
Vaynevs Warwick
Vayne vs Warwick is a decisive matchup in LoL patch 26.9. Vayne wins with a 75.0% win rate (+50.0%) over Warwick based on 8 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Warwick matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Warwick Matchup?

Vayne vs Warwick Matchup Summary
The Vayne vs Warwick matchup is a decisive matchup in League of Legends ranked play. Based on 8 recent matches analyzed, Vayne wins with a 75.0% win rate compared to Warwick's 25.0%, giving Vayne a 50.0 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Warwick players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Warwick leads by 1,026 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Warwick and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Warwick away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Warwick Laning Phase Breakdown
Warwick is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Warwick holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.
Best Vayne Build Against Warwick
Boots of Swiftness is the optimal boots choice against Warwick, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Warwick are Essence Reaver, Mortal Reminder and Infinity Edge. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Warwick. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Warwick matchup.
Early Game vs Late Game
Vayne dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Warwick. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Vayne is far superior in the late game (25+ minutes), boasting a 80.0% win rate — 60.0 points above Warwick. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Warwick players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Vayne Runes Against Warwick
Running Precision primary with Domination secondary allows Vayne to press their advantage against Warwick, amplifying the strengths that make this a favorable matchup.
Vayne matchup data for League of Legends patch 26.9. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 43.36% | 143 | 6.1 | 734 | 12,788 | 43.9% | 43.0% | |
| 48.09% | 131 | 6.0 | 813 | 12,686 | 44.8% | 50.7% | |
| 47.11% | 121 | 6.5 | 798 | 12,793 | 51.8% | 43.1% | |
| 41.59% | 113 | 5.8 | 748 | 12,061 | 44.0% | 39.7% | |
| 47.75% | 111 | 6.1 | 835 | 12,492 | 45.6% | 50.0% | |
| 48.11% | 106 | 6.2 | 779 | 12,949 | 45.8% | 50.0% | |
| 50.52% | 97 | 6.1 | 873 | 13,223 | 50.0% | 50.9% | |
| 62.34% | 78 | 6.3 | 875 | 13,968 | 61.8% | 62.8% | |
| 58.33% | 48 | 6.5 | 932 | 12,568 | 61.9% | 55.6% | |
| 39.58% | 48 | 6.1 | 843 | 12,292 | 38.1% | 40.7% | |
| 39.53% | 43 | 6.1 | 885 | 13,454 | 15.8% | 58.3% | |
| 38.89% | 36 | 6.4 | 770 | 12,727 | 50.0% | 30.0% | |
| 42.86% | 35 | 5.7 | 894 | 13,039 | 50.0% | 38.1% | |
| 47.06% | 34 | 5.9 | 713 | 11,987 | 40.0% | 52.6% | |
| 40.63% | 32 | 5.8 | 655 | 11,878 | 29.4% | 53.3% | |
