Afterlife•Skill

Is Afterlife good in Slay the Spire 2?

Afterlife is a common Necrobinder skill in Slay the Spire 2. In combat it resolves as: Summon 6. It ranks among the strongest cards its class can draft right now, earning a spot at S tier in our Slay the Spire 2 card tier list.

Across 29 recorded runs, decks running it win 37.5% of the time, comfortably clear of the 12.6% average, by 24.9%. It’s a more selective pick, turning up in just 5.6% of decks that could run it. Necrobinder players keep it in 16.9% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.3 times in the decks that take it.

It performs best next to Hang — together they post a +62.5% swing in win rate. It also has strong chemistry with the relic Unceasing Top, which moves its win rate by +62.5%. At 1 energy, it’s upgraded in 27.0% of runs and usually joins the deck around floor 12.

Upgraded, it gains +3 Summon, which is why so many decks invest a rest-site upgrade in it. That’s 9 wins, 15 deaths, and 5 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Terror Eel Elite, which closes out 6.9% of its appearances. Read on for Afterlife’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Necrobinder run.

Best Cards to Pair with Afterlife

Ranked by win-rate lift, Afterlife performs best alongside Hang (+62.5%), Oblivion (+62.5%), and Fetch (+62.5%).

Hang+62.5%3 runsOblivion+62.5%4 runsFetch+62.5%4 runsCalcify+37.5%4 runsDevour Life+37.5%4 runsUndeath+37.5%4 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Afterlife Win Rate by Class

Afterlife is drafted only by the Necrobinder, where it holds a 37.5% win rate across 29 runs.

The Necrobinderappears in 16.9% of its runs (29 tracked)

Best Relics for Afterlife

Afterlife pairs best with the relics Unceasing Top (+62.5%), Sparkling Rouge (+62.5%), and Fragrant Mushroom (+62.5%), ranked by win-rate lift.

Unceasing Top+62.5%4 runsSparkling Rouge+62.5%3 runsFragrant Mushroom+62.5%3 runsStrike Dummy+45.8%6 runsGremlin Horn+37.5%4 runsJeweled Mask+29.2%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Afterlife Card Details

Afterlife is a common skill costing 1 energy; it’s upgraded in 27.0% of runs and usually picked up by floor 12.

Summon 6.

Upgrade: +3 Summon

What Ends Runs with Afterlife

Afterlife’s most common run-enders are Terror Eel Elite (6.9%), Bygone Effigy Elite (6.9%), and Doormaker Boss (6.9%).

• Terror Eel Elite6.9% of runs
• Bygone Effigy Elite6.9% of runs
• Doormaker Boss6.9% of runs
• Infested Prisms Elite6.9% of runs

See Also

Compare Afterlife with the rest of the best Slay the Spire 2 cards, relics, and classes below.