Anivia - League of Legends Champion
Win Rate
49.7%
Pick Rate
1.9%

Aniviavs Cassiopeia

CMage
Patch26.4
Matches1,089,240
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 5, 2026
MethodologyData Methodology

Anivia vs Cassiopeia is a decisive matchup in LoL patch 26.4. Cassiopeia wins with a 66.7% win rate (+33.3%) over Anivia based on 12 games. Cassiopeia holds the advantage in both the early and late game. Below you'll find the best Anivia build, runes, laning stats, and strategies for the Anivia vs Cassiopeia matchup.

Anivia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Anivia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Cassiopeia - 33.3% win rateCassiopeia(33.3%)
Anivia - 33.3% win rate in this matchup
Anivia
33.3% WR
VS
Cassiopeia vs Anivia matchup - 66.7% win rate
Cassiopeia
66.7% WR

Who Wins the Anivia vs Cassiopeia Matchup?

Cassiopeia wins the Anivia vs Cassiopeia matchup
Winner
Cassiopeia
Matches: 12
33.3%
Win Rate
66.7%
7.1
CS / min
6.0
804
DMG / min
780
11,576
Gold / game
10,728
216
Heal / min
289
746
DMG Mitigated / min
620
1.7
CC / min
1.1
40.0%
Early Game WR
60.0%
28.6%
Late Game WR
71.4%

Anivia vs Cassiopeia Matchup Summary

The Anivia vs Cassiopeia matchup is a decisive matchup in League of Legends ranked play. Based on 12 recent matches analyzed, Cassiopeia wins with a 66.7% win rate compared to Anivia's 33.3%, giving Cassiopeia a 33.3 percentage point advantage. Cassiopeia dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Anivia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Anivia leads by 0.6s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Cassiopeia has a strong advantage in this matchup. Anivia players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Cassiopeia overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Anivia vs Cassiopeia Laning Phase Breakdown

Anivia wins the laning phase against Cassiopeia in League of Legends

Anivia is favored during the laning phase against Cassiopeia, winning 5 out of 5 key stat categories. Anivia holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
7.1Anivia
6.0Cassiopeia
Anivia significantly out-farms Cassiopeia by 1.2 CS per minute, accumulating an estimated 18 CS lead by mid game. This substantial farming gap gives Anivia a major gold advantage and earlier item completions. Cassiopeia players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
804Anivia
780Cassiopeia
Damage output is virtually even between Anivia and Cassiopeia, with only 24 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
11,576Anivia
10,728Cassiopeia
Anivia generates a commanding 848 more gold per game than Cassiopeia. This substantial economic advantage means Anivia consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Cassiopeia should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.7Anivia
1.1Cassiopeia
Anivia provides 0.6 seconds more crowd control per minute than Cassiopeia, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Anivia coordinate with their jungler and control the pace of skirmishes.
Sustain
963Anivia
909Cassiopeia
Anivia heals and mitigates 54 more damage per minute than Cassiopeia, providing moderate extra durability. This sustain edge allows Anivia to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Cassiopeia.

Best Anivia Build Against Cassiopeia

Spellslinger's Shoes is the optimal boots choice against Cassiopeia, providing the mobility and stats Anivia needs most in this matchup. The top-performing core items for Anivia against Cassiopeia are Rod of Ages, Liandry's Torment and Zhonya's Hourglass. This combination gives Anivia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Cassiopeia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Anivia vs Cassiopeia matchup.

Early Game vs Late Game

Early Game
Cassiopeia
60.0%
+20.0% advantage
Anivia early game win rateAnivia40.0%
Cassiopeia early game win rateCassiopeia60.0%
Late Game
Cassiopeia
71.4%
+42.9% advantage
Anivia late game win rateAnivia28.6%
Cassiopeia late game win rateCassiopeia71.4%

Cassiopeia dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Anivia. This lopsided early game means Cassiopeia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Cassiopeia is far superior in the late game (25+ minutes), boasting a 71.4% win rate — 42.9 points above Anivia. Extended games heavily favor Cassiopeia, whose kit and scaling make them a dominant force in team fights and objective control.

