Lissandra - League of Legends Champion
Win Rate
51.3%
Pick Rate
2.2%

Lissandravs Anivia

AMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 19, 2026
MethodologyData Methodology

Lissandra vs Anivia is a decisive matchup in LoL patch 26.7. Lissandra wins with a 58.6% win rate (+17.2%) over Anivia based on 29 games. Lissandra holds the advantage in both the early and late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Anivia matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Anivia - 58.6% win rateAnivia(58.6%)
Lissandra - 58.6% win rate in this matchup
Lissandra
58.6% WR
VS
Anivia vs Lissandra matchup - 41.4% win rate
Anivia
41.4% WR

Who Wins the Lissandra vs Anivia Matchup?

Lissandra wins the Lissandra vs Anivia matchup
Winner
Lissandra
Matches: 29
58.6%
Win Rate
41.4%
6.5
CS / min
6.6
962
DMG / min
828
11,727
Gold / game
11,876
163
Heal / min
181
439
DMG Mitigated / min
551
1.6
CC / min
1.7
63.6%
Early Game WR
36.4%
55.6%
Late Game WR
44.4%

Lissandra vs Anivia Matchup Summary

The Lissandra vs Anivia matchup is a decisive matchup in League of Legends ranked play. Based on 29 recent matches analyzed, Lissandra wins with a 58.6% win rate compared to Anivia's 41.4%, giving Lissandra a 17.2 percentage point advantage. Lissandra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Anivia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Anivia leads by 131 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Anivia and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Anivia away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Anivia Laning Phase Breakdown

Anivia wins the laning phase against Lissandra in League of Legends

Anivia is favored during the laning phase against Lissandra, winning 4 out of 5 key stat categories. Anivia holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.5Lissandra
6.6Anivia
Lissandra and Anivia farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
962Lissandra
828Anivia
Lissandra heavily out-damages Anivia by 134 DMG/min, dominating both short trades and all-in fights. Anivia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Lissandra's sustained damage advantage take over.
Economy
11,727Lissandra
11,876Anivia
Lissandra and Anivia generate nearly equal gold per game, with just a 149 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.6Lissandra
1.7Anivia
Both Lissandra and Anivia provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
601Lissandra
732Anivia
Anivia heals and mitigates 131 more damage per minute than Lissandra, providing moderate extra durability. This sustain edge allows Anivia to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Lissandra.

Best Lissandra Build Against Anivia

Spellslinger's Shoes is the optimal boots choice against Anivia, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Anivia are Shadowflame, Zhonya's Hourglass and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 60.0% win rate across 5 games — well above average and making it the top item path against Anivia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Anivia matchup.

Early Game vs Late Game

Early Game
Lissandra
63.6%
+27.3% advantage
Lissandra early game win rateLissandra63.6%
Anivia early game win rateAnivia36.4%
Late Game
Lissandra
55.6%
+11.1% advantage
Lissandra late game win rateLissandra55.6%
Anivia late game win rateAnivia44.4%

Lissandra dominates the early game (first 15 minutes) with a commanding 63.6% win rate — a 27.3 percentage point lead over Anivia. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Lissandra is far superior in the late game (25+ minutes), boasting a 55.6% win rate — 11.1 points above Anivia. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

Lissandra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Anivia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Lissandra Runes Against Anivia

Domination rune tree - Lissandra primary runes vs AniviaDomination
Electrocute - best Lissandra rune vs AniviaCheap Shot - best Lissandra rune vs AniviaGrisly Mementos - best Lissandra rune vs AniviaUltimate Hunter - best Lissandra rune vs Anivia
Sorcery rune tree - Lissandra secondary runes vs AniviaSorcery
Manaflow Band - best Lissandra rune vs AniviaTranscendence - best Lissandra rune vs Anivia
50.0% WR

Running Domination primary with Sorcery secondary allows Lissandra to press their advantage against Anivia, amplifying the strengths that make this a favorable matchup.


