Anivia - League of Legends Champion
Win Rate
47.1%
Pick Rate
1.4%

Aniviavs Lissandra

FMage
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Anivia vs Lissandra is a decisive matchup in LoL patch 26.14. Anivia wins with a 62.5% win rate (+25.0%) over Lissandra based on 8 games. Anivia holds the advantage in both the early and late game. Below you'll find the best Anivia build, runes, laning stats, and strategies for the Anivia vs Lissandra matchup.

Join Our Discord
Bug reports, feature requests & developer chat
Join Discord
Metabot Logo
MetaBot Desktop
Counter picks in champ select

Anivia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Anivia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Anivia - 62.5% win rate in this matchup
Anivia
62.5% WR
VS
Lissandra vs Anivia matchup - 37.5% win rate
Lissandra
37.5% WR

Who Wins the Anivia vs Lissandra Matchup?

Anivia wins the Anivia vs Lissandra matchup
Winner
Anivia
Matches: 8
62.5%
Win Rate
37.5%
6.3
CS / min
6.4
804
DMG / min
880
10,776
Gold / game
10,160
140
Heal / min
154
570
DMG Mitigated / min
441
1.5
CC / min
1.7
50.0%
Early Game WR
50.0%
66.7%
Late Game WR
33.3%

Anivia vs Lissandra Matchup Summary

The Anivia vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 8 recent matches analyzed, Anivia wins with a 62.5% win rate compared to Lissandra's 37.5%, giving Anivia a 25.0 percentage point advantage. Anivia dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Lissandra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Anivia leads by 115 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Anivia players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Anivia vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Anivia in League of Legends

Lissandra is favored during the laning phase against Anivia, winning 3 out of 5 key stat categories. Lissandra holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
6.3Anivia
6.4Lissandra
Anivia and Lissandra farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
804Anivia
880Lissandra
Lissandra deals 76 more champion damage per minute than Anivia. While noticeable in extended trades, this gap can be offset by Anivia choosing favorable fight windows, such as engaging when Lissandra's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
10,776Anivia
10,160Lissandra
Anivia earns 616 more gold per game than Lissandra, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Anivia slightly faster item completions.
Utility
1.5Anivia
1.7Lissandra
Both Anivia and Lissandra provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
710Anivia
595Lissandra
Anivia heals and mitigates 115 more damage per minute than Lissandra, providing moderate extra durability. This sustain edge allows Anivia to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Lissandra.

Best Anivia Build Against Lissandra

Swiftmarch is the optimal boots choice against Lissandra, providing the mobility and stats Anivia needs most in this matchup. The top-performing core items for Anivia against Lissandra are Rod of Ages, Zhonya's Hourglass and Malignance. This combination gives Anivia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Anivia vs Lissandra matchup.

Early Game vs Late Game

Early Game
Anivia
50.0%
+0.0% advantage
Anivia early game win rateAnivia50.0%
Lissandra early game win rateLissandra50.0%
Late Game
Anivia
66.7%
+33.3% advantage
Anivia late game win rateAnivia66.7%
Lissandra late game win rateLissandra33.3%

The early game (first 15 minutes) is a toss-up between Anivia and Lissandra, with Anivia holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Anivia is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Lissandra. Extended games heavily favor Anivia, whose kit and scaling make them a dominant force in team fights and objective control.

Anivia holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Lissandra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Anivia Runes Against Lissandra

Domination rune tree - Anivia primary runes vs LissandraDomination
Electrocute - best Anivia rune vs LissandraCheap Shot - best Anivia rune vs LissandraGrisly Mementos - best Anivia rune vs LissandraRelentless Hunter - best Anivia rune vs Lissandra
Precision rune tree - Anivia secondary runes vs LissandraPrecision
Coup de Grace - best Anivia rune vs LissandraPresence of Mind - best Anivia rune vs Lissandra
66.7% WR

Running Domination primary with Precision secondary allows Anivia to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.


