Cassiopeia, League of Legends champion
Win Rate
45.9%
Pick Rate
0.1%
Ban Rate
0.7%

Cassiopeia Top Runes: Keystone & Shards

Cassiopeia F TierMage
Patch
26.20
Games
290
Lane
Top
Tier
All Tiers
Last Updated
Oct 17, 2026 UTC
Methodology
Data Methodology

Best Top Cassiopeia runes for LoL Patch 26.20 - Conqueror from the Precision tree with Sorcery secondary (48.1% WR, 27.2% pick rate). Cassiopeia's optimal primary runes are Conqueror, Presence of Mind, Legend: Haste, Last Stand. Secondary tree: Manaflow Band, Transcendence.

Cassiopeia performs best with Conqueror as the keystone rune from the Precision tree. Cassiopeia's optimal primary runes are Conqueror, Presence of Mind, Legend: Haste, Last Stand. Cassiopeia's secondary rune tree is Sorcery with Manaflow Band, Transcendence. This rune setup achieves a 48.10% win rate (+2.2% win rate difference) with a 27.2% pick rate across 79 Cassiopeia games.
48.1%Win Rate
+2.2%WR Diff
27.2%Pick Rate
ConquerorConqueror

Basic attacks or spells that deal damage to an enemy champion grant 2 stacks of Conqueror for 5s, gaining 1.8-4 Adaptive Force per stack. Stacks up to 12 times. Ranged champions gain only 1 stack per basic attack.

When fully stacked, heal for 8% of the damage you deal to champions (5% for ranged champions).

Presence of MindPresence of Mind

Damaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.

Takedowns restore 15% of your maximum mana or energy.

Cooldown for damage restoration: 8s

Legend: HasteLegend: Haste

Gain 1.5 basic ability haste for every Legend stack (max 10 stacks).

Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.

Last StandLast Stand

Deal 5% - 11% increased damage to champions while you are below 60% health. Max damage gained at 30% health.

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

TranscendenceTranscendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.

This alternative Cassiopeia rune build uses Deathfire Touch as the keystone from the Sorcery tree. The primary runes are Deathfire Touch, Manaflow Band, Transcendence, Scorch. Cassiopeia's secondary rune tree is Precision with Coup de Grace, Presence of Mind. This setup achieves a 42.86% win rate (-3.0% win rate difference) with a 29.0% pick rate across 84 games.
42.9%Win Rate
-3.0%WR Diff
29.0%Pick Rate
Deathfire TouchDeathfire Touch

Damaging a champion with an ability burns them for 3 - 12 based on level (+2.5% AP) (+7% bonus AD) magic damage per second. After burning for 3 seconds, the damage of the burn increases by 75% while they remain on fire.

Duration:
Single Target: 4s
Area of Effect: 2s
Damage over Time: 1s

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

TranscendenceTranscendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

Coup de GraceCoup de Grace

Deal 8% more damage to champions who have less than 40% health.

Presence of MindPresence of Mind

Damaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.

Takedowns restore 15% of your maximum mana or energy.

Cooldown for damage restoration: 8s

These champions share at least 4 runes with Cassiopeia's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Cassiopeia's playstyle or want to learn champions with familiar rune setups.Pantheon, Gragas, Mordekaiser

Every Cassiopeia Top Keystone and Secondary Tree (Patch 26.20)

279 games

Cassiopeia Top runs Deathfire Touch in 49% of games, with a 41.9% win rate. Precision is the usual secondary tree (58%). Standard stat shards: Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense).

Keystones

RunePlayersWin RateGames
Deathfire TouchDeathfire TouchMost played48.7%41.9%136
ConquerorConqueror38.7%49.1%108

Secondary trees

RunePlayersWin RateGames
PrecisionPrecisionMost played58.1%44.4%162
SorcerySorcery37.3%50.0%104

Pick rate is the share of Cassiopeia games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.

Cassiopeia Minor Runes by Tree

Every minor rune Cassiopeia players take, grouped by rune tree, with how often it is picked and how often it wins.

Sorcery

RunePlayersWin RateGames
Manaflow BandManaflow BandMost played91.0%46.1%254
TranscendenceTranscendence82.1%44.5%229
ScorchScorch58.4%42.9%163

Precision

RunePlayersWin RateGames
Presence of MindPresence of MindMost played91.0%47.2%254
Coup de GraceCoup de Grace50.5%45.4%141
Legend: HasteLegend: Haste43.4%46.3%121
Last StandLast Stand34.8%50.5%97

Cassiopeia Stat Shards

Which stat shards Cassiopeia players choose in each of the three shard rows, and the win rate of each.

RunePlayersWin RateGames
Adaptive Force (flex)Adaptive Force (flex)Most played92.1%45.1%257
Adaptive Force (offense)Adaptive Force (offense)91.0%45.3%254
Health Scaling (defense)Health Scaling (defense)88.9%45.6%248
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Cassiopeia Runes FAQ - Patch 26.20

What is the best keystone for Cassiopeia Top?

Deathfire Touch: Cassiopeia Top takes it in 49% of ranked games and wins 41.9% of 136 games. Alternatives: Conqueror (39%, 49.1%).

What stat shards should Cassiopeia take?

Most Cassiopeia players take Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.

What are the best Cassiopeia runes in patch 26.20?

The best Cassiopeia runes in patch 26.20 use the Precision tree with Conqueror, Presence of Mind, Legend: Haste, and Last Stand, and the Sorcery tree with Manaflow Band and Transcendence. This rune setup achieves a 48.1% win rate with a 27.2% pick rate.

What is the win rate for Cassiopeia's best rune page?

Cassiopeia's best rune page has a 48.1% win rate in patch 26.20, which is +2.2% compared to Cassiopeia's average win rate. This rune setup has a 27.2% pick rate among Cassiopeia players.

What keystone should I use on Cassiopeia?

Conqueror from the Precision tree is the best keystone rune for Cassiopeia in patch 26.20. This keystone synergizes well with Cassiopeia's kit and provides a 48.1% win rate.

What is Cassiopeia's primary rune tree?

Cassiopeia's primary rune tree is Precision. The optimal Precision runes for Cassiopeia are Conqueror, Presence of Mind, Legend: Haste, and Last Stand, with Conqueror being the keystone of choice.

What is Cassiopeia's secondary rune tree?

Cassiopeia's best secondary rune tree is Sorcery. The recommended Sorcery runes are Manaflow Band and Transcendence, which complement Cassiopeia's Precision primary tree.

What are alternative rune setups for Cassiopeia?

An alternative Cassiopeia rune setup uses Deathfire Touch from the Sorcery tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Cassiopeia's runes?

Cassiopeia's top rune page has a 27.2% pick rate in patch 26.20. This indicates that 27.2% of Cassiopeia players use the Conqueror setup with Precision and Sorcery trees.