
Warwickvs Vayne
Warwick vs Vayne is a decisive matchup in LoL patch 26.9. Vayne wins with a 75.0% win rate (+50.0%) over Warwick based on 8 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Warwick build, runes, laning stats, and strategies for the Warwick vs Vayne matchup.
Warwick Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Warwick performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Warwick vs Vayne Matchup?

Warwick vs Vayne Matchup Summary
The Warwick vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 8 recent matches analyzed, Vayne wins with a 75.0% win rate compared to Warwick's 25.0%, giving Vayne a 50.0 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Warwick players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Warwick leads by 1,026 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Warwick players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Warwick vs Vayne Laning Phase Breakdown
Warwick is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Warwick holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.
Best Warwick Build Against Vayne
Mercury's Treads is the optimal boots choice against Vayne, providing the mobility and stats Warwick needs most in this matchup. The top-performing core items for Warwick against Vayne are Titanic Hydra, Blade of The Ruined King and Thornmail. This combination gives Warwick an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Warwick vs Vayne matchup.
Early Game vs Late Game
Vayne dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Warwick. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Vayne is far superior in the late game (25+ minutes), boasting a 80.0% win rate — 60.0 points above Warwick. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Warwick players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Warwick Runes Against Vayne
The Precision and Sorcery rune setup gives Warwick the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Warwick matchup data for League of Legends patch 26.9. The table below shows Warwick's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Warwick build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 47.62% | 63 | 1.0 | 689 | 12,701 | 54.8% | 40.6% | |
| 50.00% | 52 | 1.2 | 641 | 12,623 | 47.1% | 51.4% | |
| 54.17% | 48 | 1.0 | 709 | 12,207 | 45.0% | 60.7% | |
| 44.44% | 45 | 1.1 | 700 | 13,520 | 50.0% | 40.7% | |
| 47.62% | 42 | 1.3 | 791 | 12,526 | 47.1% | 48.0% | |
| 48.72% | 39 | 1.2 | 660 | 12,047 | 52.9% | 45.5% | |
| 43.75% | 32 | 2.0 | 675 | 11,928 | 57.1% | 33.3% | |
| 54.84% | 31 | 1.0 | 558 | 11,210 | 61.5% | 50.0% | |
| 32.26% | 31 | 0.8 | 575 | 11,341 | 40.0% | 25.0% | |
| 43.33% | 30 | 1.8 | 595 | 10,730 | 53.3% | 33.3% | |
| 58.62% | 29 | 1.1 | 594 | 13,700 | 90.9% | 38.9% | |
| 57.14% | 28 | 1.4 | 631 | 12,526 | 60.0% | 55.6% | |
| 53.57% | 28 | 1.3 | 669 | 12,245 | 53.9% | 53.3% | |
| 37.04% | 27 | 1.2 | 634 | 12,033 | 40.0% | 35.3% | |
| 52.17% | 23 | 1.3 | 668 | 13,503 | 45.5% | 58.3% | |
| 40.91% | 22 | 1.1 | 609 | 12,809 | 33.3% | 46.1% | |
| 45.45% | 22 | 0.9 | 647 | 12,568 | 37.5% | 50.0% | |
| 40.00% | 20 | 4.2 | 877 | 13,590 | 50.0% | 33.3% | |
| 55.00% | 20 | 1.0 | 639 | 12,167 | 44.4% | 63.6% | |
| 66.67% | 18 | 1.1 | 678 | 12,924 | 75.0% | 60.0% | |
| 61.11% | 18 | 1.2 | 647 | 13,816 | 71.4% | 54.5% | |
| 52.94% | 17 | 3.8 | 598 | 11,778 | 33.3% | 75.0% | |
| 75.00% | 16 | 0.9 | 620 | 11,987 | 62.5% | 87.5% | |
| 50.00% | 16 | 0.8 | 581 | 11,670 | 62.5% | 37.5% | |
| 53.33% | 15 | 3.7 | 984 | 11,860 | 57.1% | 50.0% | |
| 66.67% | 15 | 1.1 | 797 | 12,537 | 77.8% | 50.0% | |
| 60.00% | 15 | 1.7 | 729 | 14,524 | 75.0% | 54.5% | |
| 35.71% | 14 | 3.0 | 688 | 9,583 | 12.5% | 66.7% | |
| 78.57% | 14 | 5.2 | 864 | 12,224 | 77.8% | 80.0% | |
| 46.15% | 13 | 1.1 | 704 | 12,661 | 57.1% | 33.3% | |
