Sacrifice Skill

Is Sacrifice good in Slay the Spire 2?

In Slay the Spire 2, Sacrifice is a rare skill from the Necrobinder card pool. Its effect: If Osty is alive, he dies and you gain Block equal to double his Max HP. The data flags it as a weaker pick, settling at D tier — usually one to pass on unless your deck specifically wants it.

Over 74 tracked runs its win rate sits at 19.2%, 5.7% ahead of the 13.4% all-deck baseline. It sees niche play, included in only 0.5% of eligible runs. Offer data argues the other way: taken 12.3% of the time it is shown, runs that picked it win 24.5% against 35.0% for runs that passed — a -8.8% pick lift across 53 decided runs. Within Necrobinder runs it’s drafted 2.5% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.0 copies on average.

Its standout pairing so far is Wisp, which lifts its win rate by +12.8% when the two share a deck. On the relic side, Strawberry is its standout companion, worth a +6.4% win-rate swing alongside it. It costs 1 energy, gets upgraded 30.3% of the time, and tends to be picked up near floor 15.

Upgrading the card adds -1 EnergyCost to its stat line. Of the runs that drafted it, 14 ended in victory against 59 deaths and 1 abandons. Its most common run-ender is Test Subject Boss, finishing 9.5% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Sacrifice fits a Necrobinder deck.

Pick or Skip: Sacrifice

Players take Sacrifice in 12.3% of the 448 offers it appears in; those runs win 24.5% against 35.0% for runs that passed, a pick lift of -8.8% over 53 decided runs.

Taken 55 times out of 448 offers.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

When to Pick Up Sacrifice

Of the 2 pickup windows recorded for Sacrifice, Act 2 is the best: 36.8% across 19 runs.

Win rate of runs by the act Sacrifice entered the deck. Acts that have not reached the sample floor show their run count only.

Best Cards to Pair with Sacrifice

Sacrifice’s strongest card pairings so far are Wisp (+12.8%), Invoke (+10.9%), and Defy (+10.6%), each shown with the win-rate lift it adds.

Wisp+12.8%21 runsInvoke+10.9%24 runsDefy+10.6%30 runsNegative Pulse+8.8%29 runsDebilitate+8.5%15 runsDeathbringer+8.1%19 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Sacrifice Win Rate by Class

Exclusive to the Necrobinder, Sacrifice posts a 19.4% win rate over 73 tracked runs.

The Necrobinderappears in 2.5% of its runs (73 tracked)

Best Relics for Sacrifice

The relics that swing Sacrifice’s win rate the most are Strawberry (+6.4%), Bound Phylactery (+0.2%), and Arcane Scroll (-7.5%), with each lift shown.

Strawberry+6.4%17 runsBound Phylactery+0.2%68 runsArcane Scroll-7.5%16 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Sacrifice Card Details

A 1-energy rare skill, Sacrifice is upgraded 30.3% of the time and tends to enter the deck around floor 15.

If Osty is alive, he dies and you gain Block equal to double his Max HP.

Upgrade: -1 EnergyCost

What Ends Runs with Sacrifice

Runs holding Sacrifice end most often against Test Subject Boss (9.5%), Knowledge Demon Boss (8.1%), and Slumbering Beetle Normal (6.8%) — the share of its runs each accounts for is shown.

• Test Subject Boss9.5% of runs
• Knowledge Demon Boss8.1% of runs
• Slumbering Beetle Normal6.8% of runs
• Decimillipede Elite5.4% of runs
• Kaiser Crab Boss5.4% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.