Red Mask Relic

Is Red Mask good in Slay the Spire 2?

Red Mask is a common relic in Slay the Spire 2. While carried, it does the following: At the start of each combat, apply Weak to ALL enemies. It currently underperforms most relics, sitting at D tier in our Slay the Spire 2 relic rankings.

Across 1919 recorded runs, decks carrying it win 36.6% of the time, comfortably clear of the 13.8% average, by 22.7%. It’s a more situational relic, showing up in just 9.2% of runs. The class that gets the most out of it is the Regent, at a 40.8% win rate. Regent players hold onto it in 9.9% of their runs.

It combos especially well with Restlessness, worth a +45.8% win-rate swing together. Another strong card to run with it is Alchemize, worth +39.6% to its win rate. On average it’s acquired around floor 21 of a run. Its common rarity shapes how frequently you’ll run into it.

It has 695 run wins against 1205 losses in our tracked data. When runs carrying it end, the most frequent culprit is Test Subject Boss, which closes out 5.7% of them. Read on for Red Mask’s complete card, class, and threat breakdown before you decide to pick it up.

Pick or Skip: Red Mask

Out of 3091 recorded offers Red Mask is taken 63.2% of the time, and taking it is worth +10.4% in pick lift — 36.9% for runs that picked it against 26.4% for runs that skipped, across 1930 decided runs.

Taken 1953 times out of 3091 offers.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

Best Cards with Red Mask

Ranked by win-rate lift, the best cards to run with Red Mask are Restlessness (+45.8%), Alchemize (+39.6%), and Bundle of Joy (+39.2%).

Restlessness+45.8%18 runsAlchemize+39.6%22 runsBundle of Joy+39.2%33 runsApotheosis+38.4%33 runsSecret Technique+38.4%25 runsBolas+35.6%19 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Red Mask Win Rate by Class

Red Mask shows up across 5 classes, led by Regent (40.8%), Silent (40.8%), and Necrobinder (37.3%) by win rate.

The Regent40.8%326 runsThe Silent40.8%426 runsThe Necrobinder37.3%324 runsThe Ironclad33.0%466 runsThe Defect31.5%367 runs

Red Mask Details

Red Mask is a common relic carried in 9.2% of runs and usually picked up around floor 21.

At the start of each combat, apply Weak to ALL enemies.

What Ends Runs with Red Mask

Red Mask’s most common run-enders are Test Subject Boss (5.7%), Queen Boss (5.6%), and Knowledge Demon Boss (5.4%).

• Test Subject Boss5.7% of runs
• Queen Boss5.6% of runs
• Knowledge Demon Boss5.4% of runs
• Kaiser Crab Boss4.3% of runs
• Aeonglass Boss4.1% of runs

See Also

Compare Red Mask with the rest of the best Slay the Spire 2 relics, cards, and classes below.