate
1.2%

Lissandravs Vex

BMage
Patch26.4
Matches1,089,240
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 5, 2026
MethodologyData Methodology

Lissandra vs Vex is a decisive matchup in LoL patch 26.4. Lissandra wins with a 56.5% win rate (+13.0%) over Vex based on 23 games. Vex wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Vex matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vex - 56.5% win rateVex(56.5%)
Lissandra - 56.5% win rate in this matchup
Lissandra
56.5% WR
VS
Vex vs Lissandra matchup - 43.5% win rate
Vex
43.5% WR

Who Wins the Lissandra vs Vex Matchup?

Lissandra wins the Lissandra vs Vex matchup
Winner
Lissandra
Matches: 23
56.5%
Win Rate
43.5%
6.7
CS / min
6.5
812
DMG / min
925
12,034
Gold / game
12,010
155
Heal / min
89
422
DMG Mitigated / min
460
1.7
CC / min
1.0
45.5%
Early Game WR
54.5%
66.7%
Late Game WR
33.3%

Lissandra vs Vex Matchup Summary

The Lissandra vs Vex matchup is a decisive matchup in League of Legends ranked play. Based on 23 recent matches analyzed, Lissandra wins with a 56.5% win rate compared to Vex's 43.5%, giving Lissandra a 13.0 percentage point advantage. Game phase dynamics play a critical role here: Vex controls the early laning stage, but Lissandra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vex needs to press advantages before Lissandra reaches their power spikes, while Lissandra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 0.6s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Vex and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vex away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Vex Laning Phase Breakdown

Lissandra wins the laning phase against Vex in League of Legends

Lissandra is favored during the laning phase against Vex, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.7Lissandra
6.5Vex
Lissandra and Vex farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
812Lissandra
925Vex
Vex heavily out-damages Lissandra by 113 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vex's sustained damage advantage take over.
Economy
12,034Lissandra
12,010Vex
Lissandra and Vex generate nearly equal gold per game, with just a 24 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.7Lissandra
1.0Vex
Lissandra provides 0.6 seconds more crowd control per minute than Vex, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
577Lissandra
549Vex
Lissandra and Vex have comparable sustain profiles, with only 29 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Lissandra Build Against Vex

Spellslinger's Shoes is the optimal boots choice against Vex, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Vex are Shadowflame, Zhonya's Hourglass and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Vex. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Vex matchup.

Early Game vs Late Game

Early Game
Vex
54.5%
+9.1% advantage
Lissandra early game win rateLissandra45.5%
Vex early game win rateVex54.5%
Late Game
Lissandra
66.7%
+33.3% advantage
Lissandra late game win rateLissandra66.7%
Vex late game win rateVex33.3%

Vex dominates the early game (first 15 minutes) with a commanding 54.5% win rate — a 9.1 percentage point lead over Lissandra. This lopsided early game means Vex can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lissandra is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Vex. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Vex must aggressively press their early advantage and close out the game before Lissandra reaches their scaling breakpoints. If Lissandra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Lissandra Runes Against Vex

Sorcery rune tree - Lissandra primary runes vs VexSorcery
Arcane Comet - best Lissandra rune vs VexManaflow Band - best Lissandra rune vs VexTranscendence - best Lissandra rune vs VexScorch - best Lissandra rune vs Vex
Domination rune tree - Lissandra secondary runes vs VexDomination
Cheap Shot - best Lissandra rune vs VexUltimate Hunter - best Lissandra rune vs Vex
100.0% WR

Running Sorcery primary with Domination secondary allows Lissandra to press their advantage against Vex, amplifying the strengths that make this a favorable matchup.