| 42.86% | 28 | 6.6 | 854 | 14,309 | 36.4% | 47.1% | |
| 46.15% | 26 | 6.0 | 953 | 12,878 | 41.7% | 50.0% | |
| 42.31% | 26 | 6.4 | 799 | 12,511 | 41.7% | 42.9% | |
| 40.00% | 25 | 6.0 | 775 | 12,775 | 20.0% | 53.3% | |
| 44.00% | 25 | 5.6 | 537 | 10,450 | 30.8% | 58.3% | |
| 75.00% | 24 | 6.3 | 897 | 13,780 | 72.7% | 76.9% | |
| 40.91% | 22 | 6.1 | 642 | 9,683 | 20.0% | 58.3% | |
| 63.64% | 22 | 6.2 | 810 | 12,487 | 60.0% | 66.7% | |
| 68.42% | 19 | 5.7 | 1,000 | 14,842 | 25.0% | 80.0% | |
| 38.89% | 18 | 6.2 | 740 | 11,131 | 50.0% | 30.0% | |
| 47.06% | 17 | 6.1 | 951 | 13,193 | 60.0% | 41.7% | |
| 64.71% | 17 | 7.1 | 1,065 | 10,248 | 58.3% | 80.0% | |
| 43.75% | 16 | 6.2 | 839 | 13,392 | 50.0% | 40.0% | |
| 43.75% | 16 | 6.3 | 978 | 11,688 | 57.1% | 33.3% | |
| 46.67% | 15 | 5.8 | 858 | 11,744 | 33.3% | 55.6% | |
| 66.67% | 15 | 6.5 | 901 | 9,318 | 66.7% | 66.7% | |
| 66.67% | 15 | 6.0 | 920 | 10,909 | 42.9% | 87.5% | |
| 53.33% | 15 | 6.5 | 1,018 | 12,465 | 62.5% | 42.9% | |
| 66.67% | 15 | 6.9 | 1,307 | 15,281 | 66.7% | 66.7% | |
| 23.08% | 13 | 6.0 | 1,018 | 12,916 | 60.0% | 0.0% | |
| 46.15% | 13 | 5.5 | 682 | 11,449 | 37.5% | 60.0% | |
| 53.85% | 13 | 6.4 | 903 | 13,034 | 66.7% | 42.9% | |
| 50.00% | 12 | 6.2 | 1,024 | 12,710 | 50.0% | 50.0% | |
| 25.00% | 12 | 6.0 | 786 | 11,724 | 25.0% | 25.0% | |
| 50.00% | 12 | 7.2 | 890 | 10,082 | 37.5% | 75.0% | |
| 50.00% | 12 | 6.2 | 833 | 10,207 | 75.0% | 0.0% | |
| 50.00% | 12 | 6.2 | 1,146 | 12,898 | 42.9% | 60.0% | |
| 58.33% | 12 | 6.0 | 842 | 12,178 | 60.0% | 57.1% | |
| 27.27% | 11 | 6.6 | 703 | 9,294 | 14.3% | 50.0% | |
| 54.55% | 11 | 7.3 | 842 | 15,259 | 33.3% | 62.5% | |
| 54.55% | 11 | 6.2 | 697 | 9,842 | 60.0% | 50.0% | |
| 36.36% | 11 | 5.6 | 1,277 | 10,568 | 60.0% | 16.7% | |
| 30.00% | 10 | 5.9 | 967 | 11,113 | 33.3% | 25.0% | |
| 70.00% | 10 | 6.6 | 1,123 | 13,022 | 100.0% | 62.5% | |
| 70.00% | 10 | 6.5 | 971 | 12,452 | 60.0% | 80.0% | |
| 44.44% | 9 | 6.0 | 892 | 14,392 | 50.0% | 40.0% | |
| 55.56% | 9 | 5.7 | 878 | 13,141 | 100.0% | 33.3% | |
| 66.67% | 9 | 5.8 | 953 | 13,931 | 66.7% | 66.7% | |
| 77.78% | 9 | 5.6 | 789 | 15,159 | 0.0% | 77.8% | |
| 44.44% | 9 | 5.6 | 692 | 11,545 | 42.9% | 50.0% | |
| 33.33% | 9 | 6.9 | 807 | 9,640 | 50.0% | 20.0% | |
| 22.22% | 9 | 5.8 | 647 | 8,561 | 33.3% | 0.0% | |
| 55.56% | 9 | 6.3 | 1,042 | 15,532 | 50.0% | 57.1% | |
| 62.50% | 8 | 6.1 | 1,155 | 17,470 | 50.0% | 66.7% | |
| 25.00% | 8 | 6.3 | 949 | 12,245 | 33.3% | 20.0% | |
| 25.00% | 8 | 5.2 | 575 | 9,938 | 50.0% | 16.7% | |
| 75.00% | 8 | 2.2 | 819 | 12,301 | 66.7% | 80.0% | |
| 75.00% | 8 | 5.2 | 556 | 11,556 | 66.7% | 80.0% | |
| 75.00% | 8 | 7.2 | 762 | 8,980 | 100.0% | 33.3% | |
| 75.00% | 8 | 5.8 | 769 | 13,349 | 100.0% | 60.0% | |
| 57.14% | 7 | 6.1 | 747 | 9,520 | 60.0% | 50.0% | |
| 28.57% | 7 | 4.8 | 680 | 10,522 | 33.3% | 25.0% | |
