Defy•Skill

Is Defy good in Slay the Spire 2?

Defy is a common Necrobinder skill in Slay the Spire 2. In combat it resolves as: Gain 6 Block. Apply 1 Weak. It currently underperforms most alternatives, sitting at D tier in our Slay the Spire 2 card rankings.

Across 216 recorded runs, decks running it win 27.1% of the time, comfortably clear of the 18.9% average, by 8.2%. It’s a more selective pick, turning up in just 5.7% of decks that could run it. Silent players keep it in 0.1% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.4 times in the decks that take it.

It performs best next to Demesne — together they post a +27.6% swing in win rate. It also has strong chemistry with the relic Bag of Preparation, which moves its win rate by +26.9%. At 1 energy, it’s upgraded in 30.7% of runs and usually joins the deck around floor 11.

Upgraded, it gains +3 Block, which is why so many decks invest a rest-site upgrade in it. That’s 51 wins, 137 deaths, and 28 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Test Subject Boss, which closes out 5.6% of its appearances. Read on for Defy’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Necrobinder run.

Best Cards to Pair with Defy

Ranked by win-rate lift, Defy performs best alongside Demesne (+27.6%), Glimpse Beyond (+21.3%), and Master of Strategy (+20.8%).

Demesne+27.6%29 runsGlimpse Beyond+21.3%9 runsMaster of Strategy+20.8%4 runsRegret+20.8%4 runsAfterlife+20.7%34 runsSpirit of Ash+20.3%21 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Defy Win Rate by Class

Defy is played across 4 classes, led by Silent (100.0%), Necrobinder (27.2%), and Ironclad (0.0%) by win rate.

The Silent100.0%1 runsThe Necrobinder27.2%211 runsThe Ironclad0.0%3 runsThe Defect0.0%1 runs

Best Relics for Defy

Defy pairs best with the relics Bag of Preparation (+26.9%), Potion Belt (+26.0%), and Tiny Mailbox (+21.9%), ranked by win-rate lift.

Bag of Preparation+26.9%35 runsPotion Belt+26.0%31 runsTiny Mailbox+21.9%19 runsPocketwatch+21.1%6 runsAnchor+20.9%34 runsFestive Popper+20.9%30 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Defy Card Details

Defy is a common skill costing 1 energy; it’s upgraded in 30.7% of runs and usually picked up by floor 11.

Gain 6 Block. Apply 1 Weak.

Upgrade: +3 Block

What Ends Runs with Defy

Defy’s most common run-enders are Test Subject Boss (5.6%), Decimillipede Elite (4.6%), and Knowledge Demon Boss (4.6%).

• Test Subject Boss5.6% of runs
• Decimillipede Elite4.6% of runs
• Knowledge Demon Boss4.6% of runs
• Infested Prisms Elite3.7% of runs
• Kaiser Crab Boss2.8% of runs

See Also

Compare Defy with the rest of the best Slay the Spire 2 cards, relics, and classes below.