Lissandra - League of Legends Champion
Win Rate
51.6%
Pick Rate
1.7%

Lissandravs Anivia

SMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 6, 2026
MethodologyData Methodology

Lissandra vs Anivia is a decisive matchup in LoL patch 26.11. Lissandra wins with a 53.6% win rate (+7.1%) over Anivia based on 28 games. Anivia wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Anivia matchup.

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Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 53.6% win rate in this matchup
Lissandra
53.6% WR
VS
Anivia vs Lissandra matchup - 46.4% win rate
Anivia
46.4% WR

Who Wins the Lissandra vs Anivia Matchup?

Lissandra wins the Lissandra vs Anivia matchup
Winner
Lissandra
Matches: 28
53.6%
Win Rate
46.4%
6.7
CS / min
6.6
858
DMG / min
767
11,891
Gold / game
12,350
141
Heal / min
189
447
DMG Mitigated / min
633
1.7
CC / min
1.6
33.3%
Early Game WR
66.7%
63.2%
Late Game WR
36.8%

Lissandra vs Anivia Matchup Summary

The Lissandra vs Anivia matchup is a decisive matchup in League of Legends ranked play. Based on 28 recent matches analyzed, Lissandra wins with a 53.6% win rate compared to Anivia's 46.4%, giving Lissandra a 7.1 percentage point advantage. Game phase dynamics play a critical role here: Anivia controls the early laning stage, but Lissandra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Anivia needs to press advantages before Lissandra reaches their power spikes, while Lissandra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Anivia leads by 234 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Anivia and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Anivia away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Anivia Laning Phase Breakdown

Lissandra wins the laning phase against Anivia in League of Legends

Lissandra is favored during the laning phase against Anivia, winning 3 out of 5 key stat categories. Lissandra holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
6.7Lissandra
6.6Anivia
Lissandra and Anivia farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
858Lissandra
767Anivia
Lissandra heavily out-damages Anivia by 91 DMG/min, dominating both short trades and all-in fights. Anivia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Lissandra's sustained damage advantage take over.
Economy
11,891Lissandra
12,350Anivia
Anivia earns 458 more gold per game than Lissandra, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Anivia slightly faster item completions.
Utility
1.7Lissandra
1.6Anivia
Both Lissandra and Anivia provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
588Lissandra
823Anivia
Anivia vastly out-sustains Lissandra, healing and mitigating 234 more damage per minute. This massive durability gap means Anivia can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lissandra Build Against Anivia

Spellslinger's Shoes is the optimal boots choice against Anivia, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Anivia are Shadowflame, Zhonya's Hourglass and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 80.0% win rate across 10 games — well above average and making it the top item path against Anivia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Anivia matchup.

Early Game vs Late Game

Early Game
Anivia
66.7%
+33.3% advantage
Lissandra early game win rateLissandra33.3%
Anivia early game win rateAnivia66.7%
Late Game
Lissandra
63.2%
+26.3% advantage
Lissandra late game win rateLissandra63.2%
Anivia late game win rateAnivia36.8%

Anivia dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Lissandra. This lopsided early game means Anivia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lissandra is far superior in the late game (25+ minutes), boasting a 63.2% win rate — 26.3 points above Anivia. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Anivia must aggressively press their early advantage and close out the game before Lissandra reaches their scaling breakpoints. If Lissandra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Lissandra Runes Against Anivia

Sorcery rune tree - Lissandra primary runes vs AniviaSorcery
Arcane Comet - best Lissandra rune vs AniviaManaflow Band - best Lissandra rune vs AniviaTranscendence - best Lissandra rune vs AniviaScorch - best Lissandra rune vs Anivia
Domination rune tree - Lissandra secondary runes vs AniviaDomination
Cheap Shot - best Lissandra rune vs AniviaUltimate Hunter - best Lissandra rune vs Anivia
71.4% WR

Running Sorcery primary with Domination secondary allows Lissandra to press their advantage against Anivia, amplifying the strengths that make this a favorable matchup.