Cassiopeia holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Anivia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Anivia Runes Against Cassiopeia

Domination rune tree - Anivia primary runes vs CassiopeiaDomination
Electrocute - best Anivia rune vs CassiopeiaCheap Shot - best Anivia rune vs CassiopeiaGrisly Mementos - best Anivia rune vs CassiopeiaRelentless Hunter - best Anivia rune vs Cassiopeia
Precision rune tree - Anivia secondary runes vs CassiopeiaPrecision
Presence of Mind - best Anivia rune vs CassiopeiaCoup de Grace - best Anivia rune vs Cassiopeia
100.0% WR

The Domination and Precision rune setup gives Anivia the best tools to compete against Cassiopeia in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Anivia matchup data for League of Legends patch 26.4. The table below shows Anivia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Anivia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Anivia matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.39%2126.872911,35850.0%44.9%
46.47%1706.681711,89743.4%48.9%
41.96%1436.872711,75952.5%34.5%
47.41%1164.671011,36142.5%50.7%
47.71%1106.680511,87837.2%54.5%
50.00%1047.068711,36543.1%56.6%
50.50%1026.073411,65553.5%48.3%
62.07%876.786511,87271.8%54.2%
52.38%856.973411,31653.3%51.3%
44.44%836.978311,06948.7%40.5%
51.85%826.575311,53250.0%53.5%
46.67%756.588211,74047.1%46.3%
42.67%756.276311,57831.3%51.2%
52.86%706.371211,25853.3%52.5%
53.97%637.387512,06963.3%45.5%
44.44%636.579611,83534.6%51.4%
39.68%631.65249,15750.0%32.4%
54.10%616.584411,01350.0%60.0%
44.83%596.974712,43543.5%45.7%
61.02%597.182112,56060.7%61.3%
58.49%536.783211,76045.5%67.7%
44.23%534.970411,30847.8%41.4%
57.69%536.768411,46255.6%60.0%
57.69%526.470411,06745.8%67.9%
63.46%526.775111,89165.2%62.1%
50.00%467.091811,85550.0%50.0%
44.19%446.478511,68533.3%52.0%
61.36%446.785812,42264.7%59.3%
46.51%436.781112,46760.0%39.3%
45.24%431.959711,17735.7%50.0%
54.76%422.661610,68362.5%50.0%
45.24%427.085211,67352.4%38.1%
47.62%426.973911,35457.9%39.1%
43.59%392.161710,43530.8%50.0%
57.89%386.979311,20769.6%40.0%
45.71%356.872912,32053.3%40.0%
47.06%342.659910,71660.0%41.7%
65.63%344.384710,77282.3%46.7%
54.55%331.859810,18240.0%66.7%
42.42%333.36609,94953.3%33.3%
53.33%306.584013,38455.6%52.4%
66.67%306.580912,18460.0%70.0%
50.00%305.069910,02856.3%42.9%
62.07%296.278513,33383.3%56.5%
29.63%276.599212,33718.2%37.5%
55.56%276.878412,61772.7%43.8%
53.85%266.892211,37761.5%46.1%
44.00%256.864310,57453.9%33.3%
60.00%256.178212,02575.0%52.9%
48.00%252.15979,76153.9%41.7%
56.00%256.91,01913,29442.9%61.1%
52.00%252.25969,58150.0%53.3%
54.17%242.76858,47147.1%71.4%
50.00%246.11,01312,35744.4%53.3%
52.17%245.692511,88257.1%50.0%
62.50%246.974211,31572.7%53.9%
50.00%241.959710,46557.1%47.1%
70.83%243.458710,14450.0%81.3%
68.18%236.679512,19566.7%69.2%
47.83%236.677811,63361.5%30.0%
52.38%227.482712,21666.7%41.7%
50.00%221.84898,88945.5%54.5%
63.64%222.16059,82350.0%75.0%
50.00%225.070511,62357.1%46.7%
54.55%221.95948,77572.7%36.4%
59.09%221.859110,31471.4%53.3%
45.45%221.95089,98150.0%42.9%
26.32%196.765511,72125.0%27.3%
52.94%176.488212,95744.4%62.5%
75.00%166.679412,43283.3%70.0%
53.33%164.174911,90880.0%40.0%
43.75%165.778611,93250.0%33.3%
37.50%167.07209,81554.5%0.0%
81.25%166.47889,85370.0%100.0%
46.67%155.77259,59050.0%40.0%
46.67%155.56748,96854.5%25.0%
40.00%156.877313,14857.1%25.0%
42.86%146.485212,17880.0%22.2%
35.71%141.65439,7230.0%55.6%
35.71%142.14728,22950.0%16.7%
38.46%136.052710,24833.3%50.0%
38.46%135.483113,811100.0%27.3%
30.77%135.87307,58730.0%33.3%
33.33%127.180411,57640.0%28.6%
25.00%123.46779,80150.0%0.0%
58.33%126.498411,96471.4%40.0%
33.33%121.65229,58342.9%20.0%
45.45%116.779111,7280.0%71.4%
63.64%111.558610,75666.7%62.5%
54.55%115.376410,61628.6%100.0%
63.64%117.786013,18366.7%60.0%
36.36%115.670711,49366.7%25.0%
36.36%116.07149,9750.0%80.0%
36.36%116.370310,54220.0%50.0%
63.64%116.780212,32850.0%71.4%
70.00%102.86199,52833.3%85.7%
50.00%107.272810,47633.3%75.0%
30.00%106.799312,58366.7%14.3%
20.00%106.999711,61625.0%16.7%
70.00%107.069712,15183.3%50.0%
40.00%106.579111,00457.1%0.0%
66.67%107.279210,89583.3%33.3%
37.50%93.859710,19933.3%40.0%
33.33%96.865510,69220.0%50.0%
55.56%96.578113,81533.3%66.7%
44.44%92.368711,15925.0%60.0%
25.00%86.981411,74220.0%33.3%
62.50%82.455610,25260.0%66.7%
14.29%75.373911,1050.0%33.3%
57.14%76.883311,81650.0%66.7%
71.43%71.65268,33875.0%66.7%
66.67%66.781413,15550.0%75.0%
33.33%62.25859,29366.7%0.0%
33.33%64.44827,28940.0%0.0%
66.67%66.81,12014,638100.0%60.0%
66.67%67.176113,3430.0%100.0%
50.00%67.080212,13733.3%66.7%
33.33%67.194612,48850.0%25.0%
66.67%66.087611,03766.7%66.7%
50.00%65.783711,72050.0%50.0%
50.00%56.767411,95350.0%50.0%
80.00%57.373011,290100.0%50.0%
80.00%56.187315,369100.0%75.0%
80.00%56.51,05512,320100.0%66.7%
60.00%57.086613,182100.0%33.3%
60.00%56.36319,13450.0%100.0%
60.00%56.479114,209100.0%33.3%
20.00%57.187712,6340.0%25.0%
20.00%56.81,03815,65650.0%0.0%
40.00%55.986713,92150.0%33.3%
🔍

