
Sleight of FleshPower
Whenever you apply a debuff to an enemy, they take 9 damage.
Is Sleight of Flesh good in Slay the Spire 2?
In Slay the Spire 2, Sleight of Flesh is an uncommon power from the Necrobinder card pool. Its effect: Whenever you apply a debuff to an enemy, they take 9 damage. Performance-wise it’s a solid if unspectacular include, rated C tier overall.
Over 25 tracked runs its win rate sits at 17.4%, 4.8% ahead of the 12.6% all-deck baseline. It sees niche play, included in only 4.8% of eligible runs. Within Necrobinder runs it’s drafted 14.5% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.1 copies on average.
Its standout pairing so far is Dirge, which lifts its win rate by +82.6% when the two share a deck. On the relic side, Strike Dummy is its standout companion, worth a +49.3% win-rate swing alongside it. It costs 2 energy, gets upgraded 18.5% of the time, and tends to be picked up near floor 10.
Of the runs that drafted it, 4 ended in victory against 19 deaths and 2 abandons. Its most common run-ender is Phrog Parasite Elite, finishing 12.0% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Sleight of Flesh fits a Necrobinder deck.
Sleight of Flesh Win Rate & Pick Rate
At a 17.4% win rate, Sleight of Flesh runs 4.8% ahead of the 12.6% all-deck baseline — the bars below put the two side by side.
Run Outcomes with Sleight of Flesh
Across the 25 tracked runs that drafted Sleight of Flesh, 4 ended in a win and 21 in a loss — a 16.0% win share, counting abandons as losses.
- Wins 16.0%
- Losses 84.0%
Sleight of Flesh Win Rate by Class
Exclusive to the Necrobinder, Sleight of Flesh posts a 17.4% win rate over 25 tracked runs.
Best Relics for Sleight of Flesh
The relics that swing Sleight of Flesh’s win rate the most are Strike Dummy (+49.3%), Strawberry (+49.3%), and Sparkling Rouge (+49.3%), with each lift shown.
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Sleight of Flesh Card Details
A 2-energy uncommon power, Sleight of Flesh is upgraded 18.5% of the time and tends to enter the deck around floor 10.
Whenever you apply a debuff to an enemy, they take 9 damage.
What Ends Runs with Sleight of Flesh
Runs holding Sleight of Flesh end most often against Phrog Parasite Elite (12.0%), Entomancer Elite (8.0%), and Slumbering Beetle Normal (8.0%) — the share of its runs each accounts for is shown.
- Phrog Parasite Elite12.0% of runs
- Entomancer Elite8.0% of runs
- Slumbering Beetle Normal8.0% of runs
- Byrdonis Elite8.0% of runs
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Sleight of Flesh – Frequently Asked Questions
Is Sleight of Flesh good in Slay the Spire 2?
Across 25 tracked runs, Sleight of Flesh has a 17.4% win rate — +4.8% above the average deck. Win rate reflects how often runs that include the card end in victory.
What does Sleight of Flesh do in Slay the Spire 2?
Sleight of Flesh costs 2 energy. Whenever you apply a debuff to an enemy, they take 9 damage.
What class is Sleight of Flesh in Slay the Spire 2?
Sleight of Flesh is an Uncommon Necrobinder Power.
Is Sleight of Flesh worth upgrading in Slay the Spire 2?
Sleight of Flesh can be upgraded at a rest site to improve its effect.
What is the best relic for Sleight of Flesh?
In tracked runs, Sleight of Flesh has performed best alongside Strike Dummy, which lifts its win rate by +49.3% over 4 runs together.
See Also
Keep exploring Slay the Spire 2 tier lists and stats below.