Arsenal•Power

Is Arsenal good in Slay the Spire 2?

Arsenal is a rare Regent power in Slay the Spire 2. In combat it resolves as: Whenever you create a card, gain 1 Strength. It ranks among the strongest cards its class can draft right now, earning a spot at S tier in our Slay the Spire 2 card tier list.

Across 32 recorded runs, decks running it win 42.9% of the time, comfortably clear of the 18.9% average, by 23.9%. It’s a more selective pick, turning up in just 0.8% of decks that could run it. Regent players keep it in 4.7% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.1 times in the decks that take it.

It performs best next to Devastate — together they post a +16.3% swing in win rate. It also has strong chemistry with the relic Centennial Puzzle, which moves its win rate by +19.8%. At 1 energy, it’s upgraded in 65.7% of runs and usually joins the deck around floor 18.

That’s 12 wins, 16 deaths, and 4 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Entomancer Elite, which closes out 9.4% of its appearances. Read on for Arsenal’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Regent run.

Best Cards to Pair with Arsenal

Ranked by win-rate lift, Arsenal performs best alongside Devastate (+16.3%), Solar Strike (+15.2%), and Convergence (+15.2%).

Devastate+16.3%4 runsSolar Strike+15.2%7 runsConvergence+15.2%6 runsBulwark+15.2%6 runsHeirloom Hammer+13.2%3 runsHegemony+13.2%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Arsenal Win Rate by Class

Arsenal is drafted only by the Regent, where it holds a 42.9% win rate across 32 runs.

The Regentappears in 4.7% of its runs (32 tracked)

Best Relics for Arsenal

Arsenal pairs best with the relics Centennial Puzzle (+19.8%), Regal Pillow (+15.2%), and Pear (+13.2%), ranked by win-rate lift.

Centennial Puzzle+19.8%8 runsRegal Pillow+15.2%7 runsPear+13.2%3 runsVajra+13.2%4 runsGorget+13.2%3 runsMiniature Cannon+13.2%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Arsenal Card Details

Arsenal is a rare power costing 1 energy; it’s upgraded in 65.7% of runs and usually picked up by floor 18.

Whenever you create a card, gain 1 Strength.

What Ends Runs with Arsenal

Arsenal’s most common run-enders are Entomancer Elite (9.4%), Decimillipede Elite (6.3%), and Terror Eel Elite (6.3%).

• Entomancer Elite9.4% of runs
• Decimillipede Elite6.3% of runs
• Terror Eel Elite6.3% of runs
• Knowledge Demon Boss6.3% of runs
• Test Subject Boss6.3% of runs

See Also

Compare Arsenal with the rest of the best Slay the Spire 2 cards, relics, and classes below.