
Aniviavs Lissandra
Anivia vs Lissandra is a decisive matchup in LoL patch 26.7. Lissandra wins with a 58.6% win rate (+17.2%) over Anivia based on 29 games. Lissandra holds the advantage in both the early and late game. Below you'll find the best Anivia build, runes, laning stats, and strategies for the Anivia vs Lissandra matchup.
Anivia Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Anivia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Anivia vs Lissandra Matchup?

Anivia vs Lissandra Matchup Summary
The Anivia vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 29 recent matches analyzed, Lissandra wins with a 58.6% win rate compared to Anivia's 41.4%, giving Lissandra a 17.2 percentage point advantage. Lissandra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Anivia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Anivia leads by 131 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra has a strong advantage in this matchup. Anivia players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Lissandra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Anivia vs Lissandra Laning Phase Breakdown
Anivia is favored during the laning phase against Lissandra, winning 4 out of 5 key stat categories. Anivia holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.
Best Anivia Build Against Lissandra
Mercury's Treads is the optimal boots choice against Lissandra, providing the mobility and stats Anivia needs most in this matchup. The top-performing core items for Anivia against Lissandra are Rod of Ages, Liandry's Torment and Malignance. This combination gives Anivia an effective balance of damage, survivability, and utility for the matchup. This build has a 25.0% win rate across 4 games. While the overall matchup may be difficult, this item path gives Anivia the best chance to compete against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Anivia vs Lissandra matchup.
Early Game vs Late Game
Lissandra dominates the early game (first 15 minutes) with a commanding 63.6% win rate — a 27.3 percentage point lead over Anivia. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Lissandra is far superior in the late game (25+ minutes), boasting a 55.6% win rate — 11.1 points above Anivia. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.
Lissandra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Anivia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Anivia Runes Against Lissandra
The Domination and Sorcery rune setup gives Anivia the best tools to compete against Lissandra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Anivia matchup data for League of Legends patch 26.7. The table below shows Anivia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Anivia build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 43.37% | 83 | 6.6 | 746 | 12,018 | 48.6% | 39.1% | |
| 38.36% | 73 | 6.7 | 750 | 11,258 | 38.7% | 38.1% | |
| 41.94% | 62 | 6.6 | 688 | 11,239 | 41.9% | 41.9% | |
| 37.74% | 53 | 6.3 | 808 | 11,340 | 37.0% | 38.5% | |
| 50.00% | 52 | 4.3 | 657 | 10,286 | 50.0% | 50.0% | |
| 44.23% | 52 | 6.6 | 798 | 10,755 | 48.1% | 40.0% | |
| 55.77% | 52 | 5.9 | 756 | 12,174 | 66.7% | 48.4% | |
| 47.83% | 46 | 6.6 | 844 | 11,232 | 52.2% | 43.5% | |
| 48.89% | 45 | 6.5 | 752 | 11,206 | 45.0% | 52.0% | |
| 54.55% | 44 | 6.2 | 671 | 11,139 | 60.9% | 47.6% | |
| 59.52% | 42 | 6.8 | 734 | 10,497 | 73.1% | 37.5% | |
| 50.00% | 40 | 6.8 | 694 | 10,262 | 42.9% | 57.9% | |