Anivia matchup data for League of Legends patch 26.14. The table below shows Anivia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Anivia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Anivia matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
35.85%536.37019,61325.9%46.1%
30.43%466.678210,09435.7%22.2%
39.13%465.36599,61836.8%40.7%
44.44%456.386411,52446.7%43.3%
43.18%446.371411,10926.7%51.7%
47.73%446.775310,72127.8%61.5%
35.00%406.574811,35637.5%33.3%
45.16%316.478210,77923.1%61.1%
46.43%286.578711,40645.5%47.1%
35.71%286.769011,16228.6%42.9%
66.67%276.480511,61063.6%68.8%
46.15%266.065310,74950.0%43.8%
36.00%253.05689,15955.6%25.0%
58.33%246.796112,23845.5%69.2%
52.17%236.374511,64916.7%64.7%
50.00%226.57539,98254.5%45.5%
52.38%216.674611,71771.4%42.9%
61.90%215.572710,99842.9%71.4%
45.00%206.382011,52362.5%33.3%
52.63%196.286810,77137.5%63.6%
33.33%186.073510,13127.3%42.9%
72.22%185.967910,89175.0%70.0%
50.00%166.36149,07555.6%42.9%
37.50%166.66289,39275.0%0.0%
56.25%166.781012,39550.0%60.0%
46.67%156.873111,38842.9%50.0%
46.67%152.05529,43850.0%46.1%
40.00%152.25319,09033.3%44.4%
57.14%146.873012,10775.0%50.0%
35.71%146.489711,62250.0%30.0%
38.46%136.675112,04933.3%40.0%
25.00%126.774212,4100.0%30.0%
41.67%126.584811,21925.0%50.0%
50.00%126.887710,31850.0%50.0%
50.00%126.16748,36950.0%50.0%
81.82%116.270710,19171.4%100.0%
36.36%117.062911,57925.0%42.9%
36.36%115.568712,177100.0%30.0%
45.45%116.466710,99366.7%37.5%
63.64%115.475411,56950.0%71.4%
63.64%116.794513,58066.7%62.5%
45.45%113.263011,58250.0%42.9%
60.00%101.94837,77857.1%66.7%
50.00%106.574310,01233.3%75.0%
55.56%97.394811,43840.0%75.0%
44.44%92.04428,07540.0%50.0%
44.44%92.464510,161100.0%28.6%
62.50%87.376711,954100.0%50.0%
37.50%82.959110,60766.7%20.0%
50.00%85.390311,91166.7%40.0%
37.50%84.765410,06625.0%50.0%
50.00%85.362210,48250.0%50.0%
37.50%86.787011,22150.0%25.0%
62.50%86.380410,77650.0%66.7%
87.50%87.078513,172100.0%85.7%
12.50%87.05369,4830.0%20.0%
28.57%74.090614,5310.0%33.3%
71.43%76.573414,565100.0%60.0%
28.57%75.05619,06633.3%25.0%
57.14%72.35289,20150.0%66.7%
28.57%75.97829,98650.0%0.0%
42.86%76.38019,29866.7%25.0%
71.43%73.070514,519100.0%66.7%
57.14%73.876010,8790.0%66.7%
57.14%76.877012,335100.0%40.0%
50.00%66.284614,902100.0%40.0%
50.00%66.871511,66366.7%33.3%
50.00%66.271010,00866.7%33.3%
50.00%66.77168,08475.0%0.0%
50.00%66.45059,88933.3%66.7%
66.67%62.26569,72075.0%50.0%
50.00%66.388414,2980.0%75.0%
50.00%63.25937,55166.7%33.3%
83.33%65.389710,183100.0%75.0%
40.00%56.285610,15666.7%0.0%
80.00%53.768812,2410.0%100.0%
80.00%57.01,00810,688100.0%50.0%
20.00%52.15765,9410.0%100.0%
40.00%56.96789,58050.0%33.3%
40.00%57.65698,50425.0%100.0%
40.00%56.480414,0190.0%40.0%
20.00%56.770110,3090.0%25.0%
80.00%55.05809,580100.0%50.0%
60.00%56.01,00914,552100.0%50.0%
60.00%56.16009,47033.3%100.0%
40.00%56.01,04212,9200.0%40.0%
40.00%57.279313,10150.0%33.3%
40.00%56.452912,6880.0%40.0%
60.00%56.559010,06166.7%50.0%
40.00%55.38889,6630.0%66.7%
20.00%55.168311,60033.3%0.0%

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Anivia vs Lissandra - Frequently Asked Questions

How does Anivia do against Lissandra in League of Legends?

Anivia wins the Anivia vs Lissandra matchup with a 62.5% win rate compared to Lissandra's 37.5%, a 25.0 percentage point difference. This data is based on 8 recent ranked games in patch 26.14.

How does Anivia do against Lissandra in the early game?

In the early game, Anivia has the advantage against Lissandra with a 50.0% win rate versus 50.0%. Anivia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Anivia do against Lissandra in the late game?

In the late game, Anivia takes over the Anivia vs Lissandra matchup with a 66.7% win rate compared to 33.3%. Anivia scales better into team fights and objective contests after 25 minutes.

Who wins the Anivia vs Lissandra matchup?

Anivia wins the matchup against Lissandra with a 62.5% win rate in League of Legends patch 26.14. The 25.0 percentage point advantage means Anivia is significantly favored in this lane matchup based on 8 games analyzed.

What is the best Anivia build against Lissandra?

The best Anivia build against Lissandra includes Rod of Ages, Zhonya's Hourglass, Malignance with Swiftmarch. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Anivia runes against Lissandra?

The best Anivia runes against Lissandra use the Domination primary tree with Precision secondary. This rune setup achieves a 66.7% win rate in the Anivia vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Anivia counter Lissandra?

Yes, Anivia has a favorable matchup against Lissandra with a 62.5% win rate. Anivia strongly counters Lissandra in lane based on current patch 26.14 data.

How do I play Anivia against Lissandra?

When playing Anivia against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.