Royal Gamble•Skill

Is Royal Gamble good in Slay the Spire 2?

Royal Gamble is an uncommon Regent skill in Slay the Spire 2. In combat it resolves as: Gain. It’s a dependable, middle-of-the-pack option, landing at C tier in our rankings.

Across 28 recorded runs, decks running it win 21.4% of the time, comfortably clear of the 12.6% average, by 8.8%. It’s a more selective pick, turning up in just 5.4% of decks that could run it. Regent players keep it in 16.9% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.2 times in the decks that take it.

It performs best next to Glow — together they post a +53.6% swing in win rate. It also has strong chemistry with the relic Happy Flower, which moves its win rate by +78.6%. At 0 energy, it’s upgraded in 15.2% of runs and usually joins the deck around floor 13.

That’s 6 wins, 22 deaths, and 0 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Terror Eel Elite, which closes out 10.7% of its appearances. Read on for Royal Gamble’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Regent run.

Best Cards to Pair with Royal Gamble

Ranked by win-rate lift, Royal Gamble performs best alongside Glow (+53.6%), Spoils of Battle (+53.6%), and Orbit (+53.6%).

Glow+53.6%8 runsSpoils of Battle+53.6%4 runsOrbit+53.6%4 runsHidden Cache+45.2%6 runsBig Bang+45.2%3 runsBundle of Joy+45.2%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Royal Gamble Win Rate by Class

Royal Gamble is drafted only by the Regent, where it holds a 21.4% win rate across 28 runs.

The Regentappears in 16.9% of its runs (28 tracked)

Best Relics for Royal Gamble

Royal Gamble pairs best with the relics Happy Flower (+78.6%), Lantern (+78.6%), and War Paint (+58.6%), ranked by win-rate lift.

Happy Flower+78.6%3 runsLantern+78.6%3 runsWar Paint+58.6%5 runsPendulum+58.6%5 runsBag of Marbles+45.2%3 runsFestive Popper+45.2%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Royal Gamble Card Details

Royal Gamble is an uncommon skill costing 0 energy; it’s upgraded in 15.2% of runs and usually picked up by floor 13.

Gain.

What Ends Runs with Royal Gamble

Royal Gamble’s most common run-enders are Terror Eel Elite (10.7%), Vantom Boss (10.7%), and Decimillipede Elite (7.1%).

• Terror Eel Elite10.7% of runs
• Vantom Boss10.7% of runs
• Decimillipede Elite7.1% of runs
• The Kin Boss7.1% of runs
• Phrog Parasite Elite7.1% of runs

See Also

Compare Royal Gamble with the rest of the best Slay the Spire 2 cards, relics, and classes below.