Lissandra matchup data for League of Legends patch 26.7. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
60.00%1306.883712,37853.6%64.9%
57.52%1136.882011,83565.2%52.2%
50.00%766.890711,85747.2%52.5%
45.95%746.778211,93537.5%52.4%
47.95%736.982512,39648.3%47.7%
52.11%717.081212,61135.7%62.8%
53.62%696.788911,32658.1%50.0%
54.55%666.798912,99555.2%54.0%
50.00%626.990112,04736.7%62.5%
54.10%616.687711,06545.5%64.3%
57.38%616.276711,40053.6%60.6%
34.48%586.766810,83031.4%39.1%
40.00%556.372811,33333.3%45.2%
46.94%496.975711,65340.0%51.7%
50.00%486.776511,97850.0%50.0%
50.00%406.476411,31941.2%56.5%
65.00%407.283311,56863.6%66.7%
56.41%397.084511,79244.4%66.7%
60.00%356.876110,99150.0%70.6%
48.57%356.881511,55440.0%55.0%
36.36%336.784111,39846.7%27.8%
21.21%336.478711,43923.1%20.0%
63.33%307.380811,58476.5%46.1%
62.07%297.188313,06883.3%47.1%
58.62%296.596211,72763.6%55.6%
53.57%286.983410,91262.5%41.7%
46.43%286.68679,78147.1%45.5%
53.57%286.881411,53950.0%56.3%
59.26%277.079712,15157.1%61.5%
69.23%266.586913,22971.4%68.4%
57.69%266.679612,06775.0%42.9%
40.00%257.276711,82854.5%28.6%
64.00%256.680511,12450.0%73.3%
41.67%246.992712,63340.0%42.9%
66.67%247.178811,24454.5%76.9%
73.68%197.196712,77550.0%90.9%
44.44%187.31,06512,47460.0%25.0%
64.71%177.290311,48980.0%42.9%
33.33%156.473710,70622.2%50.0%
57.14%146.289412,26342.9%71.4%
42.86%147.375110,43150.0%25.0%
76.92%136.783113,11175.0%77.8%
38.46%136.082212,47860.0%25.0%
30.77%136.896711,40720.0%37.5%
15.38%136.584811,09216.7%14.3%
45.45%116.480812,11440.0%50.0%
27.27%116.792811,21620.0%33.3%
54.55%116.888611,95450.0%57.1%
40.00%106.882512,83166.7%28.6%
50.00%106.452910,44128.6%100.0%
55.56%96.295114,28150.0%57.1%
88.89%97.280612,70675.0%100.0%
55.56%97.288211,46775.0%40.0%
55.56%95.672312,03950.0%60.0%
55.56%97.786112,78766.7%50.0%
75.00%87.487510,71080.0%66.7%
57.14%77.387510,78575.0%33.3%
42.86%75.873510,32566.7%25.0%
85.71%77.087111,26283.3%100.0%
71.43%76.173511,33280.0%50.0%
50.00%61.761410,6240.0%60.0%
83.33%67.91,14313,99850.0%100.0%
33.33%67.796512,2420.0%66.7%
33.33%66.686711,32825.0%50.0%
50.00%62.45439,94466.7%33.3%
83.33%67.183312,020100.0%80.0%
16.67%67.26078,27816.7%0.0%
60.00%56.01,16411,19766.7%50.0%
40.00%53.07276,78640.0%0.0%
20.00%57.793410,62525.0%0.0%
20.00%55.05978,21425.0%0.0%
40.00%53.45178,76125.0%100.0%
80.00%55.064712,91850.0%100.0%
40.00%56.783411,7270.0%66.7%
60.00%56.077611,837100.0%33.3%
40.00%56.374111,1560.0%50.0%
60.00%56.897912,10050.0%66.7%
80.00%56.51,08510,600100.0%66.7%

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Lissandra vs Anivia - Frequently Asked Questions

How does Lissandra do against Anivia in League of Legends?

Lissandra wins the Lissandra vs Anivia matchup with a 58.6% win rate compared to Anivia's 41.4%, a 17.2 percentage point difference. This data is based on 29 recent ranked games in patch 26.7.

How does Lissandra do against Anivia in the early game?

In the early game, Lissandra has the advantage against Anivia with a 63.6% win rate versus 36.4%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Anivia in the late game?

In the late game, Lissandra takes over the Lissandra vs Anivia matchup with a 55.6% win rate compared to 44.4%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Anivia matchup?

Lissandra wins the matchup against Anivia with a 58.6% win rate in League of Legends patch 26.7. The 17.2 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 29 games analyzed.

What is the best Lissandra build against Anivia?

The best Lissandra build against Anivia includes Shadowflame, Zhonya's Hourglass, Malignance with Spellslinger's Shoes. This build achieves a 60.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Anivia?

The best Lissandra runes against Anivia use the Domination primary tree with Sorcery secondary. This rune setup achieves a 50.0% win rate in the Lissandra vs Anivia matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Anivia?

Yes, Lissandra has a favorable matchup against Anivia with a 58.6% win rate. Lissandra strongly counters Anivia in lane based on current patch 26.7 data.

How do I play Lissandra against Anivia?

When playing Lissandra against Anivia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.