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Anivia vs Cassiopeia - Frequently Asked Questions

How does Anivia do against Cassiopeia in League of Legends?

Cassiopeia wins the Anivia vs Cassiopeia matchup with a 66.7% win rate compared to Anivia's 33.3%, a 33.3 percentage point difference. This data is based on 12 recent ranked games in patch 26.4.

How does Anivia do against Cassiopeia in the early game?

In the early game, Cassiopeia has the advantage against Anivia with a 60.0% win rate versus 40.0%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Anivia do against Cassiopeia in the late game?

In the late game, Cassiopeia takes over the Anivia vs Cassiopeia matchup with a 71.4% win rate compared to 28.6%. Cassiopeia scales better into team fights and objective contests after 25 minutes.

Who wins the Anivia vs Cassiopeia matchup?

Cassiopeia wins the matchup against Anivia with a 66.7% win rate in League of Legends patch 26.4. The 33.3 percentage point advantage means Cassiopeia is significantly favored in this lane matchup based on 12 games analyzed.

What is the best Anivia build against Cassiopeia?

The best Anivia build against Cassiopeia includes Rod of Ages, Liandry's Torment, Zhonya's Hourglass with Spellslinger's Shoes. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Anivia runes against Cassiopeia?

The best Anivia runes against Cassiopeia use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Anivia vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.

Does Anivia counter Cassiopeia?

No, Anivia struggles against Cassiopeia with only a 33.3% win rate. Cassiopeia has the advantage in this matchup. Anivia players should focus on safe farming and avoiding extended trades to minimize Cassiopeia's lead.

How do I play Anivia against Cassiopeia?

When playing Anivia against Cassiopeia, play cautiously and avoid Cassiopeia's power spikes. Look for jungle assistance and team-dependent plays since Cassiopeia has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.