Nautilus - League of Legends Champion
Win Rate
49.2%
Pick Rate
5.0%

Nautilusvs Annie

DTankSupport
Patch26.12
Matches328,930
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 24, 2026
MethodologyData Methodology

Nautilus vs Annie is a decisive matchup in LoL patch 26.12. Nautilus wins with a 66.7% win rate (+33.3%) over Annie based on 6 games. Nautilus holds the advantage in both the early and late game. Below you'll find the best Nautilus build, runes, laning stats, and strategies for the Nautilus vs Annie matchup.

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Nautilus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Nautilus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Nautilus - 66.7% win rate in this matchup
Nautilus
66.7% WR
VS
Annie vs Nautilus matchup - 33.3% win rate
Annie
33.3% WR

Who Wins the Nautilus vs Annie Matchup?

Nautilus wins the Nautilus vs Annie matchup
Winner
Nautilus
Matches: 6
66.7%
Win Rate
33.3%
1.6
CS / min
2.0
384
DMG / min
609
9,170
Gold / game
9,112
106
Heal / min
51
1,212
DMG Mitigated / min
338
2.0
CC / min
1.0
50.0%
Early Game WR
50.0%
100.0%
Late Game WR
0.0%

Nautilus vs Annie Matchup Summary

The Nautilus vs Annie matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Nautilus wins with a 66.7% win rate compared to Annie's 33.3%, giving Nautilus a 33.3 percentage point advantage. Nautilus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Annie players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Nautilus leads by 930 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Nautilus players can confidently pick into Annie and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Annie away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Nautilus vs Annie Laning Phase Breakdown

Nautilus wins the laning phase against Annie in League of Legends

Nautilus is favored during the laning phase against Annie, winning 3 out of 5 key stat categories. Nautilus holds advantages in gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
1.6Nautilus
2.0Annie
Annie edges out Nautilus by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Annie.
Damage
384Nautilus
609Annie
Annie heavily out-damages Nautilus by 225 DMG/min, dominating both short trades and all-in fights. Nautilus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
9,170Nautilus
9,112Annie
Nautilus and Annie generate nearly equal gold per game, with just a 58 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
2.0Nautilus
1.0Annie
Nautilus brings significantly more crowd control than Annie, with 1.0 more seconds of CC per minute. This large utility gap makes Nautilus far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Annie should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
1,319Nautilus
389Annie
Nautilus vastly out-sustains Annie, healing and mitigating 930 more damage per minute. This massive durability gap means Nautilus can absorb significant punishment and remain in lane while Annie is forced to recall. Building grievous wounds early is essential for Annie, and focusing on burst trade patterns rather than sustained fights is critical.

Best Nautilus Build Against Annie

Mercury's Treads is the optimal boots choice against Annie, providing the mobility and stats Nautilus needs most in this matchup. The top-performing core items for Nautilus against Annie are Locket of the Iron Solari, Knight's Vow and Thornmail. This combination gives Nautilus an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Annie. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Nautilus vs Annie matchup.

Early Game vs Late Game

Early Game
Nautilus
50.0%
+0.0% advantage
Nautilus early game win rateNautilus50.0%
Annie early game win rateAnnie50.0%
Late Game
Nautilus
100.0%
+100.0% advantage
Nautilus late game win rateNautilus100.0%
Annie late game win rateAnnie0.0%

The early game (first 15 minutes) is a toss-up between Nautilus and Annie, with Nautilus holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Nautilus is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Annie. Extended games heavily favor Nautilus, whose kit and scaling make them a dominant force in team fights and objective control.

Nautilus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Annie players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Nautilus Runes Against Annie

Resolve rune tree - Nautilus primary runes vs AnnieResolve
Aftershock - best Nautilus rune vs AnnieShield Bash - best Nautilus rune vs AnnieBone Plating - best Nautilus rune vs AnnieUnflinching - best Nautilus rune vs Annie
Inspiration rune tree - Nautilus secondary runes vs AnnieInspiration
Hextech Flashtraption - best Nautilus rune vs AnnieCosmic Insight - best Nautilus rune vs Annie
100.0% WR

Running Resolve primary with Inspiration secondary allows Nautilus to press their advantage against Annie, amplifying the strengths that make this a favorable matchup.


