SynthesisAttack
Deal 12 damage. The next Power you play costs 0 -cost.
Is Synthesis good in Slay the Spire 2?
Synthesis is an uncommon Defect attack in Slay the Spire 2. In combat it resolves as: Deal 12 damage. The next Power you play costs 0 -cost. It currently underperforms most alternatives, sitting at D tier in our Slay the Spire 2 card rankings.
Across 2 recorded runs, decks running it win 0.0% of the time, trailing the 12.6% average by 12.6%. It’s a more selective pick, turning up in just 0.4% of decks that could run it. Defect players keep it in 7.1% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.0 times in the decks that take it.
At 2 energy, it’s upgraded in 0.0% of runs and usually joins the deck around floor 4.
Upgraded, it gains +6 Damage, which is why so many decks invest a rest-site upgrade in it. That’s 0 wins, 2 deaths, and 0 abandoned runs with it in the deck. Read on for Synthesis’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Defect run.
Synthesis Win Rate & Pick Rate
Synthesis’s 0.0% win rate trails the 12.6% all-deck average by 12.6%, the gap charted below.
Run Outcomes with Synthesis
Synthesis has 0 wins and 2 losses over 2 tracked runs (0.0% won); abandoned runs count as losses.
- Wins 0.0%
- Losses 100.0%
Synthesis Win Rate by Class
Synthesis is drafted only by the Defect, where it holds a 0.0% win rate across 2 runs.
The Defectappears in 7.1% of its runs (2 tracked)Synthesis Card Details
Synthesis is an uncommon attack costing 2 energy; it’s upgraded in 0.0% of runs and usually picked up by floor 4.
Deal 12 damage. The next Power you play costs 0 -cost.
Upgrade: +6 Damage
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Synthesis – Frequently Asked Questions
Is Synthesis good in Slay the Spire 2?
Across 2 tracked runs, Synthesis has a 0.0% win rate — +12.6% below the average deck. Win rate reflects how often runs that include the card end in victory.
What does Synthesis do in Slay the Spire 2?
Synthesis costs 2 energy. Deal 12 damage. The next Power you play costs 0 -cost.
What class is Synthesis in Slay the Spire 2?
Synthesis is an Uncommon Defect Attack.
Is Synthesis worth upgrading in Slay the Spire 2?
Players upgrade Synthesis in 0.0% of runs. Upgrading it grants +6 Damage.
See Also
Compare Synthesis with the rest of the best Slay the Spire 2 cards, relics, and classes below.