| 23.08% | 13 | 1.0 | 609 | 12,122 | 20.0% | 25.0% | |
| 61.54% | 13 | 1.9 | 683 | 11,121 | 57.1% | 66.7% | |
| 46.15% | 13 | 0.8 | 704 | 12,327 | 60.0% | 37.5% | |
| 30.77% | 13 | 1.0 | 541 | 10,158 | 33.3% | 28.6% | |
| 58.33% | 12 | 5.2 | 862 | 11,593 | 40.0% | 71.4% | |
| 33.33% | 12 | 2.5 | 741 | 13,058 | 75.0% | 12.5% | |
| 58.33% | 12 | 3.1 | 866 | 14,522 | 50.0% | 60.0% | |
| 70.00% | 10 | 0.9 | 652 | 12,564 | 75.0% | 66.7% | |
| 44.44% | 9 | 6.1 | 822 | 9,868 | 40.0% | 50.0% | |
| 44.44% | 9 | 5.6 | 780 | 12,907 | 0.0% | 57.1% | |
| 55.56% | 9 | 0.9 | 712 | 13,686 | 50.0% | 57.1% | |
| 22.22% | 9 | 1.6 | 724 | 12,814 | 25.0% | 20.0% | |
| 77.78% | 9 | 1.5 | 756 | 14,025 | 75.0% | 80.0% | |
| 25.00% | 8 | 6.3 | 748 | 10,302 | 25.0% | 25.0% | |
| 12.50% | 8 | 0.9 | 592 | 10,132 | 0.0% | 33.3% | |
| 100.00% | 8 | 2.0 | 1,004 | 14,956 | 100.0% | 100.0% | |
| 62.50% | 8 | 3.7 | 822 | 15,597 | 100.0% | 57.1% | |
| 25.00% | 8 | 2.2 | 587 | 11,400 | 33.3% | 20.0% | |
| 50.00% | 8 | 5.7 | 966 | 12,571 | 100.0% | 33.3% | |
| 42.86% | 7 | 1.0 | 530 | 13,853 | 50.0% | 40.0% | |
| 14.29% | 7 | 2.8 | 675 | 12,416 | 33.3% | 0.0% | |
| 42.86% | 7 | 0.8 | 667 | 11,135 | 33.3% | 50.0% | |
| 83.33% | 6 | 2.5 | 613 | 14,764 | 100.0% | 80.0% | |
| 50.00% | 6 | 5.2 | 595 | 11,846 | 33.3% | 66.7% | |
| 16.67% | 6 | 0.8 | 327 | 4,769 | 16.7% | 0.0% | |
| 33.33% | 6 | 0.5 | 566 | 9,280 | 0.0% | 66.7% | |
| 16.67% | 6 | 6.5 | 856 | 11,760 | 33.3% | 0.0% | |
| 16.67% | 6 | 5.1 | 561 | 11,431 | 0.0% | 20.0% | |
| 33.33% | 6 | 6.3 | 975 | 13,093 | 33.3% | 33.3% | |
| 60.00% | 5 | 3.8 | 544 | 9,891 | 33.3% | 100.0% | |
| 40.00% | 5 | 3.1 | 605 | 12,142 | 50.0% | 33.3% | |
| 80.00% | 5 | 6.8 | 764 | 13,879 | 50.0% | 100.0% | |
| 60.00% | 5 | 6.8 | 900 | 11,413 | 66.7% | 50.0% | |
| 60.00% | 5 | 5.4 | 1,043 | 10,840 | 50.0% | 66.7% | |
| 80.00% | 5 | 1.2 | 643 | 14,177 | 100.0% | 66.7% | |
| 80.00% | 5 | 0.6 | 448 | 11,160 | 100.0% | 66.7% | |
| 40.00% | 5 | 1.0 | 749 | 16,164 | 0.0% | 40.0% | |
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Warwick vs Vayne - Frequently Asked Questions
How does Warwick do against Vayne in League of Legends?
Vayne wins the Warwick vs Vayne matchup with a 75.0% win rate compared to Warwick's 25.0%, a 50.0 percentage point difference. This data is based on 8 recent ranked games in patch 26.9.
How does Warwick do against Vayne in the early game?
In the early game, Vayne has the advantage against Warwick with a 66.7% win rate versus 33.3%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Warwick do against Vayne in the late game?
In the late game, Vayne takes over the Warwick vs Vayne matchup with a 80.0% win rate compared to 20.0%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Warwick vs Vayne matchup?
Vayne wins the matchup against Warwick with a 75.0% win rate in League of Legends patch 26.9. The 50.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 8 games analyzed.
What is the best Warwick build against Vayne?
The best Warwick build against Vayne includes Titanic Hydra, Blade of The Ruined King, Thornmail with Mercury's Treads. Check the matchup breakdown above for the full item path and build order.
What are the best Warwick runes against Vayne?
The best Warwick runes against Vayne use the Precision primary tree with Sorcery secondary. This rune setup achieves a 50.0% win rate in the Warwick vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Warwick counter Vayne?
No, Warwick struggles against Vayne with only a 25.0% win rate. Vayne has the advantage in this matchup. Warwick players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.
How do I play Warwick against Vayne?
When playing Warwick against Vayne, play cautiously and avoid Vayne's power spikes. Look for jungle assistance and team-dependent plays since Vayne has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.