Nautilus matchup data for League of Legends patch 26.12. The table below shows Nautilus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Nautilus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Nautilus matchup win rates and stats in League of Legends patch 26.12
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.34%2071.13478,18951.5%43.3%
48.28%2031.13448,52842.2%53.1%
50.28%1771.13668,54145.8%53.3%
49.08%1631.13678,43748.8%49.4%
42.19%1281.13438,63235.2%47.3%
44.92%1181.13608,85646.9%43.5%
55.75%1131.13578,27459.7%51.0%
50.00%1101.13899,02947.7%51.5%
50.53%951.13898,63141.5%57.4%
54.55%881.13548,50166.7%44.9%
59.30%861.03618,70658.1%60.0%
53.66%821.13808,87942.9%65.0%
48.72%781.13718,45445.2%52.8%
47.22%721.13438,86062.1%37.2%
39.44%710.94158,58239.4%39.5%
46.48%711.13178,06563.9%28.6%
53.62%691.03829,17437.5%62.2%
51.47%681.03928,12554.0%48.4%
60.00%651.12998,44960.0%60.0%
43.75%641.13418,59751.6%36.4%
53.23%621.13428,85450.0%55.3%
46.77%621.13498,69537.0%54.3%
57.63%591.14378,57451.7%63.3%
51.72%581.34419,21048.0%54.5%
46.55%581.13568,95248.1%45.2%
48.98%491.03708,70155.6%45.2%
44.68%471.13428,10334.8%54.2%
39.13%461.13928,49447.8%30.4%
44.74%381.14249,37233.3%50.0%
52.78%360.93628,39950.0%55.6%
42.86%351.23918,85240.0%45.0%
40.00%301.03739,07757.1%25.0%
66.67%301.13958,14464.3%68.8%
42.31%261.03989,03635.7%50.0%
53.85%261.24159,51658.3%50.0%
38.10%211.03338,55255.6%25.0%
66.67%211.147610,69650.0%73.3%
50.00%181.44508,66750.0%50.0%
44.44%181.74118,93212.5%70.0%
33.33%181.13378,49757.1%18.2%
58.82%171.13228,60257.1%60.0%
35.71%141.24238,97662.5%0.0%
36.36%111.03369,05640.0%33.3%
50.00%101.44439,65560.0%40.0%
50.00%102.55578,10037.5%100.0%
70.00%101.44007,269100.0%40.0%
70.00%101.04567,71771.4%66.7%
70.00%100.84619,38980.0%60.0%
30.00%101.43828,83825.0%33.3%
66.67%91.03559,58650.0%71.4%
25.00%81.14326,48228.6%0.0%
37.50%82.15187,48637.5%0.0%
37.50%80.64349,79350.0%0.0%
62.50%81.43167,98040.0%100.0%
37.50%82.34859,32225.0%50.0%
57.14%71.24149,63840.0%100.0%
66.67%61.162511,12966.7%66.7%
66.67%61.14489,36950.0%100.0%
66.67%61.44197,87666.7%66.7%
66.67%61.63849,17050.0%100.0%
16.67%61.54299,9180.0%25.0%
50.00%61.155212,6750.0%60.0%
50.00%61.15519,61550.0%50.0%
50.00%61.14459,85150.0%50.0%
66.67%61.33529,91050.0%75.0%
50.00%61.24198,62440.0%100.0%
40.00%51.735711,998100.0%25.0%
40.00%51.14588,0680.0%66.7%

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Nautilus vs Annie - Frequently Asked Questions

How does Nautilus do against Annie in League of Legends?

Nautilus wins the Nautilus vs Annie matchup with a 66.7% win rate compared to Annie's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.12.

How does Nautilus do against Annie in the early game?

In the early game, Nautilus has the advantage against Annie with a 50.0% win rate versus 50.0%. Nautilus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Nautilus do against Annie in the late game?

In the late game, Nautilus takes over the Nautilus vs Annie matchup with a 100.0% win rate compared to 0.0%. Nautilus scales better into team fights and objective contests after 25 minutes.

Who wins the Nautilus vs Annie matchup?

Nautilus wins the matchup against Annie with a 66.7% win rate in League of Legends patch 26.12. The 33.3 percentage point advantage means Nautilus is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Nautilus build against Annie?

The best Nautilus build against Annie includes Locket of the Iron Solari, Knight's Vow, Thornmail with Mercury's Treads. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Nautilus runes against Annie?

The best Nautilus runes against Annie use the Resolve primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Nautilus vs Annie matchup. See the full rune breakdown in the matchup comparison above.

Does Nautilus counter Annie?

Yes, Nautilus has a favorable matchup against Annie with a 66.7% win rate. Nautilus strongly counters Annie in lane based on current patch 26.12 data.

How do I play Nautilus against Annie?

When playing Nautilus against Annie, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.