Lissandra matchup data for League of Legends patch 26.4. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
55.98%2096.880911,76352.8%58.5%
55.97%1596.976911,56858.4%53.7%
49.00%1006.580311,85953.9%45.9%
48.39%946.882212,21051.2%46.0%
48.39%946.972011,47948.9%47.8%
45.74%946.879811,48653.2%38.3%
53.41%886.687511,82251.2%55.3%
55.70%796.675011,46151.4%59.1%
54.41%686.894611,94160.0%50.0%
41.27%636.968511,31242.4%40.0%
41.07%566.162910,34744.0%38.7%
48.00%516.679611,84644.0%52.0%
54.00%506.277011,93345.0%60.0%
46.94%496.376711,71652.6%43.3%
48.94%476.485811,29056.5%41.7%
60.00%456.775411,92857.1%61.3%
45.45%446.591812,40447.4%44.0%
53.66%426.670711,50452.6%54.5%
42.86%426.687312,16358.8%32.0%
62.50%416.177311,62470.6%56.5%
52.50%406.777210,82952.4%52.6%
51.28%396.987212,55163.2%40.0%
57.89%386.673510,88760.9%53.3%
48.57%366.770011,10344.4%52.9%
42.86%357.278511,92837.5%47.4%
66.67%336.679812,32658.3%71.4%
28.13%326.975910,82026.7%29.4%
64.52%316.769311,03860.0%68.8%
46.43%286.978010,70343.8%50.0%
42.86%285.280112,55736.4%47.1%
44.44%276.477411,45327.3%56.3%
44.00%256.270511,17153.9%33.3%
33.33%247.090412,24336.4%30.8%
56.52%236.781212,03445.5%66.7%
43.48%236.786713,30371.4%31.3%
47.62%226.577612,69050.0%46.7%
45.00%206.884811,33955.6%36.4%
42.11%195.875411,75366.7%30.8%
72.22%186.886312,48866.7%77.8%
47.06%187.090112,39060.0%41.7%
41.18%175.268011,24722.2%62.5%
70.59%175.883312,03683.3%63.6%
56.25%165.582811,22083.3%40.0%
50.00%167.47649,95162.5%37.5%
53.33%157.466410,56670.0%20.0%
45.45%111.95159,14833.3%50.0%
90.00%104.560210,870100.0%80.0%
30.00%101.952210,30433.3%28.6%
50.00%106.689710,50966.7%25.0%
50.00%107.876113,21133.3%75.0%
50.00%106.886610,98650.0%50.0%
50.00%104.05509,29166.7%25.0%
66.67%94.578211,55766.7%66.7%
66.67%93.981410,70175.0%60.0%
55.56%92.05308,78166.7%50.0%
22.22%96.873912,20633.3%16.7%
55.56%97.988112,08250.0%60.0%
44.44%97.58528,37457.1%0.0%
62.50%96.567310,30360.0%66.7%
12.50%86.264910,22825.0%0.0%
42.86%87.072111,1980.0%60.0%
62.50%87.074911,40875.0%50.0%
37.50%87.177210,74825.0%50.0%
28.57%77.61,10412,72750.0%0.0%
71.43%71.65829,690100.0%50.0%
42.86%75.785512,225100.0%33.3%
42.86%76.41,03315,01250.0%40.0%
28.57%77.564810,02740.0%0.0%
42.86%75.465312,28775.0%0.0%
57.14%72.85509,01433.3%75.0%
28.57%71.749710,6060.0%33.3%
42.86%71.956810,742100.0%20.0%
57.14%76.092414,1350.0%80.0%
42.86%71.96829,43133.3%50.0%
71.43%76.469011,06550.0%100.0%
57.14%76.889613,144100.0%50.0%
33.33%62.36078,40033.3%33.3%
50.00%66.583113,669100.0%40.0%
50.00%66.574010,74466.7%33.3%
33.33%61.64478,57050.0%0.0%
33.33%67.771111,40566.7%0.0%
16.67%65.756010,4190.0%25.0%
16.67%62.158610,8120.0%33.3%
25.00%51.963111,3670.0%25.0%
40.00%57.27389,34850.0%33.3%
0.00%56.597412,6900.0%0.0%
0.00%56.290811,5770.0%0.0%
40.00%55.25569,54566.7%0.0%
80.00%56.384010,265100.0%50.0%
40.00%55.969811,472100.0%0.0%
40.00%53.06539,19333.3%50.0%
60.00%51.637710,9390.0%60.0%
80.00%55.788511,943100.0%66.7%
100.00%56.785512,734100.0%100.0%
20.00%56.391413,6630.0%25.0%
80.00%56.699313,305100.0%66.7%
20.00%56.579612,1950.0%25.0%
60.00%58.01,0728,89450.0%100.0%
80.00%57.090014,195100.0%66.7%
60.00%56.765213,7960.0%75.0%
40.00%56.887212,56250.0%33.3%
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Lissandra vs Vex - Frequently Asked Questions

How does Lissandra do against Vex in League of Legends?

Lissandra wins the Lissandra vs Vex matchup with a 56.5% win rate compared to Vex's 43.5%, a 13.0 percentage point difference. This data is based on 23 recent ranked games in patch 26.4.

How does Lissandra do against Vex in the early game?

In the early game, Vex has the advantage against Lissandra with a 54.5% win rate versus 45.5%. Vex players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Vex in the late game?

In the late game, Lissandra takes over the Lissandra vs Vex matchup with a 66.7% win rate compared to 33.3%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Vex matchup?

Lissandra wins the matchup against Vex with a 56.5% win rate in League of Legends patch 26.4. The 13.0 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 23 games analyzed.

What is the best Lissandra build against Vex?

The best Lissandra build against Vex includes Shadowflame, Zhonya's Hourglass, Malignance with Spellslinger's Shoes. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Vex?

The best Lissandra runes against Vex use the Sorcery primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Vex matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Vex?

Yes, Lissandra has a favorable matchup against Vex with a 56.5% win rate. Lissandra strongly counters Vex in lane based on current patch 26.4 data.

How do I play Lissandra against Vex?

When playing Lissandra against Vex, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Vex. Build the recommended items and runes for this specific matchup for the best results.