
Blood VialRelic
At the start of each combat, heal HP.
Is Blood Vial good in Slay the Spire 2?
In Slay the Spire 2, Blood Vial is a common relic you can pick up on your climb. Its effect: At the start of each combat, heal HP. The data marks it as a weaker relic, settling at D tier — rarely a run-defining grab.
Over 1112 tracked runs the win rate of decks holding it sits at 34.9%, 21.0% ahead of the 13.9% all-run baseline. It sees lighter play, carried in only 9.6% of runs. It does its best work in the hands of the Silent, who post a 41.0% win rate with it. Within Silent runs specifically, it’s carried 9.3% of the time.
Its standout card pairing is Storm of Steel, which lifts the relic’s win rate by +42.5% when both are in play. It also works nicely with Mind Blast, good for a +38.4% win-rate change. It typically enters the deck near floor 22. As a common relic, how often it’s offered depends on its rarity tier.
Of the runs that carried it, 385 ended in victory while 717 fell to a defeat. Its most common run-ender is Test Subject Boss, finishing 6.3% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Blood Vial is worth grabbing.
Blood Vial Win Rate & Pick Rate
At a 34.9% win rate, Blood Vial runs 21.0% ahead of the 13.9% all-run baseline — the bars below put the two side by side.
Run Outcomes with Blood Vial
Across the 1112 runs that carried Blood Vial, 385 ended in a win and 727 in a loss — a 34.6% win share, counting abandons as losses.
- Wins 34.6%
- Losses 65.4%
Pick or Skip: Blood Vial
Players take Blood Vial in 62.4% of the 1809 offers it appears in; those runs win 35.0% against 23.0% for runs that passed, a pick lift of +11.9% over 1118 decided runs.
Taken 1129 times out of 1809 offers.
Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.
Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.
Best Cards with Blood Vial
The cards that gain the most from carrying Blood Vial are Storm of Steel (+42.5%), Mind Blast (+38.4%), and Malaise (+35.6%), each shown with its win-rate swing.
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Blood Vial Win Rate by Class
Of the 5 classes that carry Blood Vial, it performs best with Silent (41.0%), Regent (33.7%), and Necrobinder (32.8%).
Blood Vial Details
Carried in 9.6% of runs, Blood Vial is a common relic typically acquired near floor 22.
At the start of each combat, heal HP.
What Ends Runs with Blood Vial
Runs carrying Blood Vial end most often against Test Subject Boss (6.3%), Knowledge Demon Boss (5.8%), and Queen Boss (4.9%) — the share of its runs each accounts for is shown.
- Test Subject Boss6.3% of runs
- Knowledge Demon Boss5.8% of runs
- Queen Boss4.9% of runs
- Kaiser Crab Boss4.8% of runs
- Aeonglass Boss4.6% of runs
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Blood Vial – Frequently Asked Questions
Is Blood Vial good in Slay the Spire 2?
Across 1112 tracked runs carrying it, Blood Vial wins 34.9% of the time — +21.0% above the average run. Win rate reflects how often runs with the relic end in victory.
What does Blood Vial do in Slay the Spire 2?
At the start of each combat, heal HP.
How rare is Blood Vial in Slay the Spire 2?
Blood Vial is a Common relic, picked up in 9.6% of tracked runs.
What is the best card to use with Blood Vial?
In tracked runs, Blood Vial has performed best alongside Storm of Steel, which lifts its win rate by +42.5% over 32 runs together.
Which class is Blood Vial best in?
Blood Vial has its highest win rate with The Silent (41.0%).
Should I take Blood Vial when it is offered?
Players take Blood Vial in 62.4% of its 1809 recorded offers. Runs that picked it win 35.0% (1118 decided runs) against 23.0% for runs that skipped it (665 decided runs) — a +12.0% difference, and a +11.9% pick lift once sample size is accounted for.
See Also
Keep exploring Slay the Spire 2 tier lists and stats below.