Red MaskRelic
At the start of each combat, apply Weak to ALL enemies.
Is Red Mask good in Slay the Spire 2?
Red Mask is a common relic in Slay the Spire 2. While carried, it does the following: At the start of each combat, apply Weak to ALL enemies. It currently underperforms most relics, sitting at D tier in our Slay the Spire 2 relic rankings.
Across 327 recorded runs, decks carrying it win 35.9% of the time, comfortably clear of the 18.9% average, by 17.0%. It’s a more situational relic, showing up in just 8.6% of runs. The class that gets the most out of it is the Defect, at a 41.1% win rate. Defect players hold onto it in 10.1% of their runs.
It combos especially well with Salvo, worth a +64.1% win-rate swing together. Another strong card to run with it is Prolong, worth +64.1% to its win rate. On average it’s acquired around floor 20 of a run. Its common rarity shapes how frequently you’ll run into it.
It has 106 run wins against 189 losses in our tracked data. When runs carrying it end, the most frequent culprit is Queen Boss, which closes out 6.1% of them. Read on for Red Mask’s complete card, class, and threat breakdown before you decide to pick it up.
Red Mask Win Rate & Pick Rate
Red Mask’s 35.9% win rate clears the 18.9% all-run average by 17.0%, the gap charted below.
Run Outcomes with Red Mask
Red Mask has 106 wins and 221 losses over 327 tracked runs (32.4% won); abandoned runs count as losses.
- Wins 32.4%
- Losses 67.6%
Best Cards with Red Mask
Ranked by win-rate lift, the best cards to run with Red Mask are Salvo (+64.1%), Prolong (+64.1%), and Helix Drill (+64.1%).
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Red Mask Win Rate by Class
Red Mask shows up across 5 classes, led by Defect (41.1%), Silent (40.0%), and Necrobinder (34.5%) by win rate.
Red Mask Details
Red Mask is a common relic carried in 8.6% of runs and usually picked up around floor 20.
At the start of each combat, apply Weak to ALL enemies.
What Ends Runs with Red Mask
Red Mask’s most common run-enders are Queen Boss (6.1%), Test Subject Boss (5.5%), and Knowledge Demon Boss (5.2%).
- Queen Boss6.1% of runs
- Test Subject Boss5.5% of runs
- Knowledge Demon Boss5.2% of runs
- Kaiser Crab Boss3.7% of runs
- Entomancer Elite3.1% of runs
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Red Mask – Frequently Asked Questions
Is Red Mask good in Slay the Spire 2?
Across 327 tracked runs carrying it, Red Mask wins 35.9% of the time — +17.0% above the average run. Win rate reflects how often runs with the relic end in victory.
What does Red Mask do in Slay the Spire 2?
At the start of each combat, apply Weak to ALL enemies.
How rare is Red Mask in Slay the Spire 2?
Red Mask is a Common relic, picked up in 8.6% of tracked runs.
What is the best card to use with Red Mask?
In tracked runs, Red Mask has performed best alongside Salvo, which lifts its win rate by +64.1% over 3 runs together.
Which class is Red Mask best in?
Red Mask has its highest win rate with The Defect (41.1%).
See Also
Compare Red Mask with the rest of the best Slay the Spire 2 relics, cards, and classes below.