| 44.74% | 38 | 6.5 | 704 | 10,539 | 50.0% | 37.5% | |
| 31.43% | 35 | 6.8 | 782 | 12,634 | 33.3% | 30.4% | |
| 35.48% | 31 | 6.3 | 831 | 12,711 | 42.9% | 29.4% | |
| 48.39% | 31 | 6.8 | 703 | 12,669 | 40.0% | 56.3% | |
| 38.71% | 31 | 1.8 | 538 | 10,155 | 45.5% | 35.0% | |
| 54.84% | 31 | 4.8 | 833 | 11,996 | 50.0% | 57.1% | |
| 60.00% | 30 | 6.2 | 713 | 11,459 | 45.5% | 68.4% | |
| 53.33% | 30 | 6.9 | 753 | 11,397 | 62.5% | 42.9% | |
| 41.38% | 29 | 6.6 | 828 | 11,876 | 36.4% | 44.4% | |
| 50.00% | 28 | 6.7 | 731 | 11,813 | 58.3% | 43.8% | |
| 44.44% | 27 | 6.6 | 658 | 10,347 | 43.8% | 45.5% | |
| 44.44% | 27 | 4.8 | 678 | 10,340 | 38.5% | 50.0% | |
| 53.85% | 26 | 6.7 | 803 | 10,965 | 30.8% | 76.9% | |
| 62.50% | 24 | 6.8 | 846 | 11,820 | 76.9% | 45.5% | |
| 54.17% | 24 | 5.2 | 744 | 12,215 | 57.1% | 52.9% | |
| 45.83% | 24 | 6.4 | 713 | 11,901 | 44.4% | 46.7% | |
| 47.83% | 23 | 1.9 | 540 | 9,037 | 50.0% | 45.5% | |
| 56.52% | 23 | 6.3 | 754 | 12,081 | 70.0% | 46.1% | |
| 69.57% | 23 | 6.8 | 757 | 11,043 | 71.4% | 66.7% | |
| 50.00% | 22 | 6.0 | 673 | 11,805 | 25.0% | 64.3% | |
| 59.09% | 22 | 6.8 | 736 | 11,468 | 53.9% | 66.7% | |
| 47.62% | 21 | 1.9 | 541 | 9,216 | 33.3% | 58.3% | |
| 60.00% | 20 | 6.9 | 783 | 12,318 | 60.0% | 60.0% | |
| 45.00% | 20 | 1.9 | 484 | 9,494 | 40.0% | 50.0% | |
| 45.00% | 20 | 6.2 | 800 | 10,898 | 33.3% | 54.5% | |
| 36.84% | 19 | 1.9 | 559 | 7,752 | 46.1% | 16.7% | |
| 52.63% | 19 | 3.6 | 645 | 10,675 | 75.0% | 36.4% | |
| 31.58% | 19 | 2.8 | 544 | 8,374 | 28.6% | 40.0% | |
| 21.05% | 19 | 1.8 | 562 | 9,760 | 25.0% | 18.2% | |
| 57.89% | 19 | 6.7 | 874 | 11,130 | 55.6% | 60.0% | |
| 68.42% | 19 | 6.6 | 788 | 12,014 | 71.4% | 66.7% | |
| 33.33% | 18 | 7.1 | 839 | 12,361 | 50.0% | 25.0% | |
| 55.56% | 18 | 3.6 | 646 | 11,349 | 33.3% | 66.7% | |
| 35.29% | 17 | 2.4 | 633 | 10,039 | 22.2% | 50.0% | |
| 41.18% | 17 | 7.0 | 696 | 11,071 | 40.0% | 42.9% | |
| 35.29% | 17 | 6.5 | 714 | 11,484 | 28.6% | 40.0% | |
| 31.25% | 16 | 3.1 | 856 | 10,569 | 33.3% | 30.0% | |
| 50.00% | 16 | 2.7 | 533 | 9,912 | 40.0% | 54.5% | |
| 50.00% | 16 | 3.5 | 574 | 9,075 | 12.5% | 87.5% | |
| 60.00% | 15 | 1.9 | 602 | 10,527 | 33.3% | 77.8% | |
| 46.67% | 15 | 5.3 | 672 | 13,053 | 60.0% | 40.0% | |
| 42.86% | 14 | 1.7 | 532 | 8,246 | 40.0% | 50.0% | |
| 57.14% | 14 | 1.7 | 457 | 8,919 | 50.0% | 62.5% | |
| 64.29% | 14 | 1.7 | 526 | 9,397 | 66.7% | 62.5% | |
| 38.46% | 13 | 6.5 | 832 | 12,108 | 16.7% | 57.1% | |
| 61.54% | 13 | 6.8 | 792 | 13,003 | 66.7% | 57.1% | |
| 61.54% | 13 | 6.3 | 717 | 10,468 | 62.5% | 60.0% | |
| 69.23% | 13 | 6.8 | 856 | 12,702 | 83.3% | 57.1% | |
| 76.92% | 13 | 7.2 | 798 | 12,363 | 100.0% | 50.0% | |
| 41.67% | 12 | 5.7 | 924 | 12,479 | 50.0% | 37.5% | |
| 41.67% | 12 | 1.9 | 485 | 8,552 | 37.5% | 50.0% | |
| 83.33% | 12 | 7.3 | 1,159 | 12,878 | 80.0% | 85.7% | |
| 58.33% | 12 | 5.5 | 682 | 12,224 | 40.0% | 71.4% | |
| 63.64% | 11 | 6.8 | 907 | 10,273 | 80.0% | 50.0% | |
| 63.64% | 11 | 6.0 | 1,062 | 10,876 | 80.0% | 50.0% | |
| 27.27% | 11 | 1.5 | 552 | 8,627 | 25.0% | 33.3% | |
| 36.36% | 11 | 4.9 | 919 | 14,958 | 25.0% | 42.9% | |
| 45.45% | 11 | 6.4 | 927 | 11,564 | 50.0% | 40.0% | |
| 27.27% | 11 | 1.7 | 608 | 10,169 | 50.0% | 22.2% | |
| 40.00% | 10 | 6.4 | 908 | 12,216 | 40.0% | 40.0% | |
| 60.00% | 10 | 7.6 | 772 | 12,322 | 75.0% | 50.0% | |
| 70.00% | 10 | 6.3 | 853 | 11,393 | 60.0% | 80.0% | |
| 77.78% | 9 | 6.8 | 1,039 | 13,830 | 100.0% | 75.0% | |
