GuiltyCurse
Removed from your Deck after combats.
Is Guilty good in Slay the Spire 2?
Guilty is a curse Curse curse in Slay the Spire 2. In combat it resolves as: Removed from your Deck after combats. It currently underperforms most alternatives, sitting at F tier in our Slay the Spire 2 card rankings.
Across 37 recorded runs, decks running it win 0.0% of the time, trailing the 18.9% average by 18.9%. It’s a more selective pick, turning up in just 1.0% of decks that could run it. Necrobinder players keep it in 1.3% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.0 times in the decks that take it.
It performs best next to Astral Pulse — together they post a 0.0% swing in win rate. It also has strong chemistry with the relic Large Capsule, which moves its win rate by 0.0%. At - energy, it’s upgraded in 0.0% of runs and usually joins the deck around floor 7.
That’s 0 wins, 24 deaths, and 13 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Phrog Parasite Elite, which closes out 16.2% of its appearances. Read on for Guilty’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Curse run.
Guilty Win Rate & Pick Rate
Guilty’s 0.0% win rate trails the 18.9% all-deck average by 18.9%, the gap charted below.
Run Outcomes with Guilty
Guilty has 0 wins and 37 losses over 37 tracked runs (0.0% won); abandoned runs count as losses.
- Wins 0.0%
- Losses 100.0%
Best Cards to Pair with Guilty
Ranked by win-rate lift, Guilty performs best alongside Astral Pulse (0.0%), Bash (0.0%), and Blade Dance (0.0%).
Astral Pulse3 runs
Bash4 runs
Blade Dance3 runs
Bloodletting3 runs
Bodyguard11 runs
Ascender's Bane15 runsBased on small co-occurring samples — treat these as early signals, not final verdicts.
Guilty Win Rate by Class
Guilty is played across 5 classes, led by Necrobinder (0.0%), Silent (0.0%), and Regent (0.0%) by win rate.
Best Relics for Guilty
Guilty pairs best with the relics Large Capsule (0.0%), Neow's Bones (0.0%), and Pomander (0.0%), ranked by win-rate lift.
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Guilty Card Details
Guilty is a curse curse costing - energy; it’s upgraded in 0.0% of runs and usually picked up by floor 7.
Removed from your Deck after combats.
What Ends Runs with Guilty
Guilty’s most common run-enders are Phrog Parasite Elite (16.2%), The Kin Boss (8.1%), and Ceremonial Beast Boss (8.1%).
- Phrog Parasite Elite16.2% of runs
- The Kin Boss8.1% of runs
- Ceremonial Beast Boss8.1% of runs
- Bygone Effigy Elite5.4% of runs
- Flyconid Normal5.4% of runs
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Guilty – Frequently Asked Questions
Is Guilty good in Slay the Spire 2?
Across 37 tracked runs, Guilty has a 0.0% win rate — +18.9% below the average deck. Win rate reflects how often runs that include the card end in victory.
What does Guilty do in Slay the Spire 2?
Guilty costs - energy. Removed from your Deck after combats.
What class is Guilty in Slay the Spire 2?
Guilty is a Curse Curse Curse.
Is Guilty worth upgrading in Slay the Spire 2?
Guilty can be upgraded at a rest site to improve its effect.
What is the best relic for Guilty?
In tracked runs, Guilty has performed best alongside Large Capsule, which lifts its win rate by 0.0% over 6 runs together.
See Also
Compare Guilty with the rest of the best Slay the Spire 2 cards, relics, and classes below.