Blood Vial•Relic

Is Blood Vial good in Slay the Spire 2?

In Slay the Spire 2, Blood Vial is a common relic you can pick up on your climb. Its effect: At the start of each combat, heal HP. The data marks it as a weaker relic, settling at D tier — rarely a run-defining grab.

Over 37 tracked runs the win rate of decks holding it sits at 28.6%, 15.9% ahead of the 12.6% all-run baseline. It sees lighter play, carried in only 7.1% of runs. It does its best work in the hands of the Silent, who post a 33.3% win rate with it. Within Silent runs specifically, it’s carried 9.6% of the time.

Its standout card pairing is Mayhem, which lifts the relic’s win rate by +38.1% when both are in play. It also works nicely with Production, good for a +38.1% win-rate change. It typically enters the deck near floor 19. As a common relic, how often it’s offered depends on its rarity tier.

Of the runs that carried it, 10 ended in victory while 25 fell to a defeat. Its most common run-ender is Kaiser Crab Boss, finishing 10.8% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Blood Vial is worth grabbing.

Best Cards with Blood Vial

The cards that gain the most from carrying Blood Vial are Mayhem (+38.1%), Production (+38.1%), and Follow Through (+38.1%), each shown with its win-rate swing.

Mayhem+38.1%3 runsProduction+38.1%3 runsFollow Through+38.1%3 runsFlechettes+38.1%3 runsNoxious Fumes+38.1%3 runsRefine Blade+38.1%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Blood Vial Win Rate by Class

Of the 5 classes that carry Blood Vial, it performs best with Silent (33.3%), Regent (33.3%), and Necrobinder (30.0%).

The Silent33.3%10 runsThe Regent33.3%6 runsThe Necrobinder30.0%11 runsThe Defect20.0%5 runsThe Ironclad20.0%5 runs

Blood Vial Details

Carried in 7.1% of runs, Blood Vial is a common relic typically acquired near floor 19.

At the start of each combat, heal HP.

What Ends Runs with Blood Vial

Runs carrying Blood Vial end most often against Kaiser Crab Boss (10.8%), Decimillipede Elite (8.1%), and Ceremonial Beast Boss (8.1%) — the share of its runs each accounts for is shown.

• Kaiser Crab Boss10.8% of runs
• Decimillipede Elite8.1% of runs
• Ceremonial Beast Boss8.1% of runs
• Queen Boss8.1% of runs
• Vantom Boss5.4% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.