| 22.22% | 9 | 2.8 | 461 | 8,784 | 0.0% | 40.0% | |
| 44.44% | 9 | 6.9 | 782 | 11,811 | 50.0% | 42.9% | |
| 44.44% | 9 | 2.9 | 573 | 12,338 | 0.0% | 50.0% | |
| 22.22% | 9 | 6.3 | 669 | 11,090 | 0.0% | 33.3% | |
| 44.44% | 9 | 6.3 | 878 | 12,553 | 50.0% | 40.0% | |
| 55.56% | 9 | 1.6 | 611 | 11,010 | 66.7% | 50.0% | |
| 62.50% | 8 | 6.7 | 649 | 12,597 | 100.0% | 57.1% | |
| 50.00% | 8 | 2.5 | 668 | 10,737 | 100.0% | 42.9% | |
| 62.50% | 8 | 6.7 | 785 | 11,946 | 33.3% | 80.0% | |
| 37.50% | 8 | 7.4 | 771 | 11,916 | 66.7% | 20.0% | |
| 87.50% | 8 | 7.6 | 1,015 | 13,365 | 100.0% | 75.0% | |
| 57.14% | 7 | 7.0 | 654 | 9,675 | 40.0% | 100.0% | |
| 71.43% | 7 | 7.9 | 973 | 12,833 | 80.0% | 50.0% | |
| 71.43% | 7 | 6.4 | 694 | 10,663 | 75.0% | 66.7% | |
| 42.86% | 7 | 7.0 | 658 | 9,614 | 60.0% | 0.0% | |
| 14.29% | 7 | 7.1 | 854 | 11,617 | 0.0% | 25.0% | |
| 50.00% | 6 | 6.0 | 815 | 7,923 | 50.0% | 50.0% | |
| 66.67% | 6 | 7.0 | 792 | 14,190 | 100.0% | 60.0% | |
| 83.33% | 6 | 6.2 | 951 | 12,293 | 100.0% | 75.0% | |
| 50.00% | 6 | 6.2 | 595 | 9,450 | 50.0% | 50.0% | |
| 50.00% | 6 | 3.5 | 752 | 12,741 | 0.0% | 50.0% | |
| 66.67% | 6 | 6.1 | 525 | 11,398 | 50.0% | 75.0% | |
| 16.67% | 6 | 1.9 | 441 | 9,182 | 0.0% | 25.0% | |
| 40.00% | 5 | 7.2 | 778 | 11,387 | 33.3% | 50.0% | |
| 80.00% | 5 | 7.2 | 668 | 11,841 | 100.0% | 66.7% | |
| 20.00% | 5 | 1.6 | 697 | 8,618 | 20.0% | 0.0% | |
| 60.00% | 5 | 6.9 | 985 | 13,775 | 0.0% | 75.0% | |
| 20.00% | 5 | 3.1 | 507 | 9,383 | 0.0% | 33.3% | |
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Anivia vs Lissandra - Frequently Asked Questions
How does Anivia do against Lissandra in League of Legends?
Lissandra wins the Anivia vs Lissandra matchup with a 58.6% win rate compared to Anivia's 41.4%, a 17.2 percentage point difference. This data is based on 29 recent ranked games in patch 26.7.
How does Anivia do against Lissandra in the early game?
In the early game, Lissandra has the advantage against Anivia with a 63.6% win rate versus 36.4%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Anivia do against Lissandra in the late game?
In the late game, Lissandra takes over the Anivia vs Lissandra matchup with a 55.6% win rate compared to 44.4%. Lissandra scales better into team fights and objective contests after 25 minutes.
Who wins the Anivia vs Lissandra matchup?
Lissandra wins the matchup against Anivia with a 58.6% win rate in League of Legends patch 26.7. The 17.2 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 29 games analyzed.
What is the best Anivia build against Lissandra?
The best Anivia build against Lissandra includes Rod of Ages, Liandry's Torment, Malignance with Mercury's Treads. This build achieves a 25.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Anivia runes against Lissandra?
The best Anivia runes against Lissandra use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Anivia vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.
Does Anivia counter Lissandra?
No, Anivia struggles against Lissandra with only a 41.4% win rate. Lissandra has the advantage in this matchup. Anivia players should focus on safe farming and avoiding extended trades to minimize Lissandra's lead.
How do I play Anivia against Lissandra?
When playing Anivia against Lissandra, play cautiously and avoid Lissandra's power spikes. Look for jungle assistance and team-dependent plays since Lissandra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.