Lissandra matchup data for League of Legends patch 26.11. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
58.02%1316.885811,86355.0%60.6%
61.60%1256.791812,36268.6%56.8%
54.47%1236.988112,08353.1%55.4%
54.95%1116.874811,41055.8%54.2%
51.52%996.684011,78453.5%50.0%
50.00%986.985712,17845.0%53.5%
55.56%816.992811,72160.5%51.2%
44.74%766.878111,74844.1%45.2%
57.53%736.785911,06161.5%52.9%
52.86%706.487411,10854.3%51.4%
48.53%687.090811,10755.0%39.3%
53.73%676.178010,94653.1%54.3%
48.28%586.778112,35453.9%43.8%
41.07%566.774210,62436.7%46.1%
58.93%566.573210,32060.6%56.5%
53.70%546.488811,71551.9%55.6%
52.08%486.888112,08468.2%38.5%
55.32%476.384311,46055.6%55.2%
51.16%436.883412,58750.0%51.9%
43.59%396.482510,76435.0%52.6%
46.15%396.577310,88341.2%50.0%
39.47%386.680212,13937.5%40.9%
56.76%376.374210,61842.1%72.2%
56.76%376.878712,41658.8%55.0%
56.76%376.880811,53576.9%45.8%
32.43%377.080410,61129.4%35.0%
48.65%377.083812,68066.7%40.0%
33.33%336.992311,15131.3%35.3%
66.67%306.784412,08075.0%61.1%
65.52%296.986511,46770.6%58.3%
53.57%286.785811,89133.3%63.2%
61.54%267.193811,18175.0%40.0%
37.50%246.470111,94744.4%33.3%
58.33%247.382212,59060.0%57.1%
50.00%227.076411,84454.5%45.5%
54.55%226.61,01413,02066.7%50.0%
31.82%226.768410,84522.2%38.5%
33.33%216.874611,90044.4%25.0%
57.14%215.782310,46554.5%60.0%
73.68%196.980510,70775.0%72.7%
57.89%196.985412,58375.0%45.5%
61.11%187.488713,06550.0%70.0%
38.89%187.294812,87866.7%25.0%
58.82%176.51,06612,41342.9%70.0%
62.50%166.268611,07572.7%40.0%
56.25%166.892312,01450.0%57.1%
66.67%156.984213,080100.0%54.5%
64.29%146.190813,43275.0%60.0%
50.00%144.254910,94350.0%50.0%
64.29%146.779211,67883.3%50.0%
57.14%147.01,08911,13070.0%25.0%
53.85%136.693411,37550.0%57.1%
58.33%127.51,05412,44966.7%50.0%
63.64%116.090612,08133.3%100.0%
45.45%115.590412,09425.0%57.1%
63.64%112.682511,48750.0%71.4%
30.00%105.47418,70242.9%0.0%
70.00%107.194411,75183.3%50.0%
70.00%106.21,13613,233100.0%50.0%
50.00%106.889914,6330.0%62.5%
70.00%106.481112,0790.0%87.5%
55.56%96.281411,09650.0%66.7%
33.33%96.885511,75450.0%20.0%
66.67%96.578212,16033.3%83.3%
22.22%92.55189,7830.0%40.0%
85.71%77.71,15311,498100.0%66.7%
71.43%76.482813,449100.0%66.7%
57.14%77.384211,22350.0%66.7%
100.00%78.28329,161100.0%100.0%
57.14%72.986810,35560.0%50.0%
42.86%77.48559,99550.0%33.3%
57.14%77.080513,44150.0%66.7%
50.00%66.469210,47333.3%66.7%
33.33%66.78659,25050.0%0.0%
50.00%65.784212,7490.0%50.0%
80.00%56.88199,894100.0%66.7%
60.00%57.671711,88250.0%66.7%
60.00%57.593814,8270.0%75.0%
40.00%52.155411,1230.0%40.0%
60.00%56.576611,909100.0%50.0%
40.00%56.95498,21433.3%50.0%
80.00%53.669512,683100.0%50.0%
60.00%52.24318,35366.7%50.0%
60.00%57.51,17014,036100.0%33.3%
40.00%55.596514,4230.0%40.0%
80.00%57.31,24116,644100.0%75.0%
80.00%56.388712,12650.0%100.0%
60.00%56.074710,44750.0%100.0%
20.00%56.67479,3500.0%33.3%

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Lissandra vs Anivia - Frequently Asked Questions

How does Lissandra do against Anivia in League of Legends?

Lissandra wins the Lissandra vs Anivia matchup with a 53.6% win rate compared to Anivia's 46.4%, a 7.1 percentage point difference. This data is based on 28 recent ranked games in patch 26.11.

How does Lissandra do against Anivia in the early game?

In the early game, Anivia has the advantage against Lissandra with a 66.7% win rate versus 33.3%. Anivia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Anivia in the late game?

In the late game, Lissandra takes over the Lissandra vs Anivia matchup with a 63.2% win rate compared to 36.8%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Anivia matchup?

Lissandra wins the matchup against Anivia with a 53.6% win rate in League of Legends patch 26.11. The 7.1 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 28 games analyzed.

What is the best Lissandra build against Anivia?

The best Lissandra build against Anivia includes Shadowflame, Zhonya's Hourglass, Malignance with Spellslinger's Shoes. This build achieves a 80.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Anivia?

The best Lissandra runes against Anivia use the Sorcery primary tree with Domination secondary. This rune setup achieves a 71.4% win rate in the Lissandra vs Anivia matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Anivia?

Yes, Lissandra has a favorable matchup against Anivia with a 53.6% win rate. Lissandra strongly counters Anivia in lane based on current patch 26.11 data.

How do I play Lissandra against Anivia?

When playing Lissandra against Anivia, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Anivia. Build the recommended items and runes for this specific matchup for the best results.