| 71.43% | 7 | 6.3 | 952 | 13,320 | 0.0% | 83.3% | |
| 28.57% | 7 | 5.7 | 706 | 11,261 | 0.0% | 50.0% | |
| 28.57% | 7 | 6.7 | 753 | 11,274 | 25.0% | 33.3% | |
| 57.14% | 7 | 6.8 | 881 | 13,980 | 50.0% | 60.0% | |
| 33.33% | 6 | 5.2 | 524 | 11,047 | 0.0% | 50.0% | |
| 50.00% | 6 | 5.9 | 760 | 9,989 | 33.3% | 66.7% | |
| 66.67% | 6 | 5.3 | 699 | 9,091 | 75.0% | 50.0% | |
| 66.67% | 6 | 6.8 | 963 | 13,360 | 100.0% | 50.0% | |
| 33.33% | 6 | 4.7 | 630 | 12,375 | 0.0% | 33.3% | |
| 16.67% | 6 | 5.6 | 739 | 11,473 | 0.0% | 50.0% | |
| 66.67% | 6 | 6.4 | 867 | 11,482 | 50.0% | 100.0% | |
| 33.33% | 6 | 4.4 | 964 | 12,794 | 0.0% | 40.0% | |
| 16.67% | 6 | 5.2 | 585 | 8,264 | 0.0% | 50.0% | |
| 33.33% | 6 | 6.1 | 904 | 14,266 | 0.0% | 50.0% | |
| 20.00% | 5 | 5.9 | 1,053 | 13,565 | 0.0% | 33.3% | |
| 60.00% | 5 | 6.9 | 1,233 | 10,730 | 0.0% | 100.0% | |
| 40.00% | 5 | 6.3 | 811 | 11,359 | 100.0% | 25.0% | |
| 20.00% | 5 | 5.9 | 886 | 12,734 | 0.0% | 33.3% | |
| 40.00% | 5 | 6.3 | 1,132 | 14,904 | 100.0% | 25.0% | |
| 0.00% | 5 | 7.1 | 853 | 13,227 | 0.0% | 0.0% | |
| 60.00% | 5 | 6.6 | 1,088 | 16,120 | 50.0% | 66.7% | |
| 40.00% | 5 | 6.8 | 783 | 9,690 | 66.7% | 0.0% | |
| 40.00% | 5 | 1.0 | 795 | 13,189 | 0.0% | 66.7% | |
| 60.00% | 5 | 6.2 | 1,213 | 14,963 | 0.0% | 75.0% | |
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Vayne vs Warwick - Frequently Asked Questions
How does Vayne do against Warwick in League of Legends?
Vayne wins the Vayne vs Warwick matchup with a 75.0% win rate compared to Warwick's 25.0%, a 50.0 percentage point difference. This data is based on 8 recent ranked games in patch 26.9.
How does Vayne do against Warwick in the early game?
In the early game, Vayne has the advantage against Warwick with a 66.7% win rate versus 33.3%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Warwick in the late game?
In the late game, Vayne takes over the Vayne vs Warwick matchup with a 80.0% win rate compared to 20.0%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Warwick matchup?
Vayne wins the matchup against Warwick with a 75.0% win rate in League of Legends patch 26.9. The 50.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 8 games analyzed.
What is the best Vayne build against Warwick?
The best Vayne build against Warwick includes Essence Reaver, Mortal Reminder, Infinity Edge with Boots of Swiftness. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Warwick?
The best Vayne runes against Warwick use the Precision primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Warwick matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Warwick?
Yes, Vayne has a favorable matchup against Warwick with a 75.0% win rate. Vayne strongly counters Warwick in lane based on current patch 26.9 data.
How do I play Vayne against Warwick?
When playing Vayne against Warwick, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
