Defragment Power

Is Defragment good in Slay the Spire 2?

In Slay the Spire 2, Defragment is a rare power from the Defect card pool. Its effect: Gain 1 Focus. Performance-wise it’s a solid if unspectacular include, rated C tier overall.

Over 346 tracked runs its win rate sits at 26.2%, 12.4% ahead of the 13.8% all-deck baseline. It sees niche play, included in only 1.6% of eligible runs. When it is actually offered players take it 47.2% of the time, and that looks correct: those runs win 29.0% against 26.5% for runs that passed, a +2.5% pick lift over 286 decided runs. Within Defect runs it’s drafted 7.5% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.2 copies on average.

Its standout pairing so far is Machine Learning, which lifts its win rate by +21.0% when the two share a deck. On the relic side, Joss Paper is its standout companion, worth a +32.5% win-rate swing alongside it. It costs 1 energy, gets upgraded 36.7% of the time, and tends to be picked up near floor 18.

Of the runs that drafted it, 90 ended in victory against 253 deaths and 3 abandons. Its most common run-ender is Test Subject Boss, finishing 6.4% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Defragment fits a Defect deck.

Pick or Skip: Defragment

Players take Defragment in 47.2% of the 657 offers it appears in; those runs win 29.0% against 26.5% for runs that passed, a pick lift of +2.5% over 286 decided runs.

Taken 310 times out of 657 offers.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

When to Pick Up Defragment

Of the 3 pickup windows recorded for Defragment, Act 2 is the best: 41.4% across 99 runs.

Win rate of runs by the act Defragment entered the deck. Acts that have not reached the sample floor show their run count only.

Best Cards to Pair with Defragment

Defragment’s strongest card pairings so far are Machine Learning (+21.0%), Flak Cannon (+18.1%), and Genetic Algorithm (+17.5%), each shown with the win-rate lift it adds.

Machine Learning+21.0%40 runsFlak Cannon+18.1%23 runsGenetic Algorithm+17.5%44 runsIteration+16.7%38 runsSignal Boost+16.5%50 runsMad Science+15.7%32 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Defragment Win Rate by Class

Exclusive to the Defect, Defragment posts a 26.0% win rate over 342 tracked runs.

The Defectappears in 7.5% of its runs (342 tracked)

Best Relics for Defragment

The relics that swing Defragment’s win rate the most are Joss Paper (+32.5%), Captain's Wheel (+27.0%), and Game Piece (+24.2%), with each lift shown.

Joss Paper+32.5%20 runsCaptain's Wheel+27.0%25 runsGame Piece+24.2%17 runsCloak Clasp+22.5%21 runsOrnamental Fan+22.0%39 runsTiny Mailbox+21.1%23 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Defragment Card Details

A 1-energy rare power, Defragment is upgraded 36.7% of the time and tends to enter the deck around floor 18.

Gain 1 Focus.

What Ends Runs with Defragment

Runs holding Defragment end most often against Test Subject Boss (6.4%), Aeonglass Boss (5.8%), and Kaiser Crab Boss (4.9%) — the share of its runs each accounts for is shown.

• Test Subject Boss6.4% of runs
• Aeonglass Boss5.8% of runs
• Kaiser Crab Boss4.9% of runs
• Infested Prisms Elite4.9% of runs
• Queen Boss4.6% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.