Afterlife•Skill

Is Afterlife good in Slay the Spire 2?

Afterlife is a common Necrobinder skill in Slay the Spire 2. In combat it resolves as: Summon 6. It ranks among the strongest cards its class can draft right now, earning a spot at B tier in our Slay the Spire 2 card tier list.

Across 122 recorded runs, decks running it win 37.5% of the time, comfortably clear of the 18.9% average, by 18.6%. It’s a more selective pick, turning up in just 3.2% of decks that could run it. Defect players keep it in 0.2% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.3 times in the decks that take it.

It performs best next to Borrowed Time — together they post a +19.8% swing in win rate. It also has strong chemistry with the relic Unceasing Top, which moves its win rate by +24.3%. At 1 energy, it’s upgraded in 31.3% of runs and usually joins the deck around floor 12.

Upgraded, it gains +3 Summon, which is why so many decks invest a rest-site upgrade in it. That’s 36 wins, 60 deaths, and 26 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Decimillipede Elite, which closes out 4.1% of its appearances. Read on for Afterlife’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Necrobinder run.

Best Cards to Pair with Afterlife

Ranked by win-rate lift, Afterlife performs best alongside Borrowed Time (+19.8%), Mad Science (+16.7%), and Spur (+16.3%).

Borrowed Time+19.8%16 runsMad Science+16.7%8 runsSpur+16.3%28 runsDebilitate+16.3%11 runsHang+16.3%12 runsGlimpse Beyond+14.4%4 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Afterlife Win Rate by Class

Afterlife is played across 2 classes, led by Defect (100.0%) and Necrobinder (36.8%) by win rate.

The Defect100.0%1 runsThe Necrobinder36.8%121 runs

Best Relics for Afterlife

Afterlife pairs best with the relics Unceasing Top (+24.3%), Fragrant Mushroom (+23.4%), and Tiny Mailbox (+22.2%), ranked by win-rate lift.

Unceasing Top+24.3%9 runsFragrant Mushroom+23.4%6 runsTiny Mailbox+22.2%8 runsVenerable Tea Set+21.3%10 runsGame Piece+20.8%5 runsJoss Paper+19.9%8 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Afterlife Card Details

Afterlife is a common skill costing 1 energy; it’s upgraded in 31.3% of runs and usually picked up by floor 12.

Summon 6.

Upgrade: +3 Summon

What Ends Runs with Afterlife

Afterlife’s most common run-enders are Decimillipede Elite (4.1%), Kaiser Crab Boss (3.3%), and Knowledge Demon Boss (3.3%).

• Decimillipede Elite4.1% of runs
• Kaiser Crab Boss3.3% of runs
• Knowledge Demon Boss3.3% of runs
• Terror Eel Elite2.5% of runs
• Bygone Effigy Elite2.5% of runs

See Also

Compare Afterlife with the rest of the best Slay the Spire 2 cards, relics, and classes below.