
In Slay the Spire 2, Sleight of Flesh is an uncommon power from the Necrobinder card pool. Its effect: Whenever you apply a debuff to an enemy, they take 9 damage. Performance-wise it’s a solid if unspectacular include, rated C tier overall.
Over 206 tracked runs its win rate sits at 26.8%, 12.4% ahead of the 14.5% all-deck baseline. It sees niche play, included in only 2.3% of eligible runs. Taken 21.6% of the times it is offered, it lands close to neutral on the pick-versus-skip split: 28.8% for runs that took it against 27.5% for runs that passed, a +1.2% pick lift over 153 decided runs. Within Necrobinder runs it’s drafted 12.5% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.2 copies on average.
Its standout pairing so far is Oblivion, which lifts its win rate by +29.9% when the two share a deck. On the relic side, Fragrant Mushroom is its standout companion, worth a +30.7% win-rate swing alongside it. It costs 2 energy, gets upgraded 35.3% of the time, and tends to be picked up near floor 15.
Of the runs that drafted it, 55 ended in victory against 150 deaths and 1 abandons. Its most common run-ender is Decimillipede Elite, finishing 6.3% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Sleight of Flesh fits a Necrobinder deck.
At a 26.8% win rate, Sleight of Flesh runs 12.4% ahead of the 14.5% all-deck baseline — the bars below put the two side by side.
Across the 206 tracked runs that drafted Sleight of Flesh, 55 ended in a win and 151 in a loss — a 26.7% win share, counting abandons as losses.
Players take Sleight of Flesh in 21.6% of the 788 offers it appears in; those runs win 28.8% against 27.5% for runs that passed, a pick lift of +1.2% over 153 decided runs.
Taken 170 times out of 788 offers.
Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.
Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.
Of the 4 pickup windows recorded for Sleight of Flesh, Act 3 is the best: 60.0% across 15 runs.
Win rate of runs by the act Sleight of Flesh entered the deck. Acts that have not reached the sample floor show their run count only.
Exclusive to the Necrobinder, Sleight of Flesh posts a 27.4% win rate over 202 tracked runs.
The relics that swing Sleight of Flesh’s win rate the most are Fragrant Mushroom (+30.7%), Bag of Preparation (+25.2%), and Candelabra (+23.9%), with each lift shown.
A 2-energy uncommon power, Sleight of Flesh is upgraded 35.3% of the time and tends to enter the deck around floor 15.
Whenever you apply a debuff to an enemy, they take 9 damage.
Runs holding Sleight of Flesh end most often against Decimillipede Elite (6.3%), Test Subject Boss (4.9%), and Phrog Parasite Elite (3.4%) — the share of its runs each accounts for is shown.
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Based on small co-occurring samples — treat these as early signals, not final verdicts.
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Across 206 tracked runs, Sleight of Flesh has a 26.8% win rate — +12.4% above the average deck. Win rate reflects how often runs that include the card end in victory.
Sleight of Flesh costs 2 energy. Whenever you apply a debuff to an enemy, they take 9 damage.
Sleight of Flesh is an Uncommon Necrobinder Power.
Sleight of Flesh can be upgraded at a rest site to improve its effect.
In tracked runs, Sleight of Flesh has performed best alongside Fragrant Mushroom, which lifts its win rate by +30.7% over 19 runs together.
Players take Sleight of Flesh in 21.6% of its 788 recorded offers. Runs that picked it win 28.8% (153 decided runs) against 27.5% for runs that skipped it (397 decided runs) — a +1.3% difference, and a +1.2% pick lift once sample size is accounted for.
Whenever you apply a debuff to an enemy, they take 9 damage.