Sleight of Flesh Power

Is Sleight of Flesh good in Slay the Spire 2?

In Slay the Spire 2, Sleight of Flesh is an uncommon power from the Necrobinder card pool. Its effect: Whenever you apply a debuff to an enemy, they take 9 damage. Performance-wise it’s a solid if unspectacular include, rated C tier overall.

Over 419 tracked runs its win rate sits at 27.3%, 13.9% ahead of the 13.4% all-deck baseline. It sees niche play, included in only 2.5% of eligible runs. When it is actually offered players take it 23.7% of the time, and that looks correct: those runs win 28.0% against 25.7% for runs that passed, a +2.3% pick lift over 314 decided runs. Within Necrobinder runs it’s drafted 14.3% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.2 copies on average.

Its standout pairing so far is Oblivion, which lifts its win rate by +27.8% when the two share a deck. On the relic side, Eternal Feather is its standout companion, worth a +28.4% win-rate swing alongside it. It costs 2 energy, gets upgraded 38.0% of the time, and tends to be picked up near floor 15.

Of the runs that drafted it, 114 ended in victory against 303 deaths and 2 abandons. Its most common run-ender is Decimillipede Elite, finishing 6.2% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Sleight of Flesh fits a Necrobinder deck.

Pick or Skip: Sleight of Flesh

Players take Sleight of Flesh in 23.7% of the 1479 offers it appears in; those runs win 28.0% against 25.7% for runs that passed, a pick lift of +2.3% over 314 decided runs.

Taken 350 times out of 1479 offers.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

When to Pick Up Sleight of Flesh

Of the 4 pickup windows recorded for Sleight of Flesh, Act 3 is the best: 62.2% across 37 runs.

Win rate of runs by the act Sleight of Flesh entered the deck. Acts that have not reached the sample floor show their run count only.

Best Cards to Pair with Sleight of Flesh

Sleight of Flesh’s strongest card pairings so far are Oblivion (+27.8%), Pagestorm (+24.3%), and Mad Science (+23.4%), each shown with the win-rate lift it adds.

Oblivion+27.8%73 runsPagestorm+24.3%34 runsMad Science+23.4%22 runsSquash+20.3%23 runsTransfigure+19.9%37 runsGlimpse Beyond+19.6%15 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Sleight of Flesh Win Rate by Class

Exclusive to the Necrobinder, Sleight of Flesh posts a 27.5% win rate over 413 tracked runs.

The Necrobinderappears in 14.3% of its runs (413 tracked)

Best Relics for Sleight of Flesh

The relics that swing Sleight of Flesh’s win rate the most are Eternal Feather (+28.4%), Fragrant Mushroom (+27.6%), and Miniature Tent (+26.6%), with each lift shown.

Eternal Feather+28.4%29 runsFragrant Mushroom+27.6%35 runsMiniature Tent+26.6%21 runsBone Flute+24.9%45 runsMiniature Cannon+24.5%30 runsCandelabra+24.4%32 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Sleight of Flesh Card Details

A 2-energy uncommon power, Sleight of Flesh is upgraded 38.0% of the time and tends to enter the deck around floor 15.

Whenever you apply a debuff to an enemy, they take 9 damage.

What Ends Runs with Sleight of Flesh

Runs holding Sleight of Flesh end most often against Decimillipede Elite (6.2%), Aeonglass Boss (5.0%), and Test Subject Boss (5.0%) — the share of its runs each accounts for is shown.

• Decimillipede Elite6.2% of runs
• Aeonglass Boss5.0% of runs
• Test Subject Boss5.0% of runs
• The Insatiable Boss3.8% of runs
• Knowledge Demon Boss3.3% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.