Blood Vial•Relic

Is Blood Vial good in Slay the Spire 2?

In Slay the Spire 2, Blood Vial is a common relic you can pick up on your climb. Its effect: At the start of each combat, heal HP. Performance-wise it’s a steady, unspectacular pick rated C tier overall.

Over 370 tracked runs the win rate of decks holding it sits at 39.9%, 21.0% ahead of the 18.9% all-run baseline. It sees lighter play, carried in only 9.8% of runs. It does its best work in the hands of the Silent, who post a 49.5% win rate with it. Within Silent runs specifically, it’s carried 9.7% of the time.

Its standout card pairing is Beat Down, which lifts the relic’s win rate by +60.1% when both are in play. It also works nicely with Barricade, good for a +60.1% win-rate change. It typically enters the deck near floor 22. As a common relic, how often it’s offered depends on its rarity tier.

Of the runs that carried it, 139 ended in victory while 209 fell to a defeat. Its most common run-ender is Knowledge Demon Boss, finishing 6.5% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Blood Vial is worth grabbing.

Best Cards with Blood Vial

The cards that gain the most from carrying Blood Vial are Beat Down (+60.1%), Barricade (+60.1%), and Seeker Strike (+60.1%), each shown with its win-rate swing.

Beat Down+60.1%3 runsBarricade+60.1%5 runsSeeker Strike+60.1%4 runsDemonic Shield+60.1%3 runsKnife Trap+48.3%18 runsCruelty+46.7%15 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Blood Vial Win Rate by Class

Of the 5 classes that carry Blood Vial, it performs best with Silent (49.5%), Defect (43.3%), and Ironclad (37.8%).

The Silent49.5%95 runsThe Defect43.3%65 runsThe Ironclad37.8%81 runsThe Necrobinder33.8%78 runsThe Regent30.6%51 runs

Blood Vial Details

Carried in 9.8% of runs, Blood Vial is a common relic typically acquired near floor 22.

At the start of each combat, heal HP.

What Ends Runs with Blood Vial

Runs carrying Blood Vial end most often against Knowledge Demon Boss (6.5%), Queen Boss (5.4%), and Test Subject Boss (5.1%) — the share of its runs each accounts for is shown.

• Knowledge Demon Boss6.5% of runs
• Queen Boss5.4% of runs
• Test Subject Boss5.1% of runs
• Kaiser Crab Boss4.6% of runs
• The Insatiable